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126_kDa_replicase

Euk-Vir

Maracuja_mosaic_virus

126_kDa_replicase__YP_950421__Maracuja_mosaic_virus__368736

Identity

Accession:: YP_950421 ↗
Protein ID:: 126_kDa_replicase
Kingdom:: euk

Quality

73.5 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Virgaviridae› Tobamovirus› Maracuja_mosaic_virus

TaxID: 368736

Cluster

View cluster (21 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 666-803

PDB

Domain cluster: rep: replicase__NP_059451__Soil-borne_cereal_mosaic_virus__100887__D845-991

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF20896.3 best	ToMV_Hel_N	28.4	2.30e-06	74.6%	61.4%

D2 high residues 811-948

PDB

Domain cluster: rep: KX578043.1__AOT27930.1__X__00015__D87-267

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01443.25 best	Viral_helicase1	83.2	3.60e-23	93.5%	48.7%

D3 high residues 957-1095

PDB

Domain cluster: rep: TGB1_protein__NP_619560__Garlic_latent_virus__12458__D129-228

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01443.25 best	Viral_helicase1	67.8	1.80e-18	82.0%	44.7%

D4 medium residues 20-101

PDB

Domain cluster: rep: 1a_protein__YP_002640500__Gayfeather_mild_mottle_virus__578305__D32-94

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3c5vA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.59	42.0	2.89e-01	73.2%	86.7%
4f2gA01	3.40.50.1370	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase	0.59	40.0	3.38e-01	72.0%	76.2%
3wxmB02	3.30.420.60	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2	0.58	34.0	2.97e-01	74.4%	39.3%
4pg4A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.57	40.0	3.29e-01	74.4%	96.9%
2q02A00	3.20.20.150	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes	0.57	39.0	2.84e-01	74.4%	98.5%
2bmjA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	42.0	3.31e-01	82.9%	100.0%
3bdiA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.54	39.0	2.99e-01	78.0%	89.9%
2vk2A01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.54	38.0	3.31e-01	74.4%	94.7%
3wzlA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	37.0	2.69e-01	76.8%	93.2%
6wgmA00	3.40.190.170	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7	0.51	42.0	2.86e-01	91.5%	83.2%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3601038	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.61	42.0	3.26e-01	72.0%	92.1%
4154217	7512.1.1.0 ↗	a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase	0.59	42.0	3.25e-01	75.6%	84.2%
4436750	2003.1.5.27 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS	0.57	39.0	2.72e-01	72.0%	63.4%
3969609	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.53	38.0	3.21e-01	78.0%	82.7%
4983668	7522.1.1.4 ↗	a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II	0.52	39.0	3.31e-01	79.3%	94.1%
3388129	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.52	41.0	3.27e-01	87.8%	92.8%
1155927	323.1.1.3 ↗	a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding	0.52	38.0	3.29e-01	79.3%	90.5%
2166158	2007.1.14.7 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › HGD-D	0.52	40.0	3.12e-01	87.8%	76.0%
3280617	7579.1.1.0 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases	0.51	40.0	2.77e-01	85.4%	27.7%

D5 medium residues 102-148_174-242_295-378

PDB

D6 medium residues 243-294

PDB

Domain cluster: rep: replicase__NP_059511__Oat_golden_stripe_virus__45103__D252-303

D7 medium residues 379-422_437-480

PDB

Domain cluster: rep: uncovered_polypeptide_polyprotein__YP_004464917_245-428__Cutthroat_trout_virus__1016879__D45-170

D8 medium residues 423-436_481-543

PDB