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20L_protein
Euk-VirYaba-like_disease_virus
20L_protein__NP_073405__Yaba-like_disease_virus__132475
Identity
- Accession:
- NP_073405 ↗
- Protein ID:
- 20L_protein
- Kingdom:
- euk
Quality
84.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Yatapoxvirus›
Yaba-like_disease_virus
TaxID: 132475
Cluster
View cluster (111 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 49-222
Domain cluster:
rep: ribonucleotide_reductase_subunit_2__YP_009052007__Elephant_endotheliotropic_herpesvirus_5__768738__D11-211
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 254.0 | 2.60e-75 | 100.0% | 61.6% |
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.99 | 98.0 | 7.92e-01 | 100.0% | 60.4% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.94 | 92.0 | 7.21e-01 | 100.0% | 61.2% |
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.94 | 75.0 | 6.65e-01 | 100.0% | 61.2% |
| 4bmoA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.92 | 89.0 | 7.28e-01 | 100.0% | 64.1% |
| 6eboA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.89 | 85.0 | 6.81e-01 | 100.0% | 57.2% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 72.0 | 6.68e-01 | 96.0% | 72.0% |
| 2oc5A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.85 | 72.0 | 6.64e-01 | 96.0% | 71.6% |
| 1mhyD00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.84 | 79.0 | 5.50e-01 | 100.0% | 47.3% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.83 | 68.0 | 7.27e-01 | 91.4% | 97.3% |
| 3u52D00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.81 | 77.0 | 6.09e-01 | 100.0% | 68.6% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.81 | 69.0 | 6.58e-01 | 94.8% | 78.2% |
| 1rtwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.79 | 69.0 | 6.50e-01 | 96.6% | 76.9% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 60.0 | 6.70e-01 | 90.2% | 100.0% |
| 1dpsA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 65.0 | 6.83e-01 | 96.0% | 95.0% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 62.0 | 6.75e-01 | 88.5% | 100.0% |
| 1to9A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.77 | 68.0 | 6.18e-01 | 96.6% | 72.4% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 65.0 | 6.90e-01 | 94.8% | 100.0% |
| 1evsA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.76 | 54.0 | 5.60e-01 | 74.1% | 77.3% |
| 4mudC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 72.0 | 6.57e-01 | 100.0% | 98.2% |
| 1uddA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.76 | 65.0 | 6.08e-01 | 96.6% | 74.4% |
| 3oqlC00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.75 | 68.0 | 6.08e-01 | 96.6% | 72.3% |
| 3pvtA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 70.0 | 5.74e-01 | 99.4% | 73.4% |
| 3qhbA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 63.0 | 6.31e-01 | 92.0% | 87.7% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 59.0 | 6.07e-01 | 96.0% | 88.6% |
| 1lb3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 61.0 | 6.25e-01 | 98.3% | 91.0% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.72 | 51.0 | 4.96e-01 | 71.3% | 100.0% |
| 1otkA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 65.0 | 5.71e-01 | 95.4% | 86.1% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.66 | 44.0 | 4.59e-01 | 97.7% | 70.3% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 38.0 | 4.50e-01 | 92.0% | 81.0% |
| 1xlyA00 | 1.20.200.20 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › She2 domain | 0.61 | 46.0 | 4.20e-01 | 98.9% | 59.8% |
| 5tj5E00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.57 | 36.0 | 4.00e-01 | 92.5% | 78.3% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.56 | 42.0 | 4.33e-01 | 96.6% | 81.6% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 41.0 | 3.82e-01 | 78.7% | 64.3% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 46.0 | 4.50e-01 | 98.3% | 84.8% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4603349 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 1.00 | 99.0 | 7.40e-01 | 100.0% | 49.3% |
| 3470297 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 1.00 | 99.0 | 7.53e-01 | 100.0% | 51.9% |
| 3274715 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.98 | 81.0 | 7.39e-01 | 85.6% | 67.9% |
| 162837 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.95 | 88.0 | 7.18e-01 | 100.0% | 57.6% |
| 4026999 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.93 | 90.0 | 7.14e-01 | 100.0% | 56.8% |
| 4340194 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 89.0 | 7.15e-01 | 100.0% | 60.7% |
| 354818 | 150.1.2.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Phenol_Hydrox | 0.85 | 81.0 | 5.65e-01 | 100.0% | 35.9% |
| 3281880 | 150.1.2.12 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › MiaE_2 | 0.80 | 68.0 | 6.32e-01 | 97.1% | 72.4% |
| 5010070 | 150.1.2.7 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › PaaA_PaaC | 0.77 | 72.0 | 6.36e-01 | 100.0% | 90.2% |
| 4194775 | 150.1.1.4 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › COQ7 | 0.76 | 67.0 | 6.49e-01 | 97.1% | 83.1% |
| 3606445 | 150.1.1.4 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › COQ7 | 0.73 | 68.0 | 6.55e-01 | 100.0% | 88.2% |
| 3411210 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 51.0 | 4.90e-01 | 70.7% | 94.4% |
| 4879185 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.71 | 64.0 | 5.82e-01 | 97.1% | 72.6% |
| 4009779 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.70 | 44.0 | 4.96e-01 | 97.7% | 80.0% |
| 4360597 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.68 | 40.0 | 4.12e-01 | 90.8% | 59.4% |
| 4393627 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.68 | 40.0 | 4.11e-01 | 90.8% | 59.4% |
| 3436831 | 601.4.1.52 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Auxin_canalis | 0.66 | 43.0 | 4.83e-01 | 77.6% | 86.2% |
| 3237916 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 49.0 | 4.88e-01 | 75.9% | 83.8% |
| 3223368 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 48.0 | 5.07e-01 | 75.3% | 83.2% |
| 3485403 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.65 | 45.0 | 4.45e-01 | 94.8% | 66.1% |
| 3729395 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.65 | 47.0 | 5.37e-01 | 73.6% | 97.7% |
| 4565794 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 41.0 | 4.59e-01 | 89.7% | 78.6% |
| 3312807 | 3922.1.1.7 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Auxin_canalis | 0.65 | 42.0 | 4.55e-01 | 77.6% | 76.6% |
| 3827271 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.65 | 40.0 | 4.53e-01 | 90.8% | 80.8% |
| 3671851 | 5086.1.1.47 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Auxin_canalis | 0.65 | 42.0 | 4.63e-01 | 77.6% | 82.2% |
| 3399701 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.64 | 47.0 | 5.15e-01 | 74.1% | 94.3% |
| 3717920 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.64 | 48.0 | 5.14e-01 | 77.6% | 90.3% |
| 3711300 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 42.0 | 4.52e-01 | 97.7% | 77.4% |
| 3916675 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.60 | 45.0 | 4.61e-01 | 77.0% | 97.1% |
| 3245184 | 601.14.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › PF31009 | 0.60 | 44.0 | 4.79e-01 | 74.7% | 95.9% |
| 3578008 | 601.1.2.100 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF31009 | 0.59 | 43.0 | 4.60e-01 | 75.3% | 88.4% |
| 5041183 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.59 | 43.0 | 4.27e-01 | 93.1% | 71.7% |
| 3712717 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.59 | 41.0 | 4.33e-01 | 93.7% | 79.4% |
| 3989931 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.59 | 46.0 | 4.41e-01 | 94.3% | 72.3% |
| 3799484 | 633.26.1.3 ↗ | alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain › PF31009 | 0.58 | 43.0 | 4.43e-01 | 75.9% | 84.2% |
| 3713307 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 41.0 | 4.33e-01 | 93.7% | 81.3% |
| 3236017 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 42.0 | 4.65e-01 | 74.7% | 100.0% |
| 3408341 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.57 | 42.0 | 4.32e-01 | 75.3% | 98.2% |
| 3416952 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 42.0 | 4.66e-01 | 74.7% | 97.8% |
| 3235726 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.57 | 43.0 | 4.53e-01 | 81.0% | 85.6% |
| 4681797 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.56 | 46.0 | 4.43e-01 | 86.8% | 86.5% |
| 4941651 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.56 | 44.0 | 4.26e-01 | 83.3% | 89.0% |
| 3834443 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.55 | 49.0 | 4.32e-01 | 94.8% | 92.7% |
| 3220791 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.55 | 43.0 | 4.26e-01 | 83.3% | 79.5% |
| 3606314 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.54 | 47.0 | 3.82e-01 | 91.4% | 89.4% |
| 5082391 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.54 | 44.0 | 4.27e-01 | 87.4% | 91.5% |
| 3587115 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.53 | 46.0 | 3.76e-01 | 90.8% | 87.9% |
| 5053276 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.53 | 45.0 | 4.15e-01 | 89.7% | 85.9% |
| 3938965 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 42.0 | 3.80e-01 | 89.7% | 79.2% |
D2
medium
residues 223-292
Domain cluster:
rep: ORF54__NP_733908__Callitrichine_gammaherpesvirus_3__106331__D213-276
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 68.9 | 6.80e-19 | 85.7% | 21.7% |