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2C
Euk-VirCosavirus_E
2C__YP_002956083__Cosavirus_E__2003651
Identity
- Accession:
- YP_002956083 ↗
- Protein ID:
- 2C
- Kingdom:
- euk
Quality
85.2
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Picornavirales›
Picornaviridae›
Cosavirus›
Cosavirus_E
TaxID: 2003651
Cluster
View cluster (62 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 46-102
Domain cluster:
representative
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ceqA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.76 | 59.0 | 3.86e-01 | 100.0% | 19.6% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.75 | 60.0 | 4.09e-01 | 100.0% | 25.7% |
| 2ifuD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.75 | 60.0 | 3.84e-01 | 100.0% | 18.5% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.74 | 65.0 | 4.33e-01 | 100.0% | 26.6% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.73 | 63.0 | 5.26e-01 | 100.0% | 60.8% |
| 4gywA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 52.0 | 4.26e-01 | 100.0% | 41.9% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 53.0 | 4.69e-01 | 80.7% | 97.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.71 | 60.0 | 4.87e-01 | 100.0% | 57.8% |
| 4hbdA00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.70 | 61.0 | 3.99e-01 | 98.2% | 30.2% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 48.0 | 4.50e-01 | 77.2% | 60.0% |
| 4g1tA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 55.0 | 4.26e-01 | 100.0% | 41.5% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.67 | 53.0 | 5.33e-01 | 98.2% | 91.2% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 53.0 | 4.67e-01 | 98.2% | 84.7% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.66 | 56.0 | 4.42e-01 | 100.0% | 81.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.65 | 54.0 | 4.98e-01 | 100.0% | 82.3% |
| 2dbaA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 46.0 | 3.74e-01 | 100.0% | 38.1% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 52.0 | 5.09e-01 | 98.2% | 87.3% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.63 | 45.0 | 3.29e-01 | 78.9% | 41.7% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.63 | 55.0 | 4.20e-01 | 94.7% | 45.2% |
| 1t3dA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.63 | 56.0 | 4.10e-01 | 96.5% | 67.9% |
| 3au3A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.63 | 52.0 | 3.38e-01 | 100.0% | 21.6% |
| 1p49A02 | 1.10.287.550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.61 | 44.0 | 4.44e-01 | 80.7% | 79.7% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 44.0 | 3.96e-01 | 80.7% | 85.1% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.61 | 50.0 | 3.58e-01 | 100.0% | 29.3% |
| 1x5bA01 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 49.0 | 3.89e-01 | 100.0% | 42.2% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.59 | 44.0 | 4.31e-01 | 80.7% | 76.6% |
| 3t57A02 | 1.20.1180.10 | Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain | 0.55 | 41.0 | 3.81e-01 | 100.0% | 62.7% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 46.0 | 3.82e-01 | 100.0% | 71.4% |
| 1w53A00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.53 | 43.0 | 3.90e-01 | 96.5% | 65.5% |
| 1cgnA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.52 | 43.0 | 3.45e-01 | 98.2% | 100.0% |
| 1hr6B02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.50 | 42.0 | 2.87e-01 | 93.0% | 62.5% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5002688 | 109.4.1.186 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ANAPC3 | 0.78 | 67.0 | 4.36e-01 | 96.5% | 25.8% |
| 3624841 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 62.0 | 4.91e-01 | 100.0% | 45.2% |
| 2825526 | 109.4.1.1300 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16, TPR_19 | 0.75 | 61.0 | 5.46e-01 | 100.0% | 64.9% |
| 4848264 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.75 | 62.0 | 5.41e-01 | 96.5% | 59.8% |
| 1148717 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.74 | 60.0 | 5.49e-01 | 100.0% | 66.7% |
| 3818267 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 62.0 | 4.98e-01 | 100.0% | 56.4% |
| 3712232 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.69 | 51.0 | 4.09e-01 | 82.5% | 41.7% |
| 3940780 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 56.0 | 4.80e-01 | 96.5% | 83.0% |
| 3959035 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 58.0 | 4.27e-01 | 100.0% | 34.5% |
| 3997366 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.67 | 48.0 | 3.19e-01 | 78.9% | 22.4% |
| 3737781 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.67 | 56.0 | 4.74e-01 | 100.0% | 72.4% |
| 4975727 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.67 | 52.0 | 4.31e-01 | 94.7% | 46.7% |
| 3815026 | 604.1.1.148 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N | 0.67 | 56.0 | 5.06e-01 | 100.0% | 84.7% |
| 5017179 | 604.17.1.1 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like › DUF447_C | 0.66 | 51.0 | 5.36e-01 | 100.0% | 100.0% |
| 3616671 | 604.1.1.155 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29142 | 0.66 | 55.0 | 4.80e-01 | 100.0% | 69.5% |
| 4934383 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.66 | 49.0 | 3.73e-01 | 82.5% | 33.6% |
| 3588291 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 48.0 | 4.38e-01 | 80.7% | 57.5% |
| 1910276 | 109.4.1.1499 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, TPR_19 | 0.65 | 53.0 | 4.88e-01 | 98.2% | 69.3% |
| 3898566 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.65 | 45.0 | 3.46e-01 | 75.4% | 58.6% |
| 3964543 | 601.2.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_C_2 | 0.63 | 53.0 | 4.25e-01 | 98.2% | 83.2% |
| 4363138 | 192.29.1.125 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cytochrom_C_asm | 0.62 | 54.0 | 3.49e-01 | 100.0% | 33.8% |
| 5016654 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.62 | 42.0 | 4.12e-01 | 75.4% | 64.6% |
| 3987865 | 5086.1.1.192 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7649 | 0.61 | 44.0 | 4.01e-01 | 82.5% | 58.8% |
| 3251268 | 601.7.1.16 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN_Swt1 | 0.60 | 54.0 | 3.78e-01 | 94.7% | 75.6% |
| 3364871 | 3711.1.1.4 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 | 0.58 | 48.0 | 3.31e-01 | 98.2% | 93.3% |
| 3237792 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.53 | 41.0 | 3.82e-01 | 94.7% | 65.3% |
| 5060253 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.53 | 41.0 | 3.92e-01 | 86.0% | 72.3% |
D2
high
residues 114-308
Domain cluster:
rep: replication_associated_protein__YP_009345107__Amphibola_crenata_associated_bacilladnavirus_1__1941435__D302-478
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00910.29 best | RNA_helicase | 107.0 | 9.90e-31 | 52.3% | 99.1% |