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2a_protein

Euk-Vir

Peanut_stunt_virus

2a_protein__NP_049332__Peanut_stunt_virus__12313

Identity

Accession:
NP_049332 ↗
Protein ID:
2a_protein
Kingdom:
euk

Quality

68.1 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Bromoviridae› Cucumovirus› Peanut_stunt_virus

TaxID: 12313

Cluster

View cluster (23 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 641-747
PDB
Domain cluster: rep: 2a_protein__YP_009551509__Sambucus_virus_S__2052851__D633-716
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 56.9 2.50e-15 84.1% 18.4%
D2 medium residues 267-354
PDB
Domain cluster: rep: 2a_protein__YP_002640501__Gayfeather_mild_mottle_virus__578305__D283-311_333-372
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 47.1 2.40e-12 68.2% 13.6%
D3 medium residues 483-508_583-634
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase,_partial__YP_002364303__Grapevine_leafroll-associated_virus_10__367121__D252-284_355-434
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 62.8 4.10e-17 66.7% 11.8%
D4 medium residues 509-582
PDB
Domain cluster: rep: RNA_polymerase__YP_009551568__Tea_plant_line_pattern_virus__2419940__D443-495
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 109.1 3.60e-31 100.0% 16.8%
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1cukA03 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.66 37.0 4.46e-01 78.4% 85.4%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.66 45.0 3.12e-01 97.3% 21.8%
2zhgA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.64 38.0 3.24e-01 81.1% 35.5%
3hlbD00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.57 48.0 3.11e-01 100.0% 36.9%
2hnhA03 1.10.10.1600 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Bacterial DNA polymerase III alpha subunit, thumb domain 0.56 47.0 4.64e-01 93.2% 89.7%
2hg7A00 3.30.56.60 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › XkdW-like 0.55 40.0 4.30e-01 95.9% 95.0%
2is6A04 1.10.486.10 Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 0.55 45.0 3.58e-01 94.6% 42.9%
3f0zA02 1.10.340.30 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Hypothetical protein; domain 2 0.54 43.0 3.77e-01 91.9% 73.6%
1y0nA00 1.10.10.610 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › YehU-like 0.53 36.0 3.66e-01 98.6% 71.8%
2e9yB00 3.40.1160.10 Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like 0.53 42.0 2.82e-01 87.8% 78.5%
2felA00 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.53 45.0 3.01e-01 100.0% 57.9%
2q0yA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 45.0 3.73e-01 98.6% 72.5%
2pmeA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 42.0 2.74e-01 86.5% 44.8%
3fvvA02 1.20.1440.100 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function 0.52 41.0 4.17e-01 97.3% 90.7%
7x4eA01 1.10.1220.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › DNA sulphur modification protein DndE 0.52 40.0 3.64e-01 87.8% 96.3%
3axsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 40.0 2.74e-01 89.2% 32.0%
3kksB00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 42.0 3.44e-01 94.6% 86.8%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.51 44.0 4.14e-01 100.0% 84.2%
8agaA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 41.0 3.49e-01 90.5% 82.5%
2hoeA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 32.0 3.62e-01 86.5% 84.5%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3983816 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.77 66.0 4.55e-01 100.0% 28.4%
3251965 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.76 68.0 4.74e-01 100.0% 30.8%
3674655 2003.1.9.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins 0.76 69.0 4.03e-01 100.0% 13.0%
3650065 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.75 67.0 4.58e-01 100.0% 28.5%
3258201 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 66.0 4.62e-01 100.0% 31.5%
4289835 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.74 66.0 4.74e-01 100.0% 35.2%
3651060 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.73 65.0 4.79e-01 100.0% 38.9%
3272304 304.36.1.2 ↗ a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › RVT_1 0.72 59.0 4.75e-01 90.5% 46.2%
3911603 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.71 64.0 4.91e-01 100.0% 67.9%
4003509 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.68 60.0 4.76e-01 100.0% 78.1%
4000704 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.61 52.0 3.99e-01 100.0% 60.0%
3357805 3887.2.1.1 ↗ a+b two layers › Yeast killer toxin-like › Antifungal protein ginkbilobin-2 › Antifungal protein ginkbilobin-2 › Stress-antifung 0.60 43.0 4.32e-01 74.3% 97.3%
4161499 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.60 45.0 4.42e-01 100.0% 75.0%
3274487 605.1.1.155 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Gpi1 0.59 47.0 3.58e-01 86.5% 80.6%
4202123 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.58 43.0 4.26e-01 100.0% 75.0%
4507562 4203.1.1.1 ↗ few secondary structure elements › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 redox switch-like › HSP33 0.57 30.0 3.42e-01 74.3% 67.3%
4143313 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.55 41.0 3.99e-01 100.0% 70.6%
2420873 102.1.2.21 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › DNA-glycosylase › MJ0043_C 0.55 44.0 4.07e-01 93.2% 68.4%
3990521 5050.1.1.31 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr 0.55 43.0 3.37e-01 89.2% 70.9%
3608029 1189.1.1.0 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.54 45.0 2.94e-01 98.6% 84.1%
4880209 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 44.0 3.27e-01 94.6% 52.0%
4179317 3236.1.1.5 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_antiport_1 0.53 39.0 2.53e-01 79.7% 73.5%
3380974 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 42.0 2.81e-01 91.9% 31.6%
4113442 101.26.1.2 ↗ alpha arrays › HTH › Tex N-terminal domain › Tex N-terminal domain › HTH_44 0.52 45.0 3.64e-01 98.6% 72.4%
2325410 1074.1.1.2 ↗ alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgN,RNR_N 0.52 40.0 3.18e-01 97.3% 39.8%
10885 7581.1.1.11 ↗ a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › HMG_CoA_synt_C 0.50 41.0 2.95e-01 90.5% 36.2%