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39L_protein
Euk-VirYaba-like_disease_virus
39L_protein__NP_073424__Yaba-like_disease_virus__132475
Identity
- Accession:
- NP_073424 ↗
- Protein ID:
- 39L_protein
- Kingdom:
- euk
Quality
84.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Yatapoxvirus›
Yaba-like_disease_virus
TaxID: 132475
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 162-344
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__YP_401712__Human_gammaherpesvirus_4__10376__D288-457
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 81.8 | 7.30e-23 | 100.0% | 69.8% |
D2
high
residues 349-434
Domain cluster:
rep: DNA_polymerase_elongation_subunit_family_B__YP_009162448__Salmon_gill_poxvirus__1680908__D388-474
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08408.17 best | DNA_pol_B_3 | 88.8 | 4.70e-25 | 98.8% | 66.4% |
D3
high
residues 831-998
Domain cluster:
rep: IMGVR_UViG_3300021255_003095-3300021255-Ga0223825_1010595139__D209-342
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 113.6 | 1.50e-32 | 93.5% | 32.7% |
D4
medium
residues 467-524_621-666
Domain cluster:
rep: DNA_polymerase__YP_009701657__Heliothis_virescens_ascovirus_3g__1246651__D458-502_713-751
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 53.4 | 2.70e-14 | 51.0% | 11.3% |
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 42.0 | 4.48e-01 | 81.7% | 60.2% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.76 | 66.0 | 5.73e-01 | 92.3% | 83.0% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 41.0 | 4.78e-01 | 81.7% | 74.7% |
| 1ng6A01 | 1.10.1510.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Protein Yqey; Chain: A; domain1 › Uncharacterised protein YqeY/AIM41, N-terminal domain | 0.70 | 48.0 | 5.05e-01 | 91.3% | 80.2% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.67 | 47.0 | 3.89e-01 | 71.2% | 60.7% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 44.0 | 4.29e-01 | 79.8% | 59.8% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 46.0 | 4.59e-01 | 86.5% | 68.5% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.63 | 39.0 | 4.22e-01 | 71.2% | 73.6% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 51.0 | 4.42e-01 | 85.6% | 82.7% |
| 2vzbB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 50.0 | 4.18e-01 | 85.6% | 75.4% |
| 1uaaA02 | 1.10.10.160 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.61 | 32.0 | 3.75e-01 | 94.2% | 71.6% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 50.0 | 4.32e-01 | 85.6% | 78.9% |
| 1dpsA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 50.0 | 4.25e-01 | 85.6% | 78.6% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 49.0 | 4.12e-01 | 85.6% | 74.9% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.60 | 38.0 | 3.79e-01 | 89.4% | 61.3% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 47.0 | 4.10e-01 | 82.7% | 80.7% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 50.0 | 4.42e-01 | 89.4% | 90.3% |
| 3juiA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 41.0 | 3.52e-01 | 84.6% | 43.7% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 48.0 | 4.37e-01 | 89.4% | 66.7% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 49.0 | 4.37e-01 | 89.4% | 86.1% |
| 1umnG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 48.0 | 4.02e-01 | 85.6% | 77.6% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 47.0 | 4.13e-01 | 85.6% | 85.1% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 47.0 | 4.28e-01 | 85.6% | 83.7% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 46.0 | 3.78e-01 | 88.5% | 64.5% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 45.0 | 4.29e-01 | 85.6% | 82.0% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.56 | 47.0 | 3.56e-01 | 89.4% | 40.2% |
| 1txdA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.56 | 47.0 | 3.57e-01 | 89.4% | 46.3% |
| 1za0A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.56 | 50.0 | 3.74e-01 | 96.2% | 56.6% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.54 | 45.0 | 4.34e-01 | 95.2% | 78.2% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.54 | 45.0 | 4.20e-01 | 89.4% | 87.0% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 44.0 | 4.43e-01 | 88.5% | 92.5% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 41.0 | 3.14e-01 | 84.6% | 33.3% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 41.0 | 3.49e-01 | 84.6% | 48.9% |
| 1l8nA03 | 3.90.1330.10 | Alpha Beta › Alpha-Beta Complex › Alpha-d-glucuronidase, C-terminal Domain › Alpha-glucuronidase, C-terminal domain | 0.51 | 40.0 | 3.25e-01 | 85.6% | 74.6% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 39.0 | 3.37e-01 | 85.6% | 74.9% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 39.0 | 3.56e-01 | 86.5% | 87.2% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.89 | 84.0 | 4.98e-01 | 100.0% | 28.4% | |
| None | — | 0.87 | 81.0 | 4.87e-01 | 100.0% | 28.7% | |
| 3628202 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.85 | 79.0 | 4.71e-01 | 100.0% | 27.1% |
| 4022366 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.83 | 76.0 | 4.60e-01 | 100.0% | 28.7% |
| 3605750 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.82 | 76.0 | 4.35e-01 | 100.0% | 59.6% |
| 4942685 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.80 | 74.0 | 4.68e-01 | 100.0% | 36.7% |
| 3613133 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 43.0 | 4.79e-01 | 81.7% | 75.3% |
| 1487362 | 3930.2.1.1 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in endoribonuclease Dicer › Helical bundle in endoribonuclease Dicer › Dicer_PBD | 0.68 | 46.0 | 4.38e-01 | 92.3% | 59.7% |
| 3642678 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 48.0 | 4.01e-01 | 72.1% | 78.2% |
| 3245047 | 603.1.1.213 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29152 | 0.67 | 46.0 | 4.51e-01 | 89.4% | 64.3% |
| 3981202 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 45.0 | 3.20e-01 | 81.7% | 24.7% |
| 3712624 | 604.12.1.46 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DGF-1_C | 0.66 | 42.0 | 4.71e-01 | 86.5% | 82.5% |
| 5025670 | 4070.1.1.0 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like | 0.65 | 60.0 | 4.94e-01 | 100.0% | 70.0% |
| 3501677 | 5050.1.1.5 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Folate_carrier | 0.65 | 48.0 | 3.74e-01 | 94.2% | 38.5% |
| 3395652 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 40.0 | 3.93e-01 | 81.7% | 57.4% |
| 3580283 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 42.0 | 4.55e-01 | 85.6% | 81.2% |
| 4981323 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.63 | 51.0 | 4.43e-01 | 85.6% | 78.7% |
| 4941690 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.63 | 58.0 | 4.66e-01 | 100.0% | 74.7% |
| 3223682 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 45.0 | 3.70e-01 | 98.1% | 39.5% |
| 3584465 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 47.0 | 4.44e-01 | 98.1% | 66.2% |
| 3229713 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 50.0 | 4.38e-01 | 85.6% | 82.0% |
| 5046491 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.61 | 50.0 | 4.39e-01 | 85.6% | 87.6% |
| 5067364 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.61 | 55.0 | 4.39e-01 | 100.0% | 74.6% |
| 3932388 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 45.0 | 3.59e-01 | 98.1% | 37.7% |
| 5063675 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.60 | 50.0 | 4.20e-01 | 85.6% | 83.1% |
| 5039404 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.60 | 38.0 | 4.33e-01 | 89.4% | 88.0% |
| 3920438 | 150.3.1.4 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IFN-gamma | 0.60 | 48.0 | 4.14e-01 | 91.3% | 56.1% |
| 3862009 | 3755.3.1.293 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH | 0.60 | 49.0 | 4.20e-01 | 86.5% | 83.7% |
| 4941367 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 49.0 | 4.11e-01 | 85.6% | 78.8% |
| 5059077 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.60 | 50.0 | 4.31e-01 | 89.4% | 85.6% |
| 3243589 | 109.4.1.590 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NopRA1 | 0.58 | 46.0 | 2.96e-01 | 83.7% | 23.8% |
| 3586746 | 603.1.1.133 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7799 | 0.58 | 45.0 | 4.29e-01 | 81.7% | 78.3% |
| 3929825 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.56 | 47.0 | 4.44e-01 | 86.5% | 80.8% |
| 3226372 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.56 | 43.0 | 4.35e-01 | 85.6% | 80.0% |
| 4932167 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.55 | 50.0 | 4.57e-01 | 95.2% | 95.4% |
| 3328324 | 611.8.1.1 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne | 0.55 | 41.0 | 3.41e-01 | 79.8% | 53.5% |
| 54358 | 4266.1.1.0 ↗ | alpha bundles › Hyaluronidase domain-like › Hyaluronidase post-catalytic domain-like › Hyaluronidase post-catalytic domain-like | 0.55 | 37.0 | 3.30e-01 | 83.7% | 46.8% |
| 3795777 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.54 | 47.0 | 4.40e-01 | 93.3% | 86.4% |
| 3605877 | 109.4.1.1164 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › zf-MYND | 0.54 | 45.0 | 3.09e-01 | 89.4% | 47.3% |
| 3229018 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.53 | 44.0 | 4.07e-01 | 89.4% | 76.3% |
| 3793666 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 42.0 | 3.31e-01 | 82.7% | 95.7% |
| 3718967 | 109.4.1.648 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CFAP54_N | 0.53 | 43.0 | 2.95e-01 | 86.5% | 35.8% |
| 3658685 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.52 | 44.0 | 4.27e-01 | 89.4% | 86.1% |
| 3473258 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.52 | 43.0 | 3.26e-01 | 89.4% | 43.3% |
| 3958018 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 45.0 | 3.71e-01 | 98.1% | 55.4% |
| 3819222 | 109.4.1.1185 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BTB-POZ_ANK-like | 0.51 | 39.0 | 2.90e-01 | 81.7% | 31.1% |
D5
medium
residues 525-554_687-830
Domain cluster:
rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 112.7 | 2.90e-32 | 82.8% | 26.5% |
| PF00136.27 | DNA_pol_B | 28.9 | 7.20e-07 | 17.2% | 5.7% |
D6
medium
residues 555-620_667-686
Domain cluster:
rep: DNA_polymerase__YP_008052566__Phaeocystis_globosa_virus__251749__D724-746_869-928
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 26.4 | 4.20e-06 | 72.1% | 9.7% |