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3C

Euk-Vir

Human_cosavirus_B

3C__YP_002956114__Human_cosavirus_B__586420

Identity

Accession:
YP_002956114 ↗
Protein ID:
3C
Kingdom:
euk

Quality

82.8 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Picornavirales› Picornaviridae› Cosavirus› Human_cosavirus_B

TaxID: 586420

Cluster

View cluster (62 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 114-317
PDB
Domain cluster: rep: replication_associated_protein__YP_009345107__Amphibola_crenata_associated_bacilladnavirus_1__1941435__D302-478
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00910.29 best RNA_helicase 105.8 2.30e-30 50.0% 100.0%
D2 medium residues 5-102
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.70 62.0 5.70e-01 100.0% 93.8%
2idgA00 1.10.3480.10 Mainly Alpha › Orthogonal Bundle › TorD-like › TorD-like 0.67 55.0 4.68e-01 88.8% 97.5%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.66 54.0 4.77e-01 88.8% 78.3%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 53.0 5.09e-01 89.8% 88.8%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 51.0 4.47e-01 85.7% 58.4%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 47.0 3.89e-01 77.6% 85.6%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 48.0 5.12e-01 80.6% 91.9%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 54.0 4.33e-01 100.0% 72.4%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 46.0 3.97e-01 77.6% 86.0%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.60 43.0 4.11e-01 73.5% 66.7%
4ys0A02 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.60 44.0 3.68e-01 77.6% 97.1%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 48.0 3.94e-01 89.8% 92.9%
4od4A01 1.10.357.140 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › UbiA prenyltransferase 0.57 44.0 3.86e-01 85.7% 89.7%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 47.0 4.25e-01 90.8% 85.1%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 41.0 3.66e-01 79.6% 66.9%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.54 44.0 4.04e-01 88.8% 84.0%
4x28A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 42.0 3.65e-01 84.7% 74.5%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.54 38.0 3.40e-01 73.5% 75.5%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.54 43.0 4.23e-01 88.8% 98.1%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 42.0 3.65e-01 87.8% 79.6%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 38.0 3.59e-01 100.0% 63.3%
1n5uA04 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.51 39.0 4.13e-01 85.7% 94.2%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 38.0 3.76e-01 100.0% 73.3%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4934787 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.70 57.0 4.48e-01 89.8% 87.6%
3497911 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.67 55.0 4.95e-01 89.8% 86.7%
3495283 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 53.0 4.82e-01 89.8% 80.7%
3715982 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 45.0 3.07e-01 75.5% 33.9%
3867850 607.1.1.4 ↗ alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PF31020 0.62 50.0 4.66e-01 85.7% 82.5%
3748471 4953.1.1.33 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › PF31020 0.62 49.0 4.63e-01 85.7% 82.5%
3315159 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.62 53.0 4.57e-01 96.9% 76.2%
5021415 3579.1.1.33 ↗ extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PsiE 0.61 45.0 4.18e-01 77.6% 68.8%
3246096 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.61 51.0 3.39e-01 88.8% 28.4%
3363132 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 43.0 3.55e-01 75.5% 52.4%
3969620 5069.1.2.2 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › DUF3483 0.60 49.0 4.00e-01 90.8% 72.8%
3957075 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 47.0 4.14e-01 85.7% 83.3%
3468530 611.2.1.2 ↗ alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N 0.59 42.0 3.99e-01 73.5% 66.1%
3306743 192.29.1.101 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Rx_N 0.59 43.0 3.93e-01 77.6% 79.3%
5047069 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.59 43.0 3.31e-01 77.6% 43.5%
3286925 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.57 40.0 3.79e-01 73.5% 70.0%
4944283 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 46.0 4.12e-01 88.8% 90.7%
4963637 5069.1.2.6 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › PF26448 0.56 45.0 3.85e-01 88.8% 99.4%
3855328 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.56 43.0 4.39e-01 82.7% 86.3%
5035275 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.55 40.0 3.98e-01 78.6% 77.1%
3696873 109.4.1.163 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N 0.55 42.0 2.56e-01 82.7% 15.5%
3431479 109.4.1.1908 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long, E_motif 0.53 41.0 2.98e-01 100.0% 29.1%
3757869 4006.1.1.0 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.53 41.0 4.14e-01 82.7% 87.4%
3219809 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.53 40.0 3.87e-01 79.6% 82.7%
3624439 611.4.1.0 ↗ alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like 0.52 37.0 3.10e-01 72.4% 47.0%
5050969 109.4.1.192 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.52 41.0 3.28e-01 100.0% 41.5%
3462555 109.4.1.1272 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif 0.51 38.0 3.21e-01 100.0% 44.4%
3364252 109.4.1.1331 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_long, E_motif 0.50 39.0 2.76e-01 100.0% 25.6%
3656431 109.4.1.1269 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, E_motif 0.50 39.0 2.59e-01 100.0% 18.7%
3306714 109.4.1.1272 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif 0.50 38.0 2.61e-01 100.0% 21.9%
3925416 109.4.1.1361 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_CAND1 0.50 39.0 3.09e-01 86.7% 61.8%
3648078 109.4.1.1254 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.50 37.0 2.72e-01 100.0% 28.0%