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3D
Euk-VirEnterovirus_A
3D__NP_740536__Enterovirus_A__138948
Identity
- Accession:
- NP_740536 ↗
- Protein ID:
- 3D
- Kingdom:
- euk
Quality
95.1
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Picornavirales›
Picornaviridae›
Enterovirus›
Enterovirus_A
TaxID: 138948
Cluster
View cluster (450 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 373-460
Domain cluster:
rep: putative_3D_RNA-dependent_RNA_polymerase__YP_009553719__tremovirus_B1__2058161__D405-481
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ra6A03 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.99 | 93.0 | 9.39e-01 | 96.6% | 97.7% |
| 3nkyA03 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.93 | 63.0 | 6.88e-01 | 76.1% | 83.6% |
| 2ckwA04 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.80 | 73.0 | 6.86e-01 | 100.0% | 96.3% |
| 1khvA05 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.80 | 70.0 | 6.82e-01 | 95.5% | 97.9% |
| 3h5xA04 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.72 | 65.0 | 6.38e-01 | 100.0% | 98.9% |
| 1ldjA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.64 | 45.0 | 4.01e-01 | 72.7% | 95.2% |
| 4ip8A00 | 1.10.132.110 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein | 0.62 | 51.0 | 4.81e-01 | 88.6% | 81.9% |
| 2c12A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.61 | 44.0 | 3.94e-01 | 76.1% | 82.7% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 49.0 | 3.95e-01 | 100.0% | 80.3% |
| 1elkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 46.0 | 3.87e-01 | 88.6% | 73.2% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 41.0 | 3.62e-01 | 78.4% | 74.1% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.56 | 45.0 | 4.03e-01 | 89.8% | 67.7% |
| 3cqyB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 40.0 | 3.19e-01 | 77.3% | 80.4% |
| 4ksaA02 | 1.20.140.90 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Malonyl-CoA decarboxylase, oligemerization domain | 0.54 | 45.0 | 3.96e-01 | 94.3% | 84.7% |
| 3rkoF01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.53 | 34.0 | 2.82e-01 | 86.4% | 35.6% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 40.0 | 3.72e-01 | 87.5% | 93.8% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 42.0 | 3.49e-01 | 97.7% | 83.8% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1519288 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 1.00 | 97.0 | 9.35e-01 | 100.0% | 90.7% |
| 2541767 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.92 | 89.0 | 8.52e-01 | 100.0% | 92.8% |
| 3092371 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.82 | 75.0 | 7.16e-01 | 100.0% | 92.2% |
| 3779 | 4967.1.1.2 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_1 | 0.81 | 75.0 | 6.96e-01 | 100.0% | 92.5% |
| 2721357 | 604.39.1.5 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt | 0.69 | 51.0 | 3.85e-01 | 77.3% | 56.5% |
| 4996381 | 3352.1.1.2 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 | 0.66 | 55.0 | 3.61e-01 | 93.2% | 55.9% |
| 3785430 | 3352.1.1.6 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Glyco_transf_22 | 0.64 | 56.0 | 3.67e-01 | 100.0% | 32.8% |
| 3541264 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.63 | 56.0 | 3.89e-01 | 98.9% | 54.1% |
| 3920949 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.63 | 56.0 | 4.43e-01 | 98.9% | 83.3% |
| 3572779 | 3855.1.1.1 ↗ | alpha arrays › Serum amyloid A-1 protein › Serum amyloid A-1 protein › Serum amyloid A-1 protein › SAA | 0.61 | 50.0 | 4.63e-01 | 88.6% | 85.5% |
| 3259266 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.59 | 48.0 | 4.21e-01 | 92.0% | 64.3% |
| 4003112 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 50.0 | 3.73e-01 | 94.3% | 46.7% |
| 3700350 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 42.0 | 3.82e-01 | 95.5% | 92.0% |
D2
medium
residues 1-16_240-289
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.69 | 37.0 | 3.34e-01 | 74.2% | 38.0% |
| 2ahmG01 | 6.10.250.2820 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.59 | 35.0 | 3.14e-01 | 93.9% | 39.4% |
| 2q14A02 | 1.20.1250.30 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 39.0 | 2.91e-01 | 98.5% | 27.7% |
| 2amyA02 | 3.30.1240.20 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › Eukaryotic phosphomannomutase, cap domain | 0.57 | 34.0 | 2.94e-01 | 97.0% | 38.2% |
| 4hkqA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.53 | 36.0 | 2.78e-01 | 81.8% | 31.9% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1173784 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.97 | 93.0 | 5.56e-01 | 100.0% | 78.3% |
| None | — | 0.92 | 88.0 | 5.27e-01 | 100.0% | 78.4% | |
| 5367 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.85 | 79.0 | 4.76e-01 | 100.0% | 78.8% |
| 4011754 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.64 | 35.0 | 3.11e-01 | 97.0% | 35.8% |
| 3594603 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.57 | 34.0 | 2.96e-01 | 97.0% | 39.0% |
| 5053743 | 328.6.1.1 ↗ | a+b two layers › IF3-like › EPT/RTPC-like › EPT/RTPC-like › EPSP_synthase | 0.54 | 30.0 | 2.13e-01 | 93.9% | 15.5% |
| 4361292 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.54 | 42.0 | 2.56e-01 | 86.4% | 26.6% |
| 4024117 | 101.1.2.366 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF3161 | 0.51 | 36.0 | 3.28e-01 | 90.9% | 54.4% |
| None | — | 0.51 | 42.0 | 2.71e-01 | 92.4% | 41.9% |
D3
medium
residues 17-67_159-183
Domain cluster:
rep: 3D__YP_003853309__Oscivirus_A1__871700__D16-60_161-177
D4
medium
residues 68-89_208-239_290-372
Domain cluster:
rep: RNA_dependent_RNA_polymerase__YP_529897__Newbury_agent_1__331642__D58-79_192-241_281-399
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02123.22 best | RdRP_4 | 29.5 | 5.30e-07 | 89.0% | 14.4% |
| PF00680.26 | RdRP_1 | 43.0 | 3.80e-11 | 86.9% | 21.8% |
D5
medium
residues 90-158_184-207
Domain cluster:
rep: 3D__YP_009179377__sicinivirus_A1__2773315__D75-149_180-201