3D

Euk-Vir

Cosavirus_D

3D__YP_002956129__Cosavirus_D__2003650

Identity

96.2 mean pLDDT

Orthornavirae› Pisuviricota› Pisoniviricetes› Picornavirales› Picornaviridae› Cosavirus› Cosavirus_D

TaxID: 2003650

View cluster (450 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 395-460

PDB

Domain cluster: rep: putative_3D_RNA-dependent_RNA_polymerase__YP_009553719__tremovirus_B1__2058161__D405-481

D2 medium residues 24-59_92-182

PDB

Domain cluster: rep: hypothetical_protein_2__YP_009337735__Wenling_sobemo-like_virus_2__1923541__D4-91_185-200

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00680.26 best	RdRP_1	49.5	3.80e-13	81.1%	22.0%

D3 medium residues 60-91_204-244_296-394

PDB

Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_529897__Newbury_agent_1__331642__D58-79_192-241_281-399

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00680.26 best	RdRP_1	49.9	3.00e-13	58.7%	23.3%
PF02123.22	RdRP_4	27.7	1.80e-06	46.5%	14.2%

D4 medium residues 183-203_245-295

PDB

Domain cluster: representative

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2r7rA05	1.10.357.80	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.75	66.0	4.94e-01	98.6%	69.9%
1yirA00	3.20.140.10	Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase	0.53	40.0	2.57e-01	84.7%	95.1%
8d3mA02	1.20.120.920	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain	0.51	35.0	2.49e-01	70.8%	23.7%
6l3tA01	1.20.1440.80	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Gap junction channel protein cysteine-rich domain	0.51	40.0	3.04e-01	90.3%	86.4%
2g29A01	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.51	38.0	2.68e-01	83.3%	67.3%
2mkhA02	3.30.70.330	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain	0.50	33.0	3.07e-01	91.7%	50.5%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5367	304.48.1.8 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1	0.95	91.0	5.49e-01	100.0%	29.9%
3458015	109.20.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › Coatomer subunit alpha C-terminal domain › Coatomer subunit alpha C-terminal domain › COPI_C	0.53	36.0	2.54e-01	70.8%	40.8%
4016275	109.4.1.2191 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, TPR_14, TPR_19, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N, HAT_PRP39_C	0.53	37.0	2.13e-01	73.6%	13.9%
4019671	109.4.1.64 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GET4	0.52	38.0	2.57e-01	79.2%	35.1%
4145802	3236.1.1.5 ↗	alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_antiport_1	0.52	37.0	2.37e-01	76.4%	70.1%
4521030	3236.1.1.5 ↗	alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_antiport_1	0.51	41.0	2.66e-01	93.1%	22.8%
4941594	213.1.1.17 ↗	a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › DUF1122	0.51	35.0	2.57e-01	72.2%	60.9%
3287189	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	38.0	2.31e-01	83.3%	55.9%