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5-3_exoribonuclease

Euk-Vir

Pithovirus_sibericum

5-3_exoribonuclease__YP_009001338__Pithovirus_sibericum__1450746

Identity

Accession:: YP_009001338 ↗
Protein ID:: 5-3_exoribonuclease
Kingdom:: euk

Quality

70.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (15 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 25-42_67-105_132-236_503-535

PDB

Domain cluster: rep: Hypothetical_protein_SPPV_50__NP_659626__Sheeppox_virus__10266__D1-82_143-236

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03159.25 best	XRN_N	71.5	1.10e-19	44.6%	39.4%

D2 medium residues 43-66_106-131

PDB

Domain cluster: representative

D3 medium residues 237-336

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF17846.7 best	XRN_M	43.2	3.90e-11	99.0%	20.0%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2g8lB01	1.10.8.380	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1	0.63	39.0	4.62e-01	74.0%	94.0%
1bqbA02	1.10.390.10	Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2	0.54	38.0	3.43e-01	73.0%	91.0%
4i9oA00	1.10.246.20	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain	0.53	37.0	4.07e-01	73.0%	100.0%
4nv0A02	1.10.150.340	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain	0.51	35.0	3.75e-01	80.0%	85.4%
3u9jA00	1.20.120.520	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like	0.50	39.0	3.48e-01	87.0%	67.5%

ECOD (10)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3684346	3279.1.1.1 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › XRN_M	0.83	74.0	5.02e-01	94.0%	83.8%
3595158	3279.1.1.0 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases	0.81	73.0	5.14e-01	96.0%	82.5%
3608857	3279.1.1.1 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › XRN_M	0.80	74.0	5.21e-01	100.0%	39.7%
3340442	3279.1.1.1 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › XRN_M	0.76	70.0	5.51e-01	97.0%	59.5%
4027649	3279.1.1.1 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › XRN_M	0.75	67.0	4.72e-01	94.0%	79.6%
3600228	3279.1.1.0 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases	0.75	67.0	4.66e-01	95.0%	86.2%
4017552	3279.1.1.1 ↗	alpha arrays › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › Helical domain in 5'->3' exoribonucleases › XRN_M	0.68	63.0	4.49e-01	97.0%	48.8%
3994879	102.2.1.0 ↗	alpha arrays › HhH/H2TH › H2TH › H2TH	0.56	40.0	4.17e-01	95.0%	81.1%
3988293	5050.1.1.0 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter	0.52	40.0	3.33e-01	84.0%	66.8%
3366160	102.2.1.0 ↗	alpha arrays › HhH/H2TH › H2TH › H2TH	0.51	40.0	3.98e-01	93.0%	81.0%

D4 medium residues 337-444

PDB

D5 medium residues 448-481

PDB