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5H_04062016_scaffold_1_prodigal-single.1__X__X__00018
Bact-Vir5H_04062016_scaffold_1_prodigal-single.1__X__X__00018
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-61_129-139
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09988.16 best | DUF2227 | 48.5 | 1.40e-12 | 91.7% | 36.1% |
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ex3B02 | 1.20.1270.230 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › DNA terminal protein Gp3, priming domain | 0.72 | 46.0 | 4.43e-01 | 91.7% | 58.0% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.67 | 45.0 | 4.53e-01 | 80.6% | 69.0% |
| 1h3lB00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.67 | 51.0 | 4.97e-01 | 100.0% | 75.6% |
| 3w8hB00 | 1.10.12.70 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › | 0.67 | 49.0 | 5.10e-01 | 97.2% | 86.4% |
| 5b1oA00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.65 | 44.0 | 4.65e-01 | 83.3% | 78.5% |
| 5lb3B02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.64 | 47.0 | 3.26e-01 | 83.3% | 24.1% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.64 | 45.0 | 4.41e-01 | 80.6% | 68.8% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 42.0 | 4.24e-01 | 80.6% | 67.1% |
| 2guzB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.63 | 41.0 | 4.27e-01 | 77.8% | 72.3% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.62 | 53.0 | 4.68e-01 | 97.2% | 95.5% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 46.0 | 4.47e-01 | 80.6% | 100.0% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.60 | 39.0 | 3.98e-01 | 81.9% | 68.6% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.59 | 42.0 | 4.42e-01 | 94.4% | 84.8% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.59 | 43.0 | 4.18e-01 | 83.3% | 70.9% |
| 2y4tA02 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.58 | 39.0 | 4.31e-01 | 83.3% | 94.2% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.57 | 43.0 | 2.87e-01 | 80.6% | 70.6% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.57 | 40.0 | 2.75e-01 | 81.9% | 18.3% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 41.0 | 3.94e-01 | 80.6% | 69.0% |
| 2qsaA00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 43.0 | 3.92e-01 | 84.7% | 76.2% |
| 4hteA03 | 1.10.167.30 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › | 0.56 | 36.0 | 3.56e-01 | 76.4% | 60.0% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.56 | 39.0 | 4.17e-01 | 84.7% | 90.2% |
| 1qrvA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.55 | 35.0 | 3.57e-01 | 93.1% | 64.4% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.55 | 40.0 | 3.90e-01 | 79.2% | 88.9% |
| 2yukA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.55 | 38.0 | 3.59e-01 | 73.6% | 96.7% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 42.0 | 3.72e-01 | 84.7% | 58.7% |
| 3i2fA02 | 1.10.3020.10 | Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) | 0.53 | 47.0 | 4.31e-01 | 100.0% | 77.9% |
| 3hgtA00 | 3.40.50.12360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 47.0 | 3.14e-01 | 100.0% | 68.9% |
| 2z16B01 | 1.20.91.10 | Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Influenza matrix M1, N-terminal subdomain 1 | 0.53 | 47.0 | 4.57e-01 | 97.2% | 91.0% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.52 | 43.0 | 3.66e-01 | 91.7% | 60.0% |
| 4lqxA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 45.0 | 3.04e-01 | 100.0% | 63.0% |
| 4biuE01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.52 | 40.0 | 3.68e-01 | 84.7% | 67.3% |
| 1lm7A00 | 3.90.1290.10 | Alpha Beta › Alpha-Beta Complex › beta-hairpin-alpha-hairpin repeat › Plakin repeat | 0.51 | 44.0 | 3.11e-01 | 98.6% | 75.2% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3686609 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.76 | 56.0 | 5.20e-01 | 84.7% | 62.2% |
| 4318142 | 230.3.1.1 ↗ | a+b two layers › T-fold › Elongation factor Ts (EF-Ts), dimerisation domain › Elongation factor Ts (EF-Ts), dimerisation domain › EF_TS | 0.74 | 51.0 | 4.07e-01 | 100.0% | 36.4% |
| 5047182 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.71 | 50.0 | 5.28e-01 | 75.0% | 84.6% |
| 3477975 | 7023.1.1.0 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein | 0.69 | 54.0 | 4.58e-01 | 83.3% | 80.0% |
| 4998576 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.69 | 54.0 | 5.38e-01 | 84.7% | 94.7% |
| 3588332 | 5069.1.1.23 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF2798 | 0.69 | 51.0 | 4.15e-01 | 100.0% | 41.4% |
| 4981035 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.68 | 49.0 | 5.09e-01 | 75.0% | 86.2% |
| 4930860 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.68 | 48.0 | 4.52e-01 | 75.0% | 62.2% |
| 3656530 | 143.1.1.0 ↗ | alpha arrays › PABP domain-like › PABC(PABP) domain › PABC(PABP) domain | 0.68 | 46.0 | 4.62e-01 | 98.6% | 68.0% |
| 4940089 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.68 | 50.0 | 4.37e-01 | 79.2% | 57.3% |
| 4297580 | 3625.1.1.0 ↗ | alpha bundles › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain | 0.67 | 43.0 | 4.44e-01 | 86.1% | 67.1% |
| 4928737 | 592.2.1.0 ↗ | alpha arrays › PWI domain-like › YugE-like › YugE-like | 0.65 | 49.0 | 4.52e-01 | 81.9% | 61.1% |
| 4980624 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.65 | 50.0 | 4.76e-01 | 83.3% | 82.4% |
| 3492091 | 5063.1.1.16 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Romo1 | 0.63 | 48.0 | 5.04e-01 | 100.0% | 92.3% |
| 4203104 | 3560.1.1.7 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med10 | 0.63 | 42.0 | 3.37e-01 | 80.6% | 33.8% |
| 3960310 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.63 | 42.0 | 4.28e-01 | 94.4% | 71.4% |
| 5005176 | 604.15.1.0 ↗ | alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like | 0.62 | 39.0 | 4.15e-01 | 76.4% | 70.8% |
| 3607406 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.61 | 52.0 | 5.08e-01 | 94.4% | 90.0% |
| 3283355 | 150.5.1.51 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100_2 | 0.61 | 44.0 | 4.18e-01 | 76.4% | 65.9% |
| 4932741 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.60 | 44.0 | 4.43e-01 | 87.5% | 76.0% |
| 5060491 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 42.0 | 3.65e-01 | 79.2% | 45.0% |
| 4149779 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.60 | 53.0 | 4.64e-01 | 100.0% | 69.1% |
| 4950718 | 246.3.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos | 0.59 | 53.0 | 3.45e-01 | 100.0% | 44.9% |
| 4665954 | 547.1.1.0 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain | 0.59 | 53.0 | 5.14e-01 | 100.0% | 93.8% |
| 5040824 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.59 | 51.0 | 4.00e-01 | 97.2% | 46.1% |
| 5041296 | 2003.1.1.7 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ELFV_dehydrog | 0.58 | 51.0 | 3.70e-01 | 98.6% | 37.0% |
| 3562783 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.55 | 41.0 | 3.49e-01 | 79.2% | 51.3% |
| 3831337 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.55 | 45.0 | 3.47e-01 | 93.1% | 65.7% |
| 4031440 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.52 | 47.0 | 4.46e-01 | 100.0% | 92.9% |
| 3993340 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.52 | 41.0 | 3.58e-01 | 86.1% | 70.9% |
| 5001990 | 4044.1.1.1 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane | 0.51 | 45.0 | 3.78e-01 | 98.6% | 78.4% |
D2
medium
residues 62-128
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09988.16 best | DUF2227 | 55.4 | 1.10e-14 | 88.1% | 28.4% |