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5H_04062016_scaffold_1_prodigal-single.1__X__X__00248
Bact-Vir5H_04062016_scaffold_1_prodigal-single.1__X__X__00248
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 201-325
Domain cluster:
rep: MN698246.1__QGZ18180.1__HTVC112P_gp03__00003__D120-243
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7mi4A01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.81 | 65.0 | 5.46e-01 | 100.0% | 53.3% |
| 3l0aA00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.76 | 66.0 | 5.02e-01 | 98.4% | 42.9% |
| 4ic1D00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.76 | 60.0 | 4.95e-01 | 100.0% | 49.5% |
| 8d3mI01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.74 | 64.0 | 5.30e-01 | 100.0% | 54.6% |
| 3h4rA00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.74 | 64.0 | 5.20e-01 | 99.2% | 52.1% |
| 1ob8A00 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.73 | 47.0 | 4.87e-01 | 94.4% | 68.1% |
| 3fovA00 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.73 | 51.0 | 5.54e-01 | 92.8% | 87.3% |
| 5zyuA01 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.72 | 62.0 | 5.20e-01 | 100.0% | 56.2% |
| 3sm4A00 | 3.90.320.10 | Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › | 0.69 | 56.0 | 4.55e-01 | 99.2% | 47.1% |
| 1y88A01 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.69 | 47.0 | 4.74e-01 | 92.0% | 69.6% |
| 1xmxA02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.68 | 48.0 | 4.50e-01 | 90.4% | 60.4% |
| 4hlbA00 | 3.30.70.2960 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 46.0 | 5.18e-01 | 90.4% | 97.9% |
| 2cxcA01 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.62 | 34.0 | 4.30e-01 | 74.4% | 95.7% |
| 5mv0A01 | 3.30.70.2640 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Arenavirus RNA polymerase | 0.61 | 42.0 | 4.92e-01 | 77.6% | 98.9% |
| 6p4wB01 | 3.40.91.30 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.61 | 42.0 | 4.46e-01 | 84.8% | 79.8% |
| 2xxpA02 | 3.40.630.190 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein | 0.61 | 49.0 | 3.80e-01 | 85.6% | 91.8% |
| 1d02B00 | 3.40.580.10 | Alpha Beta › 3-Layer(aba) Sandwich › ECO RI Endonuclease; Chain A › Eco RI Endonuclease, subunit A | 0.60 | 48.0 | 4.07e-01 | 84.8% | 75.5% |
| 4esjA01 | 3.40.210.30 | Alpha Beta › 3-Layer(aba) Sandwich › PvuII Endonuclease; Chain A › Dam replacing family, catalytic PD-(D/E)XK domain | 0.58 | 37.0 | 3.48e-01 | 95.2% | 50.6% |
| 4g6uA02 | 3.40.1350.110 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.58 | 45.0 | 4.42e-01 | 92.8% | 75.4% |
| 4ftfA00 | 3.30.300.250 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.58 | 42.0 | 4.46e-01 | 95.2% | 87.2% |
| 2w3qA02 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.55 | 47.0 | 4.32e-01 | 92.0% | 97.6% |
| 4oa3A00 | 3.10.310.50 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › | 0.55 | 33.0 | 3.23e-01 | 91.2% | 51.1% |
| 1r5tA00 | 3.40.140.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 | 0.54 | 40.0 | 3.92e-01 | 98.4% | 70.2% |
| 3cskA03 | 3.30.70.2600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 32.0 | 3.88e-01 | 76.8% | 96.1% |
| 3e38B01 | 3.20.20.140 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases | 0.54 | 38.0 | 3.05e-01 | 88.8% | 37.1% |
| 2kqrA01 | 3.30.1910.20 | Alpha Beta › 2-Layer Sandwich › so0334 like fold › asparaginyl-tRNA synthetase, N-terminal domain | 0.53 | 32.0 | 3.95e-01 | 81.6% | 100.0% |
| 4da2A02 | 3.40.1350.60 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.52 | 40.0 | 3.84e-01 | 92.0% | 68.4% |
| 5fusA01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.51 | 42.0 | 3.53e-01 | 93.6% | 50.9% |
| 1ekjA00 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.51 | 43.0 | 3.63e-01 | 92.0% | 81.4% |
| 8dqoB01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.50 | 36.0 | 3.20e-01 | 75.2% | 79.3% |
ECOD (89)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3964058 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.88 | 61.0 | 5.84e-01 | 92.8% | 62.9% |
| 4929251 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.85 | 67.0 | 5.67e-01 | 100.0% | 53.7% |
| 5066595 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.85 | 65.0 | 5.47e-01 | 100.0% | 51.0% |
| 5005960 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.84 | 65.0 | 5.65e-01 | 100.0% | 54.9% |
| 4046812 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.84 | 63.0 | 5.41e-01 | 100.0% | 51.6% |
| 4947545 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.83 | 65.0 | 5.54e-01 | 100.0% | 53.2% |
| 5042023 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.83 | 65.0 | 5.52e-01 | 100.0% | 53.2% |
| 2798007 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.81 | 65.0 | 5.43e-01 | 100.0% | 52.5% |
| 3614493 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.81 | 76.0 | 5.60e-01 | 100.0% | 55.7% |
| 4346470 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.80 | 69.0 | 5.17e-01 | 97.6% | 40.4% |
| 3253903 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.80 | 64.0 | 5.17e-01 | 100.0% | 47.3% |
| 3945875 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.80 | 66.0 | 6.37e-01 | 100.0% | 77.9% |
| 3226148 | 2008.1.1.29 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Dna2 | 0.79 | 63.0 | 4.69e-01 | 100.0% | 36.1% |
| 4953680 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.79 | 64.0 | 4.92e-01 | 100.0% | 40.9% |
| 4314348 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.79 | 64.0 | 5.50e-01 | 100.0% | 56.3% |
| 4955135 | 2008.1.1.159 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Csa1 | 0.78 | 63.0 | 4.57e-01 | 100.0% | 33.9% |
| 4950447 | 2008.1.1.87 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C | 0.77 | 54.0 | 5.02e-01 | 90.4% | 58.4% |
| 3969697 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.76 | 65.0 | 6.01e-01 | 100.0% | 72.3% |
| 3221910 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.76 | 69.0 | 5.27e-01 | 100.0% | 45.8% |
| 4242672 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.76 | 55.0 | 4.62e-01 | 100.0% | 46.5% |
| 4536530 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.75 | 64.0 | 4.97e-01 | 88.8% | 46.1% |
| 5044119 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.75 | 52.0 | 5.23e-01 | 91.2% | 70.4% |
| 4290285 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.75 | 62.0 | 4.92e-01 | 100.0% | 44.9% |
| 4942551 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.74 | 59.0 | 4.82e-01 | 100.0% | 47.7% |
| 5079331 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.73 | 49.0 | 4.96e-01 | 89.6% | 68.0% |
| 4876381 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.73 | 62.0 | 5.80e-01 | 100.0% | 73.9% |
| 3629495 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.73 | 64.0 | 4.79e-01 | 100.0% | 40.3% |
| 5051988 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.73 | 47.0 | 4.84e-01 | 92.0% | 68.3% |
| 3480310 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.72 | 63.0 | 5.09e-01 | 100.0% | 51.1% |
| 5001925 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.72 | 52.0 | 4.89e-01 | 89.6% | 62.0% |
| 5080539 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.71 | 47.0 | 4.42e-01 | 91.2% | 54.9% |
| 4943737 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.71 | 63.0 | 5.75e-01 | 100.0% | 73.1% |
| 5061506 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.71 | 47.0 | 4.88e-01 | 84.8% | 72.2% |
| 4060516 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.71 | 53.0 | 5.53e-01 | 92.8% | 84.3% |
| 4403112 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.71 | 52.0 | 5.28e-01 | 91.2% | 77.2% |
| 5021928 | 2008.1.1.87 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C | 0.70 | 50.0 | 4.61e-01 | 92.0% | 57.5% |
| 4022097 | 2008.1.1.97 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 | 0.70 | 66.0 | 4.97e-01 | 100.0% | 51.1% |
| 2439587 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.70 | 60.0 | 4.82e-01 | 100.0% | 48.5% |
| 4103907 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.70 | 66.0 | 4.56e-01 | 100.0% | 49.3% |
| 4951113 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.70 | 64.0 | 4.96e-01 | 100.0% | 48.4% |
| 4599083 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.70 | 65.0 | 4.49e-01 | 100.0% | 48.5% |
| 5018195 | 2008.1.1.87 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C | 0.70 | 50.0 | 4.79e-01 | 92.0% | 64.1% |
| 4010728 | 2008.1.1.87 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › YhcG_C | 0.70 | 50.0 | 4.86e-01 | 92.0% | 68.1% |
| 4120139 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.69 | 65.0 | 4.45e-01 | 100.0% | 52.2% |
| 3954245 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.68 | 53.0 | 5.43e-01 | 88.8% | 84.7% |
| 3813800 | 2008.1.1.107 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD | 0.68 | 57.0 | 5.34e-01 | 88.0% | 76.7% |
| 4670340 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.68 | 51.0 | 5.31e-01 | 92.8% | 85.1% |
| 1030945 | 2008.1.1.34 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Card1_endonuc | 0.68 | 48.0 | 4.67e-01 | 91.2% | 66.7% |
| 4002824 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.68 | 63.0 | 4.73e-01 | 100.0% | 44.4% |
| 5024521 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.68 | 64.0 | 4.45e-01 | 100.0% | 35.9% |
| 3716928 | 2008.1.1.107 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD | 0.68 | 56.0 | 4.77e-01 | 86.4% | 65.6% |
| 5044802 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.68 | 53.0 | 4.38e-01 | 89.6% | 48.6% |
| 4939656 | 2008.1.1.102 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF1829 | 0.67 | 47.0 | 4.77e-01 | 92.0% | 72.0% |
| 4958436 | 2008.1.1.217 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UvrD-helicase | 0.67 | 62.0 | 3.57e-01 | 100.0% | 11.4% |
| 3338602 | 2008.1.1.107 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD | 0.67 | 56.0 | 4.87e-01 | 88.0% | 63.2% |
| 4991381 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.67 | 49.0 | 5.08e-01 | 84.8% | 79.8% |
| 3931362 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.67 | 55.0 | 4.16e-01 | 87.2% | 47.0% |
| 4534629 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.67 | 52.0 | 5.31e-01 | 94.4% | 85.0% |
| 5014788 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.66 | 49.0 | 5.09e-01 | 84.0% | 82.6% |
| 3726411 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.66 | 48.0 | 4.16e-01 | 92.0% | 49.5% |
| 3733745 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.66 | 50.0 | 4.23e-01 | 93.6% | 49.5% |
| 4459239 | 3585.1.1.0 ↗ | a+b two layers › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain › DNA polymerase III C-terminal domain | 0.65 | 31.0 | 3.81e-01 | 71.2% | 70.0% |
| 3937662 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.64 | 53.0 | 4.27e-01 | 87.2% | 48.3% |
| 4648357 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 57.0 | 3.34e-01 | 100.0% | 17.3% |
| 4950271 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.64 | 54.0 | 4.72e-01 | 89.6% | 68.3% |
| 221616 | 327.7.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › DUF6981 | 0.63 | 46.0 | 5.18e-01 | 90.4% | 97.9% |
| 4072060 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.63 | 56.0 | 3.95e-01 | 100.0% | 49.6% |
| 3262617 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.63 | 44.0 | 4.70e-01 | 79.2% | 82.7% |
| 4967107 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.63 | 53.0 | 4.81e-01 | 90.4% | 81.8% |
| 5078220 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.62 | 57.0 | 4.66e-01 | 96.8% | 88.8% |
| 4998517 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.62 | 53.0 | 5.03e-01 | 92.0% | 77.7% |
| 3603419 | 2008.1.1.212 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27326 | 0.62 | 52.0 | 4.53e-01 | 88.8% | 71.1% |
| 5009814 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.61 | 51.0 | 5.01e-01 | 89.6% | 85.2% |
| 5013275 | 2008.1.1.212 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27326 | 0.61 | 51.0 | 4.33e-01 | 88.8% | 72.3% |
| 4931728 | 2008.1.1.212 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27326 | 0.60 | 50.0 | 4.49e-01 | 88.8% | 71.2% |
| 4313486 | 2008.1.1.6 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › UPF0102 | 0.59 | 48.0 | 4.56e-01 | 86.4% | 86.9% |
| 4968793 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.59 | 49.0 | 4.37e-01 | 92.0% | 64.0% |
| 1007200 | 3105.1.1.1 ↗ | a+b three layers › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › TPM_phosphatase | 0.58 | 33.0 | 3.20e-01 | 88.8% | 46.9% |
| 3604185 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.56 | 51.0 | 4.33e-01 | 99.2% | 76.1% |
| 4014350 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.56 | 51.0 | 3.72e-01 | 100.0% | 73.9% |
| 5014475 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.55 | 46.0 | 4.39e-01 | 88.0% | 75.9% |
| 3166390 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.54 | 47.0 | 4.37e-01 | 92.8% | 85.2% |
| 4260603 | 2008.1.1.11 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SfsA | 0.54 | 42.0 | 3.91e-01 | 92.0% | 65.0% |
| 5073860 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.53 | 41.0 | 4.03e-01 | 90.4% | 74.1% |
| 5002931 | 2008.1.1.11 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SfsA | 0.53 | 41.0 | 3.88e-01 | 92.0% | 67.5% |
| 3600130 | 246.3.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos | 0.53 | 43.0 | 3.21e-01 | 87.2% | 87.2% |
| 4339598 | 2008.1.1.11 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SfsA | 0.53 | 41.0 | 3.91e-01 | 92.0% | 70.0% |
| 5001440 | 2008.1.1.11 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › SfsA | 0.52 | 40.0 | 3.70e-01 | 92.0% | 63.0% |
| 3227080 | 2006.1.6.33 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_4 | 0.52 | 32.0 | 2.76e-01 | 91.2% | 37.0% |
D2
medium
residues 37-89
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4msxA02 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.71 | 56.0 | 3.43e-01 | 84.9% | 80.1% |
| 5chtB00 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.70 | 54.0 | 3.35e-01 | 84.9% | 84.0% |
| 1rwiA00 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.69 | 57.0 | 3.65e-01 | 92.5% | 46.9% |
| 3ifvC00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.69 | 47.0 | 3.06e-01 | 71.7% | 47.5% |
| 1ujrA01 | 3.30.720.50 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › | 0.69 | 50.0 | 4.32e-01 | 79.2% | 49.4% |
| 1k3sA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.69 | 49.0 | 3.84e-01 | 75.5% | 68.5% |
| 4qa8A00 | 2.50.20.20 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › | 0.68 | 49.0 | 3.27e-01 | 77.4% | 36.2% |
| 2bs6A01 | 2.40.128.190 | Mainly Beta › Beta Barrel › Lipocalin › | 0.68 | 48.0 | 4.14e-01 | 75.5% | 96.4% |
| 4ba0A01 | 2.60.40.1760 | Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) | 0.67 | 53.0 | 3.59e-01 | 94.3% | 23.1% |
| 7sz2A01 | 3.30.720.50 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › | 0.67 | 47.0 | 3.98e-01 | 75.5% | 44.6% |
| 6o15A02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.67 | 53.0 | 3.48e-01 | 88.7% | 57.1% |
| 8gq6A01 | 2.120.10.80 | Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller | 0.65 | 54.0 | 3.37e-01 | 92.5% | 42.4% |
| 2dy1A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.65 | 51.0 | 3.26e-01 | 86.8% | 24.4% |
| 2dk6A01 | 3.30.720.50 | Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › | 0.65 | 47.0 | 3.92e-01 | 79.2% | 43.6% |
| 3cwxA00 | 3.40.1420.20 | Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › Pathogenicity island component CagD | 0.65 | 52.0 | 4.03e-01 | 90.6% | 68.8% |
| 3fvcA03 | 2.30.29.100 | Mainly Beta › Roll › PH-domain like › | 0.65 | 44.0 | 3.50e-01 | 71.7% | 84.5% |
| 4hs5A00 | 3.30.920.10 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY | 0.63 | 47.0 | 3.81e-01 | 88.7% | 41.0% |
| 1npeA00 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.63 | 50.0 | 3.21e-01 | 88.7% | 31.6% |
| 1itvA00 | 2.110.10.10 | Mainly Beta › 4 Propeller › Hemopexin › Hemopexin-like domain | 0.63 | 51.0 | 3.48e-01 | 90.6% | 66.2% |
| 3lv0A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.63 | 46.0 | 3.41e-01 | 79.2% | 96.4% |
| 4chjA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.63 | 50.0 | 3.85e-01 | 88.7% | 83.1% |
| 4cciA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.62 | 45.0 | 2.95e-01 | 79.2% | 83.5% |
| 6v55A02 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.62 | 44.0 | 3.04e-01 | 77.4% | 50.3% |
| 5jozA01 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.61 | 52.0 | 3.27e-01 | 98.1% | 50.8% |
| 1lbvA01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.61 | 44.0 | 3.35e-01 | 79.2% | 52.2% |
| 4j4hA01 | 3.40.50.12150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.61 | 44.0 | 3.29e-01 | 77.4% | 65.9% |
| 2f9zC00 | 3.30.1330.200 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › | 0.61 | 43.0 | 3.17e-01 | 77.4% | 98.1% |
| 1zq7A01 | 3.30.700.20 | Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Hypothetical protein ph0010; domain 1 | 0.60 | 50.0 | 3.82e-01 | 94.3% | 91.3% |
| 4whiA00 | 2.40.128.600 | Mainly Beta › Beta Barrel › Lipocalin › | 0.60 | 43.0 | 3.55e-01 | 79.2% | 58.8% |
| 4r3dA03 | 2.60.120.1680 | Mainly Beta › Sandwich › Jelly Rolls › | 0.58 | 44.0 | 3.33e-01 | 84.9% | 65.7% |
| 4csdB00 | 2.120.10.70 | Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin | 0.58 | 44.0 | 2.95e-01 | 92.5% | 62.9% |
| 3i7dA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.57 | 39.0 | 2.91e-01 | 73.6% | 58.6% |
| 3l2hA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.57 | 42.0 | 3.10e-01 | 81.1% | 68.7% |
| 4m00A01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.57 | 42.0 | 2.81e-01 | 83.0% | 86.6% |
| 2xi9B01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 41.0 | 3.44e-01 | 83.0% | 62.6% |
| 5mu3B00 | 3.40.50.12050 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 42.0 | 3.07e-01 | 88.7% | 66.9% |
| 3q7yA00 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.54 | 37.0 | 2.87e-01 | 71.7% | 77.4% |
| 4a0tA01 | 6.20.80.10 | Special › Other non-globular › Glycosyl hydrolase fold › | 0.54 | 37.0 | 3.63e-01 | 75.5% | 73.8% |
| 2q5iA03 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.53 | 38.0 | 3.17e-01 | 86.8% | 90.9% |
| 5g56A03 | 2.80.10.50 | Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › | 0.51 | 35.0 | 2.85e-01 | 75.5% | 90.3% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5004274 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.79 | 63.0 | 5.51e-01 | 84.9% | 72.0% |
| 3914736 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.74 | 52.0 | 4.90e-01 | 79.2% | 60.0% |
| 3911194 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.74 | 53.0 | 4.63e-01 | 79.2% | 50.0% |
| 4954562 | 10.29.1.0 ↗ | beta sandwiches › jelly-roll › Jelly-roll domain in distal tail protein (Dit)-like proteins › Jelly-roll domain in distal tail protein (Dit)-like proteins | 0.74 | 59.0 | 4.54e-01 | 88.7% | 71.7% |
| 3617714 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.72 | 51.0 | 4.59e-01 | 79.2% | 53.3% |
| 3921414 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.71 | 51.0 | 4.46e-01 | 79.2% | 50.6% |
| 3996720 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.71 | 52.0 | 4.76e-01 | 79.2% | 58.6% |
| 3457638 | 4357.1.1.6 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE_5 | 0.71 | 53.0 | 4.42e-01 | 79.2% | 47.8% |
| 3808306 | 5.1.4.550 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Kelch_FKB95 | 0.71 | 59.0 | 3.58e-01 | 90.6% | 39.3% |
| 3696318 | 5.1.4.249 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_pof12 | 0.71 | 60.0 | 3.52e-01 | 92.5% | 31.2% |
| 3622446 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.70 | 51.0 | 4.66e-01 | 79.2% | 58.6% |
| 3874262 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.70 | 52.0 | 4.06e-01 | 79.2% | 43.6% |
| 3248668 | 79.1.1.0 ↗ | beta duplicates or obligate multimers › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain › Phage tail fiber protein trimerization domain | 0.69 | 51.0 | 4.46e-01 | 81.1% | 52.5% |
| 3783291 | 5.1.4.19 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Coatomer_WDAD | 0.69 | 55.0 | 3.39e-01 | 86.8% | 36.5% |
| 3645247 | 4357.1.1.6 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE_5 | 0.69 | 48.0 | 4.18e-01 | 79.2% | 47.1% |
| 3543691 | 5.1.3.6 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 | 0.68 | 56.0 | 3.52e-01 | 92.5% | 45.4% |
| 2793306 | 4279.1.1.1 ↗ | a+b three layers › DisA nucleotide-binding domain › DisA nucleotide-binding domain › DisA nucleotide-binding domain › DAC | 0.68 | 49.0 | 3.48e-01 | 75.5% | 74.7% |
| 3938729 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.68 | 53.0 | 3.35e-01 | 86.8% | 30.5% |
| 5003472 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.67 | 51.0 | 3.81e-01 | 83.0% | 84.4% |
| 4986395 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.67 | 51.0 | 3.47e-01 | 83.0% | 58.5% |
| 3827259 | 5.1.4.550 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Kelch_FKB95 | 0.67 | 55.0 | 3.42e-01 | 90.6% | 42.5% |
| 3839277 | 241.16.1.1 ↗ | a+b two layers › Type III secretory system chaperone-like › protein CagD › protein CagD › CagD | 0.66 | 52.0 | 3.87e-01 | 88.7% | 64.8% |
| 4958290 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.66 | 50.0 | 3.13e-01 | 83.0% | 36.2% |
| 3458699 | 376.1.2.2 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_2 | 0.66 | 49.0 | 3.48e-01 | 81.1% | 61.3% |
| 4934604 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.66 | 51.0 | 3.15e-01 | 84.9% | 36.5% |
| 4958164 | 298.1.1.42 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA | 0.65 | 50.0 | 3.10e-01 | 83.0% | 37.4% |
| 5078978 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.65 | 55.0 | 3.49e-01 | 94.3% | 36.2% |
| 5078256 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.65 | 49.0 | 3.37e-01 | 83.0% | 59.0% |
| 3229102 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.65 | 44.0 | 2.85e-01 | 83.0% | 15.2% |
| 4990696 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.65 | 51.0 | 3.17e-01 | 86.8% | 36.2% |
| 3990049 | 298.1.1.0 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.65 | 51.0 | 3.10e-01 | 88.7% | 36.4% |
| 3910321 | 391.1.2.23 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related › VWD | 0.64 | 50.0 | 3.26e-01 | 86.8% | 32.7% |
| 26896 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.64 | 47.0 | 4.11e-01 | 81.1% | 52.3% |
| 3814929 | 5.1.5.86 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Kelch_1 | 0.64 | 53.0 | 3.30e-01 | 92.5% | 43.4% |
| 3771735 | 6129.1.1.1 ↗ | beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD | 0.64 | 50.0 | 3.36e-01 | 86.8% | 39.5% |
| 5000582 | 298.1.1.0 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.64 | 46.0 | 3.63e-01 | 77.4% | 87.8% |
| 4241220 | 5.1.3.48 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Gmad1 | 0.64 | 52.0 | 3.32e-01 | 92.5% | 41.5% |
| 4956654 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.64 | 48.0 | 3.32e-01 | 83.0% | 60.5% |
| 3283531 | 5.1.3.23 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › SGL | 0.64 | 55.0 | 3.46e-01 | 94.3% | 29.8% |
| 3475247 | 4184.1.1.1 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › DM9 | 0.64 | 47.0 | 4.32e-01 | 79.2% | 61.4% |
| 3247178 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.64 | 47.0 | 4.17e-01 | 81.1% | 55.0% |
| 5037561 | 298.1.1.0 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0.63 | 47.0 | 3.73e-01 | 83.0% | 91.7% |
| 3925881 | 5.1.4.407 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RCC1, RCC1_2, Alsin_RLD | 0.63 | 53.0 | 3.25e-01 | 100.0% | 58.5% |
| 3176855 | 5.1.4.258 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RCC1, RCC1_2 | 0.63 | 50.0 | 2.96e-01 | 90.6% | 24.9% |
| 3272453 | 6.1.1.7 ↗ | beta duplicates or obligate multimers › beta-Trefoil › beta-Trefoil › beta-Trefoil › CDtoxinA | 0.63 | 49.0 | 3.67e-01 | 86.8% | 38.5% |
| 3556708 | 247.1.1.38 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C | 0.62 | 48.0 | 4.31e-01 | 84.9% | 62.7% |
| 4045923 | 4184.1.1.0 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat | 0.62 | 44.0 | 4.18e-01 | 79.2% | 63.1% |
| 4142302 | 5.1.4.16 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A | 0.62 | 51.0 | 3.14e-01 | 94.3% | 40.9% |
| 4927792 | 2003.1.1.22 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GFO_IDH_MocA | 0.62 | 47.0 | 2.90e-01 | 83.0% | 34.8% |
| 3214587 | 4357.1.1.1 ↗ | beta barrels › WWE domain › WWE domain › WWE domain › WWE | 0.61 | 48.0 | 4.22e-01 | 86.8% | 61.3% |
| 3483268 | 4184.1.1.0 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat | 0.61 | 45.0 | 4.05e-01 | 79.2% | 57.3% |
| 3263503 | 331.4.1.9 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › CPSF73-100_C | 0.61 | 48.0 | 4.36e-01 | 88.7% | 62.7% |
| 3826594 | 5.1.3.65 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF295 | 0.61 | 50.0 | 3.18e-01 | 94.3% | 42.8% |
| 3496211 | 4184.1.1.0 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat | 0.60 | 44.0 | 4.08e-01 | 79.2% | 61.4% |
| 3627280 | 331.23.1.0 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain | 0.60 | 46.0 | 4.10e-01 | 83.0% | 60.0% |
| 3619889 | 331.23.1.7 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › CPSF73-100_C | 0.60 | 46.0 | 4.25e-01 | 88.7% | 64.3% |
| 3516397 | 6129.1.1.1 ↗ | beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD | 0.60 | 45.0 | 3.16e-01 | 83.0% | 26.5% |
| 4977715 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.60 | 44.0 | 3.47e-01 | 81.1% | 76.5% |
| 3409029 | 331.23.1.2 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › IntS9_C | 0.60 | 46.0 | 4.12e-01 | 83.0% | 63.5% |
| 3386489 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.59 | 41.0 | 2.95e-01 | 71.7% | 22.4% |
| 4997629 | 298.1.1.24 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › GFO_IDH_MocA_C3 | 0.59 | 46.0 | 3.25e-01 | 88.7% | 71.4% |
| 3550365 | 331.23.1.2 ↗ | a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › IntS9_C | 0.58 | 44.0 | 3.89e-01 | 81.1% | 59.0% |
| 4115428 | 71.1.1.2 ↗ | beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA | 0.58 | 45.0 | 3.16e-01 | 86.8% | 83.3% |
| 3389451 | 4184.1.1.1 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › DM9 | 0.57 | 43.0 | 3.88e-01 | 83.0% | 64.0% |
| 3595832 | 375.8.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Zinc-binding domain of translation initiation factor 2 beta › Zinc-binding domain of translation initiation factor 2 beta | 0.57 | 39.0 | 3.87e-01 | 71.7% | 78.2% |
| 3823449 | 219.1.1.3 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH | 0.57 | 43.0 | 2.83e-01 | 90.6% | 82.8% |
| 3799652 | 4184.1.1.2 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat › MFP2b | 0.57 | 40.0 | 3.46e-01 | 79.2% | 65.3% |
| 4990232 | 247.1.1.0 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase | 0.55 | 44.0 | 3.08e-01 | 90.6% | 55.8% |
| 3493489 | 64.1.1.0 ↗ | beta meanders › WW domain-like › WW domain › WW domain | 0.55 | 37.0 | 3.83e-01 | 71.7% | 92.0% |
| 3916099 | 6129.1.1.1 ↗ | beta barrels › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › Repulsive guidance molecule (RGM) family › VWD | 0.55 | 43.0 | 3.04e-01 | 88.7% | 28.3% |
| 3247669 | 207.1.1.81 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH | 0.55 | 37.0 | 2.47e-01 | 79.2% | 15.1% |
| 5078886 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.54 | 41.0 | 3.46e-01 | 92.5% | 73.6% |
| 3786814 | 5.1.2.20 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › BMT | 0.53 | 43.0 | 2.61e-01 | 100.0% | 24.3% |
| 3743110 | 220.1.1.19 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › Rttp106-like_middle | 0.50 | 38.0 | 3.24e-01 | 90.6% | 47.6% |
| 4544724 | 243.6.1.9 ↗ | a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › TGT_C2 | 0.50 | 40.0 | 3.60e-01 | 88.7% | 88.0% |
D3
medium
residues 90-142
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6t4hA03 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.76 | 66.0 | 4.65e-01 | 100.0% | 49.4% |
| 7craA02 | 1.20.58.1480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 58.0 | 4.89e-01 | 92.5% | 90.2% |
| 2el7A02 | 1.10.240.10 | Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase | 0.70 | 59.0 | 4.98e-01 | 98.1% | 71.3% |
| 2a73B01 | 1.20.91.20 | Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Anaphylotoxins (complement system) | 0.70 | 45.0 | 4.15e-01 | 86.8% | 51.4% |
| 4ci1B03 | 1.20.58.1480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 47.0 | 4.37e-01 | 81.1% | 92.8% |
| 1s4eG02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.61 | 45.0 | 3.24e-01 | 79.2% | 60.1% |
| 2cgqA00 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.61 | 43.0 | 4.00e-01 | 79.2% | 100.0% |
| 4ikmA02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.61 | 48.0 | 4.13e-01 | 94.3% | 66.7% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.60 | 46.0 | 4.01e-01 | 83.0% | 63.0% |
| 2kqzA01 | 1.10.2020.20 | Mainly Alpha › Orthogonal Bundle › uronate isomerase, domain 2, chain A › | 0.60 | 51.0 | 3.96e-01 | 100.0% | 75.4% |
| 4c0nA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.59 | 51.0 | 3.68e-01 | 96.2% | 97.3% |
| 6ncvA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.58 | 44.0 | 3.86e-01 | 88.7% | 69.2% |
| 1ypwA06 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 42.0 | 3.94e-01 | 83.0% | 63.1% |
| 1w2lA00 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.56 | 38.0 | 3.13e-01 | 71.7% | 47.4% |
| 4cfsA02 | 1.10.210.20 | Mainly Alpha › Orthogonal Bundle › Uteroglobin › | 0.55 | 47.0 | 4.29e-01 | 96.2% | 82.9% |
| 2dbhA01 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.55 | 44.0 | 3.96e-01 | 94.3% | 73.4% |
| 4pxhB00 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.53 | 36.0 | 3.38e-01 | 75.5% | 94.7% |
| 1mkmB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 37.0 | 3.26e-01 | 75.5% | 59.2% |
| 3u4qA02 | 1.10.274.50 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.50 | 41.0 | 3.10e-01 | 100.0% | 87.3% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3873540 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.75 | 53.0 | 3.65e-01 | 73.6% | 48.8% |
| 3255531 | 632.7.1.25 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › PF27508 | 0.70 | 51.0 | 4.35e-01 | 77.4% | 95.3% |
| 3480389 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.70 | 48.0 | 4.11e-01 | 71.7% | 63.7% |
| 3735664 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.70 | 60.0 | 3.61e-01 | 98.1% | 16.1% |
| 3175305 | 101.1.2.167 ↗ | alpha arrays › HTH › HTH › winged helix domain › XRN1_D2_D3 | 0.68 | 52.0 | 3.84e-01 | 81.1% | 74.6% |
| 3430906 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.68 | 59.0 | 4.94e-01 | 96.2% | 81.1% |
| 4957054 | 101.1.2.743 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF28795 | 0.67 | 38.0 | 3.67e-01 | 71.7% | 49.2% |
| 3269634 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.67 | 54.0 | 5.26e-01 | 90.6% | 88.3% |
| 3930908 | 105.1.1.0 ↗ | alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain | 0.64 | 46.0 | 4.62e-01 | 77.4% | 96.4% |
| 3423523 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.64 | 53.0 | 4.36e-01 | 88.7% | 81.1% |
| 3959794 | 132.1.1.0 ↗ | alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) | 0.62 | 47.0 | 4.01e-01 | 90.6% | 88.0% |
| 2103762 | 148.1.3.19 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 | 0.62 | 43.0 | 4.14e-01 | 73.6% | 83.3% |
| 3729903 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.55 | 35.0 | 3.30e-01 | 98.1% | 48.6% |
| 3286630 | 213.1.1.1 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 | 0.50 | 41.0 | 2.98e-01 | 98.1% | 31.8% |
| 3797643 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.50 | 42.0 | 3.11e-01 | 90.6% | 86.9% |