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5H_04062016_scaffold_1_prodigal-single.1__X__X__00421

Bact-Vir

5H_04062016_scaffold_1_prodigal-single.1__X__X__00421

Identity

Kingdom:
phage

Quality

92.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-57
PDB
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2in5A00 2.40.360.10 Mainly Beta › Beta Barrel › YmcC-like fold › YmcC-like 0.79 70.0 4.76e-01 98.2% 35.4%
4ge6A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.77 58.0 3.62e-01 94.7% 15.2%
2i1yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.72 55.0 3.52e-01 94.7% 16.7%
4jocA00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.72 55.0 3.37e-01 84.2% 89.0%
2bzlA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.71 56.0 3.55e-01 94.7% 17.6%
5hdwA00 2.60.40.1470 Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain 0.71 63.0 4.80e-01 100.0% 95.4%
3hn3A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.69 55.0 4.50e-01 86.0% 77.9%
2qkdA01 2.20.25.420 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain 0.68 53.0 5.64e-01 89.5% 100.0%
1a5yA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.68 57.0 3.59e-01 94.7% 18.7%
1ni9A01 3.30.540.10 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 0.68 58.0 4.24e-01 94.7% 37.7%
4dy0B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.68 45.0 3.37e-01 77.2% 30.5%
2ia7A00 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.67 54.0 4.43e-01 94.7% 46.8%
3khpD01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.67 56.0 4.25e-01 93.0% 89.7%
1gofA02 2.130.10.80 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Galactose oxidase/kelch, beta-propeller 0.66 59.0 3.54e-01 100.0% 25.5%
5xd7A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.66 53.0 4.11e-01 89.5% 40.2%
1ygaA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.65 54.0 3.36e-01 93.0% 17.0%
2krtA01 3.10.450.270 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 55.0 4.55e-01 94.7% 56.3%
4nehA04 2.60.40.1510 Mainly Beta › Sandwich › Immunoglobulin-like › ntegrin, alpha v. Chain A, domain 3 0.65 55.0 3.94e-01 91.2% 76.6%
3ijlA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.65 51.0 4.16e-01 86.0% 49.1%
2gjvA00 3.30.2000.10 Alpha Beta › 2-Layer Sandwich › STM4215-like › Phage tail protein-like 0.65 55.0 4.18e-01 94.7% 94.1%
4dduA07 2.60.510.20 Mainly Beta › Sandwich › EV matrix protein fold › 0.65 54.0 4.43e-01 93.0% 72.0%
3lidA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.65 51.0 3.98e-01 89.5% 97.8%
2r39A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.65 52.0 4.29e-01 91.2% 96.3%
2chrA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.65 53.0 4.12e-01 91.2% 47.2%
4apxB01 2.60.40.3430 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 53.0 4.12e-01 89.5% 61.7%
1cb8A03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.63 56.0 4.46e-01 96.5% 61.8%
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.63 49.0 4.84e-01 91.2% 79.4%
4b60A02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 55.0 4.04e-01 100.0% 96.2%
8fkmA01 3.30.1460.50 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.62 51.0 3.83e-01 98.2% 43.3%
3cyjA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.62 51.0 3.99e-01 91.2% 97.5%
5oyjC01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 50.0 4.13e-01 86.0% 66.3%
3mcrA00 3.30.460.80 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › NADH:ubiquinone oxidoreductase Nqo5 subunit 0.61 50.0 3.78e-01 96.5% 53.9%
3kojB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 49.0 4.29e-01 93.0% 56.7%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.61 48.0 4.60e-01 91.2% 73.9%
4jhcB00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.61 52.0 3.72e-01 98.2% 87.4%
2pn5A03 2.60.40.1940 Mainly Beta › Sandwich › Immunoglobulin-like › 0.61 53.0 4.30e-01 96.5% 79.0%
6s8zA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.60 46.0 4.59e-01 91.2% 80.6%
4jdzA02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 51.0 3.76e-01 100.0% 97.0%
1vp2A00 3.90.950.10 Alpha Beta › Alpha-Beta Complex › Maf protein › 0.60 52.0 3.65e-01 98.2% 89.9%
1pbyB00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.60 52.0 3.24e-01 100.0% 16.9%
3wa2X01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 48.0 4.29e-01 93.0% 71.3%
4gn2A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.60 48.0 3.36e-01 100.0% 60.0%
1fx3B00 3.10.420.10 Alpha Beta › Roll › Bacterial Protein-export protein SecB › SecB-like 0.60 49.0 3.66e-01 91.2% 65.8%
1n7vA02 2.60.330.10 Mainly Beta › Sandwich › receptor-binding protein prd1-p2, domain 2 › receptor-binding protein prd1-p2, domain 2 0.60 52.0 4.05e-01 98.2% 67.5%
3gwrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 50.0 3.94e-01 96.5% 81.1%
4b63A00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.59 51.0 3.03e-01 100.0% 35.0%
3a5zB01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.59 45.0 4.47e-01 91.2% 79.4%
5df7A02 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.59 49.0 3.11e-01 100.0% 18.4%
2b39A03 2.60.40.1940 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 50.0 3.91e-01 96.5% 77.6%
3c7fA02 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.59 49.0 3.08e-01 100.0% 27.5%
1l3aA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.59 49.0 3.58e-01 96.5% 36.1%
8ouzD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 52.0 3.37e-01 96.5% 89.1%
4j8tA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.58 49.0 3.82e-01 96.5% 75.0%
4q9cA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 46.0 3.84e-01 91.2% 81.0%
3oyyA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.57 44.0 4.27e-01 91.2% 77.3%
4i4kA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 49.0 3.77e-01 100.0% 77.5%
6kghA02 3.30.450.330 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.57 47.0 3.59e-01 100.0% 44.8%
4mbrA02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 3.48e-01 100.0% 89.2%
2vzsA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 46.0 3.65e-01 93.0% 69.1%
2be3B01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.56 45.0 3.50e-01 94.7% 38.5%
2rfrA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 46.0 3.52e-01 100.0% 70.8%
1ss4A00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.56 45.0 3.47e-01 96.5% 39.6%
4i0kA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 44.0 3.66e-01 84.2% 71.6%
1gesA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.55 41.0 3.38e-01 82.5% 45.1%
3qf7A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 45.0 2.94e-01 96.5% 34.4%
4q0yA00 2.60.40.4400 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 43.0 3.38e-01 91.2% 95.4%
2wjsA02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.52 44.0 3.15e-01 98.2% 51.9%
2xglA00 3.10.450.300 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › YebF/Colicin-M immunity protein 0.52 42.0 3.77e-01 98.2% 79.1%
4blqA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 43.0 2.82e-01 98.2% 64.0%
5eqxA04 2.60.40.60 Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins 0.51 38.0 3.29e-01 87.7% 79.8%
2g2sA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.51 36.0 3.52e-01 84.2% 67.2%
6gp1A00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.50 35.0 3.36e-01 80.7% 63.1%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3266842 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.75 61.0 4.66e-01 87.7% 67.2%
3811861 5.1.3.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.74 67.0 4.06e-01 100.0% 17.1%
3625916 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.73 65.0 3.93e-01 100.0% 16.1%
3957639 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.72 65.0 4.11e-01 100.0% 23.4%
3962355 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.72 65.0 4.41e-01 100.0% 34.0%
3959921 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.72 63.0 5.67e-01 96.5% 72.2%
None 0.72 65.0 3.97e-01 100.0% 20.3%
3962256 295.1.1.32 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › DDE_Tnp_1 0.72 65.0 4.87e-01 100.0% 50.4%
3958189 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.72 65.0 4.97e-01 100.0% 54.4%
3961876 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 64.0 3.91e-01 100.0% 19.4%
3855429 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 58.0 3.30e-01 100.0% 9.0%
3565146 109.4.1.816 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RALGAPB_N 0.69 58.0 3.16e-01 100.0% 5.3%
3797649 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.69 53.0 4.24e-01 82.5% 50.9%
3622698 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.69 62.0 3.77e-01 100.0% 16.8%
3628265 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.68 59.0 3.55e-01 100.0% 14.1%
3824181 375.1.1.21 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 0.68 56.0 5.59e-01 93.0% 93.3%
4029311 5.1.4.73 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RAB3GAP2_N 0.68 58.0 3.52e-01 94.7% 87.7%
167858 218.1.1.1 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.68 51.0 3.94e-01 80.7% 38.4%
3696153 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.68 56.0 3.53e-01 94.7% 83.2%
3623547 295.1.1.4 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.68 55.0 5.21e-01 93.0% 81.4%
4990492 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.67 52.0 5.46e-01 84.2% 94.0%
3969465 6043.1.1.0 a+b two layers › yfeY-like › yfeY-like › yfeY-like 0.67 53.0 4.72e-01 86.0% 63.7%
4416182 241.15.1.3 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › SPC25 0.67 60.0 4.82e-01 98.2% 61.9%
3591236 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.67 54.0 3.05e-01 91.2% 7.9%
3586270 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.66 57.0 3.44e-01 100.0% 14.0%
3221229 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.66 48.0 5.08e-01 91.2% 100.0%
5018715 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.66 54.0 5.35e-01 91.2% 95.0%
5036880 330.1.1.35 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › LeuA_dimer 0.66 52.0 4.92e-01 93.0% 71.4%
5023738 11.1.1.1443 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29994 0.65 57.0 4.53e-01 94.7% 56.4%
3277040 12.1.1.0 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.65 53.0 4.22e-01 89.5% 99.1%
4957500 283.2.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like 0.65 55.0 4.64e-01 93.0% 62.1%
3184113 318.1.1.0 a+b two layers › Ribosomal protein L6 › Ribosomal protein L6 › Ribosomal protein L6 0.65 53.0 4.42e-01 91.2% 63.0%
3476117 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.65 55.0 4.30e-01 91.2% 47.0%
5030911 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.65 54.0 4.77e-01 93.0% 83.1%
3717505 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 55.0 4.79e-01 94.7% 92.9%
3602244 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.64 54.0 4.02e-01 94.7% 37.5%
4004011 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.64 53.0 4.30e-01 93.0% 55.5%
4986251 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.64 50.0 4.26e-01 87.7% 53.3%
5017212 11.1.1.1443 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF29994 0.63 55.0 4.35e-01 96.5% 57.4%
4311607 4272.1.1.1 a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.63 52.0 3.99e-01 96.5% 63.6%
4221476 2003.1.2.28 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Lys_Orn_oxgnase 0.63 50.0 3.45e-01 89.5% 91.9%
3715739 5.1.3.28 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 0.63 54.0 3.21e-01 98.2% 20.5%
4514345 274.1.1.50 a+b two layers › Pili subunits › Pili subunits › Pili subunits › Spore_YunB 0.62 49.0 3.74e-01 89.5% 73.1%
4842604 4272.1.1.1 a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.62 51.0 4.41e-01 96.5% 86.5%
3285008 5.1.4.15 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › RPE65 0.62 56.0 3.30e-01 98.2% 19.6%
3736443 2003.1.2.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like 0.62 54.0 3.36e-01 98.2% 55.9%
3934566 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 52.0 3.88e-01 96.5% 73.3%
2546240 5.1.3.35 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Neuraminidase 0.62 52.0 3.63e-01 100.0% 37.3%
3999173 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.62 46.0 3.82e-01 82.5% 47.4%
3458732 243.3.1.19 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 0.61 52.0 5.15e-01 93.0% 93.3%
3712703 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.61 53.0 3.38e-01 100.0% 38.7%
3562153 5.1.3.147 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Beta-prop_ATRN-LZTR1 0.61 56.0 3.43e-01 100.0% 27.3%
3608162 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.61 49.0 3.58e-01 91.2% 34.5%
4289288 330.6.1.1 a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › LeuA_dimer 0.61 52.0 4.12e-01 100.0% 46.1%
3632708 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.61 51.0 3.05e-01 94.7% 23.6%
3477257 5.1.4.148 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WDR93 0.61 52.0 3.08e-01 100.0% 12.0%
3744143 220.1.1.32 beta barrels › PH domain-like › PH domain-like › PH domain-like › Sec3-PIP2_bind 0.60 50.0 3.83e-01 100.0% 47.3%
3618875 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.60 49.0 3.75e-01 93.0% 38.5%
3492069 4292.2.1.2 a+b two layers › FlaG-like › MAGUK binding stalk (MBS) domain › MAGUK binding stalk (MBS) domain › KIF1B 0.60 49.0 4.13e-01 96.5% 57.1%
3268888 2.1.1.44 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Dna2 0.60 45.0 4.02e-01 91.2% 55.6%
3282536 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.59 49.0 4.51e-01 100.0% 77.5%
3675847 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.59 50.0 3.17e-01 96.5% 31.2%
3472659 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.59 50.0 3.77e-01 93.0% 38.6%
3701124 4252.1.1.1 beta barrels › AttH-like › AttH-like › AttH-like › CrtC 0.59 50.0 3.57e-01 100.0% 45.8%
3972242 7503.1.1.0 a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain 0.59 51.0 3.74e-01 100.0% 81.2%
3990824 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 47.0 4.06e-01 87.7% 58.9%
4297163 218.1.1.1 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.59 48.0 3.96e-01 91.2% 51.4%
4926981 9.13.1.0 beta barrels › Lipocalins/Streptavidin › AOC barrel-like › AOC barrel-like 0.58 50.0 3.99e-01 100.0% 81.6%
3348586 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 47.0 3.37e-01 89.5% 57.7%
4314504 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.58 51.0 3.88e-01 98.2% 95.6%
None 0.58 50.0 3.04e-01 100.0% 14.4%
3930653 243.3.1.1 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Cystatin 0.58 48.0 4.16e-01 93.0% 58.9%
4131098 218.1.1.0 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like 0.58 46.0 3.92e-01 91.2% 55.0%
3581448 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.58 52.0 4.08e-01 100.0% 61.7%
3392249 223.2.1.36 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_3 0.58 41.0 3.06e-01 77.2% 31.0%
3273166 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 51.0 3.14e-01 100.0% 30.7%
3962610 223.3.1.3 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.57 48.0 3.57e-01 98.2% 52.3%
5044388 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.57 45.0 4.72e-01 89.5% 100.0%
3417120 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.56 47.0 3.84e-01 100.0% 70.0%
4873579 4019.1.1.3 alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.55 43.0 3.99e-01 94.7% 66.7%
3576019 246.3.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.55 43.0 2.68e-01 91.2% 17.5%
4973410 881.1.1.0 a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.55 43.0 3.37e-01 100.0% 38.7%
3702616 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.54 45.0 3.62e-01 100.0% 68.8%
4021308 2485.2.1.0 a+b three layers › Thioredoxin-like › RNA 3'-terminal phosphate cyclase, RPTC, insert domain › RNA 3'-terminal phosphate cyclase, RPTC, insert domain 0.53 42.0 3.38e-01 87.7% 81.7%
4888978 2485.2.1.1 a+b three layers › Thioredoxin-like › RNA 3'-terminal phosphate cyclase, RPTC, insert domain › RNA 3'-terminal phosphate cyclase, RPTC, insert domain › RTC_insert 0.53 43.0 3.55e-01 91.2% 81.1%
4965032 375.1.1.343 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DUF7835 0.53 40.0 4.06e-01 87.7% 100.0%
5052424 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.52 40.0 3.20e-01 91.2% 37.9%
3640328 4.1.1.411 beta barrels › SH3 › SH3 › SH3 › Pkinase_fungal 0.52 41.0 3.92e-01 91.2% 87.1%
3509244 11.1.1.41 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_C 0.51 43.0 3.21e-01 100.0% 83.6%
4771028 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.51 36.0 3.56e-01 84.2% 68.3%
2490256 271.1.1.1 beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.50 35.0 3.35e-01 80.7% 62.1%
D2 medium residues 58-134
PDB
Domain cluster: representative
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.78 42.0 3.68e-01 98.7% 37.0%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 41.0 4.41e-01 98.7% 63.1%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 53.0 4.60e-01 89.6% 95.8%
3tacB01 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.62 44.0 3.81e-01 75.3% 70.9%
6zhiB02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 43.0 4.21e-01 74.0% 67.5%
2yn7A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.60 43.0 3.13e-01 75.3% 37.9%
4u1cA01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.58 38.0 4.39e-01 77.9% 98.1%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.58 38.0 3.76e-01 72.7% 61.9%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.58 42.0 4.04e-01 77.9% 86.8%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 41.0 4.07e-01 75.3% 75.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 41.0 3.77e-01 74.0% 74.5%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 37.0 3.18e-01 74.0% 40.2%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 47.0 4.15e-01 90.9% 63.7%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.57 45.0 3.78e-01 85.7% 72.2%
1m4rB00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 42.0 3.54e-01 90.9% 44.0%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 45.0 3.93e-01 87.0% 59.3%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.56 37.0 3.46e-01 72.7% 53.6%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 46.0 3.99e-01 89.6% 61.5%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.56 42.0 4.40e-01 92.2% 92.9%
1lujB01 1.10.10.490 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Beta-catenin-interacting ICAT 0.56 34.0 3.89e-01 75.3% 88.7%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.55 38.0 3.67e-01 71.4% 62.8%
2vf8B02 1.20.1580.10 Mainly Alpha › Up-down Bundle › ABC transporter ATPase like fold › ABC transporter ATPase like domain 0.55 45.0 3.57e-01 89.6% 61.0%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 42.0 3.24e-01 80.5% 40.1%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 42.0 3.81e-01 80.5% 73.5%
7vwtA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 42.0 2.80e-01 81.8% 46.7%
4mc3A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.55 41.0 2.85e-01 81.8% 35.2%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 43.0 4.47e-01 98.7% 89.0%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 41.0 3.53e-01 80.5% 69.1%
1ux8A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 38.0 3.31e-01 75.3% 50.8%
2qsaA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.53 37.0 3.40e-01 72.7% 71.3%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.53 43.0 3.71e-01 92.2% 66.1%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.52 43.0 3.84e-01 97.4% 86.3%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 37.0 3.56e-01 77.9% 80.9%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.51 41.0 3.50e-01 94.8% 67.8%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.51 43.0 4.35e-01 100.0% 93.3%
3q9oA02 3.90.1350.10 Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain 0.50 42.0 3.43e-01 100.0% 89.8%
1x9fD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 36.0 3.03e-01 83.1% 40.0%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4051951 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.70 45.0 4.31e-01 98.7% 56.7%
4934784 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.67 38.0 3.75e-01 98.7% 51.8%
4885878 601.1.1.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CHASE3 0.65 44.0 3.51e-01 98.7% 36.7%
4023387 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.60 42.0 3.92e-01 74.0% 60.0%
3612380 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 53.0 5.04e-01 98.7% 84.4%
5038395 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 51.0 4.14e-01 98.7% 81.3%
4947713 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.58 46.0 4.09e-01 84.4% 91.8%
4237962 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.58 44.0 2.80e-01 97.4% 14.4%
3326073 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.57 41.0 3.70e-01 76.6% 61.8%
3713780 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.57 42.0 3.61e-01 77.9% 60.0%
3318544 150.1.1.78 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rx_N 0.57 37.0 3.71e-01 72.7% 63.7%
4891169 109.4.1.259 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tra1_ring 0.57 42.0 2.77e-01 79.2% 31.4%
3583102 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 40.0 3.99e-01 75.3% 77.5%
3714029 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 42.0 3.21e-01 81.8% 38.9%
56761 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.55 41.0 3.51e-01 90.9% 46.0%
3760483 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.55 44.0 3.25e-01 98.7% 34.7%
3289263 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.55 43.0 4.57e-01 98.7% 92.9%
4022148 2492.1.1.32 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › OTT_1508_deam 0.55 45.0 3.12e-01 92.2% 76.1%
4929471 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.55 48.0 3.66e-01 100.0% 52.1%
5006528 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.54 38.0 3.88e-01 72.7% 78.7%
3944950 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.54 37.0 4.04e-01 72.7% 84.6%
3870489 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.54 47.0 3.95e-01 98.7% 97.8%
4083384 3054.1.1.0 alpha arrays › Insert all-alpha domain in prim-pol › Insert all-alpha domain in prim-pol › Insert all-alpha domain in prim-pol 0.54 44.0 4.05e-01 90.9% 91.4%
3976077 5059.1.1.20 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › DUF1422 0.54 45.0 4.04e-01 96.1% 100.0%
5052279 632.1.1.2 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › BE_C 0.53 40.0 3.51e-01 81.8% 66.7%
3952558 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.53 42.0 3.71e-01 100.0% 57.4%
4675002 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.53 43.0 3.68e-01 92.2% 55.4%
56928 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.52 43.0 3.87e-01 96.1% 73.0%
3963380 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.52 40.0 3.21e-01 84.4% 89.1%
3680918 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.52 38.0 4.07e-01 98.7% 92.3%
4982912 7014.1.1.0 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain 0.52 36.0 3.46e-01 72.7% 73.3%
4016436 3324.1.1.1 extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › MTR4_beta-barrel 0.52 44.0 3.91e-01 94.8% 76.4%
3573621 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.51 42.0 3.39e-01 92.2% 80.6%
3714267 1075.4.1.2 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 0.50 42.0 2.75e-01 93.5% 94.4%