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AF335538.1__AAK28906.1__X__00058
Bact-VirAF335538.1__AAK28906.1__X__00058
Identity
- Accession:
- AF335538 ↗
- Kingdom:
- phage
Quality
86.2
mean pLDDT
Taxonomy
TaxID: 155148
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 94-207
Domain cluster:
representative
CATH (40)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4d49A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.70 | 47.0 | 3.66e-01 | 91.2% | 32.8% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 53.0 | 5.21e-01 | 80.7% | 82.4% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 48.0 | 5.22e-01 | 78.9% | 90.4% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 51.0 | 5.36e-01 | 81.6% | 91.2% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 51.0 | 5.03e-01 | 82.5% | 91.7% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 56.0 | 4.49e-01 | 93.9% | 89.2% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 44.0 | 3.93e-01 | 91.2% | 50.6% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 50.0 | 4.22e-01 | 84.2% | 67.7% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.64 | 48.0 | 4.83e-01 | 79.8% | 85.3% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 46.0 | 4.84e-01 | 76.3% | 99.0% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 51.0 | 5.12e-01 | 92.1% | 86.3% |
| 4j5tA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.61 | 52.0 | 3.39e-01 | 91.2% | 51.5% |
| 4u2xF00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 48.0 | 4.13e-01 | 93.9% | 53.7% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 32.0 | 3.77e-01 | 80.7% | 72.2% |
| 2qsbA00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.60 | 33.0 | 3.76e-01 | 74.6% | 70.6% |
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 45.0 | 3.88e-01 | 80.7% | 52.7% |
| 3vhlA02 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.59 | 49.0 | 4.88e-01 | 91.2% | 100.0% |
| 4ffbC00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.58 | 53.0 | 4.16e-01 | 98.2% | 56.3% |
| 4kf9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 48.0 | 4.56e-01 | 90.4% | 98.5% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.57 | 52.0 | 3.88e-01 | 100.0% | 99.3% |
| 2xsbA02 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.57 | 44.0 | 4.10e-01 | 83.3% | 69.8% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 41.0 | 4.05e-01 | 79.8% | 70.0% |
| 5dqqA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 36.0 | 3.50e-01 | 86.0% | 56.1% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 42.0 | 4.23e-01 | 93.9% | 79.6% |
| 3qxlA00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.54 | 46.0 | 3.73e-01 | 98.2% | 47.8% |
| 4ldsA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 47.0 | 3.25e-01 | 98.2% | 99.3% |
| 6hj2A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.54 | 46.0 | 3.45e-01 | 92.1% | 72.6% |
| 2vvwA00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.53 | 37.0 | 3.41e-01 | 88.6% | 54.0% |
| 2ijeS00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.53 | 45.0 | 3.68e-01 | 97.4% | 48.5% |
| 7dvqK01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.53 | 48.0 | 4.14e-01 | 98.2% | 67.1% |
| 3g5uA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 47.0 | 2.92e-01 | 100.0% | 67.1% |
| 4hteA03 | 1.10.167.30 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › | 0.53 | 36.0 | 4.13e-01 | 75.4% | 98.8% |
| 7qocA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.52 | 46.0 | 3.95e-01 | 97.4% | 88.2% |
| 3ecsC01 | 1.20.120.1070 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain | 0.52 | 36.0 | 3.78e-01 | 91.2% | 80.0% |
| 1bk6A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 47.0 | 3.16e-01 | 99.1% | 30.6% |
| 2vkjA00 | 1.20.58.2030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 37.0 | 3.82e-01 | 93.9% | 80.2% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 35.0 | 3.30e-01 | 86.0% | 57.0% |
| 3au4A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.51 | 44.0 | 3.69e-01 | 94.7% | 63.8% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 38.0 | 3.58e-01 | 78.1% | 78.4% |
| 1wu3I00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 37.0 | 3.33e-01 | 76.3% | 77.0% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3393204 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 49.0 | 4.28e-01 | 93.9% | 46.1% |
| 3788450 | 109.4.1.293 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPP2R1A-like_HEAT | 0.74 | 54.0 | 4.45e-01 | 97.4% | 44.1% |
| 3692194 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.72 | 44.0 | 5.23e-01 | 75.4% | 87.5% |
| 3966991 | 7011.1.1.0 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain | 0.70 | 64.0 | 4.28e-01 | 99.1% | 28.1% |
| 3718498 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.70 | 49.0 | 5.46e-01 | 81.6% | 91.1% |
| 4947640 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.69 | 54.0 | 4.08e-01 | 81.6% | 67.1% |
| 3504307 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 54.0 | 5.06e-01 | 81.6% | 70.4% |
| 3690382 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 53.0 | 4.84e-01 | 81.6% | 82.1% |
| 4607338 | 603.1.1.108 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27599 | 0.67 | 61.0 | 4.84e-01 | 98.2% | 73.7% |
| 3218650 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 51.0 | 5.31e-01 | 78.9% | 88.6% |
| 3612348 | 109.4.1.161 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › mTOR_dom | 0.67 | 53.0 | 3.14e-01 | 95.6% | 12.0% |
| 3738934 | 109.4.1.15 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VHS | 0.67 | 48.0 | 4.47e-01 | 93.9% | 59.3% |
| 3689020 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.66 | 51.0 | 3.77e-01 | 81.6% | 64.1% |
| 3715315 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.66 | 51.0 | 3.90e-01 | 81.6% | 66.9% |
| 3647808 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 49.0 | 4.98e-01 | 97.4% | 79.1% |
| 3545235 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.65 | 50.0 | 5.08e-01 | 79.8% | 89.1% |
| None | — | 0.64 | 55.0 | 4.24e-01 | 93.0% | 85.1% | |
| 3462100 | 604.1.1.102 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF8324 | 0.64 | 50.0 | 4.96e-01 | 81.6% | 85.8% |
| 3831934 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 60.0 | 4.24e-01 | 100.0% | 63.7% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.64 | 50.0 | 4.34e-01 | 82.5% | 63.4% |
| 3684136 | 604.1.1.154 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 | 0.64 | 49.0 | 5.05e-01 | 81.6% | 98.2% |
| 3689721 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.62 | 52.0 | 4.77e-01 | 96.5% | 69.3% |
| 3709319 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 52.0 | 3.60e-01 | 93.9% | 27.5% |
| 4014703 | 109.4.1.156 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UNC45-central | 0.62 | 56.0 | 3.43e-01 | 99.1% | 21.0% |
| 3894828 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.61 | 53.0 | 4.88e-01 | 94.7% | 74.5% |
| 3783990 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 51.0 | 3.35e-01 | 92.1% | 25.1% |
| 434095 | 109.4.1.1501 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, TIP120, HEAT_EZ, HEAT_GCN1, TPR_CAND1 | 0.61 | 43.0 | 3.16e-01 | 92.1% | 27.5% |
| 3862009 | 3755.3.1.293 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH | 0.60 | 47.0 | 4.24e-01 | 83.3% | 94.4% |
| 3471712 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.60 | 46.0 | 4.51e-01 | 81.6% | 92.8% |
| 4458853 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.59 | 45.0 | 4.19e-01 | 100.0% | 64.1% |
| 4020710 | 3924.1.1.1 ↗ | alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Fungal_trans_2 | 0.59 | 50.0 | 3.41e-01 | 91.2% | 26.4% |
| 3783247 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 52.0 | 4.09e-01 | 97.4% | 53.3% |
| 3217073 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 53.0 | 4.41e-01 | 100.0% | 64.0% |
| 3417339 | 633.23.1.32 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom | 0.58 | 44.0 | 3.97e-01 | 81.6% | 66.7% |
| 3270156 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 47.0 | 3.98e-01 | 98.2% | 52.6% |
| 4189563 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.58 | 34.0 | 3.76e-01 | 79.8% | 71.9% |
| 3809724 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 44.0 | 4.12e-01 | 79.8% | 70.0% |
| 3228513 | 109.4.1.163 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N | 0.56 | 49.0 | 3.25e-01 | 95.6% | 62.2% |
| 4049578 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.56 | 32.0 | 3.56e-01 | 78.1% | 70.5% |
| 3707261 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 45.0 | 4.38e-01 | 88.6% | 96.2% |
| 3621307 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.56 | 42.0 | 3.73e-01 | 78.9% | 75.2% |
| 5065130 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.56 | 32.0 | 3.58e-01 | 77.2% | 72.9% |
| 3651260 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 47.0 | 3.88e-01 | 95.6% | 78.2% |
| 4281149 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.54 | 32.0 | 3.42e-01 | 78.1% | 66.3% |
| 3401137 | 207.1.1.104 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_Zer-1 | 0.54 | 47.0 | 3.10e-01 | 94.7% | 70.5% |
| 4944961 | 4121.1.1.19 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF27230 | 0.54 | 42.0 | 2.99e-01 | 84.2% | 59.5% |
| 4088407 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.54 | 41.0 | 3.46e-01 | 81.6% | 83.5% |
| 2895324 | 109.4.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm,Arm_3 | 0.53 | 49.0 | 3.22e-01 | 99.1% | 26.7% |
| 3649823 | 601.1.1.38 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › mTOR_dom | 0.53 | 47.0 | 4.05e-01 | 99.1% | 68.1% |
| 3971557 | 628.1.1.0 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain | 0.53 | 39.0 | 3.63e-01 | 76.3% | 79.3% |
| 3909938 | 101.1.1.65 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_4 | 0.51 | 36.0 | 3.92e-01 | 73.7% | 92.2% |
| 3785509 | 101.1.2.113 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNase_H2-Ydr279 | 0.50 | 39.0 | 3.37e-01 | 87.7% | 90.2% |
D2
medium
residues 1-92
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.75 | 62.0 | 5.46e-01 | 89.1% | 64.9% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.72 | 52.0 | 5.33e-01 | 88.0% | 79.3% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.70 | 54.0 | 5.60e-01 | 88.0% | 89.7% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.69 | 56.0 | 5.78e-01 | 89.1% | 97.7% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 56.0 | 4.40e-01 | 91.3% | 89.1% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.67 | 54.0 | 5.03e-01 | 87.0% | 74.8% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.66 | 54.0 | 4.49e-01 | 89.1% | 55.2% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.66 | 53.0 | 4.50e-01 | 87.0% | 57.0% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 45.0 | 4.23e-01 | 70.7% | 63.4% |
| 3op0A01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.65 | 54.0 | 4.83e-01 | 93.5% | 72.8% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 51.0 | 4.45e-01 | 87.0% | 89.7% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 52.0 | 5.06e-01 | 90.2% | 95.2% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.64 | 53.0 | 4.52e-01 | 93.5% | 87.9% |
| 8h72B01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 53.0 | 3.69e-01 | 92.4% | 87.5% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.62 | 48.0 | 4.58e-01 | 82.6% | 71.0% |
| 6humG01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.62 | 42.0 | 3.54e-01 | 72.8% | 40.0% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.62 | 48.0 | 4.58e-01 | 89.1% | 72.2% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.57 | 44.0 | 4.29e-01 | 83.7% | 82.9% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 46.0 | 3.65e-01 | 94.6% | 83.6% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.54 | 41.0 | 4.21e-01 | 84.8% | 83.0% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 43.0 | 4.28e-01 | 93.5% | 83.5% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.52 | 43.0 | 4.47e-01 | 90.2% | 93.1% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 40.0 | 3.76e-01 | 85.9% | 90.1% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3449442 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.73 | 60.0 | 5.73e-01 | 88.0% | 95.2% |
| 5029781 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.71 | 59.0 | 5.67e-01 | 90.2% | 98.1% |
| 4119921 | 1128.1.1.23 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Ycf66_N | 0.71 | 60.0 | 5.98e-01 | 91.3% | 92.6% |
| 5073702 | 633.29.1.13 ↗ | alpha bundles › Bromodomain-like › Putative uncharacterized protein PAV1-137 › Putative uncharacterized protein PAV1-137 › DUF2096_N | 0.70 | 57.0 | 5.60e-01 | 88.0% | 82.0% |
| 3725482 | 601.16.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase | 0.69 | 55.0 | 5.05e-01 | 85.9% | 70.0% |
| 3715110 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.68 | 60.0 | 5.81e-01 | 93.5% | 98.0% |
| 3783690 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.68 | 55.0 | 3.52e-01 | 90.2% | 18.1% |
| 4028424 | 1128.1.1.11 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Microp_apicomplexa_7 | 0.67 | 56.0 | 5.78e-01 | 96.7% | 97.6% |
| 3675831 | 601.7.1.35 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › UFL1_C | 0.67 | 49.0 | 4.31e-01 | 76.1% | 83.7% |
| 3316418 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.66 | 55.0 | 4.77e-01 | 92.4% | 76.6% |
| 4016292 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.65 | 48.0 | 4.26e-01 | 78.3% | 100.0% |
| 4028519 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.65 | 51.0 | 4.97e-01 | 88.0% | 78.0% |
| 3998827 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.65 | 51.0 | 5.27e-01 | 95.7% | 92.9% |
| 3309329 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.64 | 51.0 | 3.87e-01 | 85.9% | 50.9% |
| 3303117 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.64 | 53.0 | 5.54e-01 | 90.2% | 97.6% |
| 3796544 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.64 | 52.0 | 3.84e-01 | 90.2% | 78.0% |
| 3283506 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 49.0 | 4.77e-01 | 85.9% | 84.8% |
| 3498285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 51.0 | 4.51e-01 | 91.3% | 73.6% |
| 5075517 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.62 | 47.0 | 4.09e-01 | 82.6% | 58.1% |
| 4012069 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 47.0 | 3.93e-01 | 81.5% | 87.5% |
| 3959665 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.62 | 50.0 | 5.00e-01 | 89.1% | 92.6% |
| 3871867 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.61 | 48.0 | 4.26e-01 | 87.0% | 65.0% |
| 3739959 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 45.0 | 3.60e-01 | 79.3% | 96.8% |
| 3593000 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.60 | 49.0 | 5.07e-01 | 90.2% | 98.8% |
| 4007860 | 601.4.1.81 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › SirB | 0.60 | 46.0 | 4.28e-01 | 83.7% | 86.7% |
| 3277363 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.60 | 47.0 | 4.15e-01 | 84.8% | 80.0% |
| 4980515 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.59 | 42.0 | 3.49e-01 | 75.0% | 58.8% |
| 5063587 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.57 | 42.0 | 4.35e-01 | 77.2% | 94.1% |
| 3245015 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.56 | 43.0 | 4.54e-01 | 81.5% | 95.0% |
| 3621508 | 5050.1.1.31 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › SLC52_ribofla_tr | 0.56 | 46.0 | 3.76e-01 | 91.3% | 90.0% |
| 4456090 | 5086.1.1.94 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD | 0.55 | 40.0 | 3.09e-01 | 77.2% | 31.6% |
| 3784297 | 7087.1.1.1 ↗ | alpha bundles › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › Emopamil binding protein (EBP) transmembrane domain › EBP | 0.54 | 45.0 | 3.73e-01 | 90.2% | 72.1% |
| 4995445 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 42.0 | 3.38e-01 | 87.0% | 83.6% |
| 3739248 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 43.0 | 3.41e-01 | 89.1% | 82.9% |
| 55069 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.53 | 45.0 | 4.30e-01 | 93.5% | 94.5% |
| 4957637 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.52 | 43.0 | 4.37e-01 | 90.2% | 92.2% |
D3
medium
residues 249-389
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.58 | 35.0 | 3.49e-01 | 83.7% | 55.2% |
| 1wncB00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.52 | 25.0 | 3.25e-01 | 73.8% | 79.0% |
| 3ilkA02 | 1.10.8.590 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.52 | 27.0 | 3.57e-01 | 86.5% | 100.0% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4952974 | 7011.1.1.5 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O_anti_polymase | 0.79 | 50.0 | 3.96e-01 | 90.1% | 33.3% |
| 4953910 | 7011.1.1.5 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O_anti_polymase | 0.74 | 62.0 | 4.50e-01 | 92.9% | 34.9% |
| 4941766 | 7011.1.1.5 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O_anti_polymase | 0.73 | 59.0 | 4.20e-01 | 92.2% | 31.1% |
| 3987178 | 7011.1.1.3 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O-ag_pol_Wzy | 0.72 | 65.0 | 4.49e-01 | 97.9% | 35.7% |
| 4982721 | 7011.1.1.5 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › O_anti_polymase | 0.72 | 55.0 | 4.13e-01 | 95.7% | 34.2% |
| 4952342 | 7011.1.1.0 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain | 0.65 | 55.0 | 4.19e-01 | 90.8% | 42.6% |
| 3587904 | 7011.1.1.0 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain | 0.56 | 46.0 | 3.38e-01 | 87.9% | 77.1% |
| 4968425 | 4009.1.1.1 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom | 0.54 | 27.0 | 3.58e-01 | 80.9% | 94.3% |
| 3506141 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.53 | 27.0 | 3.44e-01 | 80.1% | 91.4% |