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CAH04188.1
Arc-VirAJ783769__CAH04188.1__X__00005
Identity
- Accession:
- AJ783769 ↗
- Protein ID:
- CAH04188.1 ↗
- Kingdom:
- archaea
Quality
88.0
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-141
Domain cluster:
representative
CATH (75)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.79 | 61.0 | 6.55e-01 | 79.4% | 100.0% |
| 3d19B00 | 1.20.1260.120 | Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 | 0.78 | 64.0 | 5.17e-01 | 86.5% | 50.0% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.78 | 65.0 | 6.14e-01 | 89.4% | 75.2% |
| 4wpcA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.77 | 57.0 | 4.44e-01 | 75.9% | 80.2% |
| 1z23A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.77 | 57.0 | 5.44e-01 | 76.6% | 69.9% |
| 2jswA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.76 | 68.0 | 6.11e-01 | 95.7% | 78.3% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 61.0 | 6.61e-01 | 95.0% | 100.0% |
| 1u8vB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 67.0 | 5.78e-01 | 96.5% | 90.1% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.74 | 66.0 | 5.95e-01 | 96.5% | 77.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.74 | 67.0 | 6.47e-01 | 97.2% | 94.8% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 54.0 | 4.42e-01 | 75.2% | 81.6% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 52.0 | 4.23e-01 | 71.6% | 96.0% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.73 | 43.0 | 5.45e-01 | 97.2% | 96.5% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 60.0 | 6.11e-01 | 87.2% | 95.0% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.73 | 39.0 | 4.40e-01 | 95.7% | 66.7% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 56.0 | 5.63e-01 | 80.1% | 83.8% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 67.0 | 6.51e-01 | 98.6% | 98.7% |
| 8cdaB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 65.0 | 6.22e-01 | 95.7% | 99.4% |
| 1txdA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.73 | 63.0 | 5.33e-01 | 93.6% | 76.6% |
| 5iduC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.73 | 66.0 | 6.31e-01 | 97.2% | 90.6% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 65.0 | 6.30e-01 | 97.2% | 98.7% |
| 1ivhA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 62.0 | 6.28e-01 | 91.5% | 97.2% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 66.0 | 6.20e-01 | 98.6% | 97.7% |
| 2uxwA01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 66.0 | 5.95e-01 | 98.6% | 80.1% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 65.0 | 6.33e-01 | 97.9% | 99.4% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 53.0 | 4.58e-01 | 76.6% | 90.7% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 55.0 | 5.15e-01 | 93.6% | 66.3% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.71 | 53.0 | 5.32e-01 | 77.3% | 97.9% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 64.0 | 6.31e-01 | 97.9% | 98.0% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 50.0 | 4.29e-01 | 73.8% | 50.2% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.70 | 49.0 | 4.13e-01 | 71.6% | 97.5% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.69 | 40.0 | 4.89e-01 | 100.0% | 90.8% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.69 | 50.0 | 5.11e-01 | 75.2% | 95.7% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 51.0 | 5.15e-01 | 92.2% | 78.3% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 50.0 | 3.95e-01 | 76.6% | 97.2% |
| 1ki1B01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.67 | 61.0 | 5.47e-01 | 100.0% | 84.4% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.67 | 40.0 | 4.15e-01 | 98.6% | 62.4% |
| 2z0qA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.67 | 58.0 | 5.23e-01 | 94.3% | 80.8% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 55.0 | 5.44e-01 | 92.9% | 82.6% |
| 3qweA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 49.0 | 4.01e-01 | 76.6% | 88.1% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.66 | 39.0 | 5.02e-01 | 94.3% | 100.0% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 51.0 | 5.00e-01 | 89.4% | 75.3% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 46.0 | 3.66e-01 | 70.9% | 97.1% |
| 4cybD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 54.0 | 5.05e-01 | 91.5% | 71.3% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.65 | 50.0 | 4.32e-01 | 79.4% | 65.9% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 54.0 | 5.05e-01 | 92.2% | 71.5% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 48.0 | 3.87e-01 | 75.9% | 86.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 53.0 | 4.94e-01 | 91.5% | 69.7% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.64 | 47.0 | 4.29e-01 | 77.3% | 69.5% |
| 1by1A00 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.63 | 54.0 | 4.78e-01 | 93.6% | 76.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.63 | 54.0 | 4.88e-01 | 95.0% | 68.8% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 52.0 | 4.22e-01 | 87.2% | 80.6% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.63 | 45.0 | 4.19e-01 | 73.8% | 64.2% |
| 3d85C00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.63 | 42.0 | 4.34e-01 | 84.4% | 71.4% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 49.0 | 4.19e-01 | 83.0% | 82.9% |
| 6gyhA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 53.0 | 4.59e-01 | 92.9% | 87.1% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 41.0 | 4.96e-01 | 75.9% | 100.0% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.62 | 49.0 | 4.80e-01 | 85.8% | 77.2% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.60 | 42.0 | 4.12e-01 | 73.0% | 73.1% |
| 6i9kA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 49.0 | 3.86e-01 | 89.4% | 92.9% |
| 5unhA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 43.0 | 3.50e-01 | 75.2% | 50.2% |
| 4zudA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 49.0 | 4.07e-01 | 90.8% | 61.3% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.59 | 37.0 | 3.63e-01 | 85.1% | 57.6% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 55.0 | 4.88e-01 | 100.0% | 91.6% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 47.0 | 3.88e-01 | 90.1% | 91.3% |
| 3vw7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 50.0 | 4.04e-01 | 98.6% | 87.6% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 37.0 | 4.32e-01 | 74.5% | 96.0% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 48.0 | 3.83e-01 | 93.6% | 85.2% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 48.0 | 4.30e-01 | 96.5% | 100.0% |
| 3pf0A00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.55 | 49.0 | 3.78e-01 | 97.2% | 98.7% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 45.0 | 4.06e-01 | 87.9% | 82.3% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 45.0 | 3.72e-01 | 92.9% | 93.1% |
| 4h7nA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.53 | 44.0 | 3.57e-01 | 89.4% | 80.3% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 47.0 | 4.07e-01 | 100.0% | 84.2% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.51 | 43.0 | 3.99e-01 | 93.6% | 89.5% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3992687 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.83 | 78.0 | 6.80e-01 | 98.6% | 99.0% |
| 3365580 | 601.1.2.3 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C | 0.82 | 73.0 | 6.70e-01 | 93.6% | 74.7% |
| 3629560 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.81 | 73.0 | 7.10e-01 | 95.7% | 100.0% |
| 3799465 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.80 | 69.0 | 6.58e-01 | 90.8% | 100.0% |
| 3930618 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.80 | 70.0 | 7.07e-01 | 93.6% | 100.0% |
| 4213065 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.79 | 73.0 | 7.03e-01 | 99.3% | 95.6% |
| 3999152 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.78 | 66.0 | 7.01e-01 | 92.9% | 100.0% |
| 3662019 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.78 | 56.0 | 5.55e-01 | 73.8% | 83.4% |
| 5035275 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.77 | 55.0 | 6.24e-01 | 74.5% | 97.1% |
| 3543797 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.77 | 70.0 | 6.21e-01 | 97.9% | 97.5% |
| 3617266 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.76 | 55.0 | 5.90e-01 | 74.5% | 93.3% |
| 3399721 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 68.0 | 6.72e-01 | 96.5% | 96.7% |
| 3689700 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.76 | 67.0 | 6.26e-01 | 94.3% | 92.9% |
| 4944388 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.75 | 54.0 | 4.97e-01 | 73.8% | 66.7% |
| 3192001 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.75 | 62.0 | 6.29e-01 | 87.2% | 100.0% |
| 3613946 | 1189.1.1.6 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ISG65-75 | 0.75 | 61.0 | 4.93e-01 | 84.4% | 97.6% |
| 3184336 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.75 | 66.0 | 6.42e-01 | 95.7% | 96.8% |
| 3677843 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.75 | 64.0 | 6.08e-01 | 95.0% | 78.5% |
| 3492547 | 601.15.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_N,PA28_C | 0.75 | 55.0 | 4.69e-01 | 75.2% | 75.8% |
| 4473674 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.74 | 53.0 | 5.86e-01 | 72.3% | 100.0% |
| 3619570 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.74 | 56.0 | 4.11e-01 | 78.7% | 92.8% |
| 3219809 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.74 | 53.0 | 5.89e-01 | 73.0% | 95.5% |
| 2326778 | 601.15.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_N,PA28_C | 0.74 | 54.0 | 4.67e-01 | 75.2% | 79.1% |
| 3868848 | 601.1.2.47 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MARVEL | 0.74 | 56.0 | 5.86e-01 | 79.4% | 100.0% |
| 3789005 | 150.1.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 | 0.74 | 65.0 | 6.04e-01 | 95.0% | 96.6% |
| 3784582 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.73 | 55.0 | 4.42e-01 | 76.6% | 85.1% |
| 3782069 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.73 | 59.0 | 6.00e-01 | 84.4% | 100.0% |
| 3394777 | 601.15.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_N,PA28_C | 0.73 | 54.0 | 4.42e-01 | 75.2% | 75.9% |
| 4928757 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.73 | 61.0 | 5.74e-01 | 89.4% | 81.8% |
| 4934024 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.73 | 61.0 | 5.67e-01 | 89.4% | 79.4% |
| 3266300 | 601.15.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C | 0.72 | 54.0 | 4.61e-01 | 76.6% | 72.1% |
| 3901994 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.72 | 59.0 | 6.16e-01 | 86.5% | 100.0% |
| 5031101 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.71 | 62.0 | 5.68e-01 | 92.9% | 79.4% |
| 3303028 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.71 | 62.0 | 6.03e-01 | 93.6% | 88.4% |
| 3629382 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.71 | 63.0 | 6.17e-01 | 96.5% | 96.0% |
| 3515526 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 62.0 | 6.31e-01 | 95.7% | 99.3% |
| 3991109 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.70 | 61.0 | 6.13e-01 | 92.9% | 98.6% |
| 3459387 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.70 | 57.0 | 5.28e-01 | 86.5% | 97.7% |
| 3509261 | 601.15.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C | 0.69 | 50.0 | 4.38e-01 | 74.5% | 71.2% |
| 3171827 | 192.29.1.4 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 | 0.69 | 45.0 | 4.64e-01 | 75.9% | 68.1% |
| 3339348 | 606.1.1.12 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Rx_N | 0.69 | 50.0 | 5.16e-01 | 73.8% | 97.7% |
| 5035441 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.69 | 49.0 | 3.28e-01 | 100.0% | 20.0% |
| 3408766 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.69 | 49.0 | 3.63e-01 | 72.3% | 70.4% |
| 3615404 | 1189.1.1.6 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › ISG65-75 | 0.69 | 59.0 | 4.56e-01 | 91.5% | 89.3% |
| 4018439 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.68 | 55.0 | 5.38e-01 | 85.8% | 100.0% |
| 3998378 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.68 | 48.0 | 3.62e-01 | 73.0% | 91.3% |
| 3241396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 59.0 | 5.74e-01 | 94.3% | 100.0% |
| 3234449 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.67 | 50.0 | 3.81e-01 | 77.3% | 92.7% |
| 4285185 | 5001.1.1.45 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra | 0.67 | 49.0 | 3.75e-01 | 75.2% | 90.9% |
| 3656227 | 633.7.1.0 ↗ | alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like | 0.67 | 56.0 | 5.78e-01 | 88.7% | 98.5% |
| 3373385 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.66 | 57.0 | 5.67e-01 | 92.2% | 100.0% |
| 3711206 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.66 | 61.0 | 5.04e-01 | 100.0% | 92.2% |
| 3931761 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.66 | 47.0 | 3.41e-01 | 73.8% | 84.8% |
| 3196018 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.65 | 57.0 | 4.57e-01 | 95.7% | 59.3% |
| 4956279 | 633.13.1.1 ↗ | alpha bundles › Bromodomain-like › DsbB-like › DsbB-like › DsbB | 0.65 | 56.0 | 5.62e-01 | 92.9% | 94.3% |
| 3919843 | 604.1.1.124 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 | 0.64 | 45.0 | 4.66e-01 | 70.9% | 100.0% |
| 3183672 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 57.0 | 5.65e-01 | 97.9% | 99.3% |
| 3488877 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 58.0 | 4.63e-01 | 100.0% | 76.3% |
| 3177832 | 174.1.1.62 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27705 | 0.63 | 57.0 | 5.51e-01 | 100.0% | 91.3% |
| 4950734 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.63 | 48.0 | 4.26e-01 | 100.0% | 58.4% |
| 3179894 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.61 | 53.0 | 5.26e-01 | 93.6% | 91.7% |
| 3235054 | 5001.1.1.45 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra | 0.60 | 50.0 | 4.07e-01 | 92.9% | 87.0% |
| 3232066 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 49.0 | 3.65e-01 | 90.1% | 74.9% |
| 3934651 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 54.0 | 4.33e-01 | 100.0% | 83.6% |
| 3505420 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 50.0 | 3.95e-01 | 93.6% | 83.0% |
| 3925622 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.59 | 43.0 | 3.56e-01 | 74.5% | 51.9% |
| 4223687 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.57 | 52.0 | 3.86e-01 | 100.0% | 57.5% |
| 3578012 | 109.3.1.325 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › ATP-synt_C | 0.57 | 48.0 | 3.82e-01 | 91.5% | 77.5% |
| 3489240 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 51.0 | 3.80e-01 | 100.0% | 62.7% |
| 3219312 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.55 | 49.0 | 3.62e-01 | 98.6% | 65.0% |
| 4663047 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 41.0 | 3.47e-01 | 100.0% | 48.9% |
| 3230039 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.54 | 48.0 | 3.68e-01 | 100.0% | 82.3% |
| 3238788 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.54 | 49.0 | 3.65e-01 | 100.0% | 82.0% |
| None | — | 0.52 | 44.0 | 3.57e-01 | 97.2% | 89.7% | |
| 3596737 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.51 | 38.0 | 3.97e-01 | 78.0% | 93.1% |
D2
medium
residues 142-168_272-307
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4y7dA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.59 | 43.0 | 2.77e-01 | 76.2% | 57.1% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.52 | 36.0 | 2.69e-01 | 71.4% | 72.3% |
| 4k7bA00 | 1.20.120.1740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sodium ion translocating NADH-quinone reductase subunit C-like | 0.52 | 40.0 | 3.34e-01 | 95.2% | 47.7% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.51 | 37.0 | 2.71e-01 | 77.8% | 68.0% |
| 2r7rA03 | 1.10.10.1990 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Viral RNA-directed RNA polymerase, 4-helical domain | 0.50 | 37.0 | 3.52e-01 | 98.4% | 65.8% |
D3
medium
residues 169-271
Domain cluster:
representative
CATH (53)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.79 | 68.0 | 6.54e-01 | 99.0% | 82.5% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.78 | 72.0 | 4.96e-01 | 100.0% | 81.8% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 54.0 | 6.20e-01 | 88.3% | 100.0% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 64.0 | 6.40e-01 | 90.3% | 93.3% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.76 | 60.0 | 5.19e-01 | 83.5% | 57.7% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.75 | 59.0 | 5.67e-01 | 91.3% | 72.9% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.75 | 62.0 | 6.12e-01 | 89.3% | 95.5% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.75 | 64.0 | 6.28e-01 | 100.0% | 86.4% |
| 1zbpA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.75 | 44.0 | 4.75e-01 | 87.4% | 69.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.75 | 61.0 | 5.84e-01 | 100.0% | 76.7% |
| 3vnxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 63.0 | 5.12e-01 | 92.2% | 76.9% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 64.0 | 5.46e-01 | 91.3% | 95.0% |
| 2c2uA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 64.0 | 5.35e-01 | 94.2% | 85.4% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 58.0 | 6.34e-01 | 98.1% | 100.0% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.74 | 52.0 | 5.90e-01 | 87.4% | 97.4% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.74 | 47.0 | 4.94e-01 | 78.6% | 71.0% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.74 | 61.0 | 6.34e-01 | 90.3% | 98.9% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.73 | 60.0 | 5.25e-01 | 88.3% | 90.8% |
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.73 | 49.0 | 5.71e-01 | 77.7% | 94.7% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.73 | 57.0 | 5.90e-01 | 84.5% | 93.8% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 59.0 | 5.72e-01 | 88.3% | 80.7% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 56.0 | 6.10e-01 | 100.0% | 100.0% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.71 | 59.0 | 5.81e-01 | 100.0% | 85.2% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 57.0 | 5.78e-01 | 87.4% | 98.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 60.0 | 5.05e-01 | 93.2% | 88.0% |
| 7tj9A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.70 | 53.0 | 5.30e-01 | 80.6% | 82.1% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.70 | 59.0 | 4.97e-01 | 91.3% | 81.7% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 54.0 | 5.49e-01 | 93.2% | 85.1% |
| 3llwD00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.69 | 60.0 | 4.29e-01 | 93.2% | 83.7% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 48.0 | 4.96e-01 | 98.1% | 76.3% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.69 | 56.0 | 4.31e-01 | 87.4% | 44.1% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 57.0 | 5.70e-01 | 91.3% | 98.1% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 57.0 | 5.63e-01 | 90.3% | 94.4% |
| 2xsbA02 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.68 | 59.0 | 5.21e-01 | 95.1% | 87.2% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 55.0 | 5.60e-01 | 99.0% | 89.1% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 55.0 | 5.61e-01 | 89.3% | 100.0% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.67 | 53.0 | 5.11e-01 | 86.4% | 76.7% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.66 | 53.0 | 5.02e-01 | 87.4% | 72.0% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.66 | 54.0 | 5.20e-01 | 88.3% | 79.0% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 5.39e-01 | 90.3% | 93.4% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.65 | 54.0 | 4.75e-01 | 90.3% | 94.0% |
| 7e84A02 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.64 | 54.0 | 4.97e-01 | 93.2% | 76.3% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 45.0 | 4.42e-01 | 88.3% | 67.3% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 52.0 | 4.60e-01 | 88.3% | 97.3% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 53.0 | 5.36e-01 | 91.3% | 95.1% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 52.0 | 4.89e-01 | 88.3% | 79.7% |
| 5gj7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 56.0 | 4.94e-01 | 99.0% | 78.1% |
| 4dlqA02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 42.0 | 4.40e-01 | 81.6% | 77.9% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.61 | 46.0 | 4.25e-01 | 79.6% | 93.9% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 44.0 | 4.62e-01 | 87.4% | 89.0% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.59 | 47.0 | 4.49e-01 | 87.4% | 74.0% |
| 1r3bA01 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.59 | 52.0 | 4.41e-01 | 100.0% | 72.4% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.55 | 45.0 | 4.14e-01 | 91.3% | 68.3% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3707377 | 604.12.1.73 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27107 | 0.88 | 73.0 | 6.81e-01 | 87.4% | 73.6% |
| 4863092 | 150.3.1.28 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › GCSF | 0.83 | 76.0 | 7.37e-01 | 100.0% | 87.7% |
| 4387552 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.81 | 64.0 | 7.04e-01 | 85.4% | 100.0% |
| 3194153 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 66.0 | 6.92e-01 | 88.3% | 100.0% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 66.0 | 5.79e-01 | 87.4% | 67.3% |
| 3894967 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.79 | 72.0 | 5.86e-01 | 99.0% | 92.4% |
| 3695367 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.78 | 67.0 | 5.21e-01 | 90.3% | 49.3% |
| 3221766 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.77 | 65.0 | 6.49e-01 | 90.3% | 91.4% |
| 3171689 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.77 | 65.0 | 6.19e-01 | 90.3% | 92.5% |
| 3757260 | 604.1.1.138 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › MNR | 0.77 | 65.0 | 5.50e-01 | 90.3% | 63.0% |
| 3938862 | 604.1.1.98 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 | 0.76 | 63.0 | 6.17e-01 | 88.3% | 85.5% |
| 3311612 | 109.4.1.1138 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SCAI | 0.76 | 61.0 | 4.83e-01 | 85.4% | 42.9% |
| 4992337 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.76 | 53.0 | 4.81e-01 | 70.9% | 88.9% |
| 3925622 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.76 | 63.0 | 4.81e-01 | 90.3% | 68.9% |
| 3587850 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.76 | 59.0 | 5.38e-01 | 84.5% | 74.3% |
| 5045256 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 62.0 | 6.47e-01 | 90.3% | 96.8% |
| 3721200 | 611.9.1.5 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › SesA | 0.75 | 54.0 | 5.01e-01 | 74.8% | 99.2% |
| 3612163 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.75 | 63.0 | 4.83e-01 | 91.3% | 88.5% |
| 4862444 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 68.0 | 6.17e-01 | 100.0% | 81.3% |
| 51377 | 5000.4.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain | 0.75 | 68.0 | 5.22e-01 | 100.0% | 56.8% |
| 4020294 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.74 | 63.0 | 4.85e-01 | 90.3% | 79.5% |
| 3473134 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.74 | 62.0 | 5.16e-01 | 89.3% | 59.4% |
| 3504305 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 61.0 | 6.11e-01 | 88.3% | 91.4% |
| 3322168 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.74 | 67.0 | 5.69e-01 | 100.0% | 61.2% |
| 3498232 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.74 | 62.0 | 5.07e-01 | 91.3% | 75.8% |
| 3303315 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.74 | 61.0 | 5.34e-01 | 91.3% | 60.7% |
| 4936980 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.74 | 66.0 | 6.39e-01 | 100.0% | 87.8% |
| 3391380 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.74 | 59.0 | 5.90e-01 | 86.4% | 88.6% |
| 3524429 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 60.0 | 6.16e-01 | 90.3% | 92.0% |
| 3401783 | 150.1.1.31 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety | 0.73 | 66.0 | 6.18e-01 | 100.0% | 84.0% |
| 3879044 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.73 | 67.0 | 6.25e-01 | 100.0% | 82.4% |
| 3883667 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 57.0 | 5.69e-01 | 83.5% | 100.0% |
| 4937575 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 58.0 | 6.15e-01 | 87.4% | 97.8% |
| 4022228 | 109.40.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › Ctf4_C | 0.72 | 55.0 | 4.81e-01 | 85.4% | 54.7% |
| 3769212 | 604.1.1.142 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SYNE1_2 | 0.72 | 60.0 | 5.85e-01 | 90.3% | 87.0% |
| 3497641 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.72 | 59.0 | 5.97e-01 | 88.3% | 100.0% |
| 3939260 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.72 | 59.0 | 6.03e-01 | 91.3% | 91.0% |
| 4014803 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.72 | 65.0 | 5.58e-01 | 100.0% | 70.6% |
| 3481122 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 59.0 | 6.01e-01 | 89.3% | 100.0% |
| 3787270 | 133.1.1.1 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF | 0.71 | 64.0 | 4.96e-01 | 100.0% | 65.2% |
| 3826671 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.71 | 58.0 | 4.69e-01 | 90.3% | 48.8% |
| 4025776 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 50.0 | 5.24e-01 | 74.8% | 88.4% |
| 3881582 | 310.2.1.31 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4455 | 0.70 | 55.0 | 5.54e-01 | 85.4% | 99.0% |
| 3901124 | 174.1.1.12 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › BCLP | 0.70 | 63.0 | 5.55e-01 | 100.0% | 86.7% |
| 3935032 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.69 | 57.0 | 5.67e-01 | 90.3% | 100.0% |
| 3287731 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 61.0 | 4.96e-01 | 98.1% | 72.5% |
| 4187493 | 603.1.1.103 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 | 0.68 | 56.0 | 5.04e-01 | 90.3% | 64.1% |
| 3631036 | 5069.1.1.38 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Frag1 | 0.67 | 60.0 | 5.02e-01 | 100.0% | 69.4% |
| 3190737 | 5001.1.1.115 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Frag1 | 0.66 | 60.0 | 4.65e-01 | 100.0% | 56.4% |
| 5016953 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.66 | 56.0 | 4.73e-01 | 89.3% | 74.4% |
| 2832541 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.65 | 57.0 | 4.53e-01 | 100.0% | 46.0% |
| 3226579 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.65 | 57.0 | 4.08e-01 | 96.1% | 75.7% |
| 3992612 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.65 | 52.0 | 5.46e-01 | 87.4% | 100.0% |
| 3516461 | 603.1.1.103 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732 | 0.64 | 51.0 | 5.04e-01 | 87.4% | 88.2% |
| 4176312 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.64 | 46.0 | 4.66e-01 | 73.8% | 96.0% |
| 3206688 | 604.1.1.135 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF155 | 0.64 | 56.0 | 4.07e-01 | 100.0% | 51.8% |
| 4628458 | 604.1.1.226 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26877 | 0.63 | 49.0 | 5.31e-01 | 98.1% | 100.0% |
| 4026440 | 5054.1.1.99 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TMEM33_Pom33 | 0.63 | 49.0 | 3.83e-01 | 85.4% | 38.2% |
| 3925930 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.62 | 52.0 | 5.28e-01 | 90.3% | 94.0% |
| 3471396 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.62 | 50.0 | 5.14e-01 | 88.3% | 95.8% |
| 3245526 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 51.0 | 5.13e-01 | 93.2% | 95.2% |
| 4991162 | 2484.1.1.302 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB | 0.61 | 51.0 | 4.07e-01 | 92.2% | 57.7% |
| 3285485 | 191.1.1.64 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › DUF4254 | 0.61 | 50.0 | 4.35e-01 | 88.3% | 65.2% |
| 3986636 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.59 | 53.0 | 4.30e-01 | 99.0% | 77.9% |
| 3169487 | 109.4.1.309 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med12 | 0.56 | 48.0 | 2.79e-01 | 95.1% | 19.1% |
| 3293442 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.56 | 48.0 | 3.83e-01 | 98.1% | 56.0% |