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AJ972879.2__CCE26352.1__X__00330

Bact-Vir

AJ972879.2__CCE26352.1__X__00330

Identity

Accession:
AJ972879 ↗
Kingdom:
phage

Quality

86.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 156-253
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6bq9A02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.90 70.0 7.16e-01 100.0% 84.0%
3lpxB02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.89 70.0 7.16e-01 100.0% 84.0%
3k59A02 3.30.70.2250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › B family DNA polymerase, N domain, alpha/beta motif 0.67 42.0 4.91e-01 88.8% 92.5%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 41.0 4.54e-01 87.8% 81.1%
2nyiA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 44.0 4.72e-01 88.8% 81.5%
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 48.0 5.06e-01 89.8% 84.3%
3wx4A00 3.30.70.2770 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 49.0 4.92e-01 89.8% 78.6%
2f1fA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.65 43.0 4.74e-01 88.8% 84.8%
4nohA01 3.30.70.3060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 40.0 4.56e-01 94.9% 85.9%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.64 46.0 4.64e-01 92.9% 75.0%
3g2fA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.64 45.0 4.81e-01 88.8% 82.8%
5qinA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.64 45.0 4.80e-01 87.8% 83.5%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 44.0 4.49e-01 88.8% 75.5%
2ofhX00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 41.0 4.60e-01 89.8% 93.0%
1pqxA00 3.30.1370.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Scaffold protein Nfu/NifU, N-terminal domain 0.62 48.0 5.03e-01 100.0% 89.0%
1d1rA00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.62 43.0 4.56e-01 100.0% 84.3%
1lk5A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 43.0 4.74e-01 93.9% 91.1%
2qmwA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 42.0 4.60e-01 88.8% 89.6%
1nh8A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 37.0 4.24e-01 88.8% 86.6%
3v2uC02 3.30.70.3170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 45.0 4.58e-01 89.8% 78.9%
1ygyA04 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 39.0 4.25e-01 89.8% 85.5%
3en9A03 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.59 42.0 4.79e-01 90.8% 100.0%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 43.0 4.38e-01 88.8% 77.6%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 46.0 4.62e-01 89.8% 83.7%
2od6C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 47.0 4.62e-01 88.8% 79.4%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 44.0 4.76e-01 90.8% 98.7%
2dkhA02 3.30.9.10 Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2 0.59 38.0 3.69e-01 88.8% 57.0%
5mmiU01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.58 43.0 4.69e-01 91.8% 93.9%
3kg0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 4.29e-01 88.8% 77.3%
4zosB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 4.31e-01 88.8% 78.4%
1sqeA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 43.0 4.32e-01 89.8% 76.2%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.58 41.0 4.31e-01 88.8% 84.1%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 4.30e-01 88.8% 79.2%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.58 40.0 4.45e-01 90.8% 96.0%
2d8iA01 2.30.42.10 Mainly Beta › Roll › Pdz3 Domain › PDZ domain 0.57 36.0 3.80e-01 99.0% 70.5%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 42.0 4.19e-01 88.8% 76.0%
3oksA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 43.0 3.63e-01 100.0% 45.5%
2bbeA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 42.0 4.19e-01 88.8% 75.7%
3kmuA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 38.0 4.03e-01 87.8% 78.2%
3n5mB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 45.0 3.76e-01 100.0% 48.3%
1zodA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 44.0 4.01e-01 100.0% 60.3%
4fh3A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.57 38.0 3.52e-01 75.5% 53.6%
1golA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 39.0 3.65e-01 87.8% 56.2%
3d3yA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 49.0 4.00e-01 98.0% 52.1%
1vq8S00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.56 41.0 4.40e-01 95.9% 93.8%
5vyeA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 36.0 3.65e-01 100.0% 64.7%
2op5B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 4.34e-01 88.8% 85.0%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.54 44.0 3.49e-01 90.8% 43.7%
3b8xA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 49.0 4.54e-01 100.0% 81.5%
3dxvA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 42.0 3.69e-01 100.0% 55.3%
1vdhA01 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.54 42.0 3.99e-01 89.8% 69.4%
3tu3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.52 41.0 3.94e-01 100.0% 73.1%
3pg1A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 40.0 3.67e-01 85.7% 63.6%
4h4kA01 3.30.70.2940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 36.0 3.77e-01 88.8% 82.0%
1vrmA01 3.10.520.10 Alpha Beta › Roll › T-fold › ApbE-like domains 0.51 29.0 2.33e-01 93.9% 25.0%
4nhxA01 2.60.120.620 Mainly Beta › Sandwich › Jelly Rolls › q2cbj1_9rhob like domain 0.51 39.0 3.06e-01 83.7% 83.3%
1s28A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.50 41.0 3.82e-01 96.9% 69.2%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4624017 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 72.0 5.67e-01 100.0% 43.3%
396210 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.92 75.0 5.39e-01 100.0% 34.6%
3962339 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.90 74.0 5.76e-01 100.0% 44.9%
2140592 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 70.0 5.50e-01 100.0% 43.4%
3590557 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.88 71.0 5.46e-01 100.0% 42.1%
4855517 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.86 70.0 5.17e-01 100.0% 36.7%
3965475 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 74.0 5.66e-01 100.0% 49.8%
4936431 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.75 49.0 5.45e-01 90.8% 86.7%
3958367 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.74 38.0 4.77e-01 74.5% 85.5%
3713128 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.74 48.0 5.53e-01 87.8% 91.4%
4024263 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.73 69.0 5.17e-01 100.0% 51.2%
4937285 304.128.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.71 51.0 5.18e-01 92.9% 75.8%
3614277 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.71 53.0 4.27e-01 100.0% 42.2%
4313857 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.69 44.0 4.99e-01 88.8% 88.6%
5066425 304.5.1.7 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.68 43.0 4.64e-01 88.8% 76.2%
3511024 304.28.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.68 51.0 5.09e-01 89.8% 76.0%
3996296 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.68 43.0 4.14e-01 90.8% 54.8%
4540833 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.67 49.0 5.21e-01 88.8% 88.2%
5037964 304.128.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.66 52.0 5.03e-01 93.9% 74.5%
4441813 4956.1.1.0 a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.65 47.0 4.97e-01 88.8% 85.9%
3988189 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 45.0 4.87e-01 90.8% 87.5%
4993405 304.8.1.2 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.65 42.0 4.65e-01 87.8% 85.3%
3386924 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 47.0 4.68e-01 100.0% 72.4%
5189 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 47.0 4.69e-01 89.8% 76.0%
4450606 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.63 47.0 5.01e-01 92.9% 89.4%
3329735 327.11.2.37 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_DEAH11_1st 0.62 41.0 4.64e-01 88.8% 95.7%
3664564 304.109.1.0 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e 0.61 37.0 4.52e-01 82.7% 100.0%
4958236 309.1.1.14 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › MZB 0.61 55.0 4.56e-01 100.0% 88.8%
3280383 327.16.1.4 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › YflT 0.61 41.0 4.67e-01 87.8% 100.0%
5049819 309.1.1.14 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › MZB 0.60 54.0 4.46e-01 100.0% 87.4%
5048300 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 40.0 3.96e-01 89.8% 63.8%
3970630 304.4.1.57 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MFS_3 0.59 45.0 4.34e-01 89.8% 71.8%
3847949 327.11.2.4 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › MOEP19 0.58 40.0 4.01e-01 89.8% 67.6%
3967172 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.58 51.0 4.16e-01 99.0% 51.4%
4029490 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.58 53.0 4.01e-01 100.0% 69.3%
4169399 304.14.1.1 a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.58 42.0 4.56e-01 88.8% 94.9%
3612606 304.20.1.0 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.58 50.0 4.84e-01 93.9% 93.6%
4355203 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.58 52.0 4.03e-01 100.0% 59.5%
None 0.57 52.0 2.94e-01 100.0% 14.9%
4395587 206.1.1.98 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1, APH 0.57 52.0 4.06e-01 100.0% 62.4%
4928432 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.57 42.0 4.25e-01 88.8% 80.0%
5082696 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.57 52.0 4.06e-01 100.0% 67.0%
5022581 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.57 52.0 4.07e-01 100.0% 64.5%
4234613 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.57 51.0 4.04e-01 100.0% 63.5%
3513343 304.109.1.2 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e › Ribosomal_L23,Ribosomal_L23eN 0.57 42.0 4.01e-01 96.9% 65.8%
5079337 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 50.0 3.52e-01 100.0% 45.2%
5052115 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 42.0 4.39e-01 88.8% 90.0%
3643481 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.55 50.0 3.33e-01 100.0% 43.2%
3424312 206.1.1.74 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.55 49.0 3.54e-01 100.0% 40.1%
4943533 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.55 42.0 3.66e-01 84.7% 62.5%
3610776 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.54 47.0 3.46e-01 98.0% 64.3%
3702551 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.54 48.0 3.24e-01 100.0% 43.1%
3968919 304.4.1.57 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MFS_3 0.54 45.0 4.19e-01 95.9% 72.0%
5035978 206.1.1.9 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.54 48.0 3.83e-01 100.0% 68.0%
4410192 304.102.1.4 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruB_N 0.54 46.0 3.47e-01 95.9% 60.0%
3775073 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.53 46.0 3.47e-01 98.0% 53.1%
5010455 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 47.0 3.67e-01 99.0% 60.3%
3614830 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.53 47.0 3.38e-01 99.0% 53.8%
3976466 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.53 41.0 3.62e-01 84.7% 58.7%
3720011 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 45.0 3.16e-01 98.0% 46.6%
3589979 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.52 40.0 3.88e-01 82.7% 87.3%
4061533 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.51 40.0 3.45e-01 84.7% 60.6%
4028769 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.51 46.0 3.71e-01 100.0% 62.6%
5047357 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.51 40.0 3.46e-01 84.7% 59.4%
4973784 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.51 41.0 2.71e-01 85.7% 32.1%
3811471 2003.1.2.34 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Prenylcys_lyase 0.51 36.0 3.76e-01 89.8% 81.1%
5007985 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 39.0 3.47e-01 84.7% 56.9%
4943593 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.50 40.0 3.60e-01 86.7% 87.9%
3966778 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.50 40.0 3.34e-01 86.7% 82.9%
4319179 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 39.0 3.36e-01 84.7% 58.1%
3611249 230.4.1.0 a+b two layers › T-fold › ApbE-like › ApbE-like 0.50 38.0 3.15e-01 100.0% 43.2%
4996837 225.1.1.3 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.50 39.0 3.32e-01 85.7% 51.8%
D2 medium residues 79-154_254-315
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 46.7 3.00e-12 65.2% 19.0%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xcqA02 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.92 68.0 5.21e-01 87.7% 38.4%
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.84 51.0 4.09e-01 85.5% 33.7%
1kv9A02 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.52 32.0 3.64e-01 73.2% 81.6%
1jgsA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 31.0 3.16e-01 90.6% 61.6%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3965475 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.94 65.0 5.50e-01 70.3% 98.5%
4024263 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.94 65.0 5.44e-01 71.0% 98.1%
3590557 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 65.0 5.65e-01 71.7% 93.3%
4855517 101.1.2.9 alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.87 60.0 4.93e-01 70.3% 77.4%
3998667 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.78 64.0 5.63e-01 86.2% 98.5%
3614277 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.77 55.0 4.98e-01 73.9% 93.3%
3220665 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 53.0 4.80e-01 71.0% 97.7%
3719735 4014.1.1.1 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 52.0 4.86e-01 71.7% 99.4%
3789606 4014.1.1.0 a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.73 50.0 4.65e-01 70.3% 97.6%
4618205 604.1.1.150 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28954 0.59 31.0 3.30e-01 74.6% 58.3%
4937431 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 41.0 3.87e-01 81.9% 73.9%
D3 medium residues 428-542
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1suuA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.81 63.0 4.57e-01 93.9% 32.1%
3l6vA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.72 61.0 4.34e-01 94.8% 32.6%
3uc1A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.72 59.0 4.26e-01 93.9% 33.0%
1wp5A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.68 54.0 3.88e-01 93.9% 30.1%
2yn5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 35.0 4.17e-01 93.0% 81.0%
3no0A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.60 51.0 3.88e-01 93.9% 54.0%
1hskA01 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.52 33.0 3.25e-01 93.9% 58.3%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4429482 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.82 73.0 5.09e-01 100.0% 32.2%
4589818 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.82 70.0 4.97e-01 95.7% 33.8%
4602375 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 72.0 4.96e-01 100.0% 30.9%
5040277 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 73.0 5.09e-01 100.0% 33.5%
5053478 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 72.0 5.08e-01 100.0% 34.3%
4102294 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 72.0 5.08e-01 100.0% 34.3%
3959000 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.80 72.0 5.73e-01 100.0% 51.7%
5082153 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.80 68.0 4.83e-01 93.9% 32.9%
4261933 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.80 72.0 5.04e-01 100.0% 33.8%
4075947 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.80 65.0 5.00e-01 99.1% 41.3%
3445642 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.80 71.0 4.92e-01 100.0% 31.3%
4331124 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.80 71.0 4.83e-01 100.0% 29.6%
4271590 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.79 71.0 5.01e-01 100.0% 34.1%
4279289 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.79 70.0 4.91e-01 100.0% 33.2%
4505869 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.78 70.0 4.93e-01 100.0% 34.3%
4186650 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.77 66.0 4.70e-01 96.5% 33.1%
4074611 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.76 65.0 4.64e-01 95.7% 33.1%
4935505 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.76 65.0 4.63e-01 95.7% 33.8%
4493828 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.76 60.0 4.36e-01 93.9% 32.8%
4606923 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.76 67.0 4.67e-01 100.0% 32.4%
4388717 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.75 67.0 4.74e-01 100.0% 34.3%
4946214 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.74 65.0 4.61e-01 100.0% 32.9%
4150603 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.74 64.0 4.57e-01 96.5% 33.1%
5007962 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.73 62.0 4.56e-01 97.4% 36.2%
4250515 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.72 57.0 4.40e-01 94.8% 39.1%
3164811 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.70 59.0 4.45e-01 93.9% 40.0%
5024979 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.70 56.0 4.08e-01 93.9% 31.9%
5059693 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.69 58.0 4.25e-01 94.8% 34.3%
4177906 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.68 57.0 4.10e-01 94.8% 32.9%
2179 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.68 54.0 3.88e-01 93.9% 30.0%
4410663 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.67 53.0 4.16e-01 93.9% 40.0%
4214118 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.66 52.0 3.91e-01 93.9% 34.4%
4609257 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.64 52.0 3.74e-01 93.9% 30.6%
4569696 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.62 56.0 4.03e-01 99.1% 88.4%
3969629 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.61 54.0 4.15e-01 95.7% 56.5%
4128974 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.54 33.0 3.93e-01 75.7% 90.0%
D4 medium residues 543-646
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03989.19 best DNA_gyraseA_C 20.2 4.40e-04 46.2% 95.8%
PF03989.19 DNA_gyraseA_C 26.6 4.30e-06 43.3% 89.6%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l6vA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.92 88.0 6.00e-01 100.0% 33.2%
3no0A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.90 84.0 5.91e-01 100.0% 36.6%
3uc1A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.90 86.0 5.93e-01 100.0% 35.0%
1wp5A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.89 85.0 5.76e-01 100.0% 32.6%
1suuA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.88 84.0 5.84e-01 100.0% 48.1%
2yn5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.65 40.0 4.59e-01 94.2% 83.5%
5mj6A03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 44.0 4.96e-01 93.3% 92.5%
1i9gA01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.63 35.0 4.18e-01 87.5% 84.4%
1qr4A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 40.0 4.31e-01 97.1% 85.1%
3mb5A01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.59 32.0 3.80e-01 87.5% 83.9%
5owvD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 36.0 2.86e-01 99.0% 29.3%
3dlqR02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 41.0 4.24e-01 94.2% 78.0%
6m3aA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 32.0 3.86e-01 93.3% 84.8%
1ca1A02 2.60.60.20 Mainly Beta › Sandwich › Lipoxygenase-1 › PLAT/LH2 domain 0.55 38.0 3.67e-01 86.5% 61.7%
3hu1A01 2.40.40.20 Mainly Beta › Beta Barrel › Barwin-like endoglucanases › 0.54 41.0 4.29e-01 92.3% 88.5%
1x4zA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 37.0 3.79e-01 93.3% 77.0%
1g2rA00 3.30.1230.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › YlxR-like 0.51 36.0 3.81e-01 74.0% 81.9%
2gqtA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.50 37.0 3.57e-01 100.0% 66.9%
1yn3A00 3.10.20.120 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 36.0 3.75e-01 90.4% 79.6%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4569696 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.95 91.0 6.15e-01 100.0% 32.8%
4186650 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.94 90.0 6.08e-01 100.0% 32.8%
4606923 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 89.0 5.97e-01 100.0% 31.2%
4946214 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 89.0 6.03e-01 100.0% 32.6%
4150603 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 89.0 6.03e-01 100.0% 32.8%
4331124 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 89.0 5.84e-01 100.0% 29.0%
4279289 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 88.0 5.94e-01 100.0% 31.7%
4074611 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 88.0 5.99e-01 100.0% 32.8%
4935505 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 89.0 6.08e-01 100.0% 49.8%
4271590 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 89.0 6.00e-01 100.0% 32.8%
3445642 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 5.87e-01 100.0% 30.1%
5040277 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 5.95e-01 100.0% 47.1%
4429482 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 5.91e-01 100.0% 35.2%
5024979 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 87.0 5.96e-01 100.0% 33.2%
4388717 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 87.0 5.94e-01 100.0% 32.7%
4602375 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 5.84e-01 100.0% 30.3%
5059693 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 6.06e-01 100.0% 36.7%
5007962 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 84.0 5.82e-01 95.2% 35.5%
4589818 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 6.03e-01 100.0% 34.1%
4261933 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 88.0 5.95e-01 100.0% 32.5%
5053478 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 87.0 5.93e-01 100.0% 33.0%
4505869 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 86.0 5.89e-01 100.0% 48.6%
5082153 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.90 86.0 5.92e-01 100.0% 33.5%
4102294 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 86.0 5.86e-01 100.0% 47.6%
4214118 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 84.0 5.92e-01 100.0% 36.6%
4177906 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.89 85.0 5.83e-01 100.0% 38.4%
2179 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.89 85.0 5.76e-01 100.0% 32.5%
4493828 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.89 84.0 5.91e-01 100.0% 35.9%
4421198 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.88 83.0 6.48e-01 100.0% 72.2%
4028934 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 84.0 5.79e-01 100.0% 49.2%
4609257 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 83.0 5.63e-01 100.0% 46.6%
4410663 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 78.0 5.77e-01 100.0% 40.8%
4075947 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.86 77.0 5.78e-01 100.0% 42.1%
3959000 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.85 76.0 5.93e-01 95.2% 49.3%
3969629 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.84 79.0 5.77e-01 100.0% 62.4%
3164811 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.83 77.0 5.65e-01 100.0% 62.0%
4250515 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.82 76.0 5.58e-01 99.0% 42.3%
2526350 1.17.1.0 beta barrels › cradle loop barrel 0.65 44.0 5.09e-01 92.3% 96.1%
3943690 11.1.4.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.65 36.0 4.54e-01 84.6% 96.6%
3561485 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 40.0 4.36e-01 97.1% 82.4%
3885093 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.59 41.0 4.47e-01 100.0% 89.4%
1479 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.59 40.0 4.31e-01 97.1% 85.1%
3888090 11.1.1.794 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › LIFR_D4 0.58 41.0 4.33e-01 97.1% 83.3%
3935844 5.1.3.204 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF7911 0.58 52.0 3.68e-01 100.0% 88.6%
5034410 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 4.28e-01 100.0% 84.0%
5033341 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 32.0 3.34e-01 94.2% 61.0%
2709685 221.1.1.17 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Stap_Strp_tox_C 0.51 37.0 3.69e-01 90.4% 72.9%
5013637 221.1.3.1 a+b two layers › beta-Grasp › Ubiquitin-related › Sulfite oxidase, middle catalytic domain › Oxidored_molyb 0.51 41.0 3.55e-01 87.5% 93.3%
4033546 221.1.1.20 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › MAP 0.50 36.0 3.58e-01 90.4% 70.9%
D5 medium residues 647-749
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03989.19 best DNA_gyraseA_C 28.7 9.80e-07 49.5% 97.9%
PF03989.19 DNA_gyraseA_C 13.5 5.50e-02 46.6% 79.2%
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3no0A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.90 81.0 5.70e-01 100.0% 35.1%
1suuA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.90 84.0 5.82e-01 100.0% 34.5%
3l6vA00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.89 84.0 5.73e-01 100.0% 32.6%
3uc1A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.88 84.0 5.78e-01 100.0% 34.7%
1wp5A00 2.120.10.90 Mainly Beta › 6 Propeller › Neuraminidase › DNA gyrase/topoisomerase IV, subunit A, C-terminal 0.87 83.0 5.63e-01 100.0% 32.3%
1i9gA01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.66 36.0 4.37e-01 92.2% 84.4%
1o54A01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.64 35.0 4.10e-01 92.2% 75.0%
5mj6A03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 44.0 4.85e-01 99.0% 92.5%
2yn5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 39.0 4.37e-01 99.0% 87.3%
2dlgA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 36.0 3.93e-01 92.2% 82.5%
1qr4A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 4.13e-01 99.0% 87.4%
4he6A00 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.54 40.0 4.30e-01 95.1% 91.0%
1wzoB02 3.90.850.10 Alpha Beta › Alpha-Beta Complex › Fumarylacetoacetate hydrolase; domain 2 › Fumarylacetoacetase-like, C-terminal domain 0.54 44.0 3.65e-01 91.3% 78.8%
1g2rA00 3.30.1230.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › YlxR-like 0.53 34.0 3.54e-01 74.8% 70.2%
3dlqR02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 3.96e-01 99.0% 78.0%
1o5uA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.53 31.0 3.37e-01 98.1% 67.0%
2waaA01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 38.0 3.58e-01 99.0% 64.2%
1hskA01 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.51 35.0 3.29e-01 100.0% 56.7%
1a21B02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 36.0 3.75e-01 96.1% 78.6%
4pytA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.50 35.0 3.33e-01 100.0% 57.8%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4935505 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.94 87.0 5.93e-01 100.0% 32.5%
4186650 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 88.0 5.95e-01 100.0% 32.2%
4388717 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.93 88.0 5.93e-01 100.0% 32.1%
5053478 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 89.0 6.01e-01 100.0% 32.7%
4589818 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 86.0 5.88e-01 99.0% 32.8%
4279289 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 87.0 5.84e-01 100.0% 31.1%
5082153 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.92 88.0 5.96e-01 100.0% 32.9%
4569696 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 87.0 5.84e-01 100.0% 31.6%
4261933 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.92 87.0 5.89e-01 100.0% 31.9%
4150603 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 87.0 5.87e-01 100.0% 31.9%
4214118 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 84.0 5.89e-01 100.0% 35.5%
5024979 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 85.0 5.77e-01 100.0% 32.3%
4074611 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 86.0 5.85e-01 100.0% 32.5%
4102294 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 86.0 5.85e-01 100.0% 32.4%
5040277 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 87.0 5.85e-01 100.0% 33.5%
4606923 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.91 87.0 5.83e-01 100.0% 31.8%
4602375 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 87.0 5.74e-01 100.0% 37.4%
4429482 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 85.0 5.68e-01 99.0% 30.1%
3445642 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 86.0 5.74e-01 100.0% 35.4%
4331124 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 86.0 5.64e-01 100.0% 41.4%
4493828 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 83.0 5.74e-01 100.0% 34.1%
4946214 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 86.0 5.80e-01 100.0% 32.9%
4177906 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 85.0 5.84e-01 100.0% 33.5%
4505869 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 84.0 5.71e-01 100.0% 32.1%
4271590 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.90 86.0 5.80e-01 100.0% 33.8%
5059693 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.89 85.0 5.87e-01 100.0% 35.3%
4609257 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.88 82.0 5.56e-01 100.0% 31.2%
4421198 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.88 83.0 6.43e-01 100.0% 51.2%
5007962 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 82.0 5.72e-01 99.0% 35.9%
2179 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 83.0 5.62e-01 100.0% 32.2%
4075947 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 77.0 5.73e-01 100.0% 40.9%
4028934 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.87 81.0 5.62e-01 100.0% 34.2%
4410663 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.83 75.0 5.55e-01 100.0% 41.2%
4250515 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.82 77.0 5.64e-01 100.0% 42.3%
3969629 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 76.0 5.54e-01 100.0% 42.7%
3164811 5.2.1.1 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel › DNA_gyraseA_C 0.81 76.0 5.51e-01 100.0% 41.2%
3959000 5.2.1.0 beta duplicates or obligate multimers › beta-propeller-like › beta-pinwheel › beta-pinwheel 0.80 74.0 5.76e-01 100.0% 49.8%
4217174 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.57 36.0 4.16e-01 95.1% 92.9%
5034410 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 41.0 4.23e-01 100.0% 82.0%
3885093 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.55 39.0 4.21e-01 100.0% 90.6%
3560830 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.55 39.0 4.14e-01 100.0% 85.6%
3248572 72.1.1.0 beta sandwiches › gamma-Crystallin-like › gamma-Crystallin-like › gamma-Crystallin-like 0.54 40.0 4.47e-01 100.0% 100.0%
3528768 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.54 38.0 4.06e-01 100.0% 85.6%
3973332 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.53 35.0 3.96e-01 94.2% 92.0%
3893503 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.52 36.0 3.70e-01 99.0% 74.0%
5038807 2.10.1.1 beta barrels › OB-fold › CheW › CheW › CheW 0.51 38.0 3.48e-01 79.6% 92.1%