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ATP-dependent_DNA_ligase

Euk-Vir

Pithovirus_sibericum

ATP-dependent_DNA_ligase__YP_009001365__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001365 ↗
Protein ID:
ATP-dependent_DNA_ligase
Kingdom:
euk

Quality

75.2 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (52 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 354-433
PDB
Domain cluster: rep: MK256384.1__QBA85097.1__X__00002__D37-130
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14743.13 best DNA_ligase_OB_2 28.5 1.70e-06 86.2% 81.8%
D2 medium residues 54-157
PDB
Domain cluster: representative
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yemB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.66 43.0 3.65e-01 81.7% 41.0%
4ufcA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.59 50.0 3.55e-01 94.2% 85.3%
4ebrA00 3.30.1460.50 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.58 46.0 4.07e-01 86.5% 90.4%
2w38A01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.57 46.0 3.30e-01 87.5% 89.2%
5t5lA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 3.70e-01 91.3% 75.5%
2eigA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 47.0 3.70e-01 91.3% 77.4%
2joxA00 2.60.40.4240 Mainly Beta › Sandwich › Immunoglobulin-like › Transcription activator, Churchill 0.56 34.0 3.43e-01 72.1% 57.5%
2w5nA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.56 44.0 3.09e-01 85.6% 84.7%
2o62A01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 42.0 3.91e-01 78.8% 92.4%
2gfgA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.56 39.0 3.23e-01 74.0% 39.8%
1l3aA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.56 40.0 3.49e-01 76.9% 48.8%
4dokA01 3.50.70.10 Alpha Beta › 3-Layer(bba) Sandwich › Chalcone isomerase › 0.55 41.0 3.62e-01 78.8% 84.5%
6htnA01 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.55 46.0 4.16e-01 91.3% 67.9%
3kstA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 43.0 3.18e-01 86.5% 79.0%
5c0pA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 47.0 3.50e-01 99.0% 86.3%
3tdgA01 3.10.450.520 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 28.0 3.40e-01 87.5% 78.8%
1inyA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.53 47.0 3.17e-01 98.1% 43.3%
4ge1C00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.53 43.0 3.65e-01 94.2% 83.9%
5ay6A01 2.60.98.20 Mainly Beta › Sandwich › Tick-borne Encephalitis virus Glycoprotein; domain 1 › Flagellar hook protein FlgE 0.52 41.0 3.58e-01 86.5% 98.2%
3w9aA00 2.60.120.1160 Mainly Beta › Sandwich › Jelly Rolls › 0.52 43.0 3.36e-01 91.3% 59.5%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.52 36.0 4.06e-01 77.9% 96.2%
4hfsA00 2.60.120.1270 Mainly Beta › Sandwich › Jelly Rolls › 0.52 45.0 3.68e-01 99.0% 95.1%
3wjcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 39.0 3.56e-01 84.6% 92.8%
1egxA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 38.0 3.75e-01 79.8% 84.3%
2mdrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 38.0 4.02e-01 99.0% 87.2%
6nu7A01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.51 45.0 3.19e-01 100.0% 75.3%
3sreA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.51 42.0 2.99e-01 90.4% 64.7%
2eabB01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.51 44.0 3.36e-01 97.1% 96.4%
3eliA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 41.0 3.73e-01 90.4% 90.3%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.50 38.0 3.51e-01 99.0% 61.4%
1z94B00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 41.0 3.72e-01 90.4% 90.2%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3228242 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.72 60.0 6.11e-01 87.5% 94.0%
4988423 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.69 46.0 5.15e-01 79.8% 88.7%
3968468 4152.2.1.0 ↗ a+b two layers › Shew3726-like › Uncharacterized protein CV_2116 › Uncharacterized protein CV_2116 0.66 42.0 4.78e-01 71.2% 88.0%
3256023 4026.1.1.0 ↗ a+b three layers › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) 0.63 50.0 4.61e-01 84.6% 93.3%
4978599 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.62 49.0 3.34e-01 84.6% 89.9%
3216442 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.61 43.0 3.43e-01 89.4% 35.7%
3849839 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.61 46.0 4.71e-01 79.8% 91.0%
3226497 145.1.1.1 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › F-box 0.60 38.0 3.73e-01 94.2% 57.4%
4251420 5.1.4.40 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PQQ_2 0.60 47.0 3.05e-01 85.6% 68.6%
3443454 10.1.1.2 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB 0.59 49.0 3.74e-01 91.3% 72.0%
3497302 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.58 48.0 4.39e-01 90.4% 76.4%
3288281 881.1.1.15 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › DUF3558 0.58 39.0 3.56e-01 76.0% 50.0%
3394892 10.1.1.17 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.58 51.0 4.08e-01 98.1% 88.6%
4596967 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.57 48.0 3.70e-01 91.3% 76.4%
3450584 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.57 48.0 3.46e-01 92.3% 94.6%
4016261 5.1.2.8 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_43 0.57 45.0 3.22e-01 86.5% 84.2%
3340789 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.56 43.0 3.03e-01 83.7% 92.3%
853 9.1.1.23 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF3598_N 0.56 42.0 3.90e-01 78.8% 91.7%
5069442 5.1.2.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed 0.56 43.0 3.13e-01 81.7% 88.3%
3648057 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 47.0 3.26e-01 93.3% 93.9%
3663999 5.1.2.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed 0.55 50.0 3.45e-01 99.0% 65.0%
5058595 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.55 50.0 3.45e-01 99.0% 61.4%
3577440 719.1.1.0 ↗ beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain 0.55 46.0 4.49e-01 90.4% 87.8%
3924310 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.55 44.0 3.05e-01 87.5% 86.2%
3033584 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.54 44.0 3.78e-01 88.5% 90.0%
3397645 5.1.4.85 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › NOL11_N 0.54 46.0 3.27e-01 93.3% 84.7%
1564338 5.1.2.8 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_43 0.54 47.0 3.50e-01 99.0% 86.3%
3457581 5.1.3.68 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF1618 0.54 46.0 3.18e-01 94.2% 97.5%
5022885 5.1.4.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.54 48.0 3.14e-01 99.0% 39.3%
3575058 5.1.5.169 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › ELYS-bb 0.54 46.0 3.33e-01 92.3% 40.4%
3487292 5.1.4.34 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup88 0.54 43.0 2.70e-01 85.6% 84.0%
4599893 223.3.1.3 ↗ a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.54 40.0 3.00e-01 79.8% 67.5%
4996503 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.54 41.0 3.42e-01 82.7% 78.4%
3599742 5.1.5.12 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › FG-GAP_3 0.53 45.0 3.03e-01 93.3% 93.5%
3676182 5.1.2.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_32N 0.53 47.0 3.23e-01 98.1% 57.3%
4957722 71.1.1.0 ↗ beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB 0.53 43.0 3.91e-01 86.5% 97.1%
3769507 4.1.1.31 ↗ beta barrels › SH3 › SH3 › SH3 › Spin-Ssty 0.53 30.0 3.52e-01 89.4% 82.9%
4978809 7520.1.1.1 ↗ a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like › CinA 0.52 42.0 3.51e-01 86.5% 85.6%
3421020 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.52 46.0 3.64e-01 98.1% 89.1%
3383121 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.52 41.0 2.94e-01 84.6% 75.2%
3388799 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.51 39.0 3.25e-01 80.8% 70.8%
3607725 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.51 44.0 2.97e-01 95.2% 74.3%
3707788 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.51 45.0 3.49e-01 98.1% 82.2%
3364063 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.51 39.0 3.59e-01 97.1% 62.1%
3821398 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.51 40.0 2.87e-01 84.6% 95.1%
5081947 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.50 46.0 3.20e-01 100.0% 88.5%
3699834 9.2.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin 0.50 38.0 3.61e-01 81.7% 97.6%
D3 medium residues 158-330
PDB
Domain cluster: rep: Salt_Pond_R1_B_H2O_MG_scaffold_1_prodigal-single.1__X__X__00295__D161-347
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01068.27 best DNA_ligase_A_M 45.5 1.10e-11 98.8% 81.9%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6imjA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.90 85.0 8.25e-01 97.1% 91.0%
1fviA01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.89 29.0 4.52e-01 97.1% 69.6%
6rarI01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.88 83.0 7.90e-01 97.7% 93.3%
4d05A01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.87 28.0 4.40e-01 97.1% 69.7%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.87 82.0 7.71e-01 97.7% 90.5%
2hivA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.87 81.0 7.59e-01 97.7% 88.3%
6kduA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.79 75.0 6.50e-01 100.0% 87.3%
4glwA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.79 75.0 6.78e-01 100.0% 94.6%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.75 69.0 6.85e-01 97.7% 93.3%
1xk5A01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.73 65.0 6.17e-01 97.1% 80.4%
4ckbA01 3.30.470.140 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › 0.73 58.0 5.74e-01 97.7% 79.8%
4pz6A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.71 66.0 5.88e-01 97.7% 78.0%
3vnnA00 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.68 47.0 5.48e-01 85.0% 97.6%
2h1yA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.57 24.0 3.52e-01 87.3% 91.4%
1utaA00 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.52 26.0 3.53e-01 89.0% 100.0%
3w9iD03 3.30.70.1320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like 0.52 31.0 3.89e-01 95.4% 98.1%
ECOD (97)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3598802 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.92 87.0 7.23e-01 96.5% 87.7%
3715432 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.90 85.0 6.69e-01 97.7% 83.0%
3605538 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 85.0 7.16e-01 97.7% 81.9%
3599023 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.89 84.0 7.49e-01 97.7% 85.7%
4495705 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.89 84.0 7.52e-01 97.7% 89.3%
5036153 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 83.0 7.94e-01 97.7% 91.8%
2559783 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 83.0 7.79e-01 97.7% 90.5%
3947455 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 83.0 7.57e-01 97.7% 89.8%
4977191 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.87 82.0 7.53e-01 97.7% 84.7%
4325132 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.87 82.0 6.44e-01 98.3% 57.3%
4966636 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.87 82.0 7.56e-01 97.7% 87.1%
5039677 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 7.48e-01 98.3% 83.6%
4600922 4095.1.1.0 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain 0.87 82.0 5.95e-01 98.3% 43.3%
3602296 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 7.37e-01 97.7% 88.0%
4937749 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 6.38e-01 97.7% 55.5%
4935888 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 6.35e-01 97.7% 54.0%
4045857 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.87 82.0 5.92e-01 97.7% 43.8%
4982625 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 7.34e-01 97.7% 80.4%
3798407 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.87 81.0 7.46e-01 97.7% 86.0%
4473535 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.87 81.0 6.36e-01 97.7% 55.5%
4945406 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 81.0 7.53e-01 97.7% 86.7%
5083927 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 81.0 7.39e-01 97.7% 93.1%
4289141 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.86 81.0 5.88e-01 97.7% 42.4%
4399570 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 7.30e-01 97.7% 89.8%
5042001 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 6.37e-01 97.7% 56.0%
4947307 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 6.29e-01 97.7% 54.0%
1245394 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 79.0 7.61e-01 97.7% 86.2%
4213407 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.86 81.0 5.93e-01 97.7% 44.0%
5016269 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 6.23e-01 97.7% 56.8%
4098851 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.86 81.0 6.27e-01 97.7% 58.5%
4951306 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 5.87e-01 97.7% 41.9%
4056196 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.86 81.0 5.79e-01 98.3% 41.6%
3704759 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 80.0 7.03e-01 97.7% 77.9%
3315215 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 80.0 7.12e-01 97.7% 87.8%
5031580 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 80.0 7.58e-01 97.7% 88.5%
4666907 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 79.0 7.44e-01 97.1% 86.8%
3960632 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.85 80.0 7.49e-01 97.7% 86.8%
4631711 4095.1.1.3 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.85 80.0 5.94e-01 97.7% 46.8%
4683228 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.85 80.0 5.93e-01 97.7% 46.2%
4012824 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.85 81.0 7.14e-01 99.4% 88.5%
3643093 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 79.0 7.02e-01 97.7% 85.1%
3387834 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 78.0 7.64e-01 97.7% 89.7%
3182465 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 80.0 6.91e-01 99.4% 82.7%
4263845 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 79.0 7.07e-01 97.7% 85.7%
3476026 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 79.0 6.63e-01 98.3% 85.9%
2831771 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 73.0 7.19e-01 97.7% 84.9%
3922871 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 79.0 7.03e-01 97.7% 81.3%
4680450 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 79.0 7.24e-01 97.7% 89.8%
4000577 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 78.0 6.70e-01 97.1% 88.2%
3253455 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.84 78.0 5.58e-01 97.7% 43.3%
4237088 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 79.0 7.43e-01 97.7% 86.0%
4343302 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.83 78.0 5.59e-01 97.7% 42.9%
3968582 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 77.0 7.39e-01 97.7% 86.8%
3799247 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.83 78.0 6.64e-01 97.7% 70.0%
3281941 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 78.0 7.46e-01 97.7% 88.7%
4188682 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 78.0 6.69e-01 97.7% 82.7%
3378267 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.83 78.0 5.59e-01 97.7% 45.2%
3237928 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 77.0 6.76e-01 97.7% 82.0%
3580961 4095.1.1.3 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.83 78.0 5.66e-01 97.7% 46.9%
5066075 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 78.0 7.43e-01 97.7% 88.7%
3795817 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 78.0 6.57e-01 97.7% 68.7%
4047933 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 78.0 7.34e-01 97.7% 86.0%
3581071 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.83 78.0 5.62e-01 97.7% 42.8%
3633373 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.83 77.0 5.48e-01 97.7% 44.3%
3397951 4095.1.1.2 ↗ alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.83 77.0 5.44e-01 97.7% 39.2%
3962528 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 77.0 7.32e-01 97.7% 85.5%
4995719 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.82 73.0 7.36e-01 97.1% 91.4%
4947392 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.82 77.0 7.13e-01 97.7% 81.0%
4960010 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.82 77.0 7.05e-01 97.7% 79.5%
3927529 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.81 77.0 6.76e-01 99.4% 87.9%
3513779 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 75.0 6.86e-01 97.7% 83.5%
3288874 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 71.0 6.79e-01 97.7% 82.1%
4914243 206.1.3.116 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M, DNA_ligase_A_C 0.79 69.0 6.50e-01 90.8% 79.0%
5007422 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.77 71.0 6.15e-01 97.7% 66.4%
5070559 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.77 70.0 6.13e-01 97.1% 68.3%
5017089 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.76 71.0 6.28e-01 97.7% 70.4%
5003826 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.76 70.0 6.11e-01 97.7% 67.2%
5012458 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.76 69.0 6.13e-01 97.1% 69.2%
3707854 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.74 64.0 5.91e-01 97.1% 73.3%
4668736 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.74 56.0 5.85e-01 97.1% 83.7%
3510295 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.74 64.0 5.76e-01 97.7% 68.9%
3298149 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.74 65.0 5.70e-01 97.1% 65.8%
3492438 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.74 68.0 5.97e-01 97.7% 73.5%
5024218 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.73 69.0 5.51e-01 99.4% 76.2%
3550572 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.73 65.0 5.55e-01 97.1% 61.5%
3397601 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.73 66.0 5.79e-01 97.7% 67.5%
3878834 206.1.3.30 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.73 65.0 5.64e-01 97.1% 64.4%
4027847 206.1.3.4 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.71 67.0 6.06e-01 97.7% 77.3%
3270724 206.1.3.4 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.71 66.0 5.87e-01 97.1% 72.8%
3708389 206.1.3.24 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_lig_T4_1 0.71 67.0 5.22e-01 100.0% 54.9%
193072 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.71 65.0 5.81e-01 97.7% 88.1%
3310146 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.71 67.0 5.07e-01 98.8% 84.4%
3293200 206.1.3.4 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.71 66.0 5.64e-01 98.8% 82.3%
3270508 206.1.3.23 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.70 65.0 5.89e-01 100.0% 80.8%
4983231 206.1.3.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.70 64.0 6.12e-01 97.7% 87.0%
3703188 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.69 63.0 5.65e-01 97.1% 74.0%
3939998 206.1.3.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.62 58.0 5.05e-01 99.4% 74.9%