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ATP-dependent_DNA_ligase

Euk-Vir

Noumeavirus

ATP-dependent_DNA_ligase__YP_009345501__Noumeavirus__1955558

Identity

Accession:
YP_009345501 ↗
Protein ID:
ATP-dependent_DNA_ligase
Kingdom:
euk

Quality

82.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-100
PDB
D2 high residues 330-411
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14743.13 best DNA_ligase_OB_2 47.2 2.50e-12 84.2% 84.9%
D3 medium residues 118-156_279-328
PDB
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4d05A01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.82 66.0 7.11e-01 96.6% 98.7%
1a0iA01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.81 71.0 7.37e-01 97.8% 100.0%
1fviA01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.80 68.0 7.23e-01 94.4% 100.0%
3l2pA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.80 61.0 6.74e-01 89.9% 100.0%
2hivA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.79 72.0 5.28e-01 95.5% 99.5%
6rarI01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.79 66.0 4.94e-01 87.6% 100.0%
6imjA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.78 65.0 4.91e-01 86.5% 100.0%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.78 69.0 5.11e-01 93.3% 100.0%
1vs0A01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.77 62.0 6.66e-01 98.9% 98.7%
1x9nA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.73 60.0 6.18e-01 88.8% 91.7%
3kyhC01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.71 65.0 4.67e-01 100.0% 94.2%
5d1oA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.68 53.0 5.79e-01 88.8% 100.0%
4pz6A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.68 62.0 4.51e-01 100.0% 92.8%
2vugA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.67 51.0 5.61e-01 88.8% 100.0%
2l6oA01 2.40.10.320 Mainly Beta › Beta Barrel › Thrombin, subunit H › Uncharacterised protein PF13642 yp_926445, N-terminal domain 0.55 36.0 3.96e-01 85.4% 83.3%
2z86D02 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.52 32.0 2.33e-01 86.5% 20.4%
6ip0A01 2.60.120.650 Mainly Beta › Sandwich › Jelly Rolls › Cupin 0.51 42.0 2.92e-01 92.1% 64.1%
4w9rB01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.50 37.0 2.67e-01 78.7% 52.4%
4fe9A01 2.60.40.3640 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 41.0 3.72e-01 88.8% 92.5%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4343302 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.80 75.0 4.60e-01 98.9% 51.9%
3237928 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 75.0 5.28e-01 100.0% 94.3%
3633373 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.79 74.0 4.54e-01 98.9% 54.0%
4188682 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 75.0 5.22e-01 100.0% 92.5%
3922871 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 74.0 5.25e-01 97.8% 91.3%
3798407 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.79 73.0 5.35e-01 97.8% 97.7%
3253455 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.79 74.0 4.55e-01 98.9% 52.7%
5036153 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 68.0 5.11e-01 89.9% 100.0%
4600922 4095.1.1.0 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain 0.79 74.0 4.59e-01 98.9% 90.4%
4935888 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 73.0 4.74e-01 97.8% 69.0%
4325132 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.78 74.0 4.84e-01 100.0% 71.8%
4056196 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.78 74.0 4.54e-01 98.9% 90.5%
4947307 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 73.0 4.72e-01 97.8% 69.6%
4263845 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 74.0 5.29e-01 100.0% 96.5%
4012824 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.78 72.0 5.13e-01 97.8% 98.3%
3378267 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.78 73.0 4.51e-01 98.9% 55.0%
4495705 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 74.0 5.27e-01 98.9% 100.0%
5031580 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 72.0 5.32e-01 96.6% 99.5%
4302481 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 73.0 5.28e-01 97.8% 98.6%
2559783 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 71.0 5.25e-01 95.5% 100.0%
4399570 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 71.0 5.14e-01 96.6% 99.6%
5039677 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 74.0 5.33e-01 100.0% 95.5%
4951306 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 73.0 4.56e-01 98.9% 87.7%
3605538 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 73.0 5.05e-01 100.0% 92.5%
5042001 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 72.0 4.75e-01 98.9% 72.0%
3643093 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 73.0 5.21e-01 100.0% 95.7%
5016269 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 72.0 4.64e-01 97.8% 71.6%
3580961 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.77 72.0 4.53e-01 100.0% 58.1%
4977191 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.77 73.0 5.33e-01 100.0% 96.3%
3599023 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.77 72.0 5.15e-01 98.9% 97.4%
4045857 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.77 72.0 4.50e-01 98.9% 88.1%
4982625 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 73.0 5.21e-01 98.9% 92.4%
4289141 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.77 72.0 4.50e-01 98.9% 90.7%
4631711 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.77 71.0 4.51e-01 97.8% 59.7%
4666907 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 71.0 5.26e-01 97.8% 98.5%
4213407 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.77 71.0 4.47e-01 97.8% 87.9%
4966636 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.77 71.0 5.22e-01 97.8% 98.1%
3704759 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 72.0 5.12e-01 100.0% 90.8%
4000577 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 72.0 5.01e-01 100.0% 99.6%
4937749 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 72.0 4.73e-01 100.0% 70.0%
3960632 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.77 72.0 5.35e-01 100.0% 99.0%
4945406 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 72.0 5.31e-01 100.0% 99.5%
3182465 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 72.0 5.02e-01 100.0% 93.3%
3387834 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 68.0 5.21e-01 94.4% 100.0%
4473535 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.76 71.0 4.66e-01 98.9% 71.8%
1245394 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 70.0 5.29e-01 96.6% 99.5%
4237088 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 72.0 5.36e-01 100.0% 98.5%
4098851 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.76 71.0 4.65e-01 98.9% 74.3%
4683228 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.76 72.0 4.55e-01 100.0% 52.7%
2831771 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 71.0 5.46e-01 100.0% 100.0%
3602296 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.76 71.0 5.12e-01 98.9% 100.0%
3927529 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.75 71.0 5.04e-01 100.0% 94.6%
3799247 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.75 70.0 4.86e-01 98.9% 87.3%
3947455 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.75 67.0 4.95e-01 95.5% 99.1%
3581071 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.75 70.0 4.37e-01 100.0% 53.9%
3939304 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.75 70.0 4.33e-01 100.0% 51.0%
4680450 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.74 67.0 4.91e-01 95.5% 99.5%
3795817 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.74 69.0 4.81e-01 100.0% 86.4%
3328725 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.73 69.0 5.15e-01 100.0% 98.5%
3281941 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.72 65.0 4.90e-01 95.5% 99.5%
5076593 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.71 63.0 4.77e-01 93.3% 98.9%
None 0.71 65.0 4.18e-01 100.0% 58.7%
3697249 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.70 65.0 4.58e-01 100.0% 93.2%
3288874 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.68 63.0 4.72e-01 97.8% 93.8%
5066075 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.68 61.0 4.58e-01 94.4% 99.0%
3716788 206.1.3.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.67 60.0 4.31e-01 100.0% 83.8%
3968582 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.66 62.0 4.73e-01 100.0% 99.5%
4047933 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.66 60.0 4.52e-01 97.8% 96.5%
3539447 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.60 42.0 4.18e-01 82.0% 69.5%
D4 medium residues 157-278
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01068.27 best DNA_ligase_A_M 48.2 1.50e-12 95.1% 47.5%