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ATP-dependent_DNA_ligase

Euk-Vir

Vaccinia_virus

ATP-dependent_DNA_ligase__YP_233058__Vaccinia_virus__10245

Identity

Accession:
YP_233058 ↗
Protein ID:
ATP-dependent_DNA_ligase
Kingdom:
euk

Quality

79.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-79
PDB
D2 high residues 108-190
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04675.20 best DNA_ligase_A_N 39.9 7.10e-10 73.5% 36.8%
D3 high residues 410-551
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04679.22 best DNA_ligase_A_C 52.2 9.40e-14 77.5% 97.9%
D4 medium residues 202-235_289-406
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01068.27 best DNA_ligase_A_M 112.3 3.60e-32 73.7% 58.3%
PF01068.27 DNA_ligase_A_M 27.9 2.50e-06 22.4% 15.2%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l2pA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.98 45.0 7.03e-01 92.1% 100.0%
2hivA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.91 85.0 7.50e-01 96.1% 100.0%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.89 81.0 7.19e-01 94.1% 100.0%
1a0iA01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.85 45.0 6.22e-01 95.4% 97.6%
5d1oA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.83 40.0 5.93e-01 91.4% 100.0%
4d05A01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.83 41.0 5.79e-01 95.4% 97.4%
1x9nA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.82 46.0 6.18e-01 95.4% 100.0%
1vs0A01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.82 40.0 5.74e-01 96.1% 96.1%
2vugA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.82 39.0 5.79e-01 91.4% 100.0%
1fviA01 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.82 43.0 5.98e-01 94.7% 100.0%
6rarI01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.78 69.0 6.21e-01 90.8% 100.0%
6imjA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.78 67.0 6.21e-01 90.1% 100.0%
3ty5A01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.76 72.0 5.48e-01 100.0% 79.1%
4pz6A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.73 67.0 5.70e-01 96.7% 91.9%
3kyhC01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.73 67.0 5.65e-01 96.7% 92.1%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.70 63.0 5.92e-01 94.1% 100.0%
4glwA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.68 59.0 5.15e-01 92.1% 98.6%
4ckbA01 3.30.470.140 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › 0.62 55.0 5.25e-01 95.4% 99.4%
2fp4B02 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.56 34.0 4.29e-01 83.6% 100.0%
3wnzA02 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.54 32.0 3.96e-01 83.6% 96.7%
1x60A01 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.52 26.0 3.62e-01 71.7% 100.0%
ECOD (95)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3799247 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.98 94.0 7.51e-01 97.4% 78.5%
3795817 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.98 94.0 7.46e-01 98.0% 77.4%
3581071 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.97 95.0 6.53e-01 100.0% 48.9%
3378267 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.93 88.0 6.04e-01 98.0% 50.9%
3643093 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.92 86.0 7.19e-01 96.1% 94.5%
3697249 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.92 88.0 7.22e-01 99.3% 94.0%
4325132 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.91 86.0 6.41e-01 97.4% 64.8%
4495705 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.91 85.0 7.19e-01 95.4% 98.7%
4263845 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.91 88.0 7.44e-01 100.0% 97.8%
4343302 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.91 88.0 6.03e-01 100.0% 49.4%
3194296 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.91 87.0 6.86e-01 98.7% 92.0%
4600922 4095.1.1.0 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain 0.91 84.0 5.85e-01 96.1% 48.7%
4188682 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.91 87.0 7.08e-01 99.3% 93.3%
3798407 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.91 86.0 7.41e-01 97.4% 98.1%
4012824 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.91 84.0 7.06e-01 96.1% 97.9%
3253455 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 87.0 5.97e-01 100.0% 49.6%
3182465 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 87.0 7.09e-01 100.0% 94.1%
3704759 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 87.0 7.25e-01 100.0% 90.8%
4935888 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 85.0 6.29e-01 97.4% 61.2%
4045857 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 84.0 5.85e-01 96.7% 49.3%
4000577 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 84.0 6.82e-01 96.7% 98.4%
3922871 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 87.0 7.32e-01 100.0% 93.9%
4945406 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 84.0 7.33e-01 96.7% 98.6%
5039677 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 86.0 7.43e-01 100.0% 96.4%
3580961 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.90 86.0 6.02e-01 100.0% 54.0%
3237928 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 86.0 7.08e-01 99.3% 95.9%
4982625 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.89 84.0 7.12e-01 96.7% 90.7%
3633373 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.89 86.0 5.84e-01 100.0% 50.3%
4977191 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.89 86.0 7.46e-01 100.0% 98.6%
4056196 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.89 85.0 5.84e-01 98.7% 47.5%
5036153 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 79.0 7.12e-01 92.1% 100.0%
5083927 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 78.0 6.76e-01 91.4% 99.1%
4947307 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 85.0 6.32e-01 100.0% 62.7%
3397951 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.88 85.0 5.71e-01 99.3% 46.3%
4213407 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.88 80.0 5.66e-01 94.7% 48.9%
5042001 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 83.0 6.27e-01 98.7% 63.4%
4399570 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 80.0 6.88e-01 95.4% 99.1%
4473535 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.88 83.0 6.22e-01 98.7% 63.3%
3602296 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 80.0 6.87e-01 95.4% 97.3%
3927529 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 83.0 6.91e-01 98.7% 94.2%
3513779 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 80.0 6.91e-01 94.7% 94.5%
4289141 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.87 81.0 5.63e-01 96.1% 47.6%
3939304 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.87 83.0 5.74e-01 100.0% 50.8%
4937749 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 82.0 6.14e-01 98.7% 62.4%
4666907 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 81.0 7.14e-01 96.7% 98.5%
4951306 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 81.0 5.64e-01 96.7% 47.5%
3960632 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.86 80.0 7.09e-01 96.1% 97.6%
4966636 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.86 83.0 7.24e-01 100.0% 99.5%
4683228 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.86 79.0 5.68e-01 96.1% 51.9%
5031580 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 79.0 7.08e-01 95.4% 99.0%
4302481 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.86 79.0 6.89e-01 96.1% 98.1%
4098851 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.85 81.0 6.06e-01 100.0% 66.3%
4237088 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 80.0 7.20e-01 98.7% 98.0%
4631711 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.84 80.0 5.73e-01 98.7% 53.0%
4680450 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 76.0 6.67e-01 94.7% 99.1%
5016269 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 80.0 5.95e-01 100.0% 64.3%
4960010 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 77.0 6.71e-01 96.7% 89.8%
3281941 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.82 76.0 6.89e-01 96.1% 100.0%
4947392 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.82 77.0 6.76e-01 97.4% 91.9%
3612949 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.82 75.0 5.87e-01 96.1% 98.3%
5076593 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.81 76.0 6.95e-01 96.7% 100.0%
4914243 206.1.3.116 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M, DNA_ligase_A_C 0.81 63.0 5.56e-01 78.9% 86.3%
5066075 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 76.0 6.91e-01 98.7% 100.0%
3598802 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.80 73.0 5.90e-01 95.4% 95.9%
3962528 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 73.0 6.54e-01 94.7% 94.5%
1245394 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.80 73.0 6.73e-01 96.1% 99.5%
4047933 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 75.0 6.71e-01 98.7% 97.0%
7114 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.79 72.0 6.12e-01 95.4% 99.1%
3599023 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.79 71.0 6.10e-01 95.4% 96.1%
3387834 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 71.0 6.56e-01 94.7% 100.0%
3605538 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 74.0 6.00e-01 100.0% 92.5%
3288874 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.78 74.0 6.67e-01 98.7% 94.4%
2831771 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.77 71.0 6.60e-01 96.7% 99.5%
3947455 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.75 71.0 6.22e-01 99.3% 100.0%
3784943 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.74 71.0 5.10e-01 100.0% 88.1%
5024218 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.74 70.0 5.35e-01 100.0% 85.3%
None 0.74 70.0 5.11e-01 99.3% 90.0%
4323403 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.74 68.0 5.36e-01 97.4% 79.3%
4468528 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.74 69.0 5.38e-01 98.7% 75.7%
1298640 206.1.3.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.74 68.0 5.70e-01 96.7% 91.2%
3310146 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.73 70.0 5.11e-01 100.0% 86.0%
7119 206.1.3.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.73 69.0 5.74e-01 98.7% 89.8%
3328725 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.73 68.0 6.08e-01 97.4% 97.5%
4983231 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.71 67.0 6.03e-01 98.7% 97.5%
3716788 206.1.3.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme 0.71 67.0 5.46e-01 98.7% 83.5%
5017089 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.70 64.0 5.39e-01 96.7% 77.1%
5007422 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.69 65.0 5.39e-01 98.7% 74.0%
3704365 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.69 64.0 5.58e-01 96.7% 88.4%
5070559 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.69 63.0 5.32e-01 96.7% 75.0%
4943522 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.68 64.0 5.55e-01 98.7% 86.4%
5024079 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.68 59.0 5.42e-01 94.1% 71.5%
3595473 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.68 63.0 5.49e-01 98.7% 88.6%
5003826 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.68 64.0 5.29e-01 100.0% 74.8%
5012458 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.67 63.0 5.34e-01 100.0% 77.1%
4668736 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.65 61.0 6.04e-01 99.3% 97.5%
D5 medium residues 236-288
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01068.27 best DNA_ligase_A_M 51.0 2.10e-13 100.0% 26.0%
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l2pA03 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.99 94.0 6.90e-01 100.0% 44.2%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.85 77.0 5.06e-01 100.0% 26.9%
2hivA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.85 77.0 5.02e-01 100.0% 26.7%
1vs0A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.84 72.0 5.61e-01 100.0% 45.5%
3vnnA00 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.83 75.0 5.63e-01 100.0% 46.0%
3wnzA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.74 62.0 4.66e-01 100.0% 52.1%
1auvA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.74 63.0 5.03e-01 96.2% 54.3%
6rarI01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.74 65.0 4.41e-01 100.0% 36.9%
2vugA03 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.72 63.0 5.11e-01 100.0% 63.7%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.72 62.0 4.34e-01 100.0% 36.1%
1s68A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.70 59.0 4.73e-01 100.0% 64.6%
4uopA01 3.30.1120.170 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.65 45.0 3.77e-01 73.6% 43.0%
1xk5A01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.62 55.0 3.72e-01 100.0% 61.8%
7pupA01 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.62 51.0 3.52e-01 98.1% 41.4%
4tm5A01 3.30.470.10 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain 0.60 49.0 3.84e-01 100.0% 65.2%
3pvlA02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.57 39.0 3.39e-01 75.5% 93.8%
6hq7B02 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.57 40.0 2.67e-01 79.2% 27.7%
5xgbA03 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.57 42.0 2.76e-01 81.1% 28.5%
3hoiA00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.53 43.0 3.06e-01 98.1% 57.0%
3qkgA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 34.0 2.57e-01 73.6% 29.3%
6l4lA01 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.51 37.0 3.15e-01 90.6% 100.0%
4exjB01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 35.0 2.99e-01 77.4% 92.1%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3795817 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.99 95.0 5.79e-01 100.0% 20.0%
3799247 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.99 95.0 5.80e-01 100.0% 20.4%
3581071 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.96 91.0 5.18e-01 100.0% 12.5%
4056196 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.91 81.0 4.62e-01 100.0% 11.6%
4325132 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.91 81.0 4.81e-01 100.0% 15.5%
4047933 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 79.0 5.15e-01 100.0% 25.0%
4982625 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 80.0 5.12e-01 100.0% 22.7%
3962528 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 78.0 5.13e-01 100.0% 25.0%
4631711 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.90 78.0 4.58e-01 100.0% 13.0%
4213407 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 79.0 4.61e-01 100.0% 12.6%
4680450 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 78.0 5.04e-01 100.0% 23.3%
4473535 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 79.0 4.74e-01 100.0% 15.5%
4683228 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 78.0 4.57e-01 100.0% 13.0%
3253455 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.90 81.0 4.64e-01 100.0% 11.6%
4237088 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.90 78.0 5.11e-01 100.0% 25.0%
3960632 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.89 77.0 5.05e-01 100.0% 24.4%
5036153 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.89 76.0 5.00e-01 100.0% 25.1%
4914243 206.1.3.116 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M, DNA_ligase_A_C 0.89 81.0 5.30e-01 100.0% 26.3%
3602296 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.89 79.0 5.03e-01 100.0% 22.7%
4935888 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 77.0 4.58e-01 100.0% 14.9%
5031580 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.88 76.0 5.01e-01 100.0% 25.0%
3798407 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.87 80.0 5.17e-01 100.0% 24.7%
4947307 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 76.0 4.56e-01 100.0% 15.2%
3476026 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.87 79.0 4.90e-01 100.0% 22.6%
4966636 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.87 75.0 4.93e-01 100.0% 24.3%
5042001 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 78.0 4.66e-01 100.0% 16.9%
4399570 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.85 77.0 4.92e-01 100.0% 25.3%
4937749 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 76.0 4.55e-01 100.0% 16.7%
3288874 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.84 72.0 4.80e-01 100.0% 25.6%
4977191 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.84 76.0 4.92e-01 100.0% 25.6%
1837660 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.83 75.0 5.63e-01 100.0% 46.0%
3968582 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.81 69.0 4.64e-01 100.0% 26.3%
3281941 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.81 72.0 4.81e-01 100.0% 26.7%
5036959 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.80 71.0 4.78e-01 98.1% 28.9%
4995719 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.75 67.0 4.62e-01 100.0% 38.9%
2559783 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.74 65.0 4.37e-01 100.0% 35.8%
5024218 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.70 61.0 3.78e-01 100.0% 42.2%
3397601 206.1.3.30 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd 0.61 53.0 3.47e-01 100.0% 52.1%
5016620 267.1.1.3 a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.60 43.0 3.02e-01 81.1% 94.6%
3645497 7508.1.1.1 a/b three-layered sandwiches › O-glucosyltransferase rumi N-terminal domain › O-glucosyltransferase rumi N-terminal domain › O-glucosyltransferase rumi N-terminal domain › Glyco_transf_90 0.59 52.0 3.89e-01 100.0% 69.6%
3594757 264.2.1.0 beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.58 41.0 3.50e-01 96.2% 43.2%
3699329 70.3.1.1 beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.51 35.0 2.19e-01 73.6% 56.6%