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ATPase

Euk-Vir

Heliothis_virescens_ascovirus_3g

ATPase__YP_009702125__Heliothis_virescens_ascovirus_3g__1246651

Identity

Accession:: YP_009702125 ↗
Protein ID:: ATPase
Kingdom:: euk

Quality

74.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Ascoviridae› Ascovirus› Heliothis_virescens_ascovirus_3g

TaxID: 1246651

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-117_833-884

PDB

Domain cluster: rep: CAKLQF020000005.1__CAH1078016.1__SAMEA5780031_01194__00042__D2-132_447-461_478-518

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF13476.13 best	AAA_23	54.9	2.70e-14	68.5%	33.8%
PF13555.13	AAA_29	32.8	6.80e-08	33.3%	74.2%

CATH (38)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5da9A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.87	82.0	6.31e-01	100.0%	94.8%
4i99A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.85	81.0	6.33e-01	100.0%	93.2%
1w1wA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.84	81.0	6.68e-01	100.0%	91.2%
3qf7A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.84	80.0	6.47e-01	100.0%	96.3%
6qj2A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.83	80.0	6.03e-01	100.0%	92.1%
3qktD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.83	80.0	6.25e-01	100.0%	94.3%
2o5vA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.80	72.0	6.99e-01	100.0%	86.2%
1e69A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.79	75.0	6.34e-01	100.0%	92.8%
4abyD00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.77	73.0	5.82e-01	100.0%	86.5%
2awnD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.75	57.0	6.15e-01	100.0%	91.0%
8fefH01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.66	62.0	5.03e-01	100.0%	70.7%
6xgzE01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	61.0	5.26e-01	100.0%	82.2%
1g6hA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	61.0	5.25e-01	100.0%	85.4%
3tuiD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	61.0	5.41e-01	100.0%	90.9%
4huqA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	61.0	5.01e-01	100.0%	75.7%
7tchB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.64	61.0	5.30e-01	100.0%	87.2%
1b0uA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.64	60.0	5.16e-01	100.0%	84.5%
3gfoA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.64	61.0	5.21e-01	100.0%	82.9%
1vplA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.63	60.0	5.26e-01	100.0%	84.9%
4p32B00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	59.0	5.24e-01	100.0%	89.1%
4yerA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	58.0	5.28e-01	100.0%	92.7%
1ji0A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	58.0	5.08e-01	100.0%	85.4%
4g1uD00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	58.0	4.95e-01	100.0%	80.9%
2vf7B01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	58.0	4.55e-01	100.0%	84.5%
7kypE01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	58.0	5.24e-01	100.0%	93.5%
7r8bB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.61	57.0	4.74e-01	100.0%	74.8%
7osfB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	56.0	5.13e-01	100.0%	92.5%
7vufD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.59	52.0	4.80e-01	100.0%	75.1%
1yqtA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.58	55.0	4.62e-01	100.0%	70.7%
2nq2D00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	53.0	4.60e-01	100.0%	77.4%
8db3B02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.55	51.0	4.71e-01	100.0%	79.3%
8ouzD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	50.0	4.51e-01	100.0%	84.7%
6qelJ01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	47.0	4.61e-01	98.2%	87.1%
4tl8F00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	49.0	4.55e-01	100.0%	77.9%
4w88B00	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.53	44.0	3.48e-01	88.1%	96.8%
1l8qA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.52	45.0	4.61e-01	98.8%	93.9%
3ksmA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	29.0	3.29e-01	88.7%	72.2%
2awnC01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	48.0	4.41e-01	100.0%	83.2%

ECOD (90)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4583258	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.87	83.0	5.95e-01	100.0%	98.8%
4396994	3755.3.1.305 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook	0.86	83.0	5.07e-01	100.0%	98.3%
5047148	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.86	83.0	6.41e-01	100.0%	97.6%
5079778	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.86	83.0	5.80e-01	100.0%	96.3%
4984958	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.85	82.0	6.21e-01	100.0%	96.0%
4486484	2004.1.1.799 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_27, AAA_29	0.85	82.0	6.35e-01	100.0%	94.8%
4980165	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.85	82.0	5.81e-01	100.0%	96.3%
4936791	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.85	81.0	5.73e-01	100.0%	94.7%
4947567	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.85	82.0	5.69e-01	100.0%	97.2%
5026249	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.85	81.0	6.62e-01	100.0%	94.0%
4165476	2004.1.1.799 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_27, AAA_29	0.85	81.0	5.67e-01	100.0%	96.2%
5081617	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.85	81.0	6.14e-01	100.0%	98.0%
5031839	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.85	81.0	5.83e-01	100.0%	96.9%
4943724	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.85	81.0	6.15e-01	100.0%	99.1%
3915989	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.84	81.0	5.02e-01	100.0%	96.0%
4193109	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.84	81.0	4.87e-01	100.0%	97.3%
4026040	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.84	81.0	5.40e-01	100.0%	97.9%
3869913	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.84	81.0	5.75e-01	100.0%	92.9%
5069317	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.84	81.0	5.78e-01	100.0%	95.8%
5070649	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.84	81.0	5.08e-01	100.0%	98.0%
4320633	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.84	80.0	5.67e-01	100.0%	96.5%
5073876	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.84	80.0	5.61e-01	100.0%	96.4%
3169716	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.84	81.0	4.82e-01	100.0%	96.5%
4260209	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.84	80.0	5.37e-01	99.4%	99.4%
4999185	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.84	80.0	6.44e-01	100.0%	92.5%
5014173	2004.1.1.293 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15	0.81	77.0	5.89e-01	100.0%	90.1%
4381937	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.79	76.0	5.76e-01	100.0%	96.6%
4946598	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.79	75.0	5.90e-01	100.0%	94.0%
4177936	2004.1.1.929 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FliJ	0.73	69.0	5.09e-01	100.0%	95.0%
4182181	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	69.0	5.39e-01	100.0%	93.9%
None	—		0.66	62.0	4.70e-01	100.0%	68.1%
None	—		0.65	62.0	4.60e-01	100.0%	64.6%
None	—		0.65	62.0	4.85e-01	100.0%	66.7%
4405804	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.65	62.0	4.66e-01	100.0%	66.8%
3469120	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.65	62.0	4.32e-01	100.0%	56.9%
3594385	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.65	62.0	4.76e-01	100.0%	65.0%
3285640	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.65	62.0	5.14e-01	100.0%	77.0%
None	—		0.65	62.0	4.51e-01	100.0%	69.9%
None	—		0.65	61.0	4.80e-01	100.0%	67.0%
None	—		0.65	62.0	3.89e-01	100.0%	37.0%
3319119	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.65	61.0	3.75e-01	100.0%	30.2%
None	—		0.65	61.0	4.57e-01	100.0%	65.2%
None	—		0.65	61.0	4.77e-01	100.0%	75.8%
None	—		0.65	61.0	4.79e-01	100.0%	64.2%
3277151	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.65	61.0	4.74e-01	100.0%	63.5%
3935504	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.65	61.0	4.88e-01	100.0%	68.7%
3178422	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	61.0	3.89e-01	100.0%	32.1%
3257559	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	61.0	3.83e-01	100.0%	32.2%
3642780	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	61.0	4.75e-01	100.0%	74.6%
3206294	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	61.0	4.46e-01	100.0%	52.3%
3701109	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	61.0	4.73e-01	100.0%	63.3%
3176885	1075.1.1.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain	0.64	61.0	3.96e-01	100.0%	33.7%
4026625	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	61.0	4.64e-01	100.0%	59.4%
None	—		0.64	61.0	4.53e-01	100.0%	56.3%
5059489	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	60.0	5.36e-01	100.0%	91.7%
3253705	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	61.0	4.64e-01	100.0%	61.1%
4084730	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	60.0	5.35e-01	100.0%	91.7%
3802853	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	60.0	4.95e-01	100.0%	75.8%
None	—		0.64	60.0	3.79e-01	100.0%	28.7%
3679540	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.64	60.0	4.49e-01	100.0%	56.1%
3377210	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.64	60.0	3.74e-01	100.0%	26.8%
3920127	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	4.93e-01	100.0%	70.9%
3796334	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	4.78e-01	100.0%	69.5%
3864510	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	60.0	4.64e-01	100.0%	69.0%
3728680	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	60.0	3.83e-01	100.0%	29.5%
3263378	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	60.0	4.63e-01	100.0%	63.5%
4945914	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	59.0	5.16e-01	100.0%	86.1%
None	—		0.63	58.0	4.74e-01	95.2%	78.6%
None	—		0.63	60.0	4.92e-01	100.0%	73.3%
4944675	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	5.18e-01	100.0%	83.3%
3280832	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	59.0	5.17e-01	100.0%	82.4%
4023041	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	3.81e-01	100.0%	28.6%
3176421	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	3.78e-01	100.0%	28.2%
None	—		0.63	60.0	4.57e-01	100.0%	60.6%
3650926	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	4.68e-01	100.0%	71.1%
4883689	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	58.0	5.24e-01	97.0%	96.8%
3989088	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	59.0	5.46e-01	100.0%	94.8%
3318299	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.63	59.0	4.62e-01	100.0%	72.2%
3494137	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	4.41e-01	100.0%	56.2%
None	—		0.63	59.0	4.59e-01	100.0%	64.7%
3177669	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	60.0	4.50e-01	100.0%	63.0%
5046127	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.63	59.0	5.11e-01	100.0%	81.5%
3840056	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.62	59.0	5.42e-01	100.0%	96.7%
3707738	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.62	58.0	5.00e-01	100.0%	79.2%
5040682	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.61	57.0	5.27e-01	100.0%	92.1%
4264207	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.61	58.0	4.47e-01	100.0%	89.3%
4273426	2004.1.1.5 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran	0.60	57.0	5.05e-01	100.0%	82.6%
4104952	2004.1.1.45 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MutS_V	0.59	54.0	4.63e-01	100.0%	64.8%
4080756	2004.1.1.45 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MutS_V	0.58	53.0	4.12e-01	100.0%	47.8%
4424832	2004.1.1.45 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MutS_V	0.57	52.0	4.54e-01	100.0%	66.9%

D2 medium residues 118-138_749-832

PDB

Domain cluster: rep: hypothetical_protein_MIV094L__YP_654666__Invertebrate_iridescent_virus_3__345201__D688-779

CATH (35)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3qf7A01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.83	62.0	4.33e-01	100.0%	27.6%
1f2uB00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.81	59.0	5.26e-01	79.0%	55.2%
1e69A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.81	48.0	3.47e-01	72.4%	23.6%
1xexB00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.78	58.0	4.93e-01	79.0%	50.3%
4i99A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.77	66.0	4.58e-01	100.0%	30.1%
3qktD01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.76	69.0	4.75e-01	100.0%	31.8%
6qj2A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.73	66.0	4.55e-01	100.0%	32.3%
4mtnA01	3.30.1480.10	Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain	0.69	53.0	5.50e-01	97.1%	88.4%
2hzlB01	3.40.190.170	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7	0.69	52.0	4.03e-01	78.1%	72.5%
3auxA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.69	64.0	4.35e-01	100.0%	38.5%
2o5vA02	1.20.1050.90	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › RecF/RecN/SMC, N-terminal domain	0.69	62.0	5.24e-01	100.0%	92.6%
4p1eA00	3.40.190.170	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7	0.67	50.0	3.56e-01	77.1%	80.1%
2hpgC00	3.40.190.170	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7	0.67	50.0	3.53e-01	78.1%	78.9%
2mx8A01	1.10.274.70	Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain	0.66	49.0	4.81e-01	78.1%	85.8%
1egaA02	3.30.300.20	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain	0.65	46.0	4.63e-01	72.4%	78.3%
1xkpB00	3.30.1460.10	Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, ›	0.62	41.0	3.96e-01	98.1%	58.7%
6ywnA01	3.30.460.10	Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2	0.62	46.0	4.56e-01	77.1%	89.8%
1mkmA03	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.61	44.0	3.77e-01	76.2%	100.0%
3bguA01	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.60	42.0	4.43e-01	99.0%	80.2%
5llyA02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.59	40.0	3.39e-01	71.4%	90.3%
6n59A02	3.30.70.20	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.58	35.0	3.79e-01	98.1%	72.6%
2fb0A00	3.30.70.100	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.57	39.0	4.06e-01	99.0%	78.7%
2k31A00	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.57	39.0	3.45e-01	70.5%	99.3%
2mj7A00	3.30.310.10	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein	0.56	46.0	4.17e-01	100.0%	66.0%
2cy9B00	3.10.129.10	Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase	0.56	41.0	3.80e-01	76.2%	78.8%
5tjjB02	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.56	40.0	3.41e-01	75.2%	98.9%
2opeA00	3.30.540.20	Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 ›	0.55	40.0	3.88e-01	78.1%	68.3%
2x7bA00	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.54	37.0	3.29e-01	71.4%	50.0%
6g20A01	3.30.450.40	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain	0.54	39.0	3.19e-01	76.2%	71.8%
2lezA00	3.30.2450.10	Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › Secreted effector protein pipB2	0.53	33.0	3.18e-01	94.3%	53.3%
4avaA01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.52	37.0	3.32e-01	92.4%	53.5%
1k8kA04	3.90.640.10	Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4	0.51	35.0	3.76e-01	71.4%	96.7%
6rzqA04	3.90.640.10	Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4	0.51	37.0	4.02e-01	75.2%	94.1%
5ymrC00	3.20.70.20	Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain ›	0.51	42.0	2.53e-01	90.5%	25.6%
1oe4A00	3.40.470.10	Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain	0.50	42.0	3.25e-01	92.4%	83.7%

ECOD (99)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4995209	2004.1.1.308 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21	0.84	64.0	5.53e-01	79.0%	57.4%
5029795	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.82	77.0	5.08e-01	100.0%	40.9%
5032343	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.82	68.0	4.68e-01	86.7%	30.0%
5015079	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.81	75.0	4.83e-01	100.0%	46.2%
5042955	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.80	75.0	4.56e-01	100.0%	62.4%
4260209	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.80	75.0	4.61e-01	100.0%	62.9%
4026019	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.80	74.0	4.62e-01	100.0%	54.6%
5031839	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.79	74.0	4.79e-01	100.0%	47.9%
4086930	3922.1.1.276 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SMC_N, AAA_21	0.79	73.0	4.63e-01	100.0%	54.4%
5079566	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.79	73.0	4.60e-01	100.0%	53.5%
5066104	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.79	73.0	4.53e-01	100.0%	59.1%
4995724	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.79	61.0	4.97e-01	100.0%	45.3%
5066039	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.79	73.0	4.61e-01	100.0%	53.3%
3941012	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.78	72.0	4.79e-01	100.0%	42.6%
4992666	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.78	57.0	4.08e-01	76.2%	27.9%
None	—		0.78	71.0	4.90e-01	97.1%	43.8%
5054541	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.78	72.0	4.43e-01	100.0%	58.8%
5040840	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.78	71.0	4.23e-01	100.0%	67.9%
3275757	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.78	71.0	4.38e-01	100.0%	59.9%
3788511	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.78	71.0	4.59e-01	100.0%	51.2%
4568749	2004.1.1.585 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_21, AAA_23	0.77	71.0	4.86e-01	100.0%	40.3%
5035167	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.77	71.0	4.69e-01	100.0%	39.0%
3825615	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.77	71.0	4.10e-01	100.0%	74.3%
3869820	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.77	71.0	4.36e-01	100.0%	60.5%
3997869	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.77	63.0	4.76e-01	85.7%	40.9%
3614118	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.77	71.0	4.41e-01	100.0%	57.6%
3385272	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.77	70.0	4.04e-01	100.0%	76.0%
4262159	2004.1.1.308 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21	0.76	70.0	4.74e-01	98.1%	45.8%
3415405	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	70.0	4.54e-01	100.0%	36.0%
4073493	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.76	69.0	4.37e-01	100.0%	54.1%
3620317	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	70.0	4.52e-01	100.0%	44.1%
4948353	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	63.0	4.68e-01	100.0%	36.2%
5030588	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	69.0	4.40e-01	100.0%	55.4%
4969095	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.76	69.0	4.55e-01	100.0%	43.6%
4978786	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.76	70.0	4.24e-01	100.0%	62.5%
4146573	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.75	69.0	4.39e-01	100.0%	52.9%
3893988	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.75	69.0	4.32e-01	100.0%	50.1%
3494821	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	69.0	4.34e-01	100.0%	45.4%
5077499	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	69.0	4.59e-01	100.0%	37.7%
3168946	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	69.0	4.76e-01	100.0%	33.2%
3569132	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	69.0	4.23e-01	100.0%	55.2%
3615184	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	69.0	4.30e-01	100.0%	52.2%
3965698	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	68.0	4.17e-01	100.0%	62.9%
3168460	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.75	68.0	4.05e-01	100.0%	69.2%
4179150	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.75	68.0	4.28e-01	100.0%	55.7%
5014331	2004.1.1.293 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15	0.75	67.0	3.98e-01	97.1%	74.6%
4336245	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.75	68.0	4.14e-01	100.0%	63.4%
3715876	2004.1.1.481 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29	0.75	68.0	4.52e-01	100.0%	39.8%
4480602	2004.1.1.199 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B	0.74	68.0	4.34e-01	100.0%	55.1%
3974536	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.74	68.0	4.46e-01	100.0%	45.4%
5026579	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.74	67.0	4.59e-01	100.0%	30.0%
4070494	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.74	67.0	4.47e-01	100.0%	41.9%
5032566	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.74	68.0	4.41e-01	100.0%	50.8%
3938802	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.74	67.0	4.40e-01	100.0%	38.9%
5045400	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.74	67.0	4.45e-01	97.1%	45.2%
4448955	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.74	67.0	4.43e-01	100.0%	46.5%
4546376	3922.1.1.276 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SMC_N, AAA_21	0.74	67.0	4.32e-01	100.0%	53.2%
4034416	2004.1.1.481 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29	0.74	67.0	4.49e-01	100.0%	40.8%
4968654	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.74	65.0	4.61e-01	100.0%	32.4%
4559671	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.74	67.0	3.94e-01	100.0%	70.4%
5028909	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.73	68.0	4.32e-01	100.0%	53.3%
3731612	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.73	67.0	3.99e-01	100.0%	66.9%
4191276	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	67.0	4.01e-01	100.0%	69.5%
3696935	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.73	67.0	4.18e-01	100.0%	55.7%
5063778	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.73	66.0	4.33e-01	100.0%	51.3%
4345017	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.73	67.0	4.08e-01	100.0%	62.4%
4230460	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.73	66.0	3.98e-01	100.0%	67.9%
4021462	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	67.0	4.16e-01	100.0%	54.0%
3640612	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.73	68.0	3.96e-01	100.0%	72.5%
3831229	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.73	67.0	4.14e-01	100.0%	57.2%
3601755	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.73	67.0	4.20e-01	100.0%	50.6%
3416429	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.73	66.0	4.42e-01	100.0%	46.5%
4932757	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.73	59.0	4.92e-01	86.7%	52.0%
4310983	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.73	66.0	4.08e-01	100.0%	60.4%
3246493	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.73	66.0	4.25e-01	100.0%	31.5%
4305317	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.72	63.0	3.79e-01	94.3%	73.1%
3911275	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.72	65.0	4.36e-01	100.0%	45.6%
3921243	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.72	67.0	4.02e-01	100.0%	66.8%
4512246	2004.1.1.615 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23, AAA_29	0.72	65.0	4.07e-01	100.0%	59.9%
3849007	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.72	65.0	4.05e-01	100.0%	60.5%
3953503	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.72	65.0	4.34e-01	100.0%	41.2%
4984240	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.72	65.0	4.06e-01	100.0%	67.3%
4030051	2004.1.1.480 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29	0.72	65.0	4.37e-01	100.0%	39.2%
4279265	2004.1.1.481 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29	0.72	64.0	4.35e-01	100.0%	43.8%
4133370	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.72	64.0	4.08e-01	100.0%	55.8%
3937752	2004.1.1.615 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23, AAA_29	0.71	64.0	4.07e-01	100.0%	58.5%
3401140	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.71	65.0	4.24e-01	100.0%	52.0%
4407693	2004.1.1.525 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23, AAA_27, SbcC_Walker_B	0.71	65.0	4.52e-01	100.0%	31.6%
5062806	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.71	63.0	4.36e-01	100.0%	30.1%
4483079	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.71	64.0	4.33e-01	100.0%	40.5%
5072279	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.71	64.0	4.31e-01	99.0%	41.3%
3278767	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.71	64.0	3.88e-01	100.0%	67.3%
4674184	2004.1.1.798 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15, AAA_29	0.70	63.0	4.28e-01	100.0%	41.3%
3590398	2004.1.1.433 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23	0.70	63.0	3.89e-01	100.0%	63.0%
4118534	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.70	64.0	4.06e-01	100.0%	54.3%
4177936	2004.1.1.929 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FliJ	0.70	64.0	4.23e-01	100.0%	50.0%
3843214	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.69	62.0	3.89e-01	98.1%	63.0%
4927601	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.63	54.0	3.62e-01	95.2%	42.8%
4674581	3281.1.1.4 ↗	alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M,Proton_antipo_N,NADH5_C	0.57	44.0	2.71e-01	82.9%	73.4%

D3 medium residues 139-169_707-748

PDB

Domain cluster: representative

CATH (84)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3onjA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.95	65.0	5.83e-01	100.0%	53.6%
3a8pA02	6.10.140.680	Special › Helix non-globular › Helix Hairpins ›	0.93	81.0	6.76e-01	90.4%	64.9%
2rkhA02	1.20.1280.20	Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain	0.93	63.0	6.23e-01	97.3%	67.1%
4wpeA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.93	81.0	5.23e-01	100.0%	24.4%
4iloA00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.92	87.0	5.85e-01	100.0%	34.7%
3icxA01	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.92	81.0	8.04e-01	93.2%	97.3%
1zpyA00	6.10.140.1960	Special › Helix non-globular › Helix Hairpins ›	0.92	72.0	6.61e-01	90.4%	65.9%
4l0rB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.92	80.0	8.04e-01	100.0%	91.8%
4a17U01	1.10.287.310	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.92	74.0	7.32e-01	98.6%	80.5%
2rd0B00	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.91	86.0	6.75e-01	100.0%	55.4%
6gy8A01	1.20.1170.10	Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; ›	0.91	86.0	5.36e-01	100.0%	33.1%
2gd5A00	6.10.140.1230	Special › Helix non-globular › Helix Hairpins ›	0.90	81.0	6.30e-01	100.0%	49.3%
1yg2A02	6.10.140.190	Special › Helix non-globular › Helix Hairpins ›	0.89	80.0	7.33e-01	94.5%	78.9%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.89	77.0	7.81e-01	91.8%	100.0%
2ch7A00	1.10.287.950	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein	0.89	82.0	5.24e-01	100.0%	70.9%
3sjqC00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.89	80.0	7.69e-01	94.5%	86.3%
3rq9A00	1.10.287.2500	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.88	70.0	6.90e-01	93.2%	78.2%
3nvoB02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.88	79.0	6.65e-01	100.0%	60.3%
1kfdA02	1.20.1060.10	Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4	0.88	72.0	7.39e-01	98.6%	88.7%
2cazD00	6.10.140.820	Special › Helix non-globular › Helix Hairpins ›	0.87	69.0	7.53e-01	95.9%	100.0%
2ke4A00	6.10.140.470	Special › Helix non-globular › Helix Hairpins ›	0.87	80.0	7.20e-01	100.0%	85.7%
3r84A00	1.10.287.3490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.87	81.0	7.83e-01	100.0%	96.3%
4nb5B02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.87	72.0	7.63e-01	93.2%	100.0%
1wleA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.87	82.0	6.88e-01	100.0%	67.5%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.87	80.0	5.58e-01	100.0%	40.0%
2bdeA03	1.20.58.1160	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.86	70.0	6.85e-01	100.0%	80.5%
1ucuA01	6.10.280.190	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.86	69.0	7.13e-01	100.0%	91.2%
8d7hD01	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.86	68.0	5.02e-01	90.4%	35.3%
3hr0B01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.85	77.0	7.47e-01	98.6%	89.9%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.85	78.0	5.37e-01	100.0%	52.4%
2etnB01	1.10.287.180	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain	0.84	73.0	7.22e-01	98.6%	89.5%
3fd9A03	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.84	76.0	7.66e-01	97.3%	100.0%
2iakA01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	76.0	5.49e-01	100.0%	38.0%
4b6xA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	73.0	7.53e-01	100.0%	100.0%
2gtsA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.83	72.0	7.10e-01	94.5%	89.6%
1z0pA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.83	68.0	6.82e-01	87.7%	87.7%
7wivA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.82	76.0	4.84e-01	100.0%	23.5%
1rv2D04	1.10.287.690	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain	0.82	70.0	7.17e-01	97.3%	95.7%
1sg2A00	3.30.910.20	Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain	0.82	72.0	5.69e-01	100.0%	48.9%
1a36A04	1.10.132.10	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 ›	0.82	73.0	5.43e-01	97.3%	42.3%
4dylA02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.82	75.0	6.86e-01	100.0%	92.6%
1pd3A00	1.10.287.230	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.82	58.0	6.59e-01	78.1%	100.0%
3ehfD01	1.20.5.1930	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.81	65.0	7.03e-01	87.7%	98.4%
1avoB00	1.20.120.180	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain	0.81	73.0	5.75e-01	95.9%	56.4%
2fb5A01	1.10.287.770	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like	0.81	66.0	6.66e-01	86.3%	100.0%
1fxkB00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.81	71.0	6.27e-01	100.0%	87.2%
4e4eA01	1.10.287.990	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain	0.80	64.0	6.55e-01	100.0%	88.7%
1nt2B02	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.80	63.0	6.58e-01	86.3%	100.0%
3r84B00	6.10.280.160	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22	0.79	73.0	7.05e-01	100.0%	91.3%
1b3qA01	1.10.287.560	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain	0.79	58.0	6.21e-01	79.5%	91.9%
1uurA01	1.20.58.240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1	0.79	68.0	5.94e-01	95.9%	67.3%
2fcwA00	1.20.81.10	Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain	0.79	70.0	6.19e-01	100.0%	73.6%
1vx7301	1.10.287.310	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.78	64.0	6.45e-01	87.7%	89.2%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.78	71.0	6.30e-01	100.0%	85.3%
6tkvA01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.78	65.0	6.77e-01	93.2%	97.1%
1wa8A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.78	66.0	5.98e-01	94.5%	70.7%
3b2eF00	1.10.287.660	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.78	60.0	6.39e-01	97.3%	98.4%
1t72A02	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.77	66.0	6.00e-01	97.3%	71.4%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.77	67.0	5.24e-01	100.0%	86.2%
3sfvB02	6.10.140.2010	Special › Helix non-globular › Helix Hairpins ›	0.77	70.0	4.94e-01	97.3%	37.0%
6r1nA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.76	68.0	6.04e-01	100.0%	70.9%
1hciA03	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.75	65.0	5.52e-01	100.0%	59.2%
1fxkC00	1.10.287.370	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.75	65.0	5.40e-01	100.0%	97.7%
4cqiA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.74	65.0	5.80e-01	100.0%	72.9%
1vcsA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.74	61.0	5.45e-01	91.8%	64.7%
3okqA00	1.20.58.1540	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain	0.73	64.0	5.38e-01	100.0%	73.6%
3g80A00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.70	57.0	5.77e-01	98.6%	91.8%
3favD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.70	61.0	6.01e-01	98.6%	93.6%
2qffA00	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.69	47.0	4.69e-01	83.6%	68.9%
1ku9A02	1.10.287.450	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin	0.69	54.0	5.64e-01	89.0%	100.0%
6h9xA01	1.10.287.40	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain	0.69	59.0	5.35e-01	100.0%	70.6%
2xokP00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.68	56.0	5.63e-01	90.4%	91.9%
5dn6J00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.67	56.0	5.67e-01	91.8%	90.5%
4errB00	1.20.58.1190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.66	55.0	5.35e-01	100.0%	83.1%
6ynwH01	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.66	51.0	5.10e-01	100.0%	81.1%
2x6hA03	1.10.1070.11	Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain	0.66	46.0	3.30e-01	71.2%	75.0%
4q20A01	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.65	52.0	5.11e-01	91.8%	82.9%
1dd5A01	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.65	57.0	4.96e-01	95.9%	80.7%
2gv9A05	1.10.287.690	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain	0.65	45.0	4.80e-01	78.1%	91.5%
4v1gA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.65	57.0	5.49e-01	100.0%	88.2%
2b3tB01	6.10.140.1980	Special › Helix non-globular › Helix Hairpins ›	0.63	45.0	4.72e-01	93.2%	86.2%
2wgmA01	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.62	51.0	4.95e-01	91.8%	84.1%
2kg7B00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.60	50.0	4.65e-01	100.0%	72.2%
3ktdD02	1.10.3660.10	Mainly Alpha › Orthogonal Bundle › 6-phosphogluconate dehydrogenase C-terminal fold › 6-phosphogluconate dehydrogenase C-terminal like domain	0.57	44.0	3.91e-01	84.9%	56.9%

ECOD (79)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3953503	2004.1.1.442 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21	0.95	91.0	5.46e-01	100.0%	18.3%
4262159	2004.1.1.308 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21	0.95	82.0	5.07e-01	100.0%	19.1%
3218879	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.95	65.0	7.21e-01	100.0%	86.7%
4405928	5086.1.1.196 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YknX	0.94	80.0	8.25e-01	98.6%	92.9%
3930829	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.94	83.0	8.23e-01	100.0%	89.3%
4483079	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.93	89.0	5.37e-01	100.0%	21.0%
4967728	5058.1.1.100 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PsiE	0.92	77.0	5.93e-01	87.7%	49.0%
3535521	1073.1.1.11 ↗	alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › WWC1	0.92	77.0	7.67e-01	87.7%	85.3%
3596479	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.91	85.0	6.75e-01	100.0%	54.6%
5002671	3755.3.1.637 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121	0.91	79.0	5.93e-01	100.0%	41.9%
3935462	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.91	85.0	6.28e-01	100.0%	48.2%
5035167	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.90	84.0	5.11e-01	100.0%	19.5%
3595103	3860.1.1.0 ↗	alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm	0.90	84.0	6.69e-01	100.0%	54.8%
3780286	244.1.1.6 ↗	a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase	0.90	84.0	4.86e-01	100.0%	13.6%
4984327	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.90	80.0	6.95e-01	94.5%	72.4%
3770253	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.90	84.0	6.06e-01	100.0%	80.0%
3741801	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.89	85.0	6.86e-01	100.0%	59.2%
4366813	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.89	82.0	6.99e-01	100.0%	64.5%
3317382	605.4.1.5 ↗	alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › SCAB-ABD, SCAB_CC	0.89	83.0	5.94e-01	100.0%	42.1%
3681387	632.22.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats	0.89	76.0	6.28e-01	100.0%	55.0%
3298709	605.1.1.141 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N	0.89	76.0	6.18e-01	100.0%	52.8%
5057549	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.89	79.0	6.51e-01	95.9%	57.6%
4652719	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.89	83.0	7.52e-01	100.0%	77.9%
3607135	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.88	81.0	6.50e-01	100.0%	95.6%
3898383	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.88	80.0	6.60e-01	98.6%	69.6%
4177363	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.88	83.0	6.41e-01	100.0%	51.0%
4266268	192.8.1.376 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › RRP36	0.88	76.0	5.84e-01	100.0%	44.7%
4954894	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.88	76.0	6.07e-01	90.4%	50.8%
3295251	605.1.1.185 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF7615	0.88	76.0	6.50e-01	100.0%	60.9%
4336724	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.87	77.0	6.63e-01	94.5%	69.1%
3349325	5086.1.1.135 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF7615	0.87	75.0	7.28e-01	100.0%	83.7%
3988263	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.87	81.0	5.95e-01	100.0%	46.3%
3599773	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.87	74.0	5.35e-01	100.0%	35.3%
4034092	150.5.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like	0.86	78.0	7.80e-01	97.3%	96.0%
3535762	3187.1.1.2 ↗	alpha bundles › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › DUF4795	0.86	80.0	5.70e-01	100.0%	37.4%
3598199	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.86	79.0	5.75e-01	100.0%	78.4%
3916825	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.85	78.0	6.05e-01	100.0%	91.3%
4474737	3711.1.1.44 ↗	alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Med11	0.85	79.0	7.27e-01	100.0%	93.3%
3513888	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.85	75.0	5.72e-01	100.0%	44.5%
3488333	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.85	78.0	6.58e-01	98.6%	67.8%
3864552	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.84	75.0	6.73e-01	97.3%	75.0%
3663959	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.84	78.0	6.33e-01	100.0%	56.9%
3839497	150.5.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like	0.84	77.0	7.30e-01	100.0%	85.9%
3574255	5086.1.1.87 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING	0.84	77.0	6.14e-01	100.0%	53.3%
3989466	1075.1.2.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX	0.84	76.0	4.39e-01	100.0%	11.8%
5012794	4333.1.1.0 ↗	a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain	0.83	73.0	4.58e-01	95.9%	22.0%
4028874	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.81	73.0	4.77e-01	100.0%	40.3%
3275930	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.80	71.0	4.87e-01	100.0%	36.8%
3731974	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.80	73.0	6.25e-01	98.6%	70.0%
3700672	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.80	72.0	6.16e-01	100.0%	68.7%
3599032	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.79	70.0	4.91e-01	100.0%	32.2%
3512620	3755.4.1.1 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2	0.79	69.0	5.41e-01	100.0%	63.1%
4586684	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.78	68.0	5.59e-01	100.0%	53.8%
3962893	150.5.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like	0.78	70.0	6.42e-01	100.0%	87.4%
5057329	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.78	70.0	5.57e-01	100.0%	65.5%
4966215	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.78	70.0	5.32e-01	100.0%	44.2%
3535653	633.16.1.4 ↗	alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like › SOAR	0.78	69.0	5.88e-01	100.0%	74.2%
4954892	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.77	69.0	4.37e-01	100.0%	20.8%
3745112	3755.3.1.298 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING	0.77	68.0	5.80e-01	100.0%	66.7%
3450594	3826.1.1.0 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR)	0.77	68.0	6.11e-01	97.3%	72.0%
3187995	603.1.1.3 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE	0.77	69.0	6.04e-01	100.0%	66.4%
3275757	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.76	67.0	3.94e-01	100.0%	43.3%
3917938	4177.1.1.5 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5	0.76	66.0	4.76e-01	100.0%	36.3%
4473674	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.75	65.0	5.76e-01	98.6%	65.5%
3621305	150.1.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin	0.75	66.0	5.25e-01	100.0%	49.3%
3608554	3291.1.1.1 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7	0.75	66.0	5.29e-01	100.0%	51.0%
4352409	375.1.1.300 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SOAR	0.74	65.0	5.32e-01	100.0%	55.0%
3170876	192.7.1.30 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › CUX1_N	0.74	65.0	5.65e-01	100.0%	66.1%
3330505	603.1.1.3 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE	0.74	64.0	5.77e-01	100.0%	70.0%
3168929	4323.1.1.1 ↗	alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I	0.74	65.0	4.93e-01	100.0%	42.3%
3286299	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.74	64.0	5.62e-01	100.0%	65.5%
3396404	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.74	65.0	5.46e-01	100.0%	64.0%
4039014	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.74	64.0	5.62e-01	100.0%	65.5%
3791628	1203.1.2.0 ↗	alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2	0.73	65.0	5.21e-01	100.0%	51.0%
3703453	601.19.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein	0.73	64.0	4.55e-01	100.0%	33.8%
5062668	3755.1.1.0 ↗	alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related	0.73	63.0	5.38e-01	100.0%	59.2%
4671	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.73	63.0	5.60e-01	100.0%	66.4%
3368750	192.8.1.263 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF7615	0.72	61.0	5.42e-01	95.9%	66.7%
2600	101.1.2.14 ↗	alpha arrays › HTH › HTH › winged helix domain › HTH_5	0.69	54.0	4.33e-01	89.0%	42.4%

D4 medium residues 185-253

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5h9cA00	1.10.287.210	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.83	58.0	5.53e-01	72.5%	64.1%

D5 medium residues 254-278_585-695

PDB

Domain cluster: representative

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6xj1A01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.85	69.0	5.53e-01	83.8%	55.9%
7sgrA02	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.85	49.0	3.64e-01	81.6%	25.2%
2v0oB00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.84	70.0	5.46e-01	87.5%	51.7%
6bl6B01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.83	46.0	3.41e-01	82.4%	23.7%
4wpeA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.83	69.0	5.31e-01	86.8%	54.5%
4flaC00	6.10.250.2560	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.82	58.0	6.06e-01	72.8%	99.2%
5y06A01	1.10.287.1490	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	60.0	4.90e-01	76.5%	46.3%
3k29A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.80	64.0	6.04e-01	83.8%	77.6%
3vkgA12	1.10.287.2610	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.79	56.0	4.75e-01	72.8%	81.9%
6iknD01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.78	64.0	4.95e-01	86.8%	43.1%
1fewA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.73	51.0	4.68e-01	72.1%	75.1%
1uruA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	57.0	4.85e-01	85.3%	53.1%
1i4dA00	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.72	50.0	4.45e-01	70.6%	52.1%
3syvA01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.70	57.0	4.68e-01	91.2%	48.6%
4nswB01	1.20.1270.60	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain	0.67	61.0	4.90e-01	97.8%	52.7%
3sfvB02	6.10.140.2010	Special › Helix non-globular › Helix Hairpins ›	0.61	36.0	3.15e-01	77.2%	40.0%

ECOD (49)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4939828	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.95	68.0	4.87e-01	73.5%	75.5%
4086306	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.91	73.0	5.94e-01	82.4%	77.3%
3970019	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.90	70.0	5.68e-01	79.4%	73.5%
3831567	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.88	68.0	6.18e-01	78.7%	74.7%
3470680	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.87	65.0	4.41e-01	76.5%	90.6%
3788539	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.86	65.0	4.44e-01	76.5%	83.0%
3592972	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.86	65.0	5.68e-01	77.9%	64.6%
3634628	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.84	66.0	4.55e-01	80.9%	77.3%
3712411	3939.1.1.0 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain	0.84	61.0	4.85e-01	74.3%	87.6%
3919840	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.84	63.0	5.21e-01	76.5%	57.3%
3498560	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.84	60.0	4.71e-01	73.5%	46.0%
5052608	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.83	62.0	5.48e-01	76.5%	82.2%
4020772	4207.1.1.64 ↗	alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › PF30554	0.83	60.0	5.19e-01	75.0%	94.1%
3169716	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.83	72.0	4.19e-01	91.2%	50.8%
4001186	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.83	63.0	5.50e-01	77.9%	73.7%
3865253	209.1.1.1 ↗	a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C	0.82	66.0	4.89e-01	83.8%	41.8%
4028874	4177.1.1.1 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH	0.82	66.0	4.93e-01	83.8%	48.2%
5066104	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.81	62.0	4.02e-01	78.7%	57.8%
3699468	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.81	64.0	5.52e-01	81.6%	67.0%
5047075	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.80	69.0	4.99e-01	89.0%	76.5%
4392204	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.80	62.0	5.20e-01	80.9%	76.4%
4968656	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.80	59.0	4.23e-01	75.7%	92.0%
3482286	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.80	57.0	4.94e-01	73.5%	84.5%
3908132	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.80	66.0	5.26e-01	86.8%	54.7%
5010596	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.79	61.0	5.07e-01	78.7%	85.5%
3867942	3755.3.1.303 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th	0.79	58.0	4.76e-01	75.7%	76.2%
4992667	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.79	58.0	4.52e-01	75.7%	49.8%
4516566	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.78	62.0	5.48e-01	82.4%	83.7%
3712647	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.77	70.0	5.23e-01	97.1%	59.1%
3731612	2004.1.1.567 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23	0.77	60.0	3.62e-01	79.4%	55.5%
3965792	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.77	70.0	5.53e-01	99.3%	62.5%
4956931	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.77	58.0	3.85e-01	78.7%	33.7%
4471073	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.76	58.0	4.16e-01	78.7%	36.2%
4520297	3939.1.1.0 ↗	alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain	0.75	67.0	5.39e-01	93.4%	66.1%
3691415	2004.1.1.748 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_23, SbcC_Walker_B	0.73	63.0	4.18e-01	93.4%	51.1%
3168460	2004.1.1.429 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15	0.72	64.0	3.91e-01	94.1%	65.6%
3611166	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.72	55.0	4.75e-01	78.7%	79.5%
5040840	2004.1.1.87 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N	0.71	60.0	3.79e-01	91.2%	31.1%
5056871	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.70	56.0	4.24e-01	83.8%	86.1%
3843224	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.70	55.0	4.51e-01	81.6%	53.3%
4346691	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.66	43.0	3.51e-01	94.9%	35.9%
4260979	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.66	57.0	4.54e-01	92.6%	81.1%
3623410	2004.1.1.198 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23	0.66	50.0	3.29e-01	78.7%	44.7%
3741747	632.22.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats	0.65	52.0	4.05e-01	83.1%	73.7%
4941676	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	47.0	4.28e-01	75.7%	80.6%
4337633	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.61	47.0	3.57e-01	78.7%	87.7%
3241140	2004.1.1.199 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B	0.60	54.0	3.42e-01	97.1%	59.0%
4219808	192.1.1.0 ↗	alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain	0.58	53.0	3.87e-01	98.5%	78.6%
3687766	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.57	43.0	3.68e-01	92.6%	48.4%

D6 medium residues 279-348_565-584

PDB

Domain cluster: representative

CATH (25)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3fxdB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.78	38.0	4.64e-01	98.9%	72.4%
1dkxA02	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.78	43.0	4.58e-01	98.9%	61.3%
1vpdA02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.77	42.0	3.65e-01	100.0%	37.4%
2nn4A00	1.10.287.760	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like	0.77	32.0	3.85e-01	88.9%	56.5%
2qywA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.76	46.0	4.52e-01	100.0%	56.8%
2p5tA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.73	45.0	4.52e-01	100.0%	60.9%
4abmD00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.72	48.0	5.24e-01	98.9%	80.5%
2oexA01	1.20.120.560	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain	0.72	49.0	4.12e-01	100.0%	44.1%
1zkeA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.72	46.0	4.81e-01	97.8%	71.6%
4bwcA02	1.10.439.20	Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2	0.71	36.0	3.26e-01	97.8%	37.6%
3w6zA02	1.10.1040.10	Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2	0.71	41.0	3.66e-01	100.0%	43.0%
1t72A01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.70	44.0	4.00e-01	100.0%	48.7%
4kb2A01	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.69	45.0	4.21e-01	100.0%	55.0%
3nbxX03	1.20.58.1510	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.69	38.0	3.64e-01	98.9%	48.5%
3swhA01	1.10.357.50	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 ›	0.69	40.0	3.27e-01	100.0%	31.5%
1s35A02	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	42.0	3.90e-01	100.0%	55.5%
2odmA00	1.10.287.750	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like	0.62	32.0	3.38e-01	96.7%	55.7%
4ioeA00	1.10.287.850	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain	0.60	42.0	4.27e-01	96.7%	74.7%
4wr4A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.58	33.0	3.21e-01	97.8%	47.6%
6g94A00	1.20.950.20	Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C	0.57	43.0	3.53e-01	100.0%	42.4%
1mabG00	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.56	48.0	4.31e-01	100.0%	66.9%
1qb2A00	1.10.260.30	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › Signal recognition particle, SRP54 subunit, M-domain	0.55	41.0	3.97e-01	81.1%	95.3%
7zxkC01	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.53	45.0	3.84e-01	95.6%	92.7%
3axjB01	1.20.58.190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1	0.52	45.0	3.67e-01	100.0%	53.5%
5jajA03	1.20.1320.30	Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 ›	0.51	38.0	3.54e-01	81.1%	62.1%

ECOD (28)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3238851	3812.1.1.0 ↗	alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE	0.78	48.0	4.57e-01	98.9%	54.3%
4250162	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.74	50.0	4.32e-01	100.0%	46.7%
5052222	3812.1.1.0 ↗	alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE	0.74	46.0	4.79e-01	100.0%	67.1%
4022519	622.1.1.0 ↗	alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain	0.72	37.0	3.86e-01	96.7%	54.1%
3529859	4177.1.1.10 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH	0.70	52.0	3.47e-01	100.0%	23.4%
4095048	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.68	46.0	4.18e-01	100.0%	52.5%
3697356	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.68	36.0	3.73e-01	100.0%	55.3%
3211724	632.1.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain	0.67	37.0	3.67e-01	98.9%	51.6%
3404343	192.29.1.1 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom	0.66	43.0	4.37e-01	100.0%	66.7%
3441499	109.4.1.359 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C	0.65	48.0	3.09e-01	77.8%	54.2%
4997392	3930.1.1.3 ↗	alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical	0.65	52.0	4.48e-01	96.7%	55.0%
3487245	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.65	43.0	3.99e-01	98.9%	53.9%
5012967	601.7.1.34 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129	0.64	37.0	3.59e-01	88.9%	49.5%
3718312	604.1.1.118 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N	0.64	45.0	3.84e-01	100.0%	46.2%
3843998	174.1.1.25 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Mtp	0.62	42.0	3.56e-01	70.0%	97.2%
3910525	109.4.1.87 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec6	0.61	48.0	2.88e-01	83.3%	33.9%
3861313	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.60	49.0	4.44e-01	100.0%	66.1%
5001522	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.60	40.0	3.86e-01	100.0%	60.2%
3394753	192.5.1.12 ↗	alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PH_19	0.60	39.0	4.26e-01	98.9%	84.3%
4542879	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.59	43.0	3.71e-01	76.7%	89.0%
4952627	142.1.1.14 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › NiFe_hyd_3_EhaA	0.59	34.0	3.52e-01	88.9%	60.0%
3712359	150.3.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine	0.58	53.0	4.26e-01	100.0%	56.5%
3785344	5086.1.1.0 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins	0.58	42.0	3.74e-01	100.0%	55.8%
3397986	3755.4.1.1 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2	0.57	50.0	3.87e-01	100.0%	46.1%
3502658	603.1.1.100 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017	0.57	51.0	4.23e-01	100.0%	58.6%
3423908	6155.1.1.0 ↗	alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter	0.57	37.0	3.68e-01	95.6%	63.2%
3582569	3755.3.1.348 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › zf-C4H2	0.54	49.0	3.54e-01	100.0%	36.7%
3280601	150.5.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like	0.53	42.0	3.88e-01	98.9%	66.1%

D7 medium residues 349-406_543-564

PDB

Domain cluster: representative

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1gvnA00	1.10.8.130	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.70	38.0	3.74e-01	100.0%	48.3%
4dlqA02	1.25.40.610	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.61	41.0	3.95e-01	70.0%	76.8%
1u7lA02	1.20.1460.10	Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2	0.56	52.0	3.91e-01	100.0%	88.5%
1s35A01	1.20.58.60	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.52	35.0	3.36e-01	72.5%	95.0%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4240705	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.78	42.0	4.10e-01	100.0%	49.4%
3918310	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.69	51.0	4.61e-01	77.5%	97.1%
5044061	3883.1.1.1 ↗	alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf	0.65	47.0	3.60e-01	76.2%	43.9%
3472404	101.1.15.2 ↗	alpha arrays › HTH › HTH › HAT1, C-terminal domain › HAT1_C	0.61	42.0	3.51e-01	72.5%	70.3%
3857549	3352.1.1.21 ↗	alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DIE2_ALG10	0.58	40.0	2.53e-01	72.5%	26.3%
3792833	109.21.1.4 ↗	alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Sec16_C,Sec16	0.55	38.0	2.36e-01	72.5%	13.5%
3632538	3978.1.1.2 ↗	alpha complex topology › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › Integral membrane Acyl-CoA desaturase › FA_hydroxylase	0.52	37.0	2.75e-01	75.0%	72.6%

D8 medium residues 407-542

PDB