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Alpha-amanitin_target_protein
Euk-VirEptesipox_virus
Alpha-amanitin_target_protein__YP_009408121__Eptesipox_virus__1329402
Identity
- Accession:
- YP_009408121 ↗
- Protein ID:
- Alpha-amanitin_target_protein
- Kingdom:
- euk
Quality
81.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Vespertilionpoxvirus›
Eptesipox_virus
TaxID: 1329402
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-87
Domain cluster:
representative
CATH (34)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6h7bA01 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.71 | 43.0 | 4.63e-01 | 80.5% | 70.3% |
| 5t3wA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 52.0 | 4.50e-01 | 86.2% | 65.7% |
| 2jnsA01 | 1.20.1270.220 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 47.0 | 4.88e-01 | 87.4% | 85.2% |
| 2nsfA01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.64 | 53.0 | 4.40e-01 | 93.1% | 95.0% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 49.0 | 5.32e-01 | 85.1% | 97.3% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.62 | 49.0 | 3.71e-01 | 83.9% | 81.2% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 55.0 | 4.38e-01 | 100.0% | 73.1% |
| 6elqA01 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.61 | 48.0 | 3.92e-01 | 87.4% | 86.4% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 53.0 | 4.45e-01 | 100.0% | 76.8% |
| 2ix5A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.60 | 54.0 | 4.47e-01 | 100.0% | 73.5% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.59 | 44.0 | 3.74e-01 | 100.0% | 46.4% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 51.0 | 4.29e-01 | 97.7% | 84.5% |
| 5ubvA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 36.0 | 3.91e-01 | 81.6% | 76.1% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.57 | 51.0 | 4.21e-01 | 100.0% | 71.2% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 47.0 | 4.91e-01 | 94.3% | 100.0% |
| 1ywmA02 | 1.20.1270.150 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Surface Active Protein | 0.57 | 40.0 | 4.31e-01 | 75.9% | 85.5% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 49.0 | 4.16e-01 | 100.0% | 88.4% |
| 4gyoB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 37.0 | 3.16e-01 | 73.6% | 41.7% |
| 3a8rA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.57 | 39.0 | 3.61e-01 | 71.3% | 81.4% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 50.0 | 4.00e-01 | 100.0% | 65.1% |
| 4jioA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.56 | 45.0 | 3.80e-01 | 86.2% | 90.9% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.55 | 29.0 | 2.68e-01 | 100.0% | 34.8% |
| 1oizA01 | 1.10.8.20 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p | 0.55 | 34.0 | 3.70e-01 | 79.3% | 75.0% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 42.0 | 3.91e-01 | 82.8% | 75.9% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 41.0 | 3.52e-01 | 100.0% | 49.3% |
| 3tc1B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 40.0 | 2.81e-01 | 79.3% | 44.3% |
| 2w9zA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 46.0 | 4.07e-01 | 100.0% | 73.7% |
| 2hh6A00 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.53 | 36.0 | 3.42e-01 | 87.4% | 56.8% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.52 | 32.0 | 2.83e-01 | 100.0% | 40.6% |
| 7ml0M01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.52 | 38.0 | 3.90e-01 | 90.8% | 82.9% |
| 2cfqA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 45.0 | 3.48e-01 | 100.0% | 85.9% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.51 | 33.0 | 3.39e-01 | 85.1% | 67.1% |
| 1gxyA00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.51 | 44.0 | 3.34e-01 | 98.9% | 91.0% |
| 3rlfG01 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.51 | 38.0 | 2.69e-01 | 79.3% | 71.4% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3867165 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.64 | 50.0 | 4.25e-01 | 83.9% | 61.4% |
| 4926828 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.63 | 56.0 | 4.48e-01 | 100.0% | 81.7% |
| 3962329 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.63 | 56.0 | 4.65e-01 | 100.0% | 74.8% |
| 3687733 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.62 | 55.0 | 4.39e-01 | 100.0% | 72.8% |
| 3406963 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.62 | 48.0 | 3.29e-01 | 83.9% | 80.0% |
| 4114693 | 5041.1.1.28 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26135 | 0.60 | 30.0 | 3.38e-01 | 100.0% | 60.0% |
| 5068844 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.59 | 47.0 | 4.63e-01 | 86.2% | 85.3% |
| 3269226 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.59 | 36.0 | 3.87e-01 | 89.7% | 70.7% |
| 1824764 | 1189.1.1.4 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › HpHbR | 0.59 | 47.0 | 3.37e-01 | 86.2% | 78.7% |
| 4032129 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.59 | 38.0 | 4.36e-01 | 78.2% | 89.2% |
| 3489761 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.57 | 44.0 | 3.32e-01 | 83.9% | 89.3% |
| 4114337 | 632.2.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains | 0.57 | 44.0 | 4.67e-01 | 86.2% | 96.0% |
| 4980482 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.57 | 51.0 | 4.48e-01 | 100.0% | 90.0% |
| 3982976 | 235.1.1.0 ↗ | a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like | 0.57 | 44.0 | 3.94e-01 | 85.1% | 60.8% |
| 3743101 | 1128.1.1.1 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR | 0.57 | 40.0 | 4.30e-01 | 78.2% | 86.7% |
| 3719985 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.55 | 48.0 | 4.57e-01 | 100.0% | 87.6% |
| 3416038 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.54 | 47.0 | 4.21e-01 | 100.0% | 91.5% |
| 3583937 | 3861.1.1.1 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR | 0.54 | 42.0 | 3.97e-01 | 83.9% | 95.2% |
| 3484553 | 5054.1.1.1 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan | 0.54 | 39.0 | 3.36e-01 | 100.0% | 47.9% |
| 3492576 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.53 | 41.0 | 3.23e-01 | 86.2% | 86.5% |
| 2617394 | 3960.1.1.1 ↗ | alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › AadA_C | 0.52 | 39.0 | 3.78e-01 | 80.5% | 80.6% |
| 3942475 | 628.1.1.1 ↗ | alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD | 0.52 | 44.0 | 3.67e-01 | 100.0% | 53.5% |
| 3409326 | 3930.1.1.6 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD | 0.52 | 43.0 | 3.84e-01 | 97.7% | 81.5% |
| 4121314 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.52 | 39.0 | 3.79e-01 | 80.5% | 85.3% |
| 3933323 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 43.0 | 3.99e-01 | 100.0% | 83.3% |
| 3513364 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.51 | 44.0 | 3.75e-01 | 100.0% | 80.0% |
| 3458940 | 101.1.10.38 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF247 | 0.50 | 42.0 | 3.71e-01 | 95.4% | 96.4% |
| 3219995 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.50 | 42.0 | 3.70e-01 | 100.0% | 78.6% |
D2
high
residues 100-234
Domain cluster:
rep: hypothetical_protein_DpV83gp011__YP_227388__Deerpox_virus_W-848-83__305674__D104-238
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06227.18 best | Poxv_Bcl-2-like | 67.7 | 1.50e-18 | 94.1% | 78.2% |