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Amidase

Euk-Vir

Only_Syngen_Nebraska_virus_5

Amidase__YP_009325653__Only_Syngen_Nebraska_virus_5__1917232

Identity

Accession:
YP_009325653 ↗
Protein ID:
Amidase
Kingdom:
euk

Quality

73.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-62_150-173_215-279
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02275.24 best CBAH 28.8 1.40e-06 50.3% 20.2%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pvaA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.83 79.0 5.88e-01 98.7% 90.9%
5hkeA01 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.82 78.0 5.93e-01 98.7% 96.4%
2hezA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.80 76.0 5.78e-01 98.7% 94.6%
6dxwA01 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.69 62.0 5.26e-01 94.0% 100.0%
1f1sA03 2.60.220.10 Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal 0.65 29.0 3.83e-01 100.0% 75.6%
2z13A00 2.30.29.170 Mainly Beta › Roll › PH-domain like › 0.60 25.0 2.88e-01 94.0% 48.7%
1srqA01 3.30.1120.160 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.59 26.0 2.78e-01 99.3% 45.7%
2vzsA05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 28.0 3.39e-01 90.1% 72.3%
1wruA01 2.30.300.10 Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold 0.55 28.0 2.64e-01 88.1% 41.1%
1zq7A01 3.30.700.20 Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Hypothetical protein ph0010; domain 1 0.54 31.0 3.35e-01 94.7% 65.4%
1by5A02 2.40.170.20 Mainly Beta › Beta Barrel › Maltoporin; Chain A › TonB-dependent receptor, beta-barrel domain 0.52 32.0 2.17e-01 100.0% 17.0%
4q28A00 3.30.160.780 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 27.0 3.15e-01 93.4% 70.0%
3esiA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.51 37.0 4.02e-01 100.0% 89.5%
7mhwA01 2.40.128.10 Mainly Beta › Beta Barrel › Lipocalin › 0.51 23.0 2.85e-01 100.0% 66.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4626959 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.84 81.0 6.07e-01 100.0% 91.8%
4031896 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.84 80.0 6.04e-01 100.0% 92.3%
5047706 210.1.2.4 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › AAT 0.71 67.0 5.38e-01 100.0% 98.1%
3604107 210.1.1.4 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › IMP_cyclohyd 0.59 51.0 4.67e-01 93.4% 98.5%
4564828 4026.1.1.1 a+b three layers › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › Rap-GAP_dimer 0.58 27.0 2.72e-01 99.3% 41.9%
4012095 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.56 32.0 3.48e-01 89.4% 65.6%
3578536 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.55 30.0 3.34e-01 90.1% 66.1%
3800797 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.55 30.0 3.34e-01 90.1% 66.1%
3704023 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.55 30.0 3.30e-01 89.4% 64.2%
4028760 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.54 31.0 3.46e-01 89.4% 70.4%
3878264 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.54 30.0 3.46e-01 90.1% 71.8%
3269789 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.54 28.0 3.60e-01 89.4% 87.1%
3490554 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.54 30.0 3.28e-01 89.4% 65.0%
3417419 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.52 29.0 3.08e-01 89.4% 59.2%
3591087 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.52 28.0 3.21e-01 89.4% 67.0%
1298174 260.1.1.1 a+b duplicates or obligate multimers › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › Plectin 0.52 27.0 3.15e-01 93.4% 70.0%
4024840 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.51 28.0 3.02e-01 89.4% 57.8%
3902541 319.1.1.5 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › PIH1_CS 0.50 28.0 3.59e-01 88.7% 96.5%
D2 medium residues 63-149
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02275.24 best CBAH 52.5 8.70e-14 100.0% 26.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oqcA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.92 87.0 5.69e-01 100.0% 27.4%
5hkeA01 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.89 83.0 5.50e-01 100.0% 28.0%
2pvaA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.89 84.0 5.45e-01 100.0% 26.6%
2hezA00 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.87 80.0 5.27e-01 100.0% 27.0%
2bjfA01 3.60.60.10 Alpha Beta › 4-Layer Sandwich › Penicillin V Acylase; Chain A › Penicillin V Acylase; Chain A 0.87 82.0 5.37e-01 100.0% 27.4%
3oe3C00 2.40.128.200 Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor 0.68 32.0 3.19e-01 100.0% 43.2%
1ci3M02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.68 28.0 3.41e-01 96.6% 55.2%
3c4bA02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.62 28.0 3.18e-01 97.7% 52.2%
2m7oA00 3.10.450.400 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Uncharacterised protein PF15513, DUF4651 0.60 39.0 4.31e-01 80.5% 82.9%
1e0bA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 26.0 3.07e-01 96.6% 50.8%
3kxyJ00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.59 38.0 3.36e-01 93.1% 44.2%
4obiA00 2.60.320.10 Mainly Beta › Sandwich › mini-chromosome maintenance (MCM) complex, domain 2 › N-utilization substance G protein NusG, insert domain 0.57 35.0 3.50e-01 89.7% 59.8%
2k7iA01 3.30.160.160 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YegP-like 0.56 26.0 3.16e-01 94.3% 66.7%
6g9sA01 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.53 43.0 2.96e-01 92.0% 88.2%
3t0qA00 3.40.850.10 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › Kinesin motor domain 0.52 40.0 2.77e-01 82.8% 89.8%
1iucA00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.52 42.0 2.95e-01 90.8% 93.9%
4lb0A02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.52 44.0 3.70e-01 100.0% 71.3%
4f3nA00 3.40.50.12710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 40.0 2.77e-01 89.7% 85.0%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4031896 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.93 89.0 5.74e-01 100.0% 26.8%
4626959 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.92 87.0 5.64e-01 100.0% 26.5%
7831 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.89 84.0 5.45e-01 100.0% 26.5%
3076049 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.89 83.0 5.39e-01 100.0% 26.1%
349797 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.87 82.0 5.34e-01 100.0% 26.4%
4525386 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.87 82.0 5.40e-01 100.0% 28.5%
3076054 210.1.2.2 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › CBAH 0.85 81.0 5.28e-01 100.0% 27.1%
4349950 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.76 30.0 3.60e-01 96.6% 51.7%
4456732 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.75 30.0 3.14e-01 97.7% 40.0%
4119875 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.75 30.0 3.45e-01 96.6% 47.7%
4435672 325.1.7.0 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.74 30.0 3.44e-01 96.6% 47.7%
4625348 325.1.7.3 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.68 28.0 3.31e-01 96.6% 53.3%
4929797 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.65 29.0 3.44e-01 100.0% 59.3%
3783916 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.64 28.0 3.38e-01 97.7% 60.0%
4890232 5.1.4.34 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup88 0.61 49.0 2.88e-01 86.2% 74.4%
3679761 5.1.5.117 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Nup88 0.60 47.0 2.86e-01 86.2% 81.5%
3922649 391.1.2.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related 0.59 30.0 3.44e-01 93.1% 64.6%
3274001 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.57 45.0 3.09e-01 87.4% 91.9%
3230503 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 46.0 3.57e-01 88.5% 59.5%
3178289 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.55 46.0 3.07e-01 94.3% 78.2%
4031999 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.54 41.0 4.20e-01 97.7% 82.4%
4030191 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.54 44.0 2.63e-01 89.7% 52.2%
167222 391.1.1.1 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › fn1 0.54 30.0 3.49e-01 92.0% 75.4%
3535572 239.3.1.1 beta barrels › Ribosomal protein L25-like › FAS1 domain › FAS1 domain › Fasciclin 0.54 37.0 3.14e-01 70.1% 52.1%
3179728 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.54 45.0 3.00e-01 93.1% 95.9%
3923605 5.1.5.162 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Beta-prop_ACSF4 0.54 45.0 3.00e-01 93.1% 97.8%
5071103 5.1.4.43 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.54 44.0 2.92e-01 90.8% 96.3%
3989854 3761.1.1.4 beta duplicates or obligate multimers › Major tropism determinant (Mtd) trimerization domain-related › Major tropism determinant (Mtd) trimerization domain-related › Major tropism determinant (Mtd) trimerization domain-related › CFSR 0.53 31.0 3.20e-01 83.9% 57.6%
3910972 391.1.1.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module 0.52 35.0 4.13e-01 90.8% 100.0%
3498817 239.3.1.0 beta barrels › Ribosomal protein L25-like › FAS1 domain › FAS1 domain 0.51 35.0 2.85e-01 70.1% 55.2%
3244738 223.2.1.16 a+b three layers › Profilin-like › profilin-like › profilin-like › LAMTOR5 0.51 38.0 3.76e-01 92.0% 74.7%
3848511 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.51 41.0 2.32e-01 87.4% 9.9%
3716096 77.2.1.1 beta meanders › open-sided beta-meander › Histone H3 K4-specific methyltransferase SET7/9-N › Histone H3 K4-specific methyltransferase SET7/9-N › MORN 0.50 33.0 2.87e-01 89.7% 43.0%