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Amidophosphoribosyltransferase

Euk-Vir

Mollivirus_sibericum_Viruses.

Amidophosphoribosyltransferase__YP_009165054__Mollivirus_sibericum_Viruses.__X

Identity

Accession:
YP_009165054 ↗
Protein ID:
Amidophosphoribosyltransferase
Kingdom:
euk

Quality

63.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 289-355_368-487
PDB
D2 medium residues 1-86_198-273
PDB
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6czfA01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.83 74.0 5.69e-01 92.6% 75.4%
1ao0A01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.78 70.0 5.52e-01 92.6% 74.0%
1xffA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.75 70.0 6.03e-01 98.1% 97.9%
4zfjD00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.72 64.0 5.63e-01 92.6% 99.1%
5mj6A03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 30.0 4.21e-01 71.6% 100.0%
3n40P04 2.60.40.2400 Mainly Beta › Sandwich › Immunoglobulin-like › Alphavirus E2 glycoprotein, domain C 0.55 27.0 3.76e-01 88.9% 100.0%
3pjyA00 2.60.120.1140 Mainly Beta › Sandwich › Jelly Rolls › Protein of unknown function DUF192 0.55 31.0 3.44e-01 85.2% 68.2%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 28.0 3.45e-01 91.4% 85.6%
2w5fB01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.51 33.0 3.44e-01 74.1% 69.7%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.51 26.0 3.51e-01 82.7% 98.7%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.50 36.0 3.71e-01 85.8% 77.6%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3741900 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.85 77.0 6.40e-01 93.8% 98.8%
5052100 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.84 76.0 6.38e-01 93.8% 96.8%
3963395 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.83 74.0 6.20e-01 93.2% 97.3%
4321843 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.82 67.0 5.92e-01 84.6% 100.0%
None 0.82 73.0 6.22e-01 92.6% 96.7%
4422215 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.82 68.0 5.93e-01 85.8% 100.0%
3532427 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.82 74.0 6.13e-01 93.8% 99.2%
None 0.81 73.0 6.27e-01 93.2% 97.1%
None 0.81 73.0 6.06e-01 93.8% 98.8%
4947599 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.81 73.0 6.16e-01 93.2% 95.5%
5066749 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 73.0 6.17e-01 93.8% 97.6%
None 0.80 72.0 6.24e-01 93.2% 97.0%
4999227 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 72.0 6.03e-01 93.2% 95.3%
4484517 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 72.0 6.06e-01 93.2% 91.2%
4954583 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 71.0 6.11e-01 92.6% 96.7%
4976794 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 72.0 6.31e-01 94.4% 98.3%
4994995 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 72.0 6.18e-01 93.2% 98.3%
5033976 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.80 72.0 6.14e-01 93.2% 97.9%
5077548 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.79 70.0 5.67e-01 93.8% 98.6%
5071630 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.79 71.0 6.11e-01 93.8% 97.1%
5010284 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.79 71.0 6.34e-01 93.2% 96.7%
3280543 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.79 70.0 5.98e-01 92.6% 97.6%
4981026 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.78 71.0 6.07e-01 93.8% 95.4%
4991572 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.78 70.0 6.01e-01 93.2% 100.0%
5032499 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.78 71.0 6.02e-01 93.8% 98.0%
5041669 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.78 70.0 6.37e-01 93.2% 100.0%
5075402 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.78 71.0 5.77e-01 96.3% 100.0%
4541620 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.77 71.0 5.92e-01 95.1% 95.3%
5024709 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.77 69.0 6.06e-01 92.6% 100.0%
5049285 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.77 69.0 6.04e-01 93.8% 97.4%
4147605 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.77 73.0 6.12e-01 98.8% 96.8%
5081419 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.77 67.0 5.52e-01 91.4% 100.0%
4976025 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.76 72.0 6.13e-01 98.8% 96.3%
5009366 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.76 72.0 5.97e-01 100.0% 100.0%
3942872 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.76 66.0 5.60e-01 92.0% 100.0%
5010282 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.76 69.0 6.44e-01 93.8% 99.5%
4947903 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.76 71.0 6.07e-01 98.8% 96.7%
5070626 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.75 67.0 5.62e-01 92.6% 100.0%
5081628 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.75 71.0 6.00e-01 98.8% 97.2%
3965213 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.75 67.0 5.52e-01 93.8% 93.5%
4940798 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.75 71.0 6.04e-01 98.8% 96.7%
4259223 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.75 71.0 6.12e-01 98.8% 99.1%
3963821 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.75 71.0 5.96e-01 98.8% 94.8%
None 0.75 71.0 6.10e-01 100.0% 100.0%
4149445 210.1.3.4 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_6 0.74 69.0 5.90e-01 98.8% 95.1%
3738959 11.1.1.643 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig-like_POM152 0.56 33.0 4.14e-01 85.8% 96.8%
4936727 304.3.1.4 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › MCR_D 0.52 31.0 3.55e-01 82.1% 80.9%
5043357 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 32.0 3.92e-01 88.9% 97.1%
5007276 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.50 34.0 3.70e-01 74.1% 80.7%
D3 medium residues 87-197
PDB
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6czfA01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.87 76.0 5.26e-01 100.0% 31.5%
7ylzA01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.84 62.0 4.82e-01 100.0% 39.0%
1ao0A01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.83 66.0 4.66e-01 100.0% 30.7%
1te5A00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.71 66.0 4.96e-01 100.0% 60.1%
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 41.0 4.97e-01 78.4% 100.0%
1t98A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 33.0 3.74e-01 86.5% 64.4%
1jgtB01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.62 59.0 4.67e-01 100.0% 64.9%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 27.0 3.26e-01 90.1% 60.3%
3umcD02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.60 41.0 4.76e-01 90.1% 100.0%
5b1oA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.59 29.0 3.68e-01 76.6% 78.5%
5hftD00 3.60.20.40 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Gamma-glutamyltranspeptidase, small (S) subunit 0.59 41.0 3.71e-01 100.0% 52.6%
1yarH00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.58 47.0 3.86e-01 100.0% 47.8%
4apyA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.56 46.0 3.19e-01 91.9% 62.6%
1q5qH00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.56 49.0 3.91e-01 97.3% 56.7%
1wibA00 3.30.1550.10 Alpha Beta › 2-Layer Sandwich › Ribosomal protein L11, N-terminal domain › Ribosomal protein L11/L12, N-terminal domain 0.55 27.0 2.91e-01 74.8% 52.2%
6qm7N00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 49.0 3.94e-01 100.0% 56.4%
6muwJ00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.54 49.0 4.00e-01 99.1% 61.0%
3cjrB01 3.30.1550.10 Alpha Beta › 2-Layer Sandwich › Ribosomal protein L11, N-terminal domain › Ribosomal protein L11/L12, N-terminal domain 0.54 25.0 3.04e-01 91.9% 64.3%
1ryp200 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.53 47.0 3.77e-01 100.0% 54.9%
3rpmA02 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.51 28.0 3.10e-01 86.5% 65.9%
1rypL00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.50 44.0 3.60e-01 98.2% 56.1%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5071630 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.89 72.0 5.43e-01 100.0% 39.2%
4976792 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.88 72.0 6.04e-01 100.0% 54.3%
3973007 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.87 77.0 5.66e-01 100.0% 40.4%
None 0.87 76.0 5.68e-01 100.0% 41.2%
3741900 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.87 76.0 5.57e-01 100.0% 38.8%
3963395 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.86 79.0 5.80e-01 100.0% 41.6%
5013417 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.86 69.0 5.25e-01 100.0% 39.6%
5032499 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.85 69.0 5.17e-01 100.0% 38.4%
3284789 210.1.3.4 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_6 0.84 62.0 4.78e-01 100.0% 37.8%
None 0.83 65.0 4.98e-01 100.0% 38.7%
4100017 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.75 69.0 5.11e-01 100.0% 64.4%
3356117 210.1.3.5 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.75 70.0 4.97e-01 100.0% 51.6%
None 0.73 69.0 4.92e-01 100.0% 55.3%
4944048 210.1.3.3 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.73 68.0 5.15e-01 100.0% 66.5%
3632302 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.64 36.0 4.21e-01 79.3% 76.2%
3721693 210.2.1.1 a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C 0.63 58.0 3.98e-01 100.0% 64.7%
3973889 210.2.1.2 a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › SpoIIE 0.61 55.0 4.25e-01 100.0% 52.2%
4998349 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.57 52.0 4.20e-01 100.0% 58.2%
3959950 2006.1.1.44 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like 0.57 47.0 3.86e-01 89.2% 61.5%
153744 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.56 47.0 3.57e-01 88.3% 51.2%
5000549 230.5.1.0 a+b two layers › T-fold › Band 7/SPFH domain › Band 7/SPFH domain 0.56 46.0 4.57e-01 89.2% 88.7%
3222603 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.56 50.0 3.92e-01 99.1% 51.7%
4967186 2006.1.1.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.55 45.0 3.47e-01 85.6% 52.9%
3439481 3781.1.1.1 a+b two layers › Ribosomal protein L11/L12e N-terminal domain-like › Ribosomal protein L11/L12e N-terminal domain › Ribosomal protein L11/L12e N-terminal domain › Ribosomal_L11_N 0.52 25.0 2.91e-01 73.0% 59.5%
4026202 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.51 33.0 3.71e-01 79.3% 83.3%
5004081 3239.1.1.1 alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 0.50 39.0 2.80e-01 82.0% 45.6%