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Ankyrin_repeat_domain_containing_protein

Euk-Vir

Pandoravirus_macleodensis

Ankyrin_repeat_domain_containing_protein__YP_009481090__Pandoravirus_macleodensis__2107707

Identity

Accession:
YP_009481090 ↗
Protein ID:
Ankyrin_repeat_domain_containing_protein
Kingdom:
euk

Quality

78.5 mean pLDDT

Taxonomy

Pandoravirus› Pandoravirus_macleodensis

TaxID: 2107707

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 71-169
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rfmB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.61 55.0 4.48e-01 100.0% 66.3%
1sw6A00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.59 53.0 3.97e-01 100.0% 62.6%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.57 31.0 2.95e-01 87.9% 42.1%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 40.0 4.01e-01 83.8% 98.1%
7zcvA02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 44.0 3.56e-01 100.0% 62.9%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3246022 109.3.1.33 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_3 0.67 50.0 4.24e-01 79.8% 64.8%
3801796 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.65 49.0 3.57e-01 78.8% 40.8%
3827580 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.63 47.0 4.46e-01 79.8% 89.2%
4619747 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.62 49.0 4.77e-01 93.9% 75.5%
3725739 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.61 55.0 4.24e-01 100.0% 60.4%
3486873 109.3.1.166 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_3 0.61 51.0 4.31e-01 99.0% 55.6%
3677934 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.60 43.0 3.42e-01 94.9% 36.1%
3267275 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.60 53.0 4.30e-01 97.0% 69.2%
3260809 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.59 54.0 4.83e-01 99.0% 80.0%
3465076 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.59 53.0 3.95e-01 100.0% 52.0%
3460576 109.3.1.162 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_5 0.59 47.0 3.53e-01 87.9% 57.3%
4531706 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.59 53.0 4.26e-01 100.0% 76.8%
3421776 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.58 45.0 3.73e-01 83.8% 58.4%
3259554 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.58 53.0 3.99e-01 99.0% 63.0%
3808809 109.3.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.58 51.0 4.43e-01 98.0% 74.8%
3186674 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 52.0 4.53e-01 100.0% 75.3%
3361962 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.57 42.0 3.78e-01 78.8% 71.7%
3804358 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.57 43.0 3.50e-01 81.8% 53.5%
3824397 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.57 43.0 3.50e-01 81.8% 56.0%
3813220 109.4.1.1293 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1 0.57 42.0 3.12e-01 78.8% 38.1%
3438125 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.57 42.0 3.49e-01 78.8% 55.7%
3375347 109.4.1.184 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1 0.56 50.0 4.24e-01 100.0% 73.3%
3814487 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.56 41.0 3.19e-01 78.8% 42.6%
3343060 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.55 43.0 3.67e-01 94.9% 50.3%
3360774 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 44.0 3.89e-01 90.9% 60.0%
3650822 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.54 47.0 4.40e-01 100.0% 87.7%
3824590 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.54 40.0 3.41e-01 78.8% 57.6%
3817989 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 47.0 4.25e-01 100.0% 85.0%
3684300 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.53 45.0 3.50e-01 100.0% 51.0%
3432914 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.53 45.0 3.46e-01 100.0% 51.3%
3657259 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.52 45.0 4.12e-01 100.0% 91.9%
3681426 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.52 45.0 3.30e-01 100.0% 46.8%
3347844 109.4.1.1258 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 0.52 42.0 3.12e-01 90.9% 34.1%
3357017 109.4.1.1258 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 0.51 44.0 3.09e-01 100.0% 33.0%
3314062 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.51 44.0 3.69e-01 100.0% 73.3%
3300324 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.50 44.0 4.01e-01 100.0% 90.4%
3321994 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.50 43.0 3.93e-01 100.0% 85.7%
3832763 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.50 42.0 3.83e-01 98.0% 76.6%
3675462 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.50 43.0 4.02e-01 100.0% 86.2%
3810049 109.4.1.1261 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long 0.50 43.0 3.69e-01 99.0% 72.4%
3364365 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.50 43.0 3.31e-01 100.0% 50.2%
D2 medium residues 170-234
PDB
Domain cluster: rep: Ankyrin_repeat_domain_containing_protein__YP_009482714__Pandoravirus_quercus__2107709__D78-176
D3 medium residues 432-546
PDB
Domain cluster: rep: Ankyrin_repeat_domain_containing_protein__YP_009482714__Pandoravirus_quercus__2107709__D78-176
D4 medium residues 547-637
PDB
Domain cluster: rep: Ankyrin_repeat_domain_containing_protein__YP_009482714__Pandoravirus_quercus__2107709__D78-176
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00023.37 best Ank 17.6 5.20e-03 33.0% 66.7%
D5 medium residues 638-696
PDB
Domain cluster: rep: F-box_domain_containing_protein__YP_008318627__Pandoravirus_dulcis__1349409__D665-721
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qfvC02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.83 74.0 7.17e-01 96.6% 92.3%
4rlyA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.81 72.0 4.42e-01 94.9% 21.4%
3lvqE02 1.25.40.950 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.81 69.0 6.38e-01 93.2% 90.5%
4bszB00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.79 72.0 5.26e-01 100.0% 44.7%
3ehrA02 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.78 69.0 5.42e-01 94.9% 48.3%
3ljnA00 1.25.40.20 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain 0.76 67.0 4.22e-01 100.0% 27.3%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.73 62.0 5.68e-01 98.3% 98.8%
3g0oA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.70 54.0 4.28e-01 84.7% 81.8%
3d7iB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.69 56.0 4.80e-01 91.5% 77.6%
3a0oA02 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.65 54.0 3.42e-01 100.0% 30.1%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 44.0 4.38e-01 78.0% 91.9%
2qw6D00 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.60 53.0 4.70e-01 100.0% 73.3%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 49.0 4.37e-01 91.5% 66.3%
3owaA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 48.0 3.84e-01 98.3% 65.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 47.0 4.11e-01 89.8% 82.8%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.28e-01 91.5% 73.3%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.59 48.0 3.48e-01 100.0% 65.8%
1usyC00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.58 38.0 2.47e-01 78.0% 14.2%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.57 46.0 3.63e-01 91.5% 54.1%
3c2gA02 1.10.10.1630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sys-1 C-terminal domain-like 0.57 46.0 4.51e-01 100.0% 98.5%
1c9bA02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.56 41.0 3.50e-01 81.4% 92.5%
3dfgA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 40.0 4.34e-01 76.3% 97.9%
7clgB03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 3.23e-01 98.3% 68.2%
4kvmA02 1.25.40.1010 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 47.0 3.25e-01 100.0% 31.0%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.54 39.0 3.34e-01 78.0% 74.0%
1aisB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.53 38.0 3.31e-01 78.0% 91.5%
3g2eB00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.52 43.0 3.16e-01 100.0% 87.6%
2or0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 43.0 3.12e-01 96.6% 62.4%
5domA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.51 41.0 3.70e-01 98.3% 97.8%
1l0oC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 29.0 2.96e-01 100.0% 50.9%
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.50 36.0 3.26e-01 83.1% 88.7%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3195802 109.3.1.186 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_5 0.82 74.0 4.71e-01 100.0% 22.3%
3695738 109.3.1.232 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_4, Ank_KRIT1 0.78 71.0 4.19e-01 100.0% 25.7%
3610881 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.76 66.0 4.69e-01 96.6% 35.4%
3976334 4995.1.1.3 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › MlrA_helical 0.67 59.0 5.26e-01 100.0% 89.4%
3671661 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.67 57.0 4.91e-01 100.0% 60.0%
3464055 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.66 56.0 4.83e-01 100.0% 68.0%
3592748 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.64 47.0 4.72e-01 78.0% 91.7%
4940271 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.63 46.0 4.01e-01 78.0% 61.1%
4940179 2.21.1.3 ↗ beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 0.62 46.0 3.37e-01 79.7% 36.3%
4954772 101.1.2.141 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_24 0.62 36.0 3.78e-01 100.0% 61.8%
4941280 7000.1.1.0 ↗ alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.60 43.0 3.33e-01 78.0% 39.3%
4033104 604.15.1.0 ↗ alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.59 44.0 4.31e-01 81.4% 76.9%
4927476 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 48.0 3.74e-01 94.9% 48.3%
3938136 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.59 50.0 4.32e-01 98.3% 89.5%
3943035 639.2.1.0 ↗ alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.58 41.0 4.05e-01 76.3% 96.9%
3173112 1203.1.2.4 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › Vps55 0.57 42.0 3.30e-01 79.7% 69.6%
5011454 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.55 40.0 3.24e-01 78.0% 63.3%
5026703 2004.1.1.76 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.54 46.0 2.89e-01 100.0% 39.7%
4940618 198.1.1.0 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.53 38.0 3.52e-01 79.7% 73.8%
4958393 2004.1.1.76 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.52 44.0 2.72e-01 100.0% 15.0%
2439 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.51 29.0 2.96e-01 100.0% 50.9%