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Ankyrin_repeat_protein

Euk-Vir

Eptesipox_virus

Ankyrin_repeat_protein__YP_009408119__Eptesipox_virus__1329402

Identity

Accession:
YP_009408119 ↗
Protein ID:
Ankyrin_repeat_protein
Kingdom:
euk

Quality

89.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 558-647
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF09372.16 best PRANC 54.3 1.90e-14 92.2% 85.6%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2olcA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.72 49.0 3.45e-01 71.1% 69.0%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 46.0 4.00e-01 75.6% 98.5%
2o1eB01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.63 48.0 4.02e-01 80.0% 100.0%
3ppuB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 38.0 3.56e-01 72.2% 51.3%
3pm0A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.56 50.0 3.20e-01 98.9% 51.4%
1gwcA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 37.0 3.23e-01 70.0% 42.6%
1qr0A01 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.54 33.0 2.93e-01 94.4% 44.0%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 37.0 2.95e-01 85.6% 38.5%
1wu3I00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 42.0 3.60e-01 97.8% 91.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3408014 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.74 40.0 2.94e-01 74.4% 20.9%
3874750 101.1.1.249 alpha arrays › HTH › HTH › Three-helical HTH › SGIII 0.70 43.0 4.57e-01 71.1% 70.0%
3659606 3361.1.1.5 alpha bundles › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › C-terminal Pdr1-activating domain of J-protein Zuo1 › PF28983 0.67 38.0 3.51e-01 74.4% 43.5%
3861590 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.58 53.0 3.72e-01 100.0% 88.7%
3669330 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.55 41.0 4.25e-01 80.0% 100.0%
D2 medium residues 1-155
PDB
Pfam (8)
AccessionNameScoreE-valueQ covHMM cov
PF12796.14 best Ank_2 49.7 6.20e-13 61.9% 96.7%
PF12796.14 Ank_2 47.3 3.50e-12 57.4% 87.8%
PF13857.13 Ank_5 36.4 7.10e-09 36.1% 91.1%
PF13637.13 Ank_4 45.2 1.10e-11 33.6% 100.0%
PF13637.13 Ank_4 27.7 3.60e-06 23.9% 70.0%
PF00023.37 Ank 19.1 1.80e-03 21.9% 90.9%
PF00023.37 Ank 38.6 1.10e-09 20.6% 87.9%
PF13606.13 Ank_3 32.3 9.30e-08 19.4% 90.3%
D3 medium residues 195-325
PDB
Pfam (4)
AccessionNameScoreE-valueQ covHMM cov
PF12796.14 best Ank_2 32.7 1.30e-07 75.6% 91.1%
PF13857.13 Ank_5 28.8 1.70e-06 41.2% 89.3%
PF13637.13 Ank_4 25.7 1.60e-05 36.6% 74.0%
PF00023.37 Ank 15.9 1.80e-02 25.9% 100.0%
D4 medium residues 495-549
PDB
Domain cluster: representative
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hteA03 1.10.167.30 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.77 57.0 4.99e-01 78.2% 58.7%
1ed1A00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.73 60.0 4.64e-01 89.1% 56.1%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 62.0 4.77e-01 96.4% 76.9%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 61.0 4.01e-01 96.4% 43.9%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 60.0 4.61e-01 100.0% 64.2%
1zbpA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 54.0 4.75e-01 94.5% 56.5%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.68 55.0 4.13e-01 87.3% 51.1%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 57.0 4.37e-01 100.0% 66.2%
2lt3A01 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.67 54.0 4.46e-01 89.1% 57.0%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 55.0 4.57e-01 96.4% 60.0%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.67 57.0 4.29e-01 98.2% 66.2%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.66 55.0 4.13e-01 100.0% 51.9%
1d8cA03 1.20.1220.12 Mainly Alpha › Up-down Bundle › Malate Synthase G; Chain: A; Domain 4 › Malate synthase, domain III 0.66 55.0 4.28e-01 100.0% 80.7%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.66 55.0 4.07e-01 98.2% 94.4%
4n5cD06 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 58.0 4.58e-01 100.0% 55.8%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 58.0 4.17e-01 100.0% 36.7%
3lszA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 55.0 4.33e-01 100.0% 73.6%
3i5qA02 1.10.167.20 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › 0.64 47.0 4.21e-01 80.0% 85.2%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 51.0 4.18e-01 90.9% 81.7%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.64 52.0 4.13e-01 96.4% 64.1%
3k49A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 52.0 3.25e-01 100.0% 18.7%
3vadA01 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.63 50.0 3.63e-01 89.1% 87.2%
3k7xA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.63 52.0 3.28e-01 100.0% 27.4%
3hgtA00 3.40.50.12360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 51.0 3.25e-01 92.7% 72.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.62 49.0 4.04e-01 94.5% 59.5%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 49.0 4.40e-01 94.5% 70.6%
3feyA02 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 50.0 3.58e-01 100.0% 32.8%
3bniB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 52.0 3.71e-01 98.2% 49.1%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 50.0 3.83e-01 98.2% 61.2%
2wsiA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.61 52.0 3.28e-01 96.4% 53.7%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.60 51.0 3.78e-01 100.0% 51.6%
4b94A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 50.0 3.86e-01 100.0% 51.1%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 48.0 4.20e-01 96.4% 67.7%
8alzB08 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.58 49.0 3.78e-01 98.2% 90.8%
4s2rQ03 3.90.230.10 Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily 0.58 48.0 3.13e-01 100.0% 94.6%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 47.0 3.73e-01 92.7% 55.8%
1e3gA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.56 43.0 2.96e-01 94.5% 42.4%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.53 42.0 3.04e-01 100.0% 73.6%
1wgwA00 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.51 43.0 3.66e-01 100.0% 83.8%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.51 41.0 3.62e-01 90.9% 61.6%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3588414 2004.1.1.430 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, ABC_tran_Xtn 0.84 59.0 3.32e-01 72.7% 8.0%
3303026 109.4.1.1254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif 0.76 69.0 4.00e-01 100.0% 15.4%
3170098 109.4.1.1362 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_C 0.76 68.0 4.25e-01 100.0% 40.3%
3626611 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 66.0 3.90e-01 100.0% 16.3%
3221271 3948.1.1.0 alpha bundles › V(D)J recombination-activating protein 1 helical bundle domain › V(D)J recombination-activating protein 1 helical bundle domain › V(D)J recombination-activating protein 1 helical bundle domain 0.73 64.0 4.61e-01 94.5% 38.6%
3479016 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 62.0 3.96e-01 100.0% 27.5%
3644609 109.4.1.2210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30701 0.72 61.0 3.65e-01 100.0% 17.2%
3719990 109.4.1.1264 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_16 0.72 64.0 4.36e-01 100.0% 31.6%
5073131 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.71 61.0 4.75e-01 96.4% 60.8%
3605559 604.9.1.0 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 0.71 60.0 4.88e-01 96.4% 55.0%
3643878 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 62.0 3.93e-01 100.0% 28.4%
3686594 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 62.0 5.46e-01 98.2% 82.5%
3705324 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.69 59.0 5.25e-01 96.4% 75.0%
3600392 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 61.0 3.91e-01 100.0% 28.7%
3634846 109.4.1.1672 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PUF, CPL 0.69 60.0 3.44e-01 100.0% 12.4%
4032384 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.69 57.0 5.06e-01 92.7% 81.2%
3603137 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 55.0 4.07e-01 96.4% 47.3%
3479454 109.4.1.911 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG6_C 0.68 57.0 3.33e-01 100.0% 22.0%
3896763 101.1.1.66 alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_5 0.66 49.0 4.26e-01 80.0% 69.4%
3722903 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 56.0 3.72e-01 100.0% 35.9%
5009775 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.66 58.0 4.83e-01 100.0% 61.1%
4364111 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 57.0 4.41e-01 100.0% 53.6%
4527327 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 53.0 3.87e-01 100.0% 56.6%
3687448 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 50.0 3.42e-01 94.5% 31.2%
3328228 601.33.1.7 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › Exo70_N 0.63 52.0 4.62e-01 96.4% 71.8%
3269677 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 53.0 3.91e-01 96.4% 54.0%
4582542 192.11.1.1 alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › UVR 0.62 50.0 4.83e-01 90.9% 90.5%
3608506 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 52.0 3.43e-01 100.0% 45.1%
3596728 283.1.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase 0.62 49.0 3.17e-01 92.7% 92.8%
3622849 109.4.1.218 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.60 49.0 3.21e-01 100.0% 25.3%
3581262 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 47.0 4.17e-01 96.4% 92.2%
3667215 109.1.1.37 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_N_2 0.59 47.0 3.35e-01 100.0% 43.7%
3722750 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.59 50.0 3.11e-01 96.4% 54.4%
3682803 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 49.0 3.39e-01 100.0% 54.8%
3516803 109.25.1.1 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN 0.58 49.0 3.87e-01 100.0% 73.6%
5073302 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.58 47.0 3.57e-01 92.7% 44.3%
4547254 7512.1.1.1 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.58 51.0 3.43e-01 100.0% 67.1%
4050574 192.17.1.11 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › UVR 0.58 49.0 4.49e-01 98.2% 70.7%
4322883 601.13.1.11 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FlaF 0.54 44.0 3.80e-01 100.0% 73.0%