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Archaeal_DNA_polymerase_I

Euk-Vir

Kaumoebavirus_Viruses.

Archaeal_DNA_polymerase_I__YP_009352507__Kaumoebavirus_Viruses.__X

Identity

Accession:
YP_009352507 ↗
Protein ID:
Archaeal_DNA_polymerase_I
Kingdom:
euk

Quality

65.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-187
PDB
D2 high residues 1251-1350
PDB
D3 medium residues 189-267_288-373_387-412
PDB
D4 medium residues 268-287_413-506
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 51.0 3.78e-01 82.5% 26.9%
1vq8V00 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 39.0 5.01e-01 76.3% 96.9%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 43.0 5.03e-01 70.2% 93.5%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 44.0 5.20e-01 91.2% 100.0%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.64 45.0 3.25e-01 72.8% 68.8%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.64 44.0 4.27e-01 75.4% 63.2%
1vmgA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.63 33.0 3.79e-01 71.1% 68.3%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.63 43.0 4.06e-01 70.2% 59.3%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 39.0 4.71e-01 74.6% 98.6%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 38.0 4.62e-01 74.6% 97.2%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.61 44.0 4.63e-01 74.6% 90.2%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 45.0 4.80e-01 82.5% 88.8%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 52.0 5.03e-01 93.0% 100.0%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 39.0 4.47e-01 70.2% 91.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.61 42.0 4.62e-01 70.2% 90.0%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 40.0 4.71e-01 78.1% 98.7%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 41.0 4.65e-01 72.8% 96.3%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 36.0 4.49e-01 71.9% 100.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 39.0 4.10e-01 80.7% 73.5%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 44.0 3.43e-01 77.2% 38.8%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.60 43.0 4.76e-01 75.4% 94.4%
2yxhA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.59 35.0 3.53e-01 71.1% 57.5%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.58 38.0 4.51e-01 75.4% 100.0%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 41.0 3.21e-01 77.2% 33.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 47.0 4.99e-01 86.0% 100.0%
3htkC01 1.20.120.1010 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 42.0 3.48e-01 77.2% 42.5%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 38.0 4.53e-01 74.6% 100.0%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.57 48.0 4.84e-01 92.1% 97.4%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 40.0 4.08e-01 73.7% 94.7%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 41.0 4.42e-01 94.7% 89.7%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 40.0 3.45e-01 74.6% 76.6%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 39.0 3.31e-01 72.8% 72.5%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 47.0 3.78e-01 93.0% 55.9%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.55 36.0 3.78e-01 74.6% 74.7%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 43.0 4.40e-01 90.4% 98.2%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 43.0 4.37e-01 91.2% 94.7%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 43.0 4.42e-01 91.2% 98.1%
6tkyA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.52 40.0 3.96e-01 87.7% 77.9%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.52 39.0 2.65e-01 78.9% 25.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.52 35.0 3.97e-01 77.2% 92.9%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.52 37.0 3.69e-01 87.7% 72.4%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 4.21e-01 86.0% 96.2%
3n3dB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.09e-01 89.5% 48.2%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 36.0 3.65e-01 78.9% 75.0%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.50 28.0 3.22e-01 88.6% 75.3%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5029513 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.71 43.0 5.39e-01 84.2% 100.0%
5029994 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.71 41.0 5.24e-01 79.8% 100.0%
4445940 192.4.1.1 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 0.70 44.0 5.26e-01 80.7% 98.6%
4953182 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.68 51.0 4.39e-01 82.5% 50.6%
3710592 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.67 44.0 4.75e-01 78.9% 78.9%
3824276 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 49.0 4.18e-01 75.4% 53.3%
3669701 603.1.1.160 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 14-3-3 0.67 43.0 4.34e-01 78.1% 64.3%
3186867 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 45.0 4.02e-01 80.7% 50.9%
4969098 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.64 44.0 3.81e-01 70.2% 48.6%
3941012 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.63 48.0 3.36e-01 80.7% 38.5%
3261777 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.63 46.0 3.66e-01 75.4% 69.8%
5053017 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 44.0 4.11e-01 80.7% 58.6%
3929220 109.4.1.63 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAP42 0.63 52.0 4.10e-01 88.6% 48.3%
3602521 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.62 44.0 3.99e-01 73.7% 81.9%
3708098 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 47.0 3.57e-01 78.9% 40.4%
3634169 4177.1.1.27 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_4 0.61 46.0 3.43e-01 77.2% 33.1%
3884763 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 51.0 4.73e-01 90.4% 89.7%
4681339 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 42.0 3.75e-01 71.1% 92.9%
4935068 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.61 40.0 4.67e-01 74.6% 100.0%
5042955 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.61 47.0 3.01e-01 82.5% 61.0%
3223128 109.4.1.63 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAP42 0.61 51.0 4.05e-01 90.4% 47.1%
3611632 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.60 42.0 4.46e-01 77.2% 82.0%
4209793 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.60 43.0 3.62e-01 73.7% 65.3%
5081955 3834.1.1.25 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.60 46.0 3.47e-01 80.7% 99.3%
3598781 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.60 46.0 3.45e-01 82.5% 37.2%
3596479 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 43.0 4.13e-01 74.6% 87.7%
5054469 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.59 43.0 4.43e-01 74.6% 94.3%
3849660 11.2.1.25 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › PL48 0.59 43.0 4.11e-01 79.8% 65.4%
3772767 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.59 45.0 4.42e-01 80.7% 73.6%
5054107 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 51.0 4.01e-01 94.7% 89.8%
3553813 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.59 45.0 4.41e-01 80.7% 73.6%
3734058 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.59 48.0 5.00e-01 98.2% 97.1%
3574255 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.58 46.0 4.34e-01 82.5% 88.9%
3536875 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 43.0 3.23e-01 77.2% 69.8%
3929097 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.58 52.0 5.04e-01 99.1% 100.0%
3406938 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.58 47.0 4.00e-01 87.7% 91.1%
3752758 3755.3.1.467 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.58 41.0 3.80e-01 73.7% 57.7%
3258119 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.58 44.0 3.59e-01 82.5% 86.7%
3701413 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.57 44.0 3.73e-01 80.7% 63.7%
3904130 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.57 38.0 3.76e-01 70.2% 63.3%
3504339 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.57 47.0 4.80e-01 90.4% 100.0%
4031740 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.56 34.0 3.82e-01 74.6% 79.8%
4947573 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.56 47.0 3.43e-01 89.5% 39.0%
3393794 3922.1.1.211 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C 0.56 42.0 3.97e-01 78.9% 81.5%
3574952 604.28.1.0 alpha bundles › Spectrin repeat-like › E3 ubiquitin-protein ligase SHPRH second helical domain › E3 ubiquitin-protein ligase SHPRH second helical domain 0.55 48.0 3.90e-01 94.7% 81.9%
4034092 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.55 35.0 4.16e-01 76.3% 100.0%
4005523 3860.1.1.167 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin 0.54 40.0 3.64e-01 78.9% 94.4%
3921192 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 44.0 4.39e-01 89.5% 98.3%
3484074 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.54 41.0 3.88e-01 80.7% 66.4%
3584061 604.1.1.136 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_7 0.53 44.0 4.54e-01 92.1% 100.0%
4235305 633.7.1.14 alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like › MG280 0.53 42.0 4.47e-01 86.0% 99.0%
3271624 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.53 41.0 2.77e-01 80.7% 26.4%
3392594 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 41.0 4.25e-01 87.7% 93.6%
D5 medium residues 507-559_597-607_689-782
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 23.1 4.20e-05 32.3% 8.4%
D6 medium residues 582-596_783-920
PDB
CATH (67)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jcmH04 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.77 40.0 5.46e-01 75.2% 98.7%
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.76 43.0 4.77e-01 94.1% 69.7%
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.72 68.0 6.13e-01 97.4% 96.4%
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 38.0 5.20e-01 74.5% 100.0%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 32.0 4.67e-01 71.2% 98.5%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.70 46.0 4.95e-01 76.5% 76.9%
4qbuA03 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.70 32.0 4.69e-01 90.2% 100.0%
4x0qA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 45.0 4.64e-01 88.2% 69.2%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 38.0 5.02e-01 77.8% 100.0%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.69 39.0 4.97e-01 88.2% 97.6%
1d5aA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.68 51.0 5.02e-01 77.1% 84.1%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 42.0 5.25e-01 88.9% 100.0%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 39.0 5.05e-01 90.2% 100.0%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 43.0 5.17e-01 94.1% 95.1%
2fgcA03 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.67 31.0 4.19e-01 86.3% 84.2%
2f1fA02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.67 32.0 4.25e-01 86.3% 85.9%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.67 38.0 3.74e-01 89.5% 50.9%
6yiiA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 57.0 5.16e-01 92.8% 82.3%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.66 39.0 4.93e-01 72.5% 100.0%
2ia0B02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.65 39.0 4.77e-01 82.4% 91.9%
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 38.0 4.87e-01 73.9% 100.0%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.65 34.0 3.73e-01 85.6% 60.3%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 31.0 3.98e-01 72.5% 78.8%
1x60A01 3.30.70.1070 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat 0.64 32.0 4.40e-01 83.0% 100.0%
1weyA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 38.0 4.44e-01 90.8% 84.6%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 40.0 4.87e-01 75.8% 100.0%
1jqgA01 3.30.70.340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like 0.64 35.0 4.32e-01 92.2% 87.9%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.63 31.0 4.12e-01 86.3% 89.6%
4p6qA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 34.0 4.40e-01 81.7% 100.0%
5kfnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 57.0 5.44e-01 98.0% 96.6%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 53.0 5.20e-01 92.2% 84.7%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.62 33.0 4.19e-01 72.5% 89.5%
6d9mA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 52.0 5.23e-01 88.2% 97.4%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.61 45.0 4.90e-01 77.8% 89.2%
1m1hA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.61 38.0 4.54e-01 96.7% 93.0%
3hvaA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 51.0 5.06e-01 88.2% 87.7%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 39.0 4.68e-01 76.5% 98.0%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 51.0 5.18e-01 88.2% 94.6%
4dpoB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 39.0 4.73e-01 84.3% 99.0%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 39.0 4.67e-01 88.2% 99.0%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.60 52.0 4.82e-01 93.5% 88.3%
4kr6A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.60 45.0 4.32e-01 100.0% 68.4%
3r5gA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.60 52.0 4.79e-01 94.1% 89.7%
3hvwA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.60 51.0 5.10e-01 92.2% 91.2%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 37.0 4.53e-01 74.5% 99.0%
2wz1B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.59 52.0 4.78e-01 94.8% 91.8%
2qyxB01 3.30.70.1360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › mj0159-like 0.59 35.0 4.05e-01 81.0% 81.7%
2lu2A00 3.30.70.2380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 32.0 4.24e-01 83.0% 100.0%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.59 41.0 4.65e-01 94.1% 94.8%
3h7hB00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.59 36.0 4.39e-01 81.0% 97.9%
2qv6A01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 46.0 4.96e-01 87.6% 97.7%
2c5sA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.58 43.0 4.19e-01 97.4% 69.2%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 51.0 4.44e-01 95.4% 97.9%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.56 49.0 4.61e-01 94.1% 86.1%
3c0wA02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.56 29.0 3.48e-01 89.5% 73.8%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 35.0 4.16e-01 76.5% 97.9%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.56 29.0 3.87e-01 70.6% 100.0%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.55 44.0 4.66e-01 91.5% 96.2%
3zieD00 3.30.110.150 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein 0.55 24.0 3.14e-01 92.8% 70.7%
6ifnA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.54 45.0 4.41e-01 88.9% 91.7%
1s12A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.54 31.0 3.88e-01 84.3% 92.6%
3mcsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 48.0 4.28e-01 98.0% 87.5%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.53 47.0 4.62e-01 95.4% 88.5%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.53 35.0 4.06e-01 76.5% 98.1%
2v1nA01 1.10.10.2030 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain 0.52 27.0 3.26e-01 79.7% 74.3%
3f44A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 46.0 4.17e-01 98.0% 91.4%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.51 28.0 3.17e-01 86.9% 69.3%
ECOD (84)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4003030 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.78 48.0 6.05e-01 85.0% 100.0%
3530700 4.1.1.331 beta barrels › SH3 › SH3 › SH3 › DUF4708 0.77 43.0 5.69e-01 79.1% 98.8%
3965497 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.77 48.0 5.96e-01 93.5% 100.0%
4566363 304.120.1.18 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › Inhibitor_I9 0.77 39.0 5.42e-01 91.5% 100.0%
None 0.76 72.0 4.53e-01 97.4% 37.5%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.76 71.0 4.45e-01 96.7% 35.8%
3480546 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.76 71.0 5.70e-01 96.7% 94.0%
None 0.76 70.0 4.42e-01 95.4% 36.6%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 70.0 4.44e-01 96.1% 37.2%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.75 71.0 4.39e-01 98.0% 35.2%
3471440 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.75 41.0 5.40e-01 76.5% 96.5%
5050501 3715.1.1.1 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.75 42.0 5.29e-01 85.6% 89.5%
3856783 304.7.1.23 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › DUF4708 0.75 42.0 5.54e-01 78.4% 100.0%
3349591 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.74 69.0 5.35e-01 96.1% 75.5%
5023065 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.73 40.0 5.25e-01 77.1% 96.5%
5012335 304.4.1.29 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 0.73 41.0 4.82e-01 76.5% 79.0%
4975915 304.4.1.29 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 0.73 40.0 5.14e-01 76.5% 92.2%
3603014 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.72 41.0 5.39e-01 77.8% 100.0%
5068786 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.72 44.0 5.43e-01 85.0% 96.8%
3504994 304.163.1.1 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 0.72 42.0 5.15e-01 82.4% 89.9%
3552754 304.163.1.1 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain › R1_ABCA1 0.71 38.0 5.09e-01 76.5% 100.0%
5010510 304.8.1.21 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 0.70 37.0 5.03e-01 75.2% 98.8%
3617015 304.120.1.12 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › PF26955 0.70 40.0 5.16e-01 83.7% 100.0%
3504997 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.70 40.0 5.15e-01 75.8% 100.0%
5035705 304.57.1.0 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.70 40.0 5.09e-01 94.8% 100.0%
4682115 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.69 41.0 5.23e-01 89.5% 100.0%
4940473 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.69 41.0 5.17e-01 78.4% 100.0%
3405197 304.7.1.1 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 0.69 34.0 4.65e-01 75.2% 91.3%
3297930 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.68 41.0 5.14e-01 75.8% 100.0%
3741560 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.68 62.0 5.06e-01 96.7% 80.4%
3578106 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.68 63.0 5.03e-01 96.7% 78.5%
3831499 304.48.1.63 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B, DUF1744 0.68 60.0 3.76e-01 93.5% 29.0%
4118092 304.28.1.4 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.68 35.0 4.72e-01 75.2% 100.0%
3795359 304.8.1.54 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_13 0.67 37.0 4.82e-01 74.5% 100.0%
3703843 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.67 38.0 4.93e-01 90.8% 100.0%
3599389 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 59.0 5.26e-01 92.8% 99.0%
4979323 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.67 38.0 4.78e-01 75.8% 93.3%
5054303 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.67 36.0 4.80e-01 75.2% 100.0%
3926710 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.67 58.0 5.33e-01 92.2% 99.5%
4209732 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.66 41.0 5.13e-01 75.8% 100.0%
4931425 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.66 43.0 4.98e-01 94.8% 90.9%
5035005 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.66 43.0 5.14e-01 94.1% 97.1%
4986705 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.66 43.0 4.94e-01 94.8% 90.9%
4956505 304.57.1.0 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.66 40.0 4.71e-01 94.8% 87.6%
3594154 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 37.0 4.45e-01 83.0% 85.0%
3802360 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.64 45.0 5.04e-01 96.1% 93.9%
3550678 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.64 57.0 5.38e-01 93.5% 83.3%
3404332 304.7.1.1 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 0.64 34.0 4.31e-01 90.8% 86.7%
5177 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.64 41.0 4.85e-01 77.1% 97.0%
3646906 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 39.0 4.81e-01 84.3% 100.0%
4964850 304.48.1.22 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.63 49.0 5.39e-01 88.9% 99.2%
3602746 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 34.0 4.47e-01 75.2% 100.0%
5000281 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.62 36.0 4.56e-01 83.7% 100.0%
3394715 304.7.1.1 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 0.62 34.0 4.34e-01 94.1% 94.1%
4946181 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.62 46.0 5.13e-01 93.5% 98.3%
4269228 304.122.1.1 a+b two layers › Alpha-beta plaits › Nitrogen repressor-like proteins › Nitrogen repressor-like proteins › NRD1_2 0.62 36.0 4.07e-01 79.7% 76.4%
5011278 304.48.1.22 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.62 43.0 5.01e-01 87.6% 100.0%
3413344 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.61 54.0 4.60e-01 94.1% 72.5%
3955607 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.61 40.0 4.72e-01 82.4% 100.0%
3215476 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.60 39.0 4.64e-01 73.9% 100.0%
3987638 304.48.1.49 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_GdpP 0.59 49.0 4.95e-01 90.8% 88.7%
4385553 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.59 49.0 4.83e-01 87.6% 84.8%
3947661 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.59 54.0 5.22e-01 100.0% 91.4%
3857666 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.59 33.0 4.25e-01 70.6% 98.8%
4094511 304.48.1.22 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.58 42.0 4.77e-01 89.5% 100.0%
4579829 304.48.1.49 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_GdpP 0.58 47.0 4.79e-01 91.5% 88.7%
3289349 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.57 50.0 4.46e-01 93.5% 77.2%
3712842 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 49.0 4.66e-01 92.8% 92.8%
3716499 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 49.0 4.32e-01 93.5% 70.7%
3593319 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 51.0 4.84e-01 98.7% 87.6%
2455618 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.57 41.0 4.40e-01 90.8% 88.3%
3607160 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.56 49.0 3.95e-01 93.5% 55.9%
3773041 304.161.1.2 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in TMEM16 lipid scramblase › Alpha-beta plait domain in TMEM16 lipid scramblase › Anoct_dimer 0.56 50.0 4.95e-01 95.4% 96.9%
3444485 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.56 33.0 4.21e-01 73.2% 100.0%
3173046 304.162.1.2 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › FLAD1_M 0.56 34.0 4.11e-01 94.8% 100.0%
4870414 304.161.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in TMEM16 lipid scramblase › Alpha-beta plait domain in TMEM16 lipid scramblase › Anoctamin_N 0.56 45.0 4.71e-01 85.0% 98.5%
4372180 304.48.1.49 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_GdpP 0.55 44.0 4.49e-01 90.2% 87.3%
4993425 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.54 40.0 3.65e-01 77.1% 100.0%
3280191 304.4.1.7 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Cyclase_polyket 0.54 37.0 4.23e-01 75.8% 100.0%
3699931 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.54 49.0 4.67e-01 100.0% 93.9%
3959139 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.52 41.0 4.20e-01 89.5% 85.3%
3608511 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.52 34.0 4.03e-01 71.2% 100.0%
3958967 304.154.1.0 a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain 0.52 41.0 4.16e-01 89.5% 85.3%
3701227 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.52 35.0 4.06e-01 77.1% 99.0%
D7 medium residues 924-1089
PDB
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.77 60.0 6.23e-01 98.2% 88.2%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.76 60.0 6.02e-01 97.6% 80.8%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.76 62.0 6.37e-01 98.2% 88.7%
3k59A07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.73 55.0 5.87e-01 97.6% 90.8%
2gv9B06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.71 66.0 6.14e-01 99.4% 89.7%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3514097 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 62.0 6.17e-01 97.6% 81.8%
3314223 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 61.0 6.28e-01 97.6% 86.9%
3705557 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 61.0 6.24e-01 97.6% 88.7%
3169738 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 61.0 6.14e-01 97.6% 85.5%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.74 60.0 5.70e-01 97.6% 72.7%
4956225 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.74 58.0 6.16e-01 99.4% 93.8%
5002819 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.73 60.0 6.10e-01 97.6% 88.1%
1821876 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.71 66.0 6.14e-01 99.4% 89.7%
5069335 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.69 56.0 5.78e-01 97.6% 90.3%
4944523 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.69 55.0 5.73e-01 95.8% 92.0%
4221968 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.69 64.0 6.15e-01 100.0% 96.8%
3178384 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.68 64.0 6.17e-01 100.0% 95.1%
4030147 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.68 63.0 5.96e-01 100.0% 96.9%
3185070 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.67 63.0 6.07e-01 100.0% 96.2%
4507132 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.67 61.0 5.66e-01 99.4% 97.6%