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BALF5

Euk-Vir

Lymphocryptovirus_Macaca_pfe-lcl-E3

BALF5__YP_010084701__Lymphocryptovirus_Macaca_pfe-lcl-E3__1716044

Identity

Accession:
YP_010084701 ↗
Protein ID:
BALF5
Kingdom:
euk

Quality

85.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Lymphocryptovirus› macacine_gammaherpesvirus_10

TaxID: 1716044

Cluster

View cluster (158 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 162-229
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 59.0 5.21e-01 100.0% 64.7%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 58.0 5.10e-01 100.0% 64.4%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 51.0 4.75e-01 100.0% 66.3%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.65 43.0 3.98e-01 70.6% 52.2%
4qclA02 3.30.70.2820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 53.0 4.57e-01 100.0% 57.7%
1gpmA03 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.63 55.0 4.78e-01 100.0% 76.9%
2gx8A02 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 53.0 4.80e-01 100.0% 71.7%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 50.0 4.49e-01 100.0% 62.6%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 52.0 4.62e-01 100.0% 68.2%
3ue2A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 52.0 4.76e-01 100.0% 71.6%
3g2eB00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.62 54.0 3.98e-01 100.0% 82.7%
2d7vB00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.61 51.0 4.11e-01 100.0% 54.2%
2e8eA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.61 52.0 4.27e-01 100.0% 62.1%
4fvmA02 3.30.70.2820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 51.0 4.58e-01 100.0% 67.0%
2onfA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.60 51.0 4.22e-01 100.0% 61.2%
2bjoA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.59 52.0 4.71e-01 100.0% 81.9%
4ga6A04 3.90.1170.30 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Pyrimidine nucleoside phosphorylase-like, C-terminal domain 0.59 45.0 4.34e-01 97.1% 71.6%
4mh4A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.59 50.0 4.59e-01 100.0% 83.0%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.58 49.0 3.90e-01 100.0% 47.4%
2cz4A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 50.0 4.41e-01 100.0% 66.7%
1a6aB01 3.10.320.10 Alpha Beta › Roll › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 0.56 38.0 3.54e-01 70.6% 74.2%
1nbwA02 3.90.470.30 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Coenzyme B12-Dependent Enzyme linker domain 0.55 37.0 3.02e-01 70.6% 57.3%
2rhqB05 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.55 49.0 3.49e-01 100.0% 78.4%
1v1qA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 40.0 3.50e-01 80.9% 66.4%
1w7cA03 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 43.0 3.75e-01 92.6% 81.7%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.53 47.0 4.12e-01 100.0% 76.5%
1dq3A03 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.53 47.0 4.35e-01 100.0% 78.2%
1yqzA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.53 39.0 3.43e-01 91.2% 50.9%
4e72A01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.53 39.0 3.27e-01 80.9% 49.2%
3bzwF00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.53 36.0 2.47e-01 70.6% 60.1%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.53 45.0 3.98e-01 100.0% 75.2%
1tu5A02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 44.0 3.73e-01 100.0% 66.9%
1ffyA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 42.0 2.68e-01 94.1% 38.5%
3od1A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 44.0 2.93e-01 100.0% 81.9%
4cbgD02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 41.0 3.02e-01 100.0% 34.8%
3s5tA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.51 36.0 2.87e-01 75.0% 42.5%
4fx9A03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.51 41.0 3.56e-01 95.6% 54.9%
1d6uA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.51 42.0 2.73e-01 100.0% 91.7%
4a18X01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.51 36.0 3.50e-01 77.9% 69.6%
3cgbA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.51 41.0 3.59e-01 97.1% 57.3%
1cx8A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.51 42.0 2.85e-01 100.0% 37.5%
1nhpA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.50 41.0 3.54e-01 95.6% 55.8%
3icsA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 44.0 3.00e-01 100.0% 51.6%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4931230 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.83 66.0 5.92e-01 100.0% 63.3%
3206356 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.82 75.0 4.54e-01 100.0% 19.0%
4025112 304.114.1.2 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.82 74.0 6.48e-01 100.0% 77.0%
3638400 304.114.1.2 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.82 74.0 5.99e-01 100.0% 60.8%
3932594 304.114.1.2 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.77 68.0 6.01e-01 100.0% 78.0%
3579169 304.114.1.2 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.76 68.0 5.97e-01 100.0% 75.0%
3214818 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.76 67.0 4.18e-01 100.0% 21.1%
3800859 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.75 67.0 4.78e-01 100.0% 37.5%
4961842 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.75 62.0 5.73e-01 100.0% 71.8%
5000967 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.66 58.0 5.02e-01 100.0% 63.8%
3593809 304.31.1.0 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase 0.66 55.0 4.77e-01 95.6% 89.1%
3622254 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.65 56.0 4.66e-01 100.0% 73.6%
5022277 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.64 44.0 3.63e-01 73.5% 41.5%
3552839 11.1.1.795 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › FANCAA 0.64 55.0 4.68e-01 95.6% 73.6%
5037829 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.64 56.0 4.93e-01 100.0% 67.0%
2579238 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.63 54.0 4.22e-01 100.0% 51.0%
4997962 304.139.1.2 ↗ a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › RAMPs 0.62 53.0 3.65e-01 100.0% 62.3%
4954522 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.62 52.0 4.71e-01 95.6% 79.8%
3271185 304.12.1.5 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MBTP1_N 0.61 53.0 4.82e-01 100.0% 73.7%
3225904 7084.1.1.1 ↗ few secondary structure elements › Highly disulfide-linked beta sandwich region of p43 › Highly disulfide-linked beta sandwich region of p43 › Highly disulfide-linked beta sandwich region of p43 › PF28734 0.61 41.0 3.74e-01 70.6% 70.5%
3969252 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.61 51.0 4.17e-01 97.1% 54.1%
5038748 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.60 50.0 4.26e-01 97.1% 62.5%
4903241 327.3.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain › GMP_synt_C 0.60 45.0 4.09e-01 83.8% 69.1%
3225950 304.126.1.1 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.59 48.0 4.08e-01 100.0% 52.5%
4979129 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.59 50.0 3.95e-01 97.1% 51.7%
4444494 4956.1.1.0 ↗ a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.59 46.0 4.22e-01 100.0% 63.2%
4858920 304.4.1.23 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Dyp_perox_C 0.59 49.0 4.42e-01 97.1% 67.3%
3350776 304.5.1.23 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › V_ATPase_I 0.59 49.0 4.67e-01 100.0% 80.0%
5062402 314.1.1.11 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta 0.58 51.0 3.96e-01 100.0% 90.3%
4255094 304.28.1.35 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Amnionless 0.58 50.0 4.32e-01 100.0% 61.8%
5070432 314.1.1.11 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta 0.56 49.0 3.67e-01 100.0% 77.2%
4797685 304.126.1.1 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.56 47.0 4.00e-01 100.0% 56.6%
4963974 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.56 45.0 2.99e-01 95.6% 25.1%
4979007 324.1.1.1 ↗ a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.56 46.0 3.78e-01 98.5% 55.7%
4635290 4967.1.1.25 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Intron_maturas2+MatK_N 0.56 47.0 2.96e-01 100.0% 17.7%
3435653 4020.1.1.0 ↗ a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes 0.55 37.0 3.50e-01 70.6% 62.4%
3386672 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.55 47.0 4.03e-01 100.0% 67.0%
4990821 7571.1.1.1 ↗ a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N 0.55 46.0 3.18e-01 100.0% 95.3%
5083453 304.139.1.3 ↗ a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › Cas_Cas7 0.55 46.0 3.09e-01 100.0% 63.7%
4862327 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.54 47.0 4.35e-01 100.0% 88.6%
3370992 304.48.1.21 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C 0.54 47.0 2.87e-01 100.0% 16.6%
3592295 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 43.0 3.35e-01 91.2% 83.1%
3592572 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.53 42.0 3.77e-01 91.2% 76.0%
5071965 512.1.1.1 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › PmbA_TldD_1st 0.53 41.0 3.78e-01 88.2% 78.9%
3249666 7541.1.1.1 ↗ a/b three-layered sandwiches › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › Molybdenum cofactor biosynthesis proteins › MoCF_biosynth 0.52 41.0 2.99e-01 88.2% 92.9%
4944561 512.1.1.0 ↗ a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.52 40.0 3.59e-01 86.8% 70.0%
3592296 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.51 43.0 3.62e-01 95.6% 91.7%
3214822 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 41.0 2.75e-01 92.6% 60.0%
4029363 304.20.1.2 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › Nrap_D3 0.51 43.0 3.38e-01 100.0% 76.2%
4544858 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.51 43.0 2.66e-01 98.5% 32.7%
3475963 7.1.1.0 ↗ beta barrels › PDZ domain › PDZ domain › PDZ domain 0.51 38.0 3.36e-01 85.3% 84.5%
3721821 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 34.0 2.30e-01 70.6% 92.9%
4474711 3747.1.1.2 ↗ a+b two layers › Flagellar hook protein FlgE D0 domain › Flagellar hook protein FlgE D0 domain › Flagellar hook protein FlgE D0 domain › Flg_bb_rod,Flg_bbr_C 0.50 34.0 3.01e-01 70.6% 46.7%
D2 high residues 554-670_686-783
PDB
Domain cluster: rep: NC_042352.1__YP_009639584.1__FGG68_gp42__00043__D422-604
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 237.4 4.10e-70 100.0% 48.8%
D3 medium residues 18-75
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kf6B01 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.61 42.0 3.50e-01 72.4% 76.0%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.55 37.0 2.49e-01 70.7% 23.0%
4ii2A04 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 42.0 3.05e-01 98.3% 69.9%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4844112 1058.1.1.1 ↗ extended segments › Herpes DNA polymerase N-terminal domain › Herpes DNA polymerase N-terminal domain › Herpes DNA polymerase N-terminal domain › PF31254 0.70 56.0 5.07e-01 87.9% 70.5%
2732224 1058.1.1.1 ↗ extended segments › Herpes DNA polymerase N-terminal domain › Herpes DNA polymerase N-terminal domain › Herpes DNA polymerase N-terminal domain › PF31254 0.67 53.0 4.85e-01 87.9% 69.6%
3742530 1.1.9.33 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › PUA_NSUN2 0.53 29.0 2.67e-01 86.2% 36.3%
4216608 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.52 38.0 3.50e-01 81.0% 80.0%
D4 medium residues 92-148_245-280
PDB
Domain cluster: rep: DNA_polymerase_catalytic_subunit__NP_944403__Psittacid_alphaherpesvirus_1__50294__D105-157_257-307
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4b08A01 2.40.50.730 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.86 65.0 6.99e-01 100.0% 90.1%
2k75A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.79 61.0 5.90e-01 100.0% 72.8%
1o7iB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.77 62.0 5.76e-01 100.0% 69.3%
4l5tB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.77 57.0 5.76e-01 100.0% 78.0%
8aa9A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.74 64.0 5.91e-01 100.0% 74.6%
2k5vA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.74 58.0 5.70e-01 100.0% 78.6%
1z9fA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.73 58.0 6.01e-01 100.0% 87.6%
2k50A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.73 61.0 5.93e-01 100.0% 80.8%
3u4zA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.72 57.0 5.35e-01 100.0% 69.7%
5gqoA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.72 57.0 5.70e-01 100.0% 80.4%
3f2bA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 57.0 5.70e-01 100.0% 82.3%
4dkaC00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 59.0 6.12e-01 100.0% 94.2%
1gm5A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.71 55.0 5.33e-01 100.0% 74.5%
1fguB01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 61.0 5.88e-01 100.0% 85.7%
3i7fA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 56.0 5.01e-01 100.0% 64.8%
2k5dA01 2.40.50.390 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Conjugative transposon protein, DUF961 0.64 58.0 5.52e-01 100.0% 84.4%
2id0A02 2.40.50.640 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.63 43.0 4.77e-01 100.0% 90.4%
8c5yA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 56.0 4.56e-01 100.0% 80.6%
4xiwC00 3.10.200.10 Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase 0.60 53.0 3.90e-01 95.7% 64.9%
3irbA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 41.0 4.58e-01 98.9% 98.5%
5l37C00 2.40.50.220 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › EutN/Ccml 0.59 46.0 4.74e-01 100.0% 88.4%
1pfsA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 44.0 4.70e-01 100.0% 96.2%
4gnxC03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 52.0 4.14e-01 100.0% 72.7%
3a58A01 2.30.29.90 Mainly Beta › Roll › PH-domain like › 0.55 44.0 3.59e-01 87.1% 70.7%
3mwcA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 42.0 3.70e-01 83.9% 88.9%
2ztnA02 2.40.30.190 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.53 41.0 3.62e-01 83.9% 75.2%
4jmdA00 2.40.400.10 Mainly Beta › Beta Barrel › Acetoacetate decarboxylase-like › Acetoacetate decarboxylase-like 0.52 46.0 3.38e-01 100.0% 71.2%
1vkcA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 41.0 3.52e-01 92.5% 55.4%
2kieA00 2.30.29.110 Mainly Beta › Roll › PH-domain like › 0.51 42.0 3.77e-01 87.1% 88.7%
3rtxA01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.50 42.0 3.54e-01 94.6% 72.1%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5036293 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 64.0 6.27e-01 100.0% 79.0%
168731 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 61.0 6.02e-01 100.0% 76.5%
4955341 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 61.0 5.86e-01 100.0% 71.4%
4964975 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 62.0 6.04e-01 100.0% 77.0%
4958514 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 62.0 6.04e-01 100.0% 77.0%
4985567 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 61.0 6.15e-01 100.0% 81.1%
4934695 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.77 62.0 5.71e-01 100.0% 67.8%
5019817 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.77 60.0 5.67e-01 100.0% 70.0%
3797107 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 57.0 5.69e-01 100.0% 75.8%
4989364 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 57.0 5.66e-01 100.0% 75.8%
4602887 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 54.0 5.95e-01 100.0% 91.9%
4134937 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 68.0 6.52e-01 100.0% 83.8%
5025918 2.1.1.111 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ssb-like_OB 0.75 59.0 5.68e-01 100.0% 73.3%
5001821 2.1.1.111 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ssb-like_OB 0.75 59.0 5.68e-01 100.0% 73.3%
4015435 2.1.1.44 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Dna2 0.75 61.0 6.05e-01 100.0% 83.2%
3666058 2.1.1.44 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Dna2 0.75 61.0 6.11e-01 100.0% 84.2%
5069581 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.74 63.0 5.97e-01 100.0% 76.4%
3256260 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.74 69.0 6.62e-01 100.0% 86.7%
5041944 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.73 62.0 5.91e-01 100.0% 79.0%
3268888 2.1.1.44 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Dna2 0.73 60.0 6.17e-01 100.0% 90.0%
4956351 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 64.0 3.93e-01 100.0% 17.9%
3230021 2.1.1.126 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF272 0.72 50.0 5.34e-01 100.0% 82.5%
4978172 2.1.1.111 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ssb-like_OB 0.72 57.0 5.70e-01 97.8% 82.1%
5036292 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.72 61.0 5.74e-01 100.0% 76.4%
168817 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.72 57.0 5.60e-01 100.0% 79.6%
3357873 2.1.1.315 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › CDC24_OB3, CDC24_OB2, CDC24_OB1 0.71 58.0 3.57e-01 100.0% 16.0%
5081844 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 62.0 5.63e-01 100.0% 71.7%
5016163 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.71 59.0 5.55e-01 100.0% 74.5%
5035149 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 59.0 5.93e-01 100.0% 87.4%
5020459 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 60.0 5.86e-01 100.0% 84.8%
5050058 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.71 61.0 4.87e-01 100.0% 49.1%
5082511 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 59.0 5.70e-01 100.0% 80.0%
4030549 2.1.1.228 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › MCM_bind 0.70 65.0 5.02e-01 100.0% 71.5%
3645341 2.1.1.76 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › REPA_OB_2 0.69 64.0 5.19e-01 100.0% 56.4%
3243395 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.68 45.0 4.96e-01 100.0% 85.3%
4974920 2.1.1.76 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › REPA_OB_2 0.66 54.0 5.34e-01 100.0% 84.0%
3750534 2.1.1.257 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF30832 0.65 60.0 5.23e-01 100.0% 71.9%
5051439 2.1.1.42 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Rep_fac-A_C 0.64 58.0 5.04e-01 100.0% 87.1%
4932742 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 58.0 5.30e-01 100.0% 79.2%
4940588 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.62 56.0 4.98e-01 98.9% 87.2%
3905132 2.1.1.268 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF30833 0.58 53.0 4.15e-01 100.0% 87.2%
3694125 3772.1.1.0 ↗ beta sandwiches › Putative anti-sigma factor BDI_1681 N-terminal domain › Putative anti-sigma factor BDI_1681 N-terminal domain › Putative anti-sigma factor BDI_1681 N-terminal domain 0.53 41.0 3.90e-01 93.5% 71.8%
3365829 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.52 45.0 3.07e-01 94.6% 74.1%
3211061 246.3.1.1 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.51 45.0 3.05e-01 97.8% 91.8%
D5 medium residues 378-468
PDB
Domain cluster: rep: UL30__YP_003084391__Anatid_alphaherpesvirus_1__104388__D444-522
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 79.1 4.70e-22 90.1% 32.2%
D6 medium residues 508-553_671-685
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 28.2 1.20e-06 54.1% 6.8%
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fvmA04 6.10.10.100 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › 0.90 62.0 7.03e-01 72.1% 95.7%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.89 64.0 4.04e-01 75.4% 17.0%
1f5qB02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.61 42.0 3.23e-01 72.1% 75.4%
3bujA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.55 41.0 2.58e-01 85.2% 55.9%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 45.0 3.94e-01 100.0% 86.1%
1nv8B01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.52 38.0 3.64e-01 86.9% 67.6%
2cwoA02 1.10.1200.170 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › RNA silencing suppressor P21, C-terminal domain 0.51 42.0 3.85e-01 93.4% 73.5%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.50 43.0 3.98e-01 96.7% 96.2%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
None — 0.99 72.0 4.24e-01 75.4% 12.6%
3995965 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.98 71.0 4.80e-01 75.4% 24.9%
3797773 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.97 71.0 4.34e-01 75.4% 15.6%
3368695 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.97 70.0 4.13e-01 75.4% 11.8%
1822623 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.96 70.0 4.33e-01 75.4% 16.8%
3628202 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.95 90.0 4.97e-01 100.0% 26.0%
3404726 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.95 67.0 4.15e-01 73.8% 15.3%
3705562 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.94 88.0 4.88e-01 100.0% 31.6%
5025208 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.93 67.0 4.34e-01 75.4% 20.0%
4948574 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.89 81.0 4.79e-01 98.4% 24.0%
5025842 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.80 56.0 4.16e-01 73.8% 30.7%
4931231 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 55.0 3.83e-01 75.4% 23.5%
3983399 5065.1.1.2 ↗ alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD 0.59 41.0 2.68e-01 75.4% 59.7%
3392375 650.1.1.1 ↗ alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ 0.55 44.0 4.27e-01 90.2% 84.3%
D7 medium residues 784-801_814-850
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 30.1 3.30e-07 100.0% 7.5%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2wauA01 1.20.1310.20 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain 0.61 45.0 3.29e-01 80.0% 34.8%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4044734 6076.1.1.1 ↗ alpha arrays › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme › Catalytic cysteine domain in ubiquitin-activating enzyme › UBA_E1_SCCH 0.60 44.0 3.28e-01 80.0% 65.5%
4887238 2484.1.1.2 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.55 35.0 3.07e-01 72.7% 37.2%
D8 medium residues 851-1008
PDB
Domain cluster: rep: DNA_polymerase_catalytic_subunit__NP_073324__Meleagrid_alphaherpesvirus_1__37108__D926-999_1042-1063_1105-1149
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 113.2 2.00e-32 90.5% 27.8%