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BK010646.1__DAC76694.1__X__00016
Bact-VirBK010646.1__DAC76694.1__X__00016
Identity
- Accession:
- BK010646 ↗
- Kingdom:
- phage
Quality
96.3
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 28-50_111-212
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00303.25 best | Thymidylat_synt | 46.0 | 5.20e-12 | 82.4% | 29.4% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bo7A00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.91 | 87.0 | 6.25e-01 | 100.0% | 90.5% |
| 1bkpA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.89 | 84.0 | 6.28e-01 | 100.0% | 85.3% |
| 3v8hC00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.87 | 71.0 | 5.20e-01 | 84.0% | 78.5% |
| 1tisA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.87 | 82.0 | 6.11e-01 | 100.0% | 90.2% |
| 3egyX00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.85 | 79.0 | 6.23e-01 | 96.8% | 86.3% |
| 1b5eA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.84 | 77.0 | 6.02e-01 | 96.0% | 84.2% |
| 3tt2A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.57 | 40.0 | 3.00e-01 | 72.8% | 41.9% |
| 2iexA01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.57 | 40.0 | 3.49e-01 | 72.8% | 72.1% |
| 6p66D01 | 3.40.91.30 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.56 | 31.0 | 3.35e-01 | 71.2% | 61.5% |
| 4zohA02 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.55 | 46.0 | 4.51e-01 | 99.2% | 83.5% |
| 3gkbA00 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.54 | 39.0 | 3.10e-01 | 76.8% | 90.5% |
| 2ozgA02 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 44.0 | 4.07e-01 | 90.4% | 84.8% |
| 6p4wB01 | 3.40.91.30 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.53 | 34.0 | 3.69e-01 | 85.6% | 76.1% |
| 2xswB00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.52 | 44.0 | 3.23e-01 | 90.4% | 62.6% |
| 6u10A00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.51 | 36.0 | 2.78e-01 | 71.2% | 39.4% |
| 4fvaC00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.50 | 42.0 | 3.34e-01 | 88.8% | 62.2% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4225236 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.93 | 90.0 | 6.59e-01 | 100.0% | 86.6% |
| 4937005 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 89.0 | 6.23e-01 | 100.0% | 91.6% |
| 4108234 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 87.0 | 6.20e-01 | 98.4% | 90.0% |
| 4664958 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.92 | 89.0 | 6.66e-01 | 100.0% | 89.4% |
| 4228846 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 89.0 | 6.27e-01 | 100.0% | 91.3% |
| 2540892 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 88.0 | 6.23e-01 | 100.0% | 78.1% |
| 3203076 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 88.0 | 6.23e-01 | 100.0% | 90.0% |
| 4151800 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.92 | 88.0 | 6.35e-01 | 100.0% | 90.5% |
| 3479792 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.92 | 87.0 | 6.22e-01 | 98.4% | 82.3% |
| 5046158 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 78.0 | 6.44e-01 | 88.0% | 83.5% |
| 3944795 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 86.0 | 5.97e-01 | 98.4% | 90.7% |
| 3824671 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 81.0 | 6.03e-01 | 92.8% | 73.2% |
| 4582423 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 81.0 | 6.53e-01 | 92.8% | 84.9% |
| 1900468 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 87.0 | 6.44e-01 | 100.0% | 84.9% |
| 4954631 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.91 | 81.0 | 6.35e-01 | 92.0% | 86.1% |
| 3955287 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.90 | 81.0 | 6.32e-01 | 92.8% | 82.1% |
| 3164619 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.90 | 86.0 | 6.35e-01 | 100.0% | 89.8% |
| 4932636 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.90 | 80.0 | 6.48e-01 | 92.8% | 83.3% |
| 5050802 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.90 | 80.0 | 5.91e-01 | 92.8% | 84.1% |
| 5015648 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.89 | 77.0 | 6.35e-01 | 89.6% | 84.4% |
| 5031349 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.89 | 78.0 | 6.34e-01 | 91.2% | 83.3% |
| 2028021 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.89 | 82.0 | 5.84e-01 | 95.2% | 87.0% |
| 5065331 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.88 | 78.0 | 6.30e-01 | 92.8% | 79.1% |
| 4949404 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.88 | 78.0 | 6.19e-01 | 92.8% | 78.7% |
| 4985883 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.87 | 77.0 | 6.24e-01 | 91.2% | 79.5% |
| 1900473 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.84 | 77.0 | 5.97e-01 | 96.0% | 82.9% |
| 4976145 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.77 | 74.0 | 5.90e-01 | 100.0% | 82.7% |
| 5079331 | 2008.1.1.108 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 | 0.62 | 40.0 | 4.01e-01 | 76.8% | 64.0% |
| 5009937 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.60 | 38.0 | 3.99e-01 | 72.0% | 69.6% |
| 4648357 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 43.0 | 2.49e-01 | 76.0% | 22.5% |
| 4973776 | 2008.1.1.16 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat | 0.56 | 35.0 | 3.34e-01 | 72.0% | 52.7% |
| 5078518 | 2008.1.1.220 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_10 | 0.55 | 36.0 | 3.79e-01 | 72.0% | 73.6% |
| 4943645 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.54 | 38.0 | 3.91e-01 | 88.8% | 75.0% |
| 4946872 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.53 | 39.0 | 3.53e-01 | 75.2% | 63.6% |
| 5041799 | 2008.1.1.220 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_10 | 0.53 | 36.0 | 3.51e-01 | 89.6% | 61.4% |
| 5009448 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.53 | 38.0 | 3.81e-01 | 88.8% | 73.6% |
| 5080539 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.52 | 33.0 | 3.09e-01 | 72.0% | 50.3% |
| 3989293 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.52 | 35.0 | 3.63e-01 | 87.2% | 73.0% |
| 3788721 | 3662.1.1.2 ↗ | a+b two layers › Proteasome assembling chaperone 3 (PAC3)-related › Proteasome assembling chaperone 3 (PAC3)-related › Proteasome assembling chaperone 3 (PAC3)-related › POC3_POC4 | 0.52 | 40.0 | 3.74e-01 | 81.6% | 88.4% |
| 3680604 | 246.3.1.17 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › PF27823 | 0.51 | 38.0 | 2.90e-01 | 80.0% | 33.3% |
| 3642904 | 246.3.1.0 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like | 0.51 | 38.0 | 2.99e-01 | 80.8% | 37.6% |
| 3736568 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.50 | 36.0 | 3.36e-01 | 73.6% | 72.9% |
D2
medium
residues 51-110
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bo7A00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.85 | 76.0 | 4.72e-01 | 100.0% | 39.2% |
| 1bkpA00 | 3.30.572.10 | Alpha Beta › 2-Layer Sandwich › Thymidylate Synthase; Chain A › Thymidylate synthase/dCMP hydroxymethylase domain | 0.83 | 73.0 | 4.68e-01 | 100.0% | 27.3% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.60 | 44.0 | 3.86e-01 | 80.0% | 72.3% |
| 3dkaB01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.54 | 41.0 | 3.31e-01 | 88.3% | 66.7% |
| 1js8A01 | 1.10.1280.10 | Mainly Alpha › Orthogonal Bundle › di-copper center containing domain from catechol oxidase › Di-copper center containing domain from catechol oxidase | 0.52 | 43.0 | 2.88e-01 | 98.3% | 78.3% |
| 2qbyB03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 40.0 | 3.60e-01 | 86.7% | 85.7% |
| 1e7pC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 41.0 | 2.90e-01 | 100.0% | 71.3% |
| 4gtnA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.52 | 35.0 | 3.25e-01 | 70.0% | 70.3% |
| 2ltuA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.50 | 33.0 | 3.28e-01 | 93.3% | 64.5% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4108234 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.85 | 76.0 | 4.73e-01 | 100.0% | 40.0% |
| 4664958 | 266.1.1.0 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase | 0.83 | 73.0 | 4.74e-01 | 100.0% | 27.7% |
| 4225236 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.82 | 73.0 | 4.65e-01 | 100.0% | 29.3% |
| 4934293 | 4993.1.1.0 ↗ | extended segments › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit › Glu-tRNAGln amidotransferase C subunit | 0.56 | 45.0 | 4.25e-01 | 96.7% | 85.0% |
| 3993627 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 39.0 | 3.78e-01 | 80.0% | 81.4% |
| 5045348 | 604.34.1.0 ↗ | alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase | 0.53 | 34.0 | 3.15e-01 | 90.0% | 47.1% |
| 2479 | 101.1.1.47 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Mu_2 | 0.52 | 40.0 | 3.80e-01 | 86.7% | 82.7% |
| 3253839 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 39.0 | 3.32e-01 | 90.0% | 90.8% |