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BML_08012017_9_75m_scaffold_2_prodigal-single.1__X__X__00008

Bact-Vir

BML_08012017_9_75m_scaffold_2_prodigal-single.1__X__X__00008

Identity

Kingdom:
phage

Quality

68.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 598-723
PDB
D2 high residues 961-1070
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4xxiA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.88 73.0 6.48e-01 92.7% 64.6%
1cpcB00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.87 77.0 6.46e-01 92.7% 64.5%
1b8dA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.81 71.0 6.09e-01 92.7% 67.1%
1a87A02 1.10.490.30 Mainly Alpha › Orthogonal Bundle › Globin-like › Colicin 0.79 61.0 4.97e-01 92.7% 45.0%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.72 60.0 5.66e-01 94.5% 74.6%
3b9wA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.65 55.0 3.86e-01 92.7% 83.1%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 54.0 5.05e-01 92.7% 76.3%
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 56.0 4.33e-01 100.0% 96.8%
6k6iA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 56.0 4.50e-01 100.0% 72.1%
4okmD00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.62 48.0 3.52e-01 83.6% 68.2%
3s4lA00 1.10.3210.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › 0.61 48.0 4.04e-01 84.5% 98.0%
4f4cA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.61 52.0 3.16e-01 93.6% 46.0%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.60 44.0 3.66e-01 75.5% 91.5%
1cqxA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 50.0 4.59e-01 92.7% 71.3%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.60 43.0 3.55e-01 74.5% 71.2%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.58 41.0 3.80e-01 73.6% 76.7%
1t6jA03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.58 45.0 4.70e-01 84.5% 91.3%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 32.0 3.63e-01 91.8% 72.5%
2aw6A02 1.25.40.400 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 41.0 3.31e-01 84.5% 37.6%
6humG01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.57 38.0 3.40e-01 72.7% 46.9%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 40.0 3.22e-01 71.8% 81.9%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.57 40.0 3.44e-01 73.6% 92.2%
5j6bD01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.57 49.0 3.58e-01 92.7% 49.1%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 41.0 3.20e-01 76.4% 74.8%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.56 41.0 3.81e-01 76.4% 77.5%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.56 47.0 3.46e-01 91.8% 46.2%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 35.0 3.56e-01 82.7% 62.2%
3rosA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.56 49.0 3.66e-01 96.4% 52.6%
3vz3A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 48.0 3.66e-01 95.5% 53.2%
6fjxA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 45.0 3.46e-01 90.0% 50.6%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 48.0 3.61e-01 95.5% 52.6%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.55 42.0 4.10e-01 86.4% 73.2%
3ee4A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.55 45.0 3.42e-01 92.7% 67.5%
1yuzB01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 38.0 3.61e-01 72.7% 100.0%
3nc3B00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.54 47.0 3.31e-01 99.1% 89.1%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 42.0 4.08e-01 91.8% 75.6%
2c0gA02 1.20.1150.12 Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain 0.53 40.0 4.10e-01 86.4% 82.1%
2j6lA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.53 47.0 3.44e-01 98.2% 49.3%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.52 38.0 3.40e-01 75.5% 67.3%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 36.0 3.60e-01 71.8% 90.6%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.52 40.0 3.29e-01 84.5% 75.5%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 36.0 3.45e-01 72.7% 76.6%
3rh9A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 42.0 3.16e-01 92.7% 46.4%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3564576 106.1.1.8 alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like 0.82 67.0 6.01e-01 93.6% 64.0%
3279122 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.81 67.0 6.72e-01 87.3% 89.1%
3407641 106.1.1.8 alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like 0.80 66.0 5.81e-01 93.6% 61.9%
3236920 106.1.1.8 alpha arrays › Globin-like › Globin-like › Globin-like › HisK-N-like 0.79 66.0 5.89e-01 93.6% 64.7%
3280184 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.79 67.0 6.02e-01 93.6% 67.3%
3284117 106.1.1.11 alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.74 62.0 5.78e-01 90.0% 75.6%
4029967 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.66 54.0 5.32e-01 92.7% 83.5%
5039816 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.64 43.0 4.62e-01 85.5% 80.0%
5074854 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.62 43.0 3.46e-01 70.9% 79.5%
3445971 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 46.0 3.94e-01 88.2% 68.9%
5042372 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.57 38.0 3.92e-01 90.0% 71.2%
3894393 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.57 46.0 4.27e-01 90.9% 77.3%
5000027 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.57 45.0 3.39e-01 86.4% 51.5%
5026366 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.57 39.0 3.41e-01 70.9% 74.4%
5012580 101.1.10.76 alpha arrays › HTH › HTH › Cyclin-like › HTH_23 0.57 49.0 4.91e-01 96.4% 92.2%
3528006 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.56 39.0 2.88e-01 90.9% 25.1%
5032053 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.55 38.0 3.67e-01 71.8% 81.5%
3408518 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.55 44.0 4.27e-01 88.2% 82.4%
4263052 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.54 48.0 3.80e-01 96.4% 90.2%
3856843 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.54 40.0 2.90e-01 78.2% 88.1%
4277877 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.53 39.0 3.37e-01 77.3% 78.9%
3935538 3286.1.1.1 alpha complex topology › Glypican insertion domain › Glypican insertion domain › Glypican insertion domain › Glypican 0.53 45.0 3.50e-01 95.5% 81.5%
3745013 101.1.10.12 alpha arrays › HTH › HTH › Cyclin-like › Spy1 0.53 40.0 3.74e-01 87.3% 63.6%
3188247 7524.1.1.1 a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh 0.53 46.0 3.03e-01 97.3% 31.5%
3612806 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.52 42.0 3.85e-01 88.2% 85.3%
3933660 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.52 40.0 3.51e-01 80.9% 70.9%
3493397 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.52 41.0 3.51e-01 86.4% 83.7%
4367801 601.1.1.140 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Apolipoprotein 0.52 39.0 4.06e-01 80.9% 94.3%
3720250 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.52 41.0 3.81e-01 87.3% 84.6%
4991318 150.2.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Cobalamin adenosyltransferase › Cobalamin adenosyltransferase › Cob_adeno_trans 0.52 46.0 4.10e-01 100.0% 81.9%
3485131 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.51 39.0 2.77e-01 92.7% 25.1%
5062170 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.50 38.0 3.76e-01 90.0% 75.8%
4026893 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.50 35.0 2.88e-01 71.8% 90.7%
D3 high residues 2308-2385
PDB
D4 medium residues 26-104_138-154
PDB
D5 medium residues 105-137_155-194
PDB
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vsvA01 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.81 75.0 4.44e-01 100.0% 19.2%
6kqsA01 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.80 73.0 4.45e-01 100.0% 24.6%
4oj5C04 2.160.20.130 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › 0.78 70.0 5.16e-01 100.0% 51.4%
4zyaB00 3.30.1910.20 Alpha Beta › 2-Layer Sandwich › so0334 like fold › asparaginyl-tRNA synthetase, N-terminal domain 0.74 51.0 5.06e-01 71.2% 88.2%
5gkdA02 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.69 63.0 4.14e-01 100.0% 29.5%
1h80B00 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.66 61.0 3.68e-01 100.0% 17.9%
2fx5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 49.0 3.44e-01 94.5% 53.1%
1k8fA00 2.160.20.70 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › 0.57 45.0 3.54e-01 86.3% 66.2%
2pygA00 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.57 45.0 2.95e-01 91.8% 40.4%
4l0cA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 48.0 3.39e-01 98.6% 66.5%
1r1dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 44.0 3.17e-01 90.4% 55.0%
4h0nA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 45.0 3.37e-01 94.5% 64.0%
1wkvA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 41.0 3.07e-01 84.9% 56.1%
2ahuA01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.53 43.0 3.02e-01 93.2% 43.6%
2bkaA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 42.0 3.10e-01 91.8% 89.6%
1xr4B01 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.52 42.0 3.01e-01 98.6% 28.4%
5gkqB01 2.160.20.10 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › Single-stranded right-handed beta-helix, Pectin lyase-like 0.52 43.0 2.81e-01 100.0% 41.6%
1r0sA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 42.0 3.54e-01 91.8% 68.2%
1im5A00 3.40.50.850 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like 0.51 38.0 3.01e-01 83.6% 98.3%
1k6dB00 3.40.1080.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase 0.51 40.0 2.97e-01 90.4% 90.4%
2x5oA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 37.0 3.50e-01 79.5% 92.4%
2pk3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 41.0 3.05e-01 94.5% 74.9%
5bxrA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.51 40.0 2.72e-01 93.2% 38.8%
4qjiB00 3.40.50.10300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like 0.50 38.0 2.89e-01 87.7% 80.1%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4970380 207.2.1.13 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › NosD 0.90 86.0 5.38e-01 100.0% 23.4%
4969480 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.90 86.0 5.50e-01 100.0% 26.3%
4969266 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.88 81.0 4.43e-01 100.0% 7.3%
3272834 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.88 83.0 4.71e-01 100.0% 12.3%
4969980 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.88 81.0 4.56e-01 100.0% 10.7%
4969790 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.88 81.0 4.63e-01 100.0% 12.2%
5032868 207.2.1.13 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › NosD 0.86 80.0 5.59e-01 100.0% 35.1%
4980561 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.86 80.0 4.95e-01 100.0% 21.1%
4981818 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.86 72.0 4.62e-01 100.0% 21.3%
5034990 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.86 78.0 4.75e-01 100.0% 18.4%
5034599 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.85 79.0 4.87e-01 100.0% 19.5%
4969946 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.85 76.0 4.58e-01 100.0% 16.6%
4981149 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.85 79.0 5.42e-01 98.6% 42.3%
4981379 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.85 72.0 4.89e-01 100.0% 28.9%
4981080 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.85 71.0 4.76e-01 100.0% 26.0%
5081288 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.84 71.0 4.35e-01 100.0% 17.1%
1841000 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.84 75.0 7.45e-01 94.5% 98.7%
5032796 207.2.1.13 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › NosD 0.84 69.0 4.58e-01 100.0% 24.7%
4969572 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.83 77.0 4.72e-01 100.0% 18.5%
4982332 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.82 76.0 4.99e-01 100.0% 32.7%
2831960 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.81 74.0 4.32e-01 100.0% 18.4%
4211588 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.80 74.0 4.42e-01 100.0% 20.4%
1285029 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.79 71.0 4.09e-01 100.0% 12.0%
2831959 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.79 72.0 4.16e-01 100.0% 18.4%
3250810 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.78 71.0 4.81e-01 100.0% 40.7%
4466879 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.77 71.0 4.37e-01 100.0% 22.8%
4980525 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.75 70.0 4.31e-01 100.0% 22.6%
5033180 207.2.1.22 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Beta_helix 0.74 69.0 4.52e-01 98.6% 32.1%
2036144 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.69 64.0 4.14e-01 100.0% 29.2%
4012052 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.67 62.0 3.88e-01 100.0% 22.9%
1954234 207.2.1.31 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Gp49_Pectate_lyase_like 0.65 57.0 5.18e-01 100.0% 72.9%
3586852 207.2.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Glyco_hydro_28 0.65 59.0 3.59e-01 100.0% 34.0%
3939653 1089.1.1.1 a+b two layers › Asparaginal-tRNA synthetase N-terminal domain › Asparaginal-tRNA synthetase N-terminal domain › Asparaginal-tRNA synthetase N-terminal domain › AsnRS_N 0.64 50.0 5.03e-01 93.2% 80.0%
3761168 1089.1.1.1 a+b two layers › Asparaginal-tRNA synthetase N-terminal domain › Asparaginal-tRNA synthetase N-terminal domain › Asparaginal-tRNA synthetase N-terminal domain › AsnRS_N 0.63 50.0 4.46e-01 94.5% 61.0%
3988981 2484.1.1.66 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.57 45.0 3.45e-01 89.0% 48.3%
4338633 7516.1.1.17 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_6 0.57 43.0 2.93e-01 89.0% 22.0%
3386982 2004.1.1.343 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 0.56 43.0 3.69e-01 93.2% 50.8%
4995410 207.8.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Stabilizer of iron transporter sufD › Stabilizer of iron transporter sufD › SUFBD 0.56 46.0 3.06e-01 93.2% 94.5%
4602564 7579.1.1.13 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › DLH 0.55 48.0 3.37e-01 100.0% 50.6%
4292213 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.55 44.0 3.20e-01 91.8% 93.9%
3633790 207.2.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like 0.55 41.0 2.70e-01 83.6% 35.1%
5078382 207.8.1.1 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Stabilizer of iron transporter sufD › Stabilizer of iron transporter sufD › SUFBD 0.54 42.0 2.87e-01 89.0% 72.5%
None 0.53 44.0 2.79e-01 94.5% 21.0%
3409312 2003.1.7.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › CoA_trans 0.52 41.0 2.88e-01 94.5% 25.6%
3935011 7512.1.1.1 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.50 43.0 3.03e-01 100.0% 80.4%
D6 medium residues 195-351
PDB
D7 medium residues 484-501_526-593
PDB
D8 medium residues 756-848
PDB
D9 medium residues 849-960
PDB
D10 medium residues 1300-1412_1424-1450
PDB
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.78 32.0 3.64e-01 99.3% 51.4%
4zvaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.72 57.0 5.61e-01 82.1% 81.9%
2r40D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.64 48.0 4.02e-01 77.9% 62.7%
1p8dB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.64 48.0 4.05e-01 79.3% 61.9%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 30.0 3.97e-01 81.4% 89.2%
4jz6A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 45.0 3.79e-01 90.0% 74.3%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.55 44.0 4.64e-01 95.7% 96.0%
3pqaB01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 45.0 3.64e-01 88.6% 66.5%
5ekcF01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 45.0 3.59e-01 90.0% 64.2%
7dswA01 1.20.1530.20 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › 0.54 46.0 3.39e-01 93.6% 75.8%
1o9jC01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.54 45.0 3.59e-01 92.1% 62.8%
8h72B01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 39.0 3.08e-01 75.7% 85.5%
6fjxA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.54 45.0 3.67e-01 91.4% 69.0%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.53 44.0 3.53e-01 90.0% 65.7%
7w5gA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.53 47.0 3.55e-01 99.3% 90.9%
1jfaB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 46.0 3.44e-01 95.7% 86.0%
1euhA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 44.0 3.56e-01 92.1% 69.7%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 34.0 3.67e-01 84.3% 76.9%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 46.0 3.64e-01 97.1% 99.7%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.52 47.0 3.49e-01 98.6% 75.4%
1sj7C00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 39.0 3.76e-01 95.7% 69.3%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 38.0 3.92e-01 77.1% 100.0%
1t90A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.51 43.0 3.49e-01 93.6% 66.8%
2gbbB00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.51 39.0 3.76e-01 79.3% 93.5%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.50 32.0 3.64e-01 87.1% 86.4%
7xk2R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.50 36.0 2.99e-01 74.3% 95.5%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4945009 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.61 44.0 4.03e-01 74.3% 93.3%
3628947 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.61 49.0 3.55e-01 87.1% 75.3%
3719894 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.58 42.0 3.86e-01 73.6% 85.0%
4412026 2498.1.1.46 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Aspzincin_M35 0.58 43.0 4.04e-01 77.9% 97.7%
4945008 5079.1.1.0 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain 0.57 43.0 3.68e-01 79.3% 76.0%
5037963 1079.1.1.0 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.57 39.0 3.25e-01 70.0% 90.6%
3744215 627.1.1.1 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 0.55 40.0 4.00e-01 76.4% 100.0%
3689936 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.54 48.0 3.40e-01 99.3% 86.9%
3245682 601.1.3.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_middle 0.53 40.0 3.85e-01 95.7% 68.8%
4935224 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.52 45.0 3.27e-01 94.3% 57.4%
5041287 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.51 38.0 3.14e-01 75.7% 74.2%
3405394 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 47.0 3.23e-01 99.3% 83.1%
5053545 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.51 39.0 3.35e-01 79.3% 78.2%
3285567 5069.1.1.17 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF6529 0.51 39.0 3.62e-01 79.3% 86.8%
3179886 1079.1.1.12 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › GDT1 0.51 37.0 3.46e-01 75.7% 92.6%
4997271 1188.1.1.1 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip 0.50 41.0 3.47e-01 89.3% 97.6%
5041443 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.50 45.0 3.54e-01 97.1% 69.3%
D11 medium residues 1576-1679
PDB
D12 medium residues 1680-1730_1747-1805
PDB
D13 medium residues 1962-2018
PDB
Domain cluster: representative
CATH (59)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l8kA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.75 66.0 4.36e-01 96.5% 41.5%
2mpnA00 6.10.140.1340 Special › Helix non-globular › Helix Hairpins › 0.72 59.0 5.62e-01 100.0% 77.9%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.71 59.0 5.04e-01 91.2% 60.4%
2aj6A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.71 55.0 4.38e-01 87.7% 40.8%
2aswA00 1.10.8.500 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › HAMP domain in histidine kinase 0.69 40.0 4.03e-01 82.5% 58.9%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 58.0 5.30e-01 100.0% 73.1%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 55.0 5.59e-01 89.5% 91.1%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 49.0 4.13e-01 78.9% 45.8%
4ex8A00 3.40.1790.10 Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain 0.67 48.0 3.02e-01 78.9% 14.3%
2bnlC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.67 53.0 4.22e-01 94.7% 41.8%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 59.0 5.83e-01 100.0% 93.4%
1ks9A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.66 53.0 4.19e-01 96.5% 42.3%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.65 57.0 5.44e-01 100.0% 83.8%
2v40A02 1.10.300.10 Mainly Alpha › Orthogonal Bundle › Adenylosuccinate Synthetase, subunit A; domain 2 › Adenylosuccinate Synthetase, subunit A, domain 2 0.65 49.0 4.36e-01 86.0% 55.7%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.64 42.0 3.79e-01 100.0% 45.9%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.64 47.0 4.56e-01 89.5% 70.1%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.63 54.0 4.60e-01 100.0% 58.2%
3keyA01 1.10.10.1080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain 0.63 50.0 4.36e-01 87.7% 79.3%
3umgA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.62 47.0 4.46e-01 89.5% 69.0%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.62 42.0 3.46e-01 70.2% 43.7%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 52.0 3.75e-01 98.2% 97.1%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.62 49.0 5.12e-01 96.5% 100.0%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.62 46.0 3.89e-01 96.5% 47.0%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 53.0 4.92e-01 100.0% 75.7%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.61 55.0 4.43e-01 100.0% 62.7%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 53.0 4.76e-01 94.7% 100.0%
3iylB02 1.10.2050.10 Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 0.61 49.0 3.86e-01 94.7% 45.5%
1x0tA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.61 47.0 4.66e-01 87.7% 86.9%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 49.0 4.08e-01 100.0% 51.9%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 51.0 4.23e-01 100.0% 53.8%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.58 50.0 3.80e-01 100.0% 44.1%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.58 50.0 4.83e-01 100.0% 91.0%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.58 45.0 3.43e-01 91.2% 86.9%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 48.0 4.36e-01 100.0% 67.1%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 50.0 4.88e-01 100.0% 90.3%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.57 49.0 4.39e-01 100.0% 67.9%
4lunU00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 45.0 2.76e-01 87.7% 15.4%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.57 50.0 4.30e-01 98.2% 70.0%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 47.0 4.17e-01 94.7% 63.2%
1oj7A02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.57 49.0 3.38e-01 100.0% 73.5%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.57 48.0 3.58e-01 100.0% 77.6%
1gcbA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 46.0 2.85e-01 100.0% 14.0%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.56 49.0 3.81e-01 100.0% 52.7%
6ygiB01 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.56 50.0 3.70e-01 100.0% 54.1%
4gpkB01 1.25.40.1000 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 38.0 3.22e-01 71.9% 70.7%
1ailA00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.56 44.0 4.14e-01 100.0% 71.4%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.55 47.0 4.20e-01 96.5% 76.8%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.55 46.0 4.05e-01 100.0% 62.6%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 45.0 3.96e-01 100.0% 75.0%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.55 47.0 4.32e-01 100.0% 85.5%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.54 44.0 4.40e-01 100.0% 90.3%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.54 43.0 4.26e-01 96.5% 93.8%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.53 46.0 4.06e-01 100.0% 69.0%
1vryA00 6.10.250.2810 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.53 39.0 3.91e-01 94.7% 77.0%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 43.0 3.73e-01 100.0% 57.4%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.52 36.0 3.15e-01 100.0% 43.1%
3bulA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.51 41.0 3.66e-01 94.7% 59.8%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 3.88e-01 100.0% 76.3%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 3.56e-01 100.0% 70.6%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5044842 212.1.1.22 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans 0.82 71.0 4.71e-01 100.0% 25.0%
3436965 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.76 61.0 5.21e-01 89.5% 75.8%
3613737 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.76 55.0 3.51e-01 78.9% 99.3%
3792061 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.76 66.0 5.46e-01 100.0% 59.2%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.74 63.0 5.52e-01 100.0% 63.5%
3617842 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.74 63.0 5.73e-01 98.2% 75.0%
4149728 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.73 64.0 5.75e-01 100.0% 70.0%
3401272 174.1.1.29 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 0.73 62.0 4.45e-01 98.2% 32.4%
3739839 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.71 61.0 5.01e-01 100.0% 52.7%
3261428 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.71 53.0 4.07e-01 100.0% 35.4%
3389329 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.71 62.0 3.86e-01 100.0% 17.8%
5028558 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.71 60.0 5.06e-01 100.0% 56.0%
4939889 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.69 59.0 4.73e-01 100.0% 50.8%
3290367 3470.1.1.0 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain 0.68 54.0 5.19e-01 100.0% 75.4%
2832675 2006.1.4.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5 0.67 58.0 4.01e-01 100.0% 29.8%
4109908 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.67 55.0 4.81e-01 100.0% 61.2%
4477848 3068.2.1.1 a+b complex topology › Flagellar protein FlgA N-terminal domain-like › RNase J C-terminal domain › RNase J C-terminal domain › RNase_J_C 0.67 58.0 4.75e-01 100.0% 51.8%
5004790 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.66 58.0 5.03e-01 100.0% 63.3%
3591291 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.66 56.0 3.93e-01 100.0% 29.6%
3589830 5043.2.1.8 extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 0.66 56.0 5.31e-01 98.2% 87.1%
4180835 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.66 58.0 5.46e-01 100.0% 81.4%
3999314 5058.1.1.35 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › EMC6 0.66 55.0 5.10e-01 100.0% 74.7%
3347379 3470.1.1.26 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › DUF543 0.66 58.0 5.59e-01 100.0% 87.7%
3988424 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.65 57.0 5.51e-01 100.0% 90.8%
5058593 161.1.1.1 alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › SecA_SW 0.65 54.0 4.23e-01 100.0% 40.7%
4946345 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.65 55.0 4.24e-01 100.0% 94.3%
3638123 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.65 56.0 4.41e-01 100.0% 48.0%
2799599 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.65 58.0 5.02e-01 100.0% 68.6%
4630202 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.64 57.0 4.91e-01 100.0% 66.3%
3715371 1076.1.1.1 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like 0.64 53.0 3.49e-01 98.2% 28.7%
3669572 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.64 49.0 4.62e-01 89.5% 68.0%
3641330 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.64 55.0 3.93e-01 100.0% 42.8%
3570117 375.6.1.2 few secondary structure elements › Rubredoxin-like › FlhC-like › FlhC-like › PF31275 0.63 53.0 5.29e-01 98.2% 98.3%
4107823 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 55.0 4.58e-01 100.0% 59.0%
4554416 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.62 50.0 4.46e-01 100.0% 62.2%
4365052 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 53.0 4.57e-01 100.0% 62.1%
3913300 3755.3.1.303 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th 0.61 51.0 3.89e-01 100.0% 39.3%
4014515 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 46.0 4.07e-01 89.5% 54.7%
4370184 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.60 50.0 3.64e-01 100.0% 69.0%
4024385 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.60 51.0 3.93e-01 100.0% 40.7%
3624567 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 48.0 3.58e-01 96.5% 71.2%
5044800 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.60 53.0 4.73e-01 100.0% 77.5%
3676117 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 49.0 3.26e-01 98.2% 25.7%
4933898 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.59 51.0 4.65e-01 100.0% 75.6%
1206502 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.59 49.0 4.08e-01 100.0% 51.9%
4142346 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.59 53.0 4.21e-01 100.0% 53.6%
4267024 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.59 53.0 4.82e-01 100.0% 89.3%
4998530 2498.1.1.10 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.58 51.0 3.25e-01 98.2% 20.8%
3335568 160.1.1.1 alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › ATP-synt_ab_C 0.58 48.0 3.99e-01 89.5% 54.0%
4961508 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.58 48.0 4.53e-01 100.0% 94.7%
3946910 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.58 50.0 3.54e-01 100.0% 45.4%
2732157 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.58 50.0 4.73e-01 100.0% 87.0%
3262256 610.1.1.1 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 0.58 40.0 3.48e-01 73.7% 46.3%
3962893 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.57 46.0 4.07e-01 100.0% 62.1%
4939264 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.56 47.0 4.45e-01 98.2% 100.0%
5044551 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.55 47.0 4.53e-01 100.0% 87.7%
3730806 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.54 46.0 3.59e-01 96.5% 70.4%
D14 medium residues 2204-2295
PDB