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BML_08042016_6_5m_scaffold_14_prodigal-single.1__X__X__00010

Bact-Vir

BML_08042016_6_5m_scaffold_14_prodigal-single.1__X__X__00010

Identity

Kingdom:
phage

Quality

90.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 104-164_392-447
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01970.22 best TctA 53.9 1.70e-14 75.2% 16.6%
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 31.0 3.62e-01 75.2% 57.3%
1oahA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 34.0 3.15e-01 77.8% 39.4%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 40.0 3.76e-01 94.0% 47.9%
1rxqD00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.60 36.0 3.18e-01 100.0% 40.2%
1ygmA01 1.10.220.90 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Mistic 0.58 36.0 4.03e-01 95.7% 80.0%
8ex5A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.58 51.0 4.36e-01 97.4% 75.9%
7wz5A01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.58 36.0 3.39e-01 100.0% 48.3%
4uvmA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.57 50.0 3.33e-01 100.0% 60.8%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 49.0 4.10e-01 95.7% 75.9%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 49.0 3.89e-01 97.4% 67.9%
3nf2A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 40.0 2.87e-01 100.0% 25.4%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 50.0 3.69e-01 100.0% 93.4%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.55 49.0 4.21e-01 100.0% 82.9%
4iu9A00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 48.0 3.36e-01 100.0% 56.8%
1pduA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.53 39.0 3.14e-01 76.9% 46.1%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 31.0 2.79e-01 78.6% 39.6%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.52 42.0 3.35e-01 88.9% 80.5%
4q2cA01 1.10.3210.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › 0.51 40.0 3.15e-01 84.6% 84.8%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.51 29.0 3.19e-01 100.0% 68.1%
3ipiA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 41.0 3.31e-01 93.2% 78.4%
5zjgA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.51 30.0 3.07e-01 87.2% 58.0%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4944200 5059.1.1.67 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › AsnC_trans_reg 0.68 62.0 4.40e-01 99.1% 46.9%
4983940 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.63 55.0 5.26e-01 94.0% 81.5%
3449147 5050.1.1.11 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 0.63 55.0 4.64e-01 94.9% 74.4%
4272227 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.62 55.0 4.06e-01 97.4% 88.7%
3386452 5050.1.1.21 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FTR1 0.61 56.0 5.20e-01 100.0% 89.7%
4386512 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.61 55.0 4.06e-01 100.0% 87.5%
3764343 5050.1.1.4 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran 0.61 56.0 4.56e-01 100.0% 79.0%
4972685 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 54.0 4.36e-01 100.0% 98.2%
3870499 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.60 53.0 4.09e-01 97.4% 69.6%
3701311 5059.1.1.17 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TMEM234 0.59 44.0 4.51e-01 97.4% 79.1%
3693483 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.59 52.0 4.14e-01 97.4% 65.7%
4018516 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 52.0 4.30e-01 96.6% 78.1%
4946068 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.59 52.0 4.18e-01 97.4% 70.4%
3645542 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.59 31.0 2.94e-01 70.1% 44.4%
4967576 5059.1.1.0 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter 0.59 41.0 3.86e-01 72.6% 81.4%
3568034 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.58 51.0 3.38e-01 100.0% 56.4%
3670143 5050.1.1.2 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 0.58 49.0 3.60e-01 94.9% 52.6%
4026607 5050.1.1.28 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.58 52.0 4.16e-01 100.0% 66.0%
3269680 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.58 49.0 3.77e-01 94.0% 64.1%
3674957 5050.1.1.28 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.58 50.0 4.11e-01 96.6% 75.5%
5044770 5050.1.1.14 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 0.57 49.0 4.01e-01 94.0% 74.1%
3352210 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.57 42.0 3.45e-01 77.8% 95.6%
5052891 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 49.0 4.10e-01 97.4% 75.8%
5074854 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.57 48.0 3.99e-01 94.0% 71.2%
5019253 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 33.0 2.26e-01 76.1% 18.4%
3573844 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.56 50.0 4.01e-01 100.0% 75.0%
5001604 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 49.0 4.12e-01 96.6% 73.0%
3176050 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 50.0 3.97e-01 100.0% 72.7%
3839166 603.5.1.0 alpha bundles › STAT-like › FlgN-like › FlgN-like 0.56 45.0 4.49e-01 100.0% 83.3%
5082506 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 47.0 3.97e-01 94.0% 77.6%
5070376 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 48.0 4.04e-01 96.6% 76.1%
3408498 5050.1.1.22 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like 0.55 46.0 3.91e-01 93.2% 74.6%
4340320 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.55 34.0 3.33e-01 75.2% 56.0%
3336590 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.54 47.0 3.77e-01 97.4% 67.8%
3967590 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 46.0 3.74e-01 94.0% 71.5%
4413986 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 3.64e-01 97.4% 62.8%
3182235 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 46.0 3.63e-01 94.0% 62.0%
3496960 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 33.0 2.38e-01 100.0% 20.9%
3733145 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 39.0 3.67e-01 76.1% 89.3%
3915982 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 40.0 3.97e-01 100.0% 75.2%
3988301 5050.1.1.60 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 0.52 46.0 3.88e-01 100.0% 75.1%
3216798 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.52 37.0 3.26e-01 100.0% 51.5%
3178655 174.1.1.21 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2417 0.52 38.0 3.41e-01 77.8% 84.1%
4327137 1002.1.1.1 alpha complex topology › Fluoride ion channel › Fluoride ion channel › Fluoride ion channel › CRCB 0.51 40.0 4.02e-01 100.0% 79.7%
4033252 7014.1.1.2 alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › TauE 0.51 43.0 3.45e-01 94.0% 95.1%
3563679 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 36.0 3.80e-01 100.0% 81.0%
4998773 3755.3.1.305 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook 0.50 35.0 2.93e-01 75.2% 43.6%
D2 medium residues 1-101_166-200_287-346
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01970.22 best TctA 116.9 1.30e-33 53.1% 23.6%
PF01970.22 TctA 54.2 1.30e-14 34.2% 14.0%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 29.0 3.97e-01 82.7% 78.6%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.62 34.0 3.68e-01 88.8% 60.6%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.61 37.0 3.69e-01 90.3% 56.5%
1f7uA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 30.0 3.75e-01 88.8% 73.6%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.59 28.0 3.82e-01 76.5% 87.8%
3edvA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 30.0 3.11e-01 84.7% 50.3%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.56 33.0 3.25e-01 83.7% 51.4%
3wvoC02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.56 32.0 3.85e-01 93.9% 83.8%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.55 38.0 4.01e-01 97.4% 77.6%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.55 41.0 4.11e-01 76.0% 95.5%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.53 30.0 3.59e-01 98.0% 80.9%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.52 40.0 4.24e-01 100.0% 92.4%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 28.0 2.94e-01 81.6% 55.4%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5070186 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.60 39.0 4.04e-01 92.3% 69.4%
4991909 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.59 38.0 3.99e-01 91.3% 70.3%
5083115 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.59 38.0 3.98e-01 90.3% 69.2%
4953930 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.58 42.0 4.10e-01 99.5% 65.9%
3921501 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.55 41.0 3.95e-01 76.0% 92.7%
5006033 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.54 34.0 3.46e-01 90.3% 62.0%
3700079 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.53 39.0 3.79e-01 75.5% 93.8%
4026662 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.53 28.0 3.29e-01 82.7% 70.7%
3631038 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 39.0 3.82e-01 77.0% 98.1%
3341663 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 39.0 3.74e-01 76.5% 90.0%
D3 medium residues 201-286
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01970.22 best TctA 87.8 8.70e-25 100.0% 19.4%
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fbzA01 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 53.0 5.06e-01 83.7% 71.6%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.68 56.0 4.95e-01 89.5% 87.2%
5d0yA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.68 53.0 4.30e-01 90.7% 45.2%
3vw4A01 1.10.340.50 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › 0.68 56.0 5.49e-01 93.0% 84.8%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.66 53.0 5.51e-01 87.2% 100.0%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 42.0 3.57e-01 72.1% 42.2%
7dl9A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 51.0 3.93e-01 88.4% 79.9%
2wy4A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 51.0 4.43e-01 91.9% 100.0%
3pmcA00 1.10.490.70 Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain 0.62 48.0 4.18e-01 82.6% 61.4%
6wk3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.62 53.0 4.48e-01 95.3% 95.9%
4iu9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 53.0 4.09e-01 96.5% 90.6%
2oifB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 50.0 4.18e-01 89.5% 98.7%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.61 46.0 4.33e-01 82.6% 69.1%
1binA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 49.0 4.17e-01 88.4% 97.9%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 52.0 4.29e-01 94.2% 96.8%
1sedA00 1.10.3750.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein YhaI fold › YhaI-like 0.60 44.0 4.09e-01 79.1% 68.8%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 41.0 3.69e-01 72.1% 51.7%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 49.0 4.61e-01 93.0% 99.1%
3owaA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 45.0 3.87e-01 82.6% 59.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 46.0 4.34e-01 87.2% 89.7%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.58 43.0 4.20e-01 88.4% 69.7%
1jwnA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 44.0 3.78e-01 82.6% 93.8%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 46.0 4.49e-01 86.0% 99.0%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 45.0 3.92e-01 87.2% 98.6%
2w2dD01 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.57 49.0 3.27e-01 100.0% 72.2%
4b4yA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 46.0 3.84e-01 87.2% 97.3%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 43.0 3.88e-01 82.6% 64.5%
1a22A00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 49.0 3.91e-01 97.7% 77.8%
2bk9A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 48.0 4.04e-01 100.0% 100.0%
3lszA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 42.0 3.74e-01 82.6% 70.4%
3on2A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 47.0 3.76e-01 100.0% 46.8%
4fm3A00 1.20.1270.390 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 37.0 3.64e-01 73.3% 64.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 44.0 4.15e-01 91.9% 91.5%
3bruB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 45.0 3.64e-01 100.0% 50.3%
3fmsA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.53 42.0 3.68e-01 89.5% 78.7%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 38.0 3.56e-01 75.6% 81.3%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 43.0 3.99e-01 89.5% 85.3%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 41.0 4.02e-01 83.7% 84.6%
1wvtA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.52 44.0 3.69e-01 93.0% 62.8%
4p9fA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 42.0 3.60e-01 89.5% 82.6%
3sl9B00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 36.0 2.99e-01 96.5% 38.8%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 45.0 3.59e-01 98.8% 74.9%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 42.0 3.68e-01 91.9% 76.5%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.51 39.0 3.26e-01 80.2% 74.1%
3zheC01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 37.0 3.05e-01 97.7% 37.5%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.51 39.0 3.34e-01 83.7% 57.5%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.51 42.0 3.36e-01 94.2% 93.7%
3lomA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.00e-01 95.3% 38.9%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 43.0 3.63e-01 100.0% 79.1%
3c2bA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 42.0 3.62e-01 96.5% 98.6%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.50 40.0 3.50e-01 84.9% 59.5%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4998888 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.73 60.0 4.74e-01 90.7% 80.6%
3330285 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.72 62.0 5.29e-01 94.2% 66.7%
3264196 5067.1.1.13 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT 0.69 55.0 4.42e-01 84.9% 57.0%
5040620 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.69 57.0 4.27e-01 91.9% 54.5%
3925672 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.68 55.0 5.66e-01 89.5% 96.2%
5037670 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.66 57.0 4.51e-01 95.3% 79.4%
3679438 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.66 55.0 5.47e-01 93.0% 95.6%
4520363 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.64 54.0 5.36e-01 100.0% 90.0%
4342929 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.63 52.0 5.13e-01 93.0% 93.7%
5014572 2.21.1.3 beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605 0.63 52.0 4.27e-01 93.0% 47.9%
4972598 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.63 49.0 3.93e-01 86.0% 42.4%
4031095 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 54.0 4.08e-01 93.0% 81.0%
3698982 5050.1.1.26 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UVB_sens_prot 0.63 54.0 3.81e-01 95.3% 65.6%
3286850 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 56.0 4.27e-01 100.0% 76.8%
3869732 1008.1.1.107 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › TEX13 0.62 46.0 3.87e-01 96.5% 45.3%
4520752 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.62 50.0 4.02e-01 91.9% 45.4%
3980513 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.62 52.0 4.14e-01 94.2% 88.3%
3277844 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 55.0 4.21e-01 98.8% 81.5%
4996217 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 51.0 3.90e-01 93.0% 74.8%
4603378 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 53.0 4.01e-01 98.8% 77.7%
3236861 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.60 49.0 4.12e-01 93.0% 95.6%
3391724 109.1.1.7 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_3 0.60 43.0 3.51e-01 79.1% 39.4%
5077137 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.60 50.0 4.28e-01 94.2% 74.5%
4203294 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 54.0 4.09e-01 100.0% 78.0%
4235797 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.59 45.0 3.60e-01 81.4% 60.6%
5035753 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 50.0 3.79e-01 93.0% 78.5%
3673448 192.4.1.37 alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Cas1_AcylT 0.58 48.0 4.36e-01 93.0% 70.0%
3440212 601.18.1.13 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint 0.58 44.0 4.11e-01 80.2% 81.0%
3229885 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.57 43.0 4.11e-01 79.1% 80.6%
3217001 109.12.1.1 alpha superhelices › Repetitive alpha hairpins › C-terminal domain of Ku80 › C-terminal domain of Ku80 › MAS20 0.56 37.0 3.78e-01 86.0% 68.2%
4353495 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.56 47.0 3.75e-01 96.5% 81.1%
5021244 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 50.0 3.91e-01 100.0% 73.0%
4977940 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 47.0 3.63e-01 95.3% 85.5%
4062549 3755.3.1.288 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › LMBR1 0.55 40.0 3.44e-01 75.6% 79.3%
157489 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.55 48.0 4.04e-01 100.0% 100.0%
3980491 628.1.1.1 alpha bundles › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › Fatty acid responsive transcription factor FadR, C-terminal domain › FCD 0.55 43.0 3.73e-01 88.4% 80.6%
4426593 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.54 43.0 3.56e-01 90.7% 78.8%
4941192 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.51 38.0 3.37e-01 77.9% 81.6%
3407816 3832.1.1.1 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 0.51 41.0 3.41e-01 89.5% 67.5%
3598135 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.51 43.0 4.33e-01 93.0% 96.5%