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BML_08182015_6_5m_scaffold_1_prodigal-single.1__X__X__00474
Bact-VirBML_08182015_6_5m_scaffold_1_prodigal-single.1__X__X__00474
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-37_167-299
Domain cluster:
rep: BML_08182015_6_5m_scaffold_1_prodigal-single.1__X__X__00377__D34-55_181-308
D2
high
residues 46-165
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4a4kA01 | 1.20.1500.20 | Mainly Alpha › Up-down Bundle › YheA-like fold › | 0.80 | 35.0 | 3.63e-01 | 100.0% | 44.2% |
| 2qkwA00 | 1.20.1270.140 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto | 0.66 | 35.0 | 3.83e-01 | 100.0% | 60.4% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.64 | 42.0 | 4.64e-01 | 94.2% | 85.9% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.64 | 57.0 | 4.29e-01 | 100.0% | 68.0% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 39.0 | 4.38e-01 | 100.0% | 83.5% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 56.0 | 5.36e-01 | 99.2% | 99.3% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 56.0 | 5.38e-01 | 100.0% | 87.1% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 36.0 | 3.85e-01 | 100.0% | 67.6% |
| 1dxrL02 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.60 | 36.0 | 3.81e-01 | 100.0% | 66.7% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 53.0 | 5.32e-01 | 96.7% | 100.0% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.59 | 39.0 | 4.47e-01 | 81.7% | 92.0% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 52.0 | 4.89e-01 | 100.0% | 90.2% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 38.0 | 3.78e-01 | 80.8% | 66.1% |
| 1m4rB00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 41.0 | 3.91e-01 | 97.5% | 64.5% |
| 1jvmB00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 39.0 | 4.18e-01 | 100.0% | 85.0% |
| 3c8eA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 33.0 | 3.07e-01 | 100.0% | 44.6% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.56 | 50.0 | 4.24e-01 | 99.2% | 70.0% |
| 4mk3A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 34.0 | 3.48e-01 | 100.0% | 61.7% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.55 | 36.0 | 3.66e-01 | 81.7% | 65.3% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 40.0 | 4.21e-01 | 80.8% | 83.5% |
| 1a22A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 51.0 | 4.44e-01 | 100.0% | 69.4% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.55 | 35.0 | 3.55e-01 | 84.2% | 64.1% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 39.0 | 3.08e-01 | 73.3% | 79.3% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 41.0 | 4.15e-01 | 81.7% | 81.2% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.54 | 48.0 | 4.32e-01 | 100.0% | 92.3% |
| 4mtxD00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.53 | 32.0 | 3.55e-01 | 95.0% | 74.7% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.53 | 47.0 | 4.35e-01 | 99.2% | 94.8% |
| 5zr4A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 32.0 | 3.45e-01 | 100.0% | 70.6% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.52 | 42.0 | 3.71e-01 | 84.2% | 73.2% |
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 38.0 | 4.14e-01 | 80.8% | 94.9% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 47.0 | 4.03e-01 | 100.0% | 100.0% |
| 2qksA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 36.0 | 3.80e-01 | 100.0% | 81.1% |
| 1auwA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.51 | 44.0 | 3.58e-01 | 93.3% | 65.8% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.51 | 37.0 | 3.79e-01 | 80.0% | 77.3% |
| 4mudC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 44.0 | 3.59e-01 | 97.5% | 51.4% |
| 3qavA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 36.0 | 3.46e-01 | 73.3% | 86.4% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.51 | 38.0 | 4.01e-01 | 80.0% | 89.1% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 44.0 | 4.15e-01 | 98.3% | 92.7% |
| 6ldkA01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.50 | 36.0 | 3.25e-01 | 80.0% | 52.3% |
| 2j0nB00 | 1.20.1710.10 | Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like | 0.50 | 39.0 | 3.38e-01 | 81.7% | 60.4% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 45.0 | 4.09e-01 | 100.0% | 74.1% |
| 5af7B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 44.0 | 4.17e-01 | 99.2% | 98.6% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3626481 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.80 | 38.0 | 3.96e-01 | 100.0% | 50.0% |
| 3178307 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.79 | 50.0 | 4.57e-01 | 100.0% | 49.7% |
| 3392033 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.75 | 48.0 | 4.60e-01 | 100.0% | 57.0% |
| 5054405 | 606.1.1.1 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop | 0.73 | 49.0 | 5.28e-01 | 100.0% | 82.0% |
| 3787913 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.70 | 44.0 | 3.15e-01 | 100.0% | 21.7% |
| 3455464 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.69 | 36.0 | 3.32e-01 | 100.0% | 39.4% |
| 3220314 | 5054.1.1.1 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan | 0.63 | 39.0 | 3.61e-01 | 100.0% | 48.7% |
| 3414776 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.63 | 38.0 | 3.56e-01 | 100.0% | 49.0% |
| 3813462 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 38.0 | 3.71e-01 | 80.8% | 54.1% |
| 3400182 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.62 | 36.0 | 3.56e-01 | 100.0% | 53.6% |
| 3473217 | 633.23.1.4 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Claudin_2 | 0.61 | 57.0 | 4.65e-01 | 100.0% | 91.9% |
| 3954068 | 633.23.1.7 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › DUF5336 | 0.59 | 54.0 | 5.34e-01 | 97.5% | 95.2% |
| 3599272 | 633.23.1.23 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Amastin | 0.59 | 54.0 | 4.77e-01 | 100.0% | 100.0% |
| 3688032 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.58 | 53.0 | 4.03e-01 | 100.0% | 54.3% |
| 3522138 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 46.0 | 3.83e-01 | 86.7% | 92.4% |
| 3236773 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 51.0 | 4.90e-01 | 97.5% | 95.6% |
| 3878495 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.57 | 52.0 | 4.26e-01 | 100.0% | 89.3% |
| 3929064 | 108.1.1.73 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 | 0.57 | 32.0 | 3.86e-01 | 79.2% | 86.7% |
| 3735230 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.57 | 51.0 | 4.70e-01 | 98.3% | 94.2% |
| 3757027 | 150.1.1.119 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Clusterin | 0.57 | 52.0 | 4.64e-01 | 100.0% | 99.4% |
| 3848969 | 3567.1.1.17 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › DUF4533 | 0.57 | 50.0 | 4.38e-01 | 100.0% | 65.6% |
| 3402376 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.56 | 37.0 | 3.54e-01 | 81.7% | 56.4% |
| 3621378 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 52.0 | 4.62e-01 | 100.0% | 84.8% |
| 3253936 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.56 | 38.0 | 3.68e-01 | 80.8% | 61.5% |
| 3577589 | 150.1.1.100 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › TMD0_ABC | 0.56 | 50.0 | 4.41e-01 | 97.5% | 78.8% |
| 4000084 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.55 | 36.0 | 3.39e-01 | 82.5% | 52.7% |
| 3798299 | 633.22.1.0 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) | 0.55 | 49.0 | 4.16e-01 | 97.5% | 67.0% |
| 3805103 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.55 | 38.0 | 4.10e-01 | 81.7% | 81.9% |
| 3753033 | 108.1.1.26 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5 | 0.55 | 36.0 | 3.88e-01 | 80.8% | 76.2% |
| 4030170 | 3291.1.1.20 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › RIFIN | 0.54 | 47.0 | 3.98e-01 | 96.7% | 56.7% |
| 3596170 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 40.0 | 3.96e-01 | 80.8% | 73.6% |
| 3896876 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.53 | 47.0 | 3.58e-01 | 100.0% | 64.0% |
| 3483494 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.53 | 48.0 | 4.25e-01 | 99.2% | 82.9% |
| 4237962 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.53 | 38.0 | 2.62e-01 | 75.0% | 30.7% |
| 3638822 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.53 | 39.0 | 3.54e-01 | 80.0% | 69.7% |
| 3989810 | 3291.1.1.5 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Relaxase_C | 0.53 | 37.0 | 4.10e-01 | 100.0% | 93.7% |
| 3207974 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.52 | 47.0 | 4.17e-01 | 98.3% | 91.8% |
| 3577231 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 40.0 | 3.75e-01 | 81.7% | 88.0% |
| 3654557 | 609.1.1.1 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg | 0.52 | 43.0 | 4.19e-01 | 100.0% | 82.3% |
| 3789156 | 192.29.1.223 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Syntaxin_2 | 0.52 | 39.0 | 3.52e-01 | 80.8% | 62.9% |
| 3697011 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.52 | 39.0 | 3.42e-01 | 80.8% | 70.0% |
| 3548931 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.52 | 46.0 | 3.37e-01 | 98.3% | 39.7% |
| 4237398 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.51 | 38.0 | 3.42e-01 | 79.2% | 55.4% |
| 3346653 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.51 | 35.0 | 3.70e-01 | 78.3% | 80.0% |
| 3701064 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.50 | 36.0 | 3.31e-01 | 75.0% | 84.4% |
| 2492495 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.50 | 36.0 | 3.36e-01 | 75.8% | 72.3% |
| 3920499 | 611.8.1.1 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne | 0.50 | 37.0 | 3.36e-01 | 78.3% | 74.1% |