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Bcl-2-like_protein
Euk-VirMonkeypox_virus
Bcl-2-like_protein__YP_010377017__Monkeypox_virus__10244
Identity
- Accession:
- YP_010377017 ↗
- Protein ID:
- Bcl-2-like_protein
- Kingdom:
- euk
Quality
71.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Monkeypox_virus
TaxID: 10244
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-72
D2
high
residues 94-213
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06227.18 best | Poxv_Bcl-2-like | 69.3 | 4.60e-19 | 94.2% | 83.3% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2vvwA00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.82 | 77.0 | 7.09e-01 | 100.0% | 92.0% |
| 1ohuA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.73 | 63.0 | 5.70e-01 | 95.0% | 89.7% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.53 | 41.0 | 3.59e-01 | 84.2% | 92.7% |
| 4cs9C00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.52 | 38.0 | 3.51e-01 | 98.3% | 56.4% |
| 2xseA00 | 1.20.120.1440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain | 0.52 | 42.0 | 3.88e-01 | 88.3% | 97.5% |
| 4cs9B02 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.51 | 38.0 | 3.95e-01 | 99.2% | 87.9% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2071357 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.70 | 61.0 | 5.82e-01 | 94.2% | 93.5% |
| 4942190 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.53 | 32.0 | 3.64e-01 | 80.8% | 80.7% |
| 1299701 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.53 | 40.0 | 3.46e-01 | 80.8% | 88.0% |
| 4932900 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.51 | 33.0 | 3.64e-01 | 79.2% | 82.8% |
| 5065872 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.51 | 39.0 | 3.52e-01 | 82.5% | 85.1% |
| 3919862 | 5051.1.1.10 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 | 0.51 | 42.0 | 2.87e-01 | 90.8% | 75.1% |
| 4951266 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.50 | 43.0 | 3.06e-01 | 96.7% | 87.5% |
| 4379938 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.50 | 43.0 | 3.22e-01 | 95.8% | 90.3% |