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Bcl-2_like_protein
Euk-VirLymphocystis_disease_virus_Sa
Bcl-2_like_protein__YP_009342146__Lymphocystis_disease_virus_Sa__1898060
Identity
- Accession:
- YP_009342146 ↗
- Protein ID:
- Bcl-2_like_protein
- Kingdom:
- euk
Quality
73.6
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Iridoviridae›
Lymphocystivirus›
Lymphocystis_disease_virus_Sa
TaxID: 1898060
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 38-166
Domain cluster:
rep: BALF1__YP_001129511__Human_herpesvirus_4_type_2__12509__D29-175
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00452.25 best | Bcl-2 | 37.1 | 5.40e-09 | 72.1% | 88.0% |
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2kbwA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.84 | 80.0 | 7.48e-01 | 100.0% | 90.8% |
| 1lxlA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.79 | 73.0 | 6.05e-01 | 100.0% | 86.0% |
| 3qbrX00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.79 | 74.0 | 6.80e-01 | 100.0% | 92.5% |
| 2imsA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.78 | 71.0 | 6.58e-01 | 100.0% | 92.6% |
| 1f16A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.77 | 71.0 | 6.19e-01 | 100.0% | 73.4% |
| 2kuaA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.76 | 70.0 | 6.59e-01 | 97.7% | 93.4% |
| 2b48A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.76 | 57.0 | 5.53e-01 | 78.3% | 71.3% |
| 2jbyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.73 | 62.0 | 6.32e-01 | 98.4% | 92.1% |
| 6xy4A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.72 | 61.0 | 6.23e-01 | 95.3% | 94.3% |
| 2vvyA01 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.72 | 62.0 | 6.18e-01 | 98.4% | 90.3% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.71 | 65.0 | 6.40e-01 | 98.4% | 94.1% |
| 2vvwA00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.71 | 63.0 | 5.98e-01 | 97.7% | 82.0% |
| 1ddbA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.70 | 62.0 | 5.42e-01 | 97.7% | 92.3% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.61 | 46.0 | 3.98e-01 | 78.3% | 68.5% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 28.0 | 3.38e-01 | 90.7% | 63.6% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.60 | 43.0 | 4.09e-01 | 74.4% | 98.7% |
| 1s7bA00 | 1.10.3730.20 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.59 | 29.0 | 3.17e-01 | 97.7% | 54.7% |
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.56 | 48.0 | 4.38e-01 | 95.3% | 84.8% |
| 1rp3A01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.56 | 30.0 | 3.67e-01 | 77.5% | 80.0% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.54 | 34.0 | 3.79e-01 | 97.7% | 82.0% |
| 2gfpA00 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.53 | 45.0 | 3.34e-01 | 95.3% | 86.7% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 30.0 | 3.36e-01 | 89.1% | 70.6% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.51 | 45.0 | 3.87e-01 | 98.4% | 71.2% |
| 3rlfF04 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.51 | 46.0 | 3.82e-01 | 100.0% | 80.3% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.51 | 23.0 | 1.93e-01 | 94.6% | 23.8% |
| 3w0oA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.51 | 42.0 | 3.56e-01 | 89.1% | 66.7% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.51 | 34.0 | 3.43e-01 | 97.7% | 65.6% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.50 | 36.0 | 3.84e-01 | 97.7% | 86.0% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 51371 | 5000.3.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death | 0.89 | 84.0 | 7.69e-01 | 100.0% | 85.8% |
| 3474099 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.87 | 81.0 | 7.34e-01 | 100.0% | 82.4% |
| 4605105 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.86 | 81.0 | 7.16e-01 | 100.0% | 77.2% |
| 3905764 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.86 | 81.0 | 7.29e-01 | 100.0% | 78.2% |
| 2464246 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.85 | 80.0 | 7.63e-01 | 100.0% | 89.9% |
| 4053747 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.83 | 79.0 | 6.99e-01 | 100.0% | 74.3% |
| 3491658 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.82 | 77.0 | 7.01e-01 | 100.0% | 92.1% |
| 2722110 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.82 | 76.0 | 7.19e-01 | 100.0% | 92.8% |
| 4101698 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.82 | 75.0 | 6.62e-01 | 97.7% | 87.2% |
| 4150301 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.81 | 76.0 | 6.73e-01 | 100.0% | 81.1% |
| 3920242 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.81 | 75.0 | 6.52e-01 | 100.0% | 72.6% |
| 3897842 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.79 | 73.0 | 6.36e-01 | 98.4% | 82.5% |
| 3919650 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.79 | 73.0 | 6.72e-01 | 100.0% | 87.3% |
| 3919852 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.79 | 73.0 | 6.47e-01 | 100.0% | 81.1% |
| 3991072 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.78 | 73.0 | 6.73e-01 | 100.0% | 91.3% |
| 3313 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.77 | 71.0 | 6.19e-01 | 100.0% | 73.4% |
| 461801 | 5000.3.1.3 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Poxv_Bcl-2-like | 0.72 | 63.0 | 5.93e-01 | 95.3% | 79.1% |
| 4237257 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.59 | 35.0 | 4.21e-01 | 92.2% | 85.6% |
| 3712596 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.57 | 50.0 | 4.30e-01 | 94.6% | 97.5% |
| 3931142 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.56 | 37.0 | 3.92e-01 | 83.7% | 73.9% |
| 5017264 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.55 | 43.0 | 3.80e-01 | 96.1% | 56.8% |
| 3838637 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.53 | 38.0 | 2.86e-01 | 76.0% | 94.4% |
| 3204262 | 5051.1.1.15 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › K_trans | 0.51 | 38.0 | 2.86e-01 | 76.7% | 96.7% |