←Back to structures
Bcl-2_like_protein
Euk-VirLymphocystis_disease_virus_Sa
Bcl-2_like_protein__YP_009342225__Lymphocystis_disease_virus_Sa__1898060
Identity
- Accession:
- YP_009342225 ↗
- Protein ID:
- Bcl-2_like_protein
- Kingdom:
- euk
Quality
70.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Iridoviridae›
Lymphocystivirus›
Lymphocystis_disease_virus_Sa
TaxID: 1898060
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-147
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00452.25 best | Bcl-2 | 62.3 | 7.40e-17 | 70.9% | 93.0% |
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2kbwA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.88 | 82.0 | 7.97e-01 | 97.2% | 98.0% |
| 6wh0A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.83 | 76.0 | 7.41e-01 | 96.5% | 100.0% |
| 3qbrX00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.83 | 77.0 | 7.35e-01 | 97.9% | 99.4% |
| 2vm6A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.82 | 76.0 | 7.57e-01 | 97.9% | 99.3% |
| 2imsA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.82 | 74.0 | 6.99e-01 | 95.0% | 97.5% |
| 1f16A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.80 | 75.0 | 6.69e-01 | 100.0% | 81.2% |
| 4uf1A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.79 | 63.0 | 6.51e-01 | 85.8% | 87.4% |
| 1lxlA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.78 | 73.0 | 6.21e-01 | 100.0% | 93.7% |
| 1ohuA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.78 | 72.0 | 6.84e-01 | 100.0% | 95.2% |
| 2jbyA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.77 | 66.0 | 6.93e-01 | 95.7% | 100.0% |
| 6xy4A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.76 | 63.0 | 6.76e-01 | 94.3% | 100.0% |
| 2vvwA00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.73 | 65.0 | 6.39e-01 | 95.7% | 89.3% |
| 2vvyA01 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.72 | 61.0 | 6.32e-01 | 93.6% | 95.5% |
| 1q59A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.64 | 58.0 | 5.43e-01 | 100.0% | 91.9% |
| 2ckoA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.54 | 42.0 | 3.48e-01 | 83.0% | 67.5% |
| 4fm3A00 | 1.20.1270.390 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 28.0 | 3.37e-01 | 84.4% | 72.6% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 40.0 | 3.93e-01 | 78.0% | 80.0% |
| 5haxA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.65e-01 | 87.9% | 71.6% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.52 | 30.0 | 2.95e-01 | 80.1% | 49.7% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.51 | 30.0 | 3.60e-01 | 100.0% | 90.8% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 33.0 | 3.70e-01 | 83.7% | 86.1% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3905764 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.90 | 86.0 | 8.01e-01 | 100.0% | 87.1% |
| 2464246 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.89 | 83.0 | 8.21e-01 | 97.9% | 98.0% |
| 4605105 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.89 | 85.0 | 7.75e-01 | 100.0% | 85.6% |
| 51371 | 5000.3.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death | 0.87 | 83.0 | 7.83e-01 | 100.0% | 95.1% |
| 4053747 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.86 | 81.0 | 7.49e-01 | 99.3% | 82.3% |
| 3920242 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.85 | 81.0 | 7.20e-01 | 100.0% | 80.5% |
| 3505161 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.85 | 81.0 | 7.36e-01 | 100.0% | 85.6% |
| 4101698 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.85 | 79.0 | 7.20e-01 | 97.9% | 95.6% |
| 2823637 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.85 | 80.0 | 7.78e-01 | 98.6% | 100.0% |
| 3925098 | 5000.3.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death | 0.85 | 78.0 | 7.20e-01 | 97.2% | 94.9% |
| 3897842 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.84 | 79.0 | 6.99e-01 | 97.9% | 89.9% |
| 2722110 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.84 | 78.0 | 7.64e-01 | 98.6% | 100.0% |
| 3414662 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.84 | 79.0 | 6.75e-01 | 100.0% | 79.1% |
| 3474099 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.84 | 79.0 | 7.32e-01 | 99.3% | 90.0% |
| 2672135 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.83 | 79.0 | 7.47e-01 | 100.0% | 96.3% |
| 4150301 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.83 | 79.0 | 7.16e-01 | 100.0% | 88.9% |
| 3875955 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.83 | 78.0 | 6.98e-01 | 100.0% | 87.3% |
| 3991072 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.82 | 77.0 | 7.38e-01 | 100.0% | 100.0% |
| 3491658 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.82 | 77.0 | 7.26e-01 | 100.0% | 98.8% |
| 51365 | 5000.3.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death | 0.82 | 77.0 | 6.83e-01 | 100.0% | 80.2% |
| 2488153 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.82 | 76.0 | 7.22e-01 | 99.3% | 93.3% |
| 3893197 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.81 | 75.0 | 6.92e-01 | 97.9% | 92.6% |
| 3919852 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.81 | 75.0 | 6.83e-01 | 98.6% | 90.0% |
| 3231057 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.80 | 75.0 | 6.95e-01 | 100.0% | 93.1% |
| 3313 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.80 | 75.0 | 6.69e-01 | 100.0% | 81.2% |
| 1949072 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.80 | 75.0 | 7.22e-01 | 98.6% | 98.1% |
| 3919650 | 5000.3.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 | 0.79 | 73.0 | 6.91e-01 | 98.6% | 97.0% |
| 1874023 | 5000.3.1.2 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2,BH4 | 0.72 | 67.0 | 5.78e-01 | 100.0% | 95.3% |
| 51362 | 5000.3.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death | 0.72 | 65.0 | 6.08e-01 | 97.9% | 88.2% |
| 4928768 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.63 | 43.0 | 4.83e-01 | 78.7% | 92.4% |
| 5027059 | 3352.1.1.48 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › DUF2079 | 0.61 | 43.0 | 3.09e-01 | 70.9% | 50.4% |
| 3613749 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 40.0 | 3.72e-01 | 74.5% | 93.7% |
| 4947351 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.52 | 36.0 | 3.35e-01 | 70.2% | 58.3% |
| 3395581 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 35.0 | 3.57e-01 | 83.7% | 71.9% |