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Bifunctional_metallophosphatase_5-nucleotidase
Euk-VirPandoravirus_neocaledonia
Bifunctional_metallophosphatase_5-nucleotidase__YP_009482527__Pandoravirus_neocaledonia__2107708
Identity
- Accession:
- YP_009482527 ↗
- Protein ID:
- Bifunctional_metallophosphatase_5-nucleotidase
- Kingdom:
- euk
Quality
61.4
mean pLDDT
Cluster
View cluster (11 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 15-132_277-344
D2
medium
residues 157-276
Domain cluster:
rep: Bifunctional_metallophosphatase_5-nucleotidase__YP_009481387__Pandoravirus_macleodensis__2107707__D118-206
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ztvA01 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.75 | 67.0 | 4.67e-01 | 94.2% | 38.7% |
| 2m9mA00 | 3.40.50.10130 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.65 | 43.0 | 4.09e-01 | 90.0% | 56.8% |
| 4qtpD00 | 3.30.750.24 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain | 0.62 | 48.0 | 4.97e-01 | 85.0% | 86.1% |
| 3dorA03 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.61 | 55.0 | 4.33e-01 | 100.0% | 61.0% |
| 3jyhA01 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.60 | 52.0 | 3.95e-01 | 95.8% | 83.8% |
| 2e2oA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.60 | 43.0 | 4.18e-01 | 75.8% | 67.2% |
| 3d6jA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.58 | 41.0 | 3.88e-01 | 72.5% | 92.3% |
| 1ujnA01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 42.0 | 3.84e-01 | 77.5% | 75.8% |
| 1yirA00 | 3.20.140.10 | Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase | 0.57 | 52.0 | 3.61e-01 | 100.0% | 75.1% |
| 1yj7D02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.56 | 37.0 | 4.20e-01 | 91.7% | 92.0% |
| 1ybeB01 | 3.20.140.10 | Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase | 0.56 | 51.0 | 3.55e-01 | 100.0% | 75.9% |
| 2im5A00 | 3.20.140.10 | Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase | 0.56 | 51.0 | 3.57e-01 | 100.0% | 74.0% |
| 4o1hA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 41.0 | 4.17e-01 | 75.8% | 80.7% |
| 2pt7G01 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.56 | 36.0 | 4.23e-01 | 70.0% | 98.7% |
| 4o53A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.56 | 51.0 | 3.98e-01 | 100.0% | 64.1% |
| 4l4qA03 | 3.30.300.10 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.55 | 38.0 | 3.84e-01 | 71.7% | 86.4% |
| 2v82A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.54 | 43.0 | 3.61e-01 | 100.0% | 50.2% |
| 2bdqA00 | 3.20.20.380 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Copper homeostasis (CutC) domain | 0.53 | 48.0 | 4.02e-01 | 100.0% | 67.0% |
| 7xjrA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.53 | 48.0 | 3.63e-01 | 99.2% | 46.9% |
| 1egaA02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.51 | 40.0 | 4.21e-01 | 100.0% | 96.2% |
| 1gehA02 | 3.20.20.110 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain | 0.51 | 46.0 | 3.44e-01 | 100.0% | 49.8% |
| 2jgdB02 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.50 | 42.0 | 3.09e-01 | 90.8% | 55.5% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4077085 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.76 | 68.0 | 4.85e-01 | 94.2% | 43.8% |
| 2640332 | 3979.1.1.0 ↗ | a+b four layers › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain | 0.66 | 52.0 | 3.74e-01 | 82.5% | 33.4% |
| 5016234 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.65 | 40.0 | 4.68e-01 | 70.8% | 88.2% |
| 3639915 | 2486.1.1.1 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 | 0.63 | 56.0 | 4.17e-01 | 94.2% | 81.0% |
| 1099098 | 2486.1.1.7 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Peptidase_S41 | 0.62 | 55.0 | 4.08e-01 | 100.0% | 67.2% |
| 3214730 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.61 | 37.0 | 4.25e-01 | 70.8% | 84.7% |
| 3496315 | 2002.1.1.96 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › S-methyl_trans | 0.61 | 55.0 | 3.94e-01 | 100.0% | 52.7% |
| 5058107 | 7517.1.1.1 ↗ | a/b three-layered sandwiches › Nucleoside hydrolase › Nucleoside hydrolase › Nucleoside hydrolase › IU_nuc_hydro | 0.61 | 44.0 | 3.37e-01 | 76.7% | 59.0% |
| 3988694 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.60 | 38.0 | 4.30e-01 | 90.0% | 85.6% |
| 3586805 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.60 | 37.0 | 4.29e-01 | 91.7% | 88.2% |
| 5037775 | 327.1.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Alpha-lytic protease prodomain › Alpha-lytic protease prodomain | 0.59 | 33.0 | 4.05e-01 | 70.8% | 96.9% |
| 4215086 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.59 | 46.0 | 4.55e-01 | 95.0% | 78.5% |
| 3786473 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.59 | 40.0 | 4.41e-01 | 70.0% | 90.5% |
| 4379426 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.58 | 36.0 | 4.04e-01 | 70.8% | 81.1% |
| 5069330 | 7575.1.1.4 ↗ | a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › Peptidase_C11 | 0.58 | 49.0 | 4.01e-01 | 92.5% | 95.1% |
| 3884000 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.58 | 36.0 | 4.02e-01 | 71.7% | 82.2% |
| 5039350 | 327.6.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › FeS_assembly_P | 0.58 | 39.0 | 4.20e-01 | 90.0% | 83.0% |
| 4147566 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.57 | 41.0 | 4.14e-01 | 74.2% | 73.3% |
| 4838897 | 327.10.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › Ribosomal_S7e | 0.57 | 35.0 | 4.01e-01 | 72.5% | 84.7% |
| 4927819 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.56 | 36.0 | 4.24e-01 | 70.0% | 97.5% |
| 3788787 | 5104.1.1.3 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 | 0.56 | 41.0 | 3.84e-01 | 76.7% | 87.3% |
| 3926173 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.56 | 40.0 | 4.50e-01 | 90.0% | 98.9% |
| None | — | 0.56 | 41.0 | 3.71e-01 | 77.5% | 74.7% | |
| 5057363 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.56 | 33.0 | 4.05e-01 | 88.3% | 100.0% |
| 4934962 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.56 | 32.0 | 3.92e-01 | 88.3% | 100.0% |
| 4295505 | 327.11.1.7 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_NusA_2nd | 0.56 | 34.0 | 3.91e-01 | 93.3% | 85.9% |
| 3210757 | 327.4.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain | 0.55 | 35.0 | 3.87e-01 | 70.8% | 82.2% |
| 5031799 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.55 | 32.0 | 3.92e-01 | 88.3% | 98.6% |
| 5045447 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.55 | 33.0 | 3.91e-01 | 85.0% | 100.0% |
| 5034952 | 2006.1.1.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase | 0.54 | 39.0 | 3.04e-01 | 97.5% | 33.6% |
| 3290764 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.54 | 37.0 | 4.24e-01 | 71.7% | 98.8% |
| 4854112 | 327.10.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › Ribosomal_S7e | 0.54 | 37.0 | 4.13e-01 | 93.3% | 93.5% |
| 162257 | 2002.4.1.1 ↗ | a/b barrels › TIM beta/alpha-barrel › Nicotinate/Quinolinate PRTase C-terminal domain-like › Nicotinate/Quinolinate PRTase C-terminal domain-like › NAPRTase | 0.53 | 44.0 | 3.44e-01 | 92.5% | 41.7% |
| 4846666 | 327.10.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › Ribosomal_S7e | 0.53 | 35.0 | 3.92e-01 | 93.3% | 91.8% |
| 3594135 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.53 | 36.0 | 3.86e-01 | 96.7% | 82.0% |
| 3294828 | 327.11.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_2 | 0.53 | 36.0 | 3.67e-01 | 70.8% | 75.8% |
| 3966083 | 2484.1.1.37 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase | 0.53 | 38.0 | 3.90e-01 | 77.5% | 77.4% |
| 1421547 | 327.10.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related › Ribosomal_S7e | 0.53 | 33.0 | 3.66e-01 | 90.0% | 83.0% |
| 3624068 | 327.18.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A › Ribosomal_S7e | 0.52 | 33.0 | 3.62e-01 | 90.0% | 78.9% |
| 4935616 | 2007.1.1.15 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF2124 | 0.52 | 41.0 | 3.79e-01 | 92.5% | 64.5% |
| 3225023 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.52 | 40.0 | 4.24e-01 | 90.0% | 92.4% |
| 5059170 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.52 | 39.0 | 3.36e-01 | 92.5% | 49.5% |
| 5049100 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.52 | 42.0 | 3.74e-01 | 88.3% | 62.2% |
| None | — | 0.52 | 46.0 | 3.58e-01 | 100.0% | 68.7% | |
| 4940908 | 7573.1.1.3 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyl_synth | 0.52 | 45.0 | 4.32e-01 | 94.2% | 86.7% |
| 4431988 | 327.11.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_2 | 0.51 | 38.0 | 4.08e-01 | 92.5% | 90.5% |
| 5886 | 327.2.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › BolA-like › BolA-like › BolA | 0.51 | 35.0 | 3.64e-01 | 93.3% | 75.2% |
| 3972244 | 7522.1.1.0 ↗ | a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like | 0.51 | 41.0 | 3.62e-01 | 88.3% | 100.0% |
| 5055194 | 327.18.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A | 0.51 | 29.0 | 3.60e-01 | 86.7% | 100.0% |
| 3289704 | 7524.1.1.1 ↗ | a/b three-layered sandwiches › ALDH-like › ALDH-like › ALDH-like › Aldedh | 0.50 | 37.0 | 3.17e-01 | 99.2% | 46.5% |
| 4932902 | 7573.1.1.1 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran | 0.50 | 44.0 | 4.23e-01 | 95.0% | 85.9% |
D3
medium
residues 356-377_412-451