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CAKLQA020000001.1__CAH1067960.1__SAMEA5780030_00005__00005

Bact-Vir

CAKLQA020000001.1__CAH1067960.1__SAMEA5780030_00005__00005

Identity

Kingdom:
phage

Quality

89.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-76
PDB
Domain cluster: representative
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.84 58.0 6.66e-01 87.3% 98.1%
7e5aB02 1.20.1000.10 Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain 0.82 65.0 4.80e-01 87.3% 36.0%
1nlxA00 1.20.120.320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen 0.76 55.0 4.87e-01 93.0% 52.9%
2kseA00 1.20.5.1040 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Sensor protein qsec. 0.75 63.0 6.14e-01 100.0% 83.1%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.74 62.0 4.81e-01 100.0% 42.0%
3bg2A03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.73 63.0 5.68e-01 98.6% 69.8%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.72 52.0 4.02e-01 81.7% 35.1%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 61.0 5.19e-01 100.0% 58.3%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.71 62.0 4.83e-01 98.6% 48.4%
1ciiA02 3.30.305.10 Alpha Beta › 2-Layer Sandwich › Colicin Ia; domain 2 › Colicin Ia; domain 2 0.70 47.0 4.17e-01 100.0% 48.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.70 52.0 4.63e-01 80.3% 78.4%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 63.0 5.54e-01 100.0% 90.3%
4mk6A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 56.0 4.13e-01 90.1% 71.8%
4yzgA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.68 57.0 3.77e-01 93.0% 29.6%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.68 55.0 4.39e-01 90.1% 44.9%
6cnzF00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.67 53.0 4.03e-01 84.5% 38.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 50.0 4.15e-01 78.9% 48.3%
3h6pC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 49.0 5.31e-01 97.2% 100.0%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.66 46.0 4.61e-01 76.1% 71.8%
3r0qA02 2.70.160.11 Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 0.66 59.0 4.22e-01 100.0% 63.9%
2bskB00 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.65 54.0 5.59e-01 91.5% 100.0%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 55.0 5.41e-01 95.8% 89.7%
2xmoA02 1.10.246.180 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.65 46.0 4.39e-01 85.9% 62.8%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.65 47.0 3.86e-01 84.5% 41.0%
3ic9A02 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.64 56.0 5.63e-01 100.0% 100.0%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.64 58.0 4.77e-01 100.0% 60.0%
7d3uC01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 56.0 4.94e-01 100.0% 66.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 45.0 4.16e-01 85.9% 57.6%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 48.0 4.35e-01 97.2% 59.8%
1jb0K00 1.20.860.20 Mainly Alpha › Up-down Bundle › Alpha-t-alpha › Photosystem I PsaK, reaction centre 0.63 40.0 4.57e-01 77.5% 100.0%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 51.0 4.44e-01 100.0% 59.0%
2xseA00 1.20.120.1440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain 0.63 50.0 3.95e-01 90.1% 89.3%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.62 50.0 4.05e-01 94.4% 45.9%
7b00A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.62 50.0 3.14e-01 93.0% 51.7%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 43.0 4.10e-01 73.2% 91.5%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.61 55.0 4.43e-01 98.6% 63.9%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.61 45.0 4.65e-01 77.5% 82.1%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.61 54.0 3.46e-01 95.8% 31.4%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.61 43.0 3.94e-01 100.0% 57.1%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 51.0 3.58e-01 91.5% 43.7%
3bqyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 49.0 3.89e-01 94.4% 42.7%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.60 42.0 4.77e-01 90.1% 100.0%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 52.0 4.88e-01 100.0% 95.6%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.60 48.0 4.69e-01 90.1% 78.8%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 51.0 4.60e-01 97.2% 70.1%
6g94A00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.59 50.0 3.70e-01 94.4% 37.2%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 50.0 3.89e-01 95.8% 42.4%
4iv6B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 42.0 3.59e-01 93.0% 46.6%
3iylB02 1.10.2050.10 Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 0.58 45.0 3.70e-01 84.5% 68.7%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 51.0 3.67e-01 98.6% 85.2%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.58 51.0 4.10e-01 94.4% 66.9%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 48.0 3.36e-01 100.0% 80.4%
1nu7D02 1.20.120.760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle, domain 2 0.57 45.0 3.73e-01 90.1% 47.7%
3o60A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 47.0 3.55e-01 93.0% 71.4%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.57 52.0 4.08e-01 100.0% 57.9%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 49.0 3.83e-01 95.8% 45.0%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 50.0 4.45e-01 100.0% 74.0%
4mndA02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.57 45.0 3.31e-01 94.4% 31.9%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.57 50.0 4.83e-01 100.0% 89.0%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 47.0 4.07e-01 95.8% 59.1%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.56 46.0 4.78e-01 95.8% 100.0%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 48.0 4.71e-01 95.8% 88.3%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.55 49.0 4.78e-01 100.0% 91.1%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 49.0 4.11e-01 100.0% 63.6%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.55 46.0 4.33e-01 100.0% 76.1%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 46.0 4.67e-01 100.0% 91.7%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.55 45.0 3.88e-01 95.8% 56.9%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.55 47.0 4.63e-01 100.0% 89.6%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 46.0 4.59e-01 95.8% 92.0%
4hfvA02 6.10.280.170 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Substrate of the Dot/Icm secretion system 0.54 45.0 4.54e-01 90.1% 98.6%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 39.0 3.94e-01 93.0% 75.7%
4dhxB00 1.10.246.140 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 0.54 44.0 4.20e-01 98.6% 87.9%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.53 48.0 4.47e-01 100.0% 88.9%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.52 47.0 4.43e-01 98.6% 82.4%
ECOD (86)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4524703 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.85 73.0 6.18e-01 100.0% 58.3%
3398929 5041.1.1.32 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 0.84 79.0 7.23e-01 100.0% 78.9%
4996194 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.84 70.0 6.40e-01 94.4% 70.0%
4996138 5069.1.3.136 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › MS_channel_1st 0.83 70.0 5.51e-01 94.4% 46.7%
3610065 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.80 74.0 4.72e-01 100.0% 29.8%
3209602 5042.1.1.0 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region 0.80 70.0 6.87e-01 100.0% 89.3%
4991390 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.80 66.0 5.97e-01 98.6% 66.3%
4928145 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.79 67.0 6.49e-01 97.2% 82.5%
4033954 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.79 66.0 5.92e-01 100.0% 66.0%
3057373 1174.1.1.1 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 0.78 62.0 4.69e-01 84.5% 41.0%
4964984 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.78 64.0 5.66e-01 94.4% 63.0%
3700186 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.78 70.0 4.60e-01 100.0% 26.9%
3188738 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.77 70.0 4.53e-01 100.0% 26.3%
4027540 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.77 68.0 5.22e-01 100.0% 43.8%
3585359 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.77 68.0 4.48e-01 100.0% 25.0%
4940986 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.77 64.0 5.81e-01 94.4% 68.4%
3269852 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.76 68.0 4.48e-01 100.0% 26.8%
3744793 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.76 67.0 4.43e-01 100.0% 31.2%
3314055 5042.1.1.0 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region 0.76 66.0 6.51e-01 98.6% 90.5%
3957435 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.75 67.0 5.59e-01 100.0% 58.3%
3786455 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.75 67.0 4.38e-01 100.0% 28.7%
3208058 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.74 66.0 4.29e-01 100.0% 99.7%
4981299 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 60.0 5.38e-01 100.0% 63.0%
4951918 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 60.0 5.48e-01 93.0% 66.3%
5003923 5042.1.1.1 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA 0.74 59.0 5.98e-01 91.5% 87.1%
4324592 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.73 62.0 5.58e-01 94.4% 67.0%
3428080 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.73 65.0 4.34e-01 100.0% 27.3%
5064072 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.73 60.0 5.50e-01 94.4% 70.0%
1252012 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.72 62.0 5.53e-01 94.4% 71.7%
3272165 4207.1.1.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) 0.72 59.0 5.15e-01 98.6% 59.1%
5078272 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.72 64.0 4.19e-01 97.2% 43.5%
4964387 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.72 58.0 5.18e-01 88.7% 70.0%
5038339 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.72 57.0 5.41e-01 93.0% 72.9%
5002748 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 50.0 4.91e-01 80.3% 69.3%
3846684 1174.1.1.1 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › TMEM175 0.71 56.0 3.92e-01 88.7% 26.4%
3366877 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.70 55.0 3.63e-01 85.9% 56.9%
5012522 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.70 55.0 5.18e-01 94.4% 70.0%
3782284 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.68 60.0 4.31e-01 100.0% 77.1%
3606823 3476.1.1.0 alpha arrays › RecQL4 helicase N-terminal domain › RecQL4 helicase N-terminal domain › RecQL4 helicase N-terminal domain 0.68 45.0 4.83e-01 73.2% 80.0%
4489485 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.68 48.0 3.49e-01 74.6% 28.7%
3205696 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 58.0 4.79e-01 100.0% 51.9%
5019215 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.68 49.0 3.22e-01 77.5% 17.7%
5068089 283.1.1.0 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase 0.68 55.0 4.74e-01 97.2% 55.7%
None 0.68 59.0 3.99e-01 100.0% 26.0%
3787585 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.68 48.0 4.21e-01 74.6% 57.1%
4942098 5042.1.1.1 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA 0.67 52.0 5.35e-01 93.0% 89.7%
4947641 5042.1.1.0 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region 0.66 54.0 5.57e-01 93.0% 98.5%
3990854 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.65 52.0 4.77e-01 84.5% 70.0%
3891023 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.65 48.0 3.61e-01 84.5% 31.7%
3805996 192.10.1.7 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › HisKA 0.63 49.0 4.84e-01 97.2% 78.7%
3988260 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.63 49.0 3.19e-01 84.5% 18.5%
3436578 3755.4.1.17 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N 0.63 54.0 4.29e-01 97.2% 46.7%
3370743 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 47.0 4.56e-01 83.1% 71.2%
3694629 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.62 48.0 4.60e-01 87.3% 72.5%
3982421 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.62 48.0 4.75e-01 98.6% 78.7%
3282043 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.62 50.0 4.78e-01 90.1% 88.2%
4520394 5063.1.1.1 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › PSI_PSAK 0.62 51.0 5.24e-01 94.4% 100.0%
3164951 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.62 56.0 4.16e-01 100.0% 41.2%
4010395 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.62 47.0 4.75e-01 95.8% 82.9%
4639996 150.7.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PE › PE › PE 0.61 53.0 4.91e-01 95.8% 97.8%
3948970 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.61 46.0 4.15e-01 94.4% 55.5%
3510392 6157.1.1.1 alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP 0.61 51.0 4.47e-01 94.4% 83.6%
3273941 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.61 55.0 3.80e-01 100.0% 75.2%
3416168 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.61 53.0 3.81e-01 100.0% 68.2%
3924838 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.61 51.0 3.63e-01 97.2% 28.7%
3594138 604.32.1.0 alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY 0.60 49.0 4.11e-01 95.8% 52.5%
3954313 150.5.1.52 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE 0.60 50.0 4.60e-01 95.8% 73.7%
4117096 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.59 49.0 3.65e-01 93.0% 74.2%
4817720 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.59 48.0 3.24e-01 91.5% 22.2%
4116779 603.1.1.174 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HisKA 0.59 47.0 4.62e-01 87.3% 80.0%
3297770 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.59 47.0 4.44e-01 88.7% 71.8%
3486748 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 52.0 4.59e-01 100.0% 66.7%
5039649 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 53.0 4.41e-01 100.0% 85.0%
3264065 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.58 48.0 4.67e-01 93.0% 80.0%
4957467 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.58 50.0 3.39e-01 100.0% 45.4%
3184140 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.58 52.0 4.46e-01 100.0% 72.2%
3581368 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.58 51.0 3.94e-01 95.8% 51.3%
4890998 148.1.3.28 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_11 0.58 47.0 3.16e-01 93.0% 45.6%
3628093 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.56 50.0 4.42e-01 100.0% 68.6%
3971109 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.55 46.0 4.57e-01 94.4% 90.7%
3364683 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.55 47.0 4.42e-01 98.6% 97.8%
3945620 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.55 48.0 4.47e-01 100.0% 88.9%
3609435 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.54 49.0 4.53e-01 100.0% 85.6%
3656598 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 47.0 3.78e-01 97.2% 63.8%
None 0.52 44.0 3.34e-01 100.0% 67.4%
4312324 605.1.1.306 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PF30649 0.52 42.0 4.17e-01 95.8% 85.3%
D2 high residues 78-216
PDB
Domain cluster: representative
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.80 57.0 6.62e-01 92.8% 98.1%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 65.0 6.76e-01 99.3% 92.2%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.79 59.0 6.38e-01 97.8% 90.8%
2l10A00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.78 62.0 5.93e-01 100.0% 73.4%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 59.0 4.78e-01 79.1% 78.3%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.77 57.0 6.36e-01 90.6% 94.6%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.77 67.0 5.09e-01 93.5% 92.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 56.0 5.16e-01 74.8% 82.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.76 63.0 6.62e-01 92.8% 97.6%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 58.0 5.20e-01 79.9% 68.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 57.0 5.17e-01 79.1% 88.8%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.76 55.0 5.64e-01 74.8% 88.0%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 57.0 4.75e-01 79.1% 78.0%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 57.0 6.17e-01 95.0% 94.9%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.73 43.0 5.31e-01 98.6% 94.1%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 58.0 6.04e-01 100.0% 90.8%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.73 51.0 5.21e-01 71.9% 85.2%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.71 64.0 4.90e-01 100.0% 92.8%
4ciuA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 52.0 4.68e-01 75.5% 82.8%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.71 51.0 5.20e-01 73.4% 100.0%
8h8jC01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.71 60.0 4.77e-01 90.6% 84.5%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 58.0 5.85e-01 90.6% 98.6%
3a7kB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 55.0 4.47e-01 97.1% 46.9%
1q90B00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.67 62.0 5.31e-01 100.0% 82.1%
6todA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 59.0 4.60e-01 97.8% 86.9%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 55.0 5.71e-01 95.0% 96.2%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.66 58.0 4.52e-01 96.4% 76.9%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.65 57.0 4.87e-01 95.0% 88.3%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.65 58.0 5.27e-01 99.3% 90.4%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 52.0 4.18e-01 84.9% 82.3%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.64 48.0 4.31e-01 78.4% 81.7%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.64 49.0 4.70e-01 79.9% 81.4%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 50.0 4.31e-01 83.5% 80.0%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 42.0 4.16e-01 86.3% 64.4%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 51.0 4.42e-01 87.8% 84.2%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.62 57.0 5.17e-01 100.0% 82.0%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.60 54.0 4.69e-01 99.3% 75.2%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 52.0 4.13e-01 92.1% 80.1%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 48.0 3.97e-01 86.3% 75.1%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 47.0 3.64e-01 87.8% 94.0%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.58 44.0 4.23e-01 79.1% 87.3%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.55 50.0 4.84e-01 100.0% 100.0%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 44.0 3.78e-01 84.9% 81.7%
5tj5E00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.55 48.0 4.91e-01 98.6% 97.1%
6o7uc01 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.54 49.0 4.45e-01 99.3% 82.6%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.54 49.0 4.48e-01 100.0% 89.5%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.52 35.0 3.91e-01 93.5% 86.4%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3441615 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.84 79.0 6.78e-01 100.0% 91.4%
4949599 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.84 73.0 7.23e-01 96.4% 87.6%
3949246 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.82 75.0 7.01e-01 100.0% 80.6%
3480861 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.82 63.0 5.01e-01 79.1% 86.3%
3459613 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.81 76.0 7.12e-01 100.0% 93.3%
4258378 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.81 75.0 5.91e-01 98.6% 91.9%
3967683 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.80 65.0 6.36e-01 100.0% 79.3%
3228351 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.79 74.0 6.92e-01 100.0% 92.7%
4004039 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.79 60.0 5.09e-01 79.9% 59.1%
3257358 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.77 59.0 4.95e-01 79.1% 82.7%
4671383 4177.1.1.9 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom 0.77 59.0 4.82e-01 79.1% 90.6%
3275930 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.77 58.0 4.77e-01 79.1% 75.6%
3859895 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 58.0 4.22e-01 79.1% 47.5%
3212831 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.76 71.0 6.38e-01 100.0% 84.9%
3681881 192.29.1.46 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF1110 0.75 70.0 6.56e-01 100.0% 99.4%
3731974 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.75 51.0 5.72e-01 93.5% 87.3%
3233475 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.75 68.0 6.64e-01 97.8% 98.7%
3420023 633.21.1.18 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom 0.74 51.0 4.82e-01 70.5% 71.5%
3546060 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.72 55.0 4.28e-01 79.1% 78.0%
3377464 3755.3.1.285 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A 0.72 63.0 6.00e-01 100.0% 80.0%
4927854 5069.1.1.44 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › CopD 0.72 65.0 6.17e-01 97.1% 98.8%
3489411 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.72 64.0 6.09e-01 98.6% 82.4%
3211838 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.72 55.0 4.79e-01 79.9% 76.1%
4475459 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.71 58.0 5.82e-01 89.9% 86.4%
3758589 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.71 54.0 4.57e-01 79.1% 78.7%
5021299 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 65.0 5.76e-01 100.0% 76.9%
3709988 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.70 53.0 5.05e-01 79.9% 85.5%
5053834 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 62.0 5.81e-01 96.4% 78.8%
3789188 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.70 53.0 4.28e-01 78.4% 67.1%
3649076 3939.1.1.207 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › NET2A 0.68 65.0 5.76e-01 100.0% 81.6%
3513855 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.68 47.0 4.67e-01 70.5% 79.3%
3517893 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.68 53.0 4.34e-01 81.3% 79.6%
3306059 3755.4.1.46 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › NET2A 0.66 62.0 5.13e-01 100.0% 80.4%
5031982 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.66 60.0 5.67e-01 98.6% 81.8%
3782312 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.66 54.0 4.23e-01 87.8% 70.5%
3463685 601.1.2.68 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DUF1218 0.66 57.0 5.70e-01 95.0% 91.0%
4028318 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 52.0 5.47e-01 97.8% 93.6%
4944191 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 58.0 5.87e-01 95.7% 95.0%
3171851 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 55.0 5.29e-01 100.0% 80.6%
3402136 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.65 53.0 4.37e-01 87.1% 72.7%
5045646 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 56.0 5.56e-01 96.4% 96.5%
3599032 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.63 56.0 4.71e-01 96.4% 79.6%
5012794 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.62 58.0 4.15e-01 97.8% 87.6%
4126623 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 52.0 3.41e-01 89.9% 51.8%
3189586 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.62 44.0 4.22e-01 79.9% 63.7%
3732232 109.3.1.293 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ran-binding 0.61 52.0 5.05e-01 91.4% 86.5%
3737139 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.60 53.0 4.18e-01 95.7% 69.1%
3454885 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.58 50.0 5.06e-01 91.4% 96.3%
3718775 633.6.1.6 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C 0.58 47.0 4.45e-01 84.9% 85.9%
5037027 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.58 52.0 5.12e-01 98.6% 100.0%
3436207 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.57 48.0 4.88e-01 91.4% 91.4%
3686404 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.57 49.0 4.61e-01 91.4% 83.6%
3636681 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.56 52.0 3.98e-01 100.0% 61.3%
3998675 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.55 49.0 4.17e-01 98.6% 65.7%
3734036 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.51 47.0 3.21e-01 100.0% 36.5%
3248423 109.42.1.1 alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain › SHPRH_helical-1st 0.51 46.0 4.01e-01 97.1% 79.5%