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CAKLQA020000002.1__CAH1068948.1__SAMEA5780030_00089__00023
Bact-VirCAKLQA020000002.1__CAH1068948.1__SAMEA5780030_00089__00023
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 35-87
Domain cluster:
representative
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3c8tA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.88 | 66.0 | 5.25e-01 | 79.2% | 46.4% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.83 | 62.0 | 5.86e-01 | 79.2% | 67.7% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.82 | 66.0 | 3.97e-01 | 86.8% | 14.7% |
| 5xnyA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.81 | 60.0 | 4.71e-01 | 79.2% | 40.2% |
| 1l5jA03 | 3.40.1060.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 | 0.81 | 62.0 | 4.28e-01 | 83.0% | 25.4% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.81 | 63.0 | 4.93e-01 | 84.9% | 42.7% |
| 2cazD00 | 6.10.140.820 | Special › Helix non-globular › Helix Hairpins › | 0.79 | 61.0 | 5.90e-01 | 84.9% | 80.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.76 | 63.0 | 5.38e-01 | 92.5% | 87.2% |
| 3zxsC02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.74 | 59.0 | 4.20e-01 | 86.8% | 96.8% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 57.0 | 5.55e-01 | 86.8% | 82.8% |
| 4dnnA00 | 1.20.5.4010 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.72 | 56.0 | 5.78e-01 | 86.8% | 92.0% |
| 4i5sB03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.72 | 59.0 | 5.25e-01 | 90.6% | 72.0% |
| 4cpgA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.72 | 59.0 | 5.41e-01 | 90.6% | 69.6% |
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.71 | 58.0 | 4.43e-01 | 92.5% | 41.1% |
| 1ailA00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.71 | 60.0 | 5.47e-01 | 94.3% | 77.1% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.71 | 54.0 | 5.16e-01 | 84.9% | 93.7% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 58.0 | 5.45e-01 | 90.6% | 73.8% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.70 | 60.0 | 3.78e-01 | 98.1% | 41.3% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.70 | 55.0 | 4.89e-01 | 90.6% | 59.5% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.70 | 53.0 | 5.04e-01 | 84.9% | 90.6% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.70 | 56.0 | 5.77e-01 | 88.7% | 96.0% |
| 6dv2G02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.70 | 49.0 | 3.31e-01 | 75.5% | 21.2% |
| 2jaeA03 | 1.20.1440.240 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.69 | 57.0 | 4.64e-01 | 92.5% | 52.5% |
| 1u5eA01 | 6.10.250.220 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.69 | 52.0 | 5.26e-01 | 84.9% | 90.6% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.69 | 56.0 | 5.78e-01 | 92.5% | 100.0% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 54.0 | 5.09e-01 | 88.7% | 70.8% |
| 2xzmO02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.68 | 57.0 | 5.25e-01 | 96.2% | 80.0% |
| 5b1aH00 | 1.10.10.140 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Cytochrome c oxidase, subunit VIb | 0.67 | 56.0 | 4.97e-01 | 98.1% | 64.6% |
| 2ld7B00 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.67 | 50.0 | 4.50e-01 | 86.8% | 57.3% |
| 3kd3A02 | 1.10.150.210 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 | 0.67 | 55.0 | 5.35e-01 | 100.0% | 83.3% |
| 7ymiD01 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.65 | 55.0 | 3.87e-01 | 96.2% | 64.4% |
| 3ed5A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.64 | 57.0 | 4.80e-01 | 96.2% | 88.1% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.64 | 50.0 | 4.40e-01 | 90.6% | 64.4% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.63 | 50.0 | 5.11e-01 | 90.6% | 100.0% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 52.0 | 4.69e-01 | 98.1% | 70.5% |
| 2wglA00 | 1.10.4190.10 | Mainly Alpha › Orthogonal Bundle › Urease accessory protein UreF › Urease accessory protein UreF | 0.63 | 54.0 | 3.66e-01 | 100.0% | 35.9% |
| 4jvyB00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.62 | 53.0 | 3.67e-01 | 98.1% | 92.6% |
| 2kkmA01 | 1.20.1440.170 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Translation machinery-associated protein 16-like | 0.62 | 48.0 | 3.78e-01 | 90.6% | 67.2% |
| 2cr7A01 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.62 | 45.0 | 4.36e-01 | 86.8% | 68.3% |
| 3gfaA00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.60 | 51.0 | 3.48e-01 | 96.2% | 82.1% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 47.0 | 4.21e-01 | 94.3% | 77.4% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.59 | 46.0 | 3.16e-01 | 88.7% | 25.8% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3410594 | 4177.1.1.6 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg | 0.90 | 73.0 | 4.69e-01 | 84.9% | 76.1% |
| 4463998 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.85 | 66.0 | 3.95e-01 | 83.0% | 13.8% |
| 3988856 | 4146.1.1.1 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like › YqgQ-like | 0.85 | 63.0 | 5.58e-01 | 79.2% | 58.1% |
| 4000005 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.84 | 76.0 | 6.81e-01 | 96.2% | 80.0% |
| 4175809 | 5086.1.1.88 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD | 0.84 | 66.0 | 4.55e-01 | 84.9% | 29.7% |
| 3944501 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 68.0 | 5.82e-01 | 86.8% | 60.0% |
| 3972622 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 67.0 | 5.35e-01 | 86.8% | 48.0% |
| 4971062 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.83 | 67.0 | 5.63e-01 | 86.8% | 56.5% |
| 3936611 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.83 | 73.0 | 6.30e-01 | 96.2% | 70.0% |
| 3974573 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.83 | 67.0 | 4.91e-01 | 86.8% | 36.9% |
| None | — | 0.82 | 66.0 | 4.86e-01 | 86.8% | 36.9% | |
| 156884 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.82 | 66.0 | 3.84e-01 | 86.8% | 11.7% |
| 4525341 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 65.0 | 5.95e-01 | 86.8% | 71.4% |
| 3974625 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.82 | 66.0 | 5.98e-01 | 86.8% | 68.6% |
| 4174593 | 3922.1.1.248 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF25876 | 0.82 | 64.0 | 5.71e-01 | 84.9% | 62.7% |
| 3971349 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.82 | 65.0 | 6.29e-01 | 86.8% | 80.0% |
| 3486312 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.82 | 64.0 | 4.86e-01 | 84.9% | 39.5% |
| 3973636 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 65.0 | 5.78e-01 | 86.8% | 66.7% |
| 3941960 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.81 | 65.0 | 4.86e-01 | 86.8% | 38.4% |
| 3838083 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.81 | 67.0 | 6.10e-01 | 90.6% | 72.9% |
| 3323850 | 601.1.1.58 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FPP | 0.81 | 72.0 | 6.30e-01 | 96.2% | 68.0% |
| 3981585 | 5086.1.1.84 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND | 0.80 | 64.0 | 5.71e-01 | 86.8% | 66.7% |
| 5046133 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.80 | 71.0 | 5.86e-01 | 96.2% | 75.6% |
| 4046042 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 67.0 | 5.01e-01 | 90.6% | 40.8% |
| 3473827 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 65.0 | 6.24e-01 | 86.8% | 76.7% |
| 2636640 | 192.15.1.3 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core | 0.80 | 67.0 | 5.85e-01 | 90.6% | 66.2% |
| 4036645 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.80 | 63.0 | 4.25e-01 | 86.8% | 24.6% |
| 3978264 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.78 | 60.0 | 4.35e-01 | 84.9% | 32.7% |
| 3737309 | 509.1.1.1 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH | 0.78 | 59.0 | 5.53e-01 | 86.8% | 66.2% |
| 3982740 | 5086.1.1.190 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › OEP | 0.78 | 60.0 | 4.02e-01 | 84.9% | 23.5% |
| 4220406 | 375.1.9.14 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › GvpG | 0.77 | 61.0 | 5.61e-01 | 86.8% | 69.1% |
| 3975632 | 5086.1.1.92 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE | 0.76 | 60.0 | 4.09e-01 | 86.8% | 27.0% |
| 3355246 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.75 | 61.0 | 5.33e-01 | 90.6% | 63.7% |
| 3491875 | 4146.1.1.0 ↗ | alpha bundles › YqgQ-like › YqgQ-like › YqgQ-like | 0.73 | 56.0 | 5.45e-01 | 84.9% | 75.0% |
| 2831866 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.69 | 52.0 | 4.10e-01 | 84.9% | 38.8% |
| 3471267 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.69 | 59.0 | 3.43e-01 | 100.0% | 41.4% |
| 3281235 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.68 | 53.0 | 4.77e-01 | 86.8% | 65.3% |
| 5030164 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.64 | 52.0 | 4.75e-01 | 90.6% | 88.6% |