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CAKLQF020000001.1__CAH1069635.1__SAMEA5780031_00072__00069
Bact-VirCAKLQF020000001.1__CAH1069635.1__SAMEA5780031_00072__00069
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 19-46_95-166
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 46.0 | 4.00e-01 | 83.0% | 81.9% |
| 3h0dB02 | 1.10.1200.150 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain | 0.58 | 36.0 | 3.97e-01 | 99.0% | 77.8% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 38.0 | 3.49e-01 | 70.0% | 63.2% |
| 2raeA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 41.0 | 3.75e-01 | 80.0% | 89.1% |
| 2eh3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 42.0 | 3.95e-01 | 83.0% | 88.5% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 40.0 | 3.56e-01 | 82.0% | 81.9% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.53 | 33.0 | 3.21e-01 | 77.0% | 55.6% |
| 3aqlA02 | 1.10.3090.10 | Mainly Alpha › Orthogonal Bundle › cca-adding enzyme, domain 2 › cca-adding enzyme, domain 2 | 0.52 | 39.0 | 2.97e-01 | 81.0% | 49.2% |
| 1f20A01 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.50 | 38.0 | 3.25e-01 | 80.0% | 83.4% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5063775 | 5051.1.1.3 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF | 0.88 | 82.0 | 5.09e-01 | 100.0% | 30.7% |
| 2448172 | 5051.1.1.7 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Nramp | 0.74 | 67.0 | 5.43e-01 | 100.0% | 77.9% |
| 3266945 | 103.12.1.0 ↗ | alpha arrays › RuvA-C › ANTAR domain › ANTAR domain | 0.66 | 33.0 | 3.97e-01 | 72.0% | 72.3% |
| 3700443 | 101.1.1.176 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DEK_C | 0.65 | 32.0 | 3.83e-01 | 79.0% | 70.8% |
| 5060042 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.63 | 32.0 | 2.89e-01 | 100.0% | 34.3% |
| 3423943 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.60 | 40.0 | 4.38e-01 | 97.0% | 85.0% |
| 5056276 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.59 | 44.0 | 3.71e-01 | 77.0% | 90.0% |
| 4048893 | 101.17.1.1 ↗ | alpha arrays › HTH › IHF-like DNA-binding proteins › IHF-like DNA-binding proteins › Bac_DNA_binding | 0.59 | 40.0 | 4.74e-01 | 84.0% | 100.0% |
| 3962973 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 46.0 | 4.26e-01 | 88.0% | 91.1% |
| 5078792 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.51 | 43.0 | 4.20e-01 | 93.0% | 87.3% |
| 5081529 | 3931.1.1.0 ↗ | alpha bundles › MtlR-like › MtlR-like › MtlR-like | 0.50 | 44.0 | 4.00e-01 | 98.0% | 86.7% |
D2
medium
residues 47-94_203-268_338-386
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.63 | 42.0 | 4.32e-01 | 100.0% | 69.4% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.59 | 32.0 | 3.03e-01 | 87.1% | 41.4% |
| 2ew2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.59 | 33.0 | 3.61e-01 | 100.0% | 64.9% |
| 2k0nA00 | 1.10.246.20 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain | 0.58 | 29.0 | 3.84e-01 | 88.3% | 88.2% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.58 | 23.0 | 3.16e-01 | 79.8% | 69.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.58 | 42.0 | 3.82e-01 | 100.0% | 55.3% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 33.0 | 4.04e-01 | 99.4% | 89.0% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 46.0 | 3.83e-01 | 100.0% | 49.1% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 46.0 | 3.85e-01 | 100.0% | 50.7% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 33.0 | 3.75e-01 | 89.6% | 82.5% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.52 | 38.0 | 4.26e-01 | 84.0% | 99.2% |
| 5zbqA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 42.0 | 3.52e-01 | 100.0% | 48.6% |
| 7lb8B01 | 1.10.3470.10 | Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC | 0.52 | 39.0 | 3.11e-01 | 77.9% | 88.0% |
| 1tjoB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 33.0 | 3.29e-01 | 100.0% | 61.1% |
| 1w27A02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.51 | 45.0 | 3.64e-01 | 99.4% | 94.3% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3787648 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.78 | 73.0 | 5.03e-01 | 100.0% | 78.2% |
| 3468199 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.65 | 52.0 | 4.02e-01 | 84.7% | 74.7% |
| 4979163 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.61 | 29.0 | 3.06e-01 | 75.5% | 47.7% |
| 3294544 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.57 | 44.0 | 3.95e-01 | 80.4% | 86.1% |
| 3726746 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.57 | 37.0 | 3.87e-01 | 92.0% | 71.7% |
| 3860471 | 150.1.1.31 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety | 0.56 | 44.0 | 3.99e-01 | 100.0% | 60.5% |
| 3220482 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 44.0 | 3.50e-01 | 100.0% | 38.9% |
| 3427954 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.56 | 37.0 | 4.01e-01 | 93.3% | 78.6% |
| 5044068 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.55 | 30.0 | 3.87e-01 | 96.9% | 90.5% |
| 3312652 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.55 | 40.0 | 4.14e-01 | 100.0% | 82.0% |
| 3805395 | 3291.1.1.119 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › NET2A | 0.54 | 47.0 | 4.30e-01 | 92.0% | 78.6% |
| 3464011 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.54 | 41.0 | 3.11e-01 | 80.4% | 64.7% |
| 3446919 | 611.7.1.15 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Rx_N | 0.54 | 35.0 | 3.73e-01 | 92.0% | 75.0% |
| 3420977 | 3755.4.1.17 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Rx_N | 0.53 | 34.0 | 3.55e-01 | 91.4% | 69.3% |
| 3975940 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.52 | 37.0 | 3.87e-01 | 100.0% | 78.0% |
| 4023330 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.52 | 39.0 | 3.81e-01 | 100.0% | 70.9% |
| 3230238 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 35.0 | 3.47e-01 | 100.0% | 63.5% |
| 3486439 | 1188.1.1.0 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter | 0.51 | 35.0 | 3.39e-01 | 100.0% | 60.3% |
| 4202056 | 129.1.1.11 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › ApbA_C | 0.51 | 30.0 | 3.37e-01 | 99.4% | 74.2% |
| 3774709 | 150.1.1.31 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety | 0.51 | 46.0 | 3.76e-01 | 100.0% | 56.1% |
| 5050751 | 3565.1.1.1 ↗ | alpha bundles › Na/H pumping membrane integral pyrophosphatase › Na/H pumping membrane integral pyrophosphatase › Na/H pumping membrane integral pyrophosphatase › H_PPase | 0.50 | 46.0 | 3.04e-01 | 100.0% | 77.3% |
D3
medium
residues 167-202_269-337_387-404
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 31.0 | 3.79e-01 | 79.7% | 73.5% |
| 1e7pC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.57 | 39.0 | 3.12e-01 | 70.7% | 61.0% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.52 | 33.0 | 3.57e-01 | 73.2% | 74.5% |