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CAKLQF020000001.1__CAH1069645.1__SAMEA5780031_00077__00074

Bact-Vir

CAKLQF020000001.1__CAH1069645.1__SAMEA5780031_00077__00074

Identity

Kingdom:
phage

Quality

92.7 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 11-201
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00654.26 best Voltage_CLC 100.6 1.40e-28 73.8% 40.5%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kplA00 1.10.3080.10 Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel 0.89 84.0 6.22e-01 98.4% 47.0%
3orgA01 1.10.3080.10 Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel 0.88 84.0 6.35e-01 99.5% 51.0%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.64 32.0 3.46e-01 93.7% 55.9%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.59 29.0 3.43e-01 89.5% 65.6%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 29.0 3.08e-01 91.1% 52.0%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.56 41.0 3.97e-01 74.3% 69.6%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.55 26.0 3.18e-01 85.3% 66.9%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.55 31.0 2.90e-01 92.7% 45.8%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 31.0 3.01e-01 92.1% 49.3%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.53 42.0 3.29e-01 82.7% 95.5%
1pw4A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 42.0 4.11e-01 99.5% 75.5%
4bwcA02 1.10.439.20 Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Phospholipase B-like, domain 2 0.53 25.0 3.17e-01 72.8% 71.8%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.53 37.0 4.01e-01 80.1% 87.0%
1xwmA00 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 36.0 3.47e-01 70.2% 67.0%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 39.0 4.01e-01 83.2% 84.8%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 41.0 4.10e-01 99.5% 81.8%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 38.0 3.93e-01 94.8% 80.7%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.50 39.0 4.06e-01 99.5% 86.4%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4253816 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.97 95.0 7.00e-01 100.0% 45.3%
2389152 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.93 91.0 6.83e-01 100.0% 48.2%
3957999 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.92 89.0 6.89e-01 99.0% 58.6%
4948538 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.92 80.0 6.04e-01 92.1% 43.3%
5055240 3470.1.1.54 extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Voltage_CLC 0.92 89.0 8.02e-01 100.0% 81.6%
4991030 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.92 89.0 6.66e-01 100.0% 46.7%
3588236 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.52e-01 100.0% 46.7%
4954615 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.49e-01 100.0% 46.9%
4946170 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.47e-01 100.0% 43.9%
4943779 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.43e-01 100.0% 46.1%
5059665 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 87.0 6.53e-01 99.5% 48.4%
5021493 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.54e-01 100.0% 47.6%
5014511 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 88.0 6.45e-01 100.0% 46.7%
4976380 5053.1.1.0 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel 0.91 87.0 6.43e-01 100.0% 45.7%
5045280 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.90 87.0 6.35e-01 100.0% 44.0%
5044315 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.90 87.0 6.53e-01 100.0% 46.8%
4975275 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.90 87.0 6.36e-01 100.0% 45.0%
5073313 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.90 83.0 6.14e-01 95.8% 45.6%
5077029 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.89 86.0 6.33e-01 100.0% 47.3%
5059368 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.89 86.0 6.29e-01 100.0% 45.7%
151125 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.88 85.0 6.24e-01 100.0% 46.4%
3798261 5053.1.1.0 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel 0.88 84.0 6.02e-01 100.0% 44.2%
3943918 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.87 84.0 6.30e-01 100.0% 50.8%
3597869 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.87 83.0 6.04e-01 99.0% 42.9%
4022827 5053.1.1.0 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel 0.87 83.0 5.85e-01 100.0% 48.3%
3634253 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.87 83.0 5.84e-01 100.0% 45.4%
4207973 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.86 80.0 5.94e-01 95.8% 47.1%
4973594 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.85 80.0 6.06e-01 99.0% 47.0%
3461149 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.83 78.0 5.76e-01 98.4% 46.1%
5052608 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 32.0 3.29e-01 95.8% 45.4%
3733697 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.65 32.0 2.37e-01 93.7% 19.8%
3732518 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 45.0 4.16e-01 100.0% 65.5%
4949583 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.54 40.0 4.01e-01 94.8% 75.3%
3612202 5073.1.1.11 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C 0.54 40.0 3.04e-01 75.4% 73.8%
4995211 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 41.0 4.07e-01 99.0% 75.5%
3653751 5058.1.1.11 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › TerC 0.53 40.0 3.72e-01 99.5% 64.3%
1407186 3832.1.1.1 alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 0.52 37.0 3.74e-01 81.7% 72.0%
3973008 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.52 36.0 3.66e-01 70.2% 73.2%
5009658 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 40.0 3.99e-01 100.0% 77.4%
D2 high residues 246-393
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00654.26 best Voltage_CLC 84.7 1.00e-23 100.0% 43.1%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kplA00 1.10.3080.10 Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel 0.89 85.0 5.89e-01 100.0% 37.7%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.60 44.0 4.69e-01 82.4% 86.0%
2hr2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 42.0 4.21e-01 80.4% 94.9%
1elrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 37.0 3.93e-01 78.4% 78.9%
3rkvA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 39.0 4.01e-01 76.4% 88.4%
3gw4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 38.0 3.52e-01 73.6% 74.0%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 34.0 3.18e-01 75.0% 51.9%
5fzsA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 33.0 3.69e-01 79.7% 85.0%
4ga0A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 34.0 3.50e-01 98.6% 68.5%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4253816 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.99 97.0 6.60e-01 100.0% 36.3%
2389152 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.97 95.0 6.59e-01 100.0% 37.6%
4991030 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.92 89.0 6.19e-01 100.0% 40.1%
3602966 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.92 88.0 6.21e-01 100.0% 38.0%
4948538 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.91 87.0 6.15e-01 100.0% 41.0%
3599919 5053.1.1.0 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel 0.88 84.0 5.49e-01 100.0% 40.9%
5044315 5053.1.1.1 alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC 0.88 83.0 5.85e-01 100.0% 38.0%
3890914 109.4.1.2043 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10, TPR_16 0.56 36.0 3.92e-01 82.4% 76.8%
4193126 109.4.1.1841 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10, TPR_11 0.55 38.0 3.74e-01 82.4% 65.2%
4518882 109.4.1.1394 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_12 0.55 39.0 3.93e-01 73.0% 73.1%
3341921 109.4.1.1441 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_11, TPR_16 0.54 35.0 3.62e-01 76.4% 69.6%
4067921 109.4.1.95 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2 0.54 40.0 3.85e-01 86.5% 67.1%
3683792 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 36.0 4.02e-01 76.4% 90.9%
5036565 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.53 43.0 4.08e-01 89.9% 80.0%
3414246 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 43.0 4.41e-01 87.2% 95.7%
None 0.52 35.0 3.69e-01 82.4% 73.9%
3253567 109.4.1.1453 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_17 0.52 40.0 3.98e-01 89.2% 76.8%
4996493 109.4.1.5 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1 0.52 35.0 3.69e-01 82.4% 76.2%
3855257 109.4.1.1473 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11, TPR_12 0.51 37.0 3.65e-01 73.6% 75.5%
None 0.51 40.0 3.86e-01 89.2% 72.9%
4958131 109.10.1.0 alpha superhelices › Repetitive alpha hairpins › Translin › Translin 0.51 43.0 3.88e-01 92.6% 73.7%