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CAKLQF020000001.1__CAH1069711.1__SAMEA5780031_00112__00107

Bact-Vir

CAKLQF020000001.1__CAH1069711.1__SAMEA5780031_00112__00107

Identity

Kingdom:
phage

Quality

86.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-81
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05947.18 best T6SS_TssF 95.3 4.90e-27 100.0% 13.3%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.72 48.0 4.72e-01 81.5% 64.7%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 44.0 4.61e-01 79.0% 69.3%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 46.0 4.68e-01 84.0% 71.8%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.65 50.0 4.11e-01 98.8% 44.4%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 43.0 4.83e-01 84.0% 87.3%
5f1cA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.63 44.0 5.02e-01 84.0% 98.3%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.63 42.0 3.81e-01 76.5% 50.9%
6qv3A05 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 40.0 3.82e-01 91.4% 58.1%
2y1eA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.60 38.0 3.72e-01 77.8% 57.5%
2bskB00 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.60 42.0 4.60e-01 90.1% 92.3%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.59 44.0 3.66e-01 79.0% 68.1%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 47.0 4.38e-01 86.4% 82.5%
4kjmA02 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.59 34.0 3.92e-01 76.5% 81.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 43.0 3.74e-01 76.5% 82.2%
2x1dA02 1.10.10.2120 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.58 39.0 4.08e-01 70.4% 74.3%
2wl8C00 1.20.120.900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain 0.58 40.0 3.69e-01 71.6% 90.8%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 40.0 3.43e-01 74.1% 42.6%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 43.0 3.29e-01 81.5% 93.1%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.56 37.0 4.01e-01 74.1% 82.4%
1ezvC00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.55 47.0 3.15e-01 100.0% 47.3%
7jpxA02 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.55 42.0 3.68e-01 81.5% 82.6%
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 42.0 3.55e-01 100.0% 47.3%
1v9mA03 1.20.1690.10 Mainly Alpha › Up-down Bundle › V-type ATP synthase subunit C fold › V-type ATP synthase subunit C domain 0.54 39.0 3.72e-01 76.5% 97.9%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 42.0 3.04e-01 91.4% 29.2%
2yqrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.53 39.0 3.65e-01 79.0% 94.2%
2qksA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 43.0 3.98e-01 90.1% 85.8%
3akjA02 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.50 38.0 2.86e-01 80.2% 75.6%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4145392 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.72 45.0 3.24e-01 81.5% 23.7%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 46.0 4.53e-01 82.7% 65.9%
3282043 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.65 47.0 4.71e-01 87.7% 72.9%
3910567 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 46.0 3.76e-01 86.4% 40.0%
None 0.64 42.0 2.96e-01 85.2% 21.6%
5019837 2003.1.1.24 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH 0.64 42.0 2.96e-01 85.2% 21.6%
3588971 6026.1.1.0 alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.63 45.0 4.63e-01 88.9% 80.0%
3233589 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.62 42.0 4.37e-01 79.0% 74.7%
3733140 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 47.0 3.84e-01 92.6% 42.6%
3778785 4325.1.1.8 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › Strabismus 0.62 41.0 3.64e-01 74.1% 46.7%
5033071 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.61 43.0 4.00e-01 72.8% 81.0%
3605868 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.61 38.0 3.45e-01 80.2% 46.4%
4955252 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.60 42.0 3.93e-01 72.8% 75.0%
3888542 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.60 48.0 3.59e-01 87.7% 42.9%
4610324 5056.1.1.1 extended segments › Gated mechanosensitive channel › Gated mechanosensitive channel › Gated mechanosensitive channel › MscL 0.60 53.0 4.64e-01 100.0% 66.4%
3685214 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.58 46.0 4.54e-01 85.2% 80.0%
3215465 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.58 45.0 3.82e-01 85.2% 51.5%
4127216 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.57 43.0 3.87e-01 81.5% 70.4%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 48.0 4.52e-01 93.8% 86.0%
4033102 632.5.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylocoagulase › Staphylocoagulase 0.56 45.0 4.24e-01 85.2% 92.6%
3971610 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.56 47.0 3.49e-01 95.1% 77.7%
3756471 633.24.1.4 alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › RIN1 0.55 39.0 3.48e-01 72.8% 52.2%
4590703 5050.1.1.54 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp 0.55 43.0 3.29e-01 95.1% 35.9%
5029809 4095.1.1.1 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N 0.54 43.0 3.05e-01 86.4% 82.0%
4625812 2006.1.4.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_5 0.53 46.0 3.31e-01 96.3% 40.8%
3957096 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.53 43.0 3.32e-01 87.7% 66.5%
5020872 1079.1.1.1 alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD 0.53 43.0 3.23e-01 88.9% 68.3%
3584894 605.1.1.238 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › CNNM 0.53 42.0 4.08e-01 88.9% 77.8%
3292571 3861.1.1.1 alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR 0.53 42.0 3.45e-01 88.9% 47.5%
D2 high residues 141-310
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05947.18 best T6SS_TssF 75.5 4.90e-21 98.2% 26.5%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 26.0 3.45e-01 92.4% 75.6%
4hsqA01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 43.0 4.60e-01 98.8% 91.7%
3uxfA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 4.73e-01 100.0% 89.8%
4lowA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.56 29.0 3.89e-01 95.9% 98.8%
2cz4A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 27.0 3.44e-01 87.1% 76.8%
1q5yC00 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.55 25.0 3.46e-01 91.2% 85.4%
1fu0A00 3.30.1340.10 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › HPr-like 0.55 30.0 3.86e-01 87.1% 98.9%
5suhB01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.55 31.0 3.82e-01 97.1% 91.9%
4igbB02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 40.0 4.33e-01 98.8% 90.2%
3hr6A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 43.0 4.49e-01 100.0% 91.7%
2pgcA02 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 30.0 3.63e-01 77.6% 84.0%
4zmuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.54 31.0 3.27e-01 92.4% 61.3%
1jelP00 3.30.1340.10 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › HPr-like 0.53 29.0 3.75e-01 87.1% 100.0%
1q8mA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 33.0 3.80e-01 92.9% 86.8%
2m88A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 24.0 3.18e-01 76.5% 79.1%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 23.0 3.33e-01 90.0% 90.5%
3tj8A02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.52 23.0 3.13e-01 77.1% 83.8%
2zbvC02 2.40.30.90 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Bacterial fluorinating enzyme like 0.52 32.0 3.88e-01 83.5% 99.0%
3ahpA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 28.0 3.40e-01 78.2% 82.1%
4ofqA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 41.0 4.29e-01 98.8% 93.5%
1b9hA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 36.0 3.89e-01 91.8% 87.8%
4oi3A00 3.30.70.3090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer 0.51 25.0 3.28e-01 76.5% 91.4%
2x9zA01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 40.0 4.26e-01 100.0% 96.0%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3949363 12.1.1.99 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › T6SS_TssF 0.84 63.0 7.15e-01 97.1% 100.0%
3709157 10.41.1.1 beta sandwiches › jelly-roll › Protein Hikeshi jelly-roll domain › Protein Hikeshi jelly-roll domain › Hikeshi-like_N 0.63 35.0 4.00e-01 85.3% 71.2%
3876448 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.61 37.0 3.99e-01 75.9% 71.4%
4963450 304.4.1.1 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.60 28.0 3.55e-01 77.1% 73.5%
5021743 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 36.0 4.37e-01 91.8% 95.2%
3945048 322.1.1.1 a+b two layers › HPr-like › HPr-like › HPr-like › PTS-HPr 0.56 29.0 3.96e-01 86.5% 97.6%
4025812 304.110.1.1 a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › Acylphosphatase 0.56 28.0 3.48e-01 77.6% 76.0%
3230123 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.55 28.0 3.32e-01 92.4% 67.8%
3590065 11.1.5.50 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › AgI_II_C2 0.55 42.0 4.49e-01 98.8% 91.3%
1150288 304.54.1.1 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like › BMC 0.54 34.0 4.04e-01 98.8% 93.0%
1070070 11.1.5.52 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Sgo0707_N2 0.54 40.0 4.28e-01 98.8% 87.8%
3588312 322.1.1.1 a+b two layers › HPr-like › HPr-like › HPr-like › PTS-HPr 0.54 29.0 3.76e-01 87.1% 96.6%
3175337 1.1.7.24 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.54 32.0 3.90e-01 98.2% 96.0%
4568147 322.1.1.1 a+b two layers › HPr-like › HPr-like › HPr-like › PTS-HPr 0.53 29.0 3.77e-01 88.8% 98.9%
5028338 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.53 26.0 3.29e-01 77.6% 77.0%
3396189 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 35.0 3.89e-01 94.7% 85.2%
3275065 10.32.1.76 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › BetaGal_gal-bd 0.52 45.0 4.62e-01 98.8% 97.5%
4103307 322.1.1.1 a+b two layers › HPr-like › HPr-like › HPr-like › PTS-HPr 0.52 28.0 3.69e-01 87.6% 100.0%
4985071 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.52 29.0 3.65e-01 78.8% 92.9%
868875 304.54.1.1 a+b two layers › Alpha-beta plaits › CcmK-like › CcmK-like › BMC 0.51 35.0 3.91e-01 100.0% 89.6%
224104 3016.1.1.6 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › DegT_DnrJ_EryC1 0.50 35.0 3.90e-01 91.8% 90.4%
D3 high residues 314-425
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05947.18 best T6SS_TssF 42.5 4.90e-11 100.0% 18.9%
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4igbB02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.65 49.0 4.49e-01 100.0% 62.2%
3ne5C02 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.63 52.0 5.41e-01 100.0% 96.1%
2vo8A00 2.60.40.680 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 44.0 4.17e-01 100.0% 60.7%
5utkA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 40.0 4.31e-01 97.3% 85.6%
6sl4A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.58 47.0 4.30e-01 98.2% 65.3%
1f15B00 2.60.120.530 Mainly Beta › Sandwich › Jelly Rolls › Cucumovirus coat protein, subunit A 0.57 52.0 4.34e-01 100.0% 74.7%
2ed6A01 2.60.40.2770 Mainly Beta › Sandwich › Immunoglobulin-like › WSSV envelope protein-like 0.56 50.0 4.56e-01 100.0% 97.4%
1stmA00 2.60.120.220 Mainly Beta › Sandwich › Jelly Rolls › Satellite virus coat domain 0.56 51.0 4.73e-01 100.0% 92.9%
3cjiA00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.56 50.0 3.87e-01 100.0% 82.6%
2m83A00 2.60.40.2440 Mainly Beta › Sandwich › Immunoglobulin-like › Carbohydrate binding type-21 domain 0.56 42.0 3.96e-01 96.4% 64.7%
4b96A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.56 44.0 4.05e-01 98.2% 63.6%
3lsoA03 2.60.40.2260 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 4.09e-01 100.0% 63.3%
1cwpA00 2.60.120.220 Mainly Beta › Sandwich › Jelly Rolls › Satellite virus coat domain 0.56 50.0 4.57e-01 100.0% 87.2%
6grsA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 38.0 4.06e-01 93.8% 83.2%
4b97A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.55 45.0 4.16e-01 100.0% 66.9%
5u8rA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 41.0 4.19e-01 97.3% 82.4%
2dliA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 38.0 4.06e-01 95.5% 82.7%
4rs5A00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.54 48.0 3.90e-01 100.0% 79.6%
3kt4A02 3.60.130.20 Alpha Beta › 4-Layer Sandwich › Double-stranded beta-helix › Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain 0.53 40.0 2.95e-01 80.4% 77.5%
4eeeA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 40.0 4.07e-01 95.5% 80.9%
2fbjH02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 33.0 3.87e-01 83.0% 95.9%
1e57B00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.53 46.0 4.00e-01 100.0% 82.5%
1g43A00 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.52 45.0 4.06e-01 100.0% 68.1%
1n08A00 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.52 42.0 3.85e-01 99.1% 64.9%
3ptyA02 2.60.120.940 Mainly Beta › Sandwich › Jelly Rolls › EmbC, C-terminal domain, subdomain 2 0.52 43.0 3.77e-01 100.0% 58.4%
4rdlA02 2.40.30.120 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses 0.52 43.0 4.40e-01 96.4% 97.2%
2mizA00 2.60.40.2900 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 45.0 4.11e-01 100.0% 81.4%
1y7eA02 2.30.250.10 Mainly Beta › Roll › Aminopeptidase i, Domain 2 › Aminopeptidase i, Domain 2 0.52 43.0 4.30e-01 94.6% 99.2%
3vx8A01 3.40.140.100 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain 0.52 37.0 3.50e-01 75.9% 83.0%
7ylrA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.52 44.0 4.52e-01 95.5% 99.0%
2eixA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.52 43.0 4.41e-01 96.4% 97.2%
3o3uN03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 41.0 4.11e-01 96.4% 86.5%
4gafB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 41.0 4.13e-01 99.1% 89.1%
5mqcB00 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.51 45.0 3.63e-01 100.0% 71.4%
2zgoA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 46.0 3.99e-01 98.2% 94.6%
3bnwB00 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.51 44.0 4.03e-01 99.1% 97.5%
4dzgA00 2.60.120.380 Mainly Beta › Sandwich › Jelly Rolls › 0.50 41.0 4.17e-01 100.0% 89.4%
4kq7A02 2.60.120.1390 Mainly Beta › Sandwich › Jelly Rolls › Protein of unknown function DUF2961 0.50 44.0 3.64e-01 100.0% 80.1%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3945562 1.1.7.111 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › T6SS_TssF 0.77 72.0 7.12e-01 98.2% 95.7%
3832688 4081.1.1.7 beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Ribophorin_I 0.62 49.0 4.05e-01 100.0% 46.8%
3543937 11.1.1.297 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Integrin_A_Ig_2 0.61 45.0 4.16e-01 100.0% 60.0%
4299010 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.59 46.0 4.93e-01 100.0% 98.9%
3396112 10.32.1.235 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › MBF2 0.58 43.0 4.56e-01 100.0% 88.0%
4948087 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 50.0 4.77e-01 97.3% 83.8%
5055944 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.57 39.0 3.95e-01 99.1% 71.8%
3337313 1.1.7.10 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.57 42.0 4.09e-01 100.0% 70.4%
3926311 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 39.0 3.94e-01 99.1% 71.8%
3733710 10.12.1.107 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › PF27522 0.56 42.0 3.24e-01 80.4% 69.6%
3314257 10.32.1.193 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › MP 0.55 49.0 4.29e-01 100.0% 85.1%
1066946 11.1.5.8 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › CBM_3 0.55 47.0 4.16e-01 100.0% 62.9%
4864011 1.1.7.41 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › UPF1_1B_dom 0.55 43.0 4.47e-01 98.2% 92.4%
4026425 1.1.7.10 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.55 44.0 4.08e-01 100.0% 67.6%
3967057 10.12.1.107 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › PF27522 0.54 42.0 3.23e-01 82.1% 71.5%
3929255 1.1.7.10 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.54 44.0 4.09e-01 100.0% 69.0%
3264337 12.3.1.0 beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.54 49.0 3.75e-01 100.0% 57.3%
3284021 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.54 46.0 4.66e-01 97.3% 95.5%
3267027 12.5.1.0 beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related 0.54 47.0 3.98e-01 97.3% 63.7%
3731316 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.53 44.0 4.44e-01 98.2% 90.9%
3703044 1.1.7.10 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.53 46.0 4.07e-01 99.1% 65.5%
3174670 1.1.7.10 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.53 47.0 3.99e-01 100.0% 70.7%
3932246 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 43.0 4.29e-01 95.5% 87.0%
3879276 11.1.1.99 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set 0.53 46.0 4.36e-01 100.0% 82.2%
3592708 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.52 46.0 4.15e-01 100.0% 73.8%
3701894 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.52 43.0 4.16e-01 98.2% 82.4%
3612035 10.2.1.55 beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › NPL 0.52 44.0 4.52e-01 100.0% 96.4%
4567712 10.32.1.48 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › CBM_26 0.52 46.0 4.47e-01 100.0% 96.0%
3535347 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.52 44.0 4.45e-01 96.4% 99.1%
4283995 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.52 45.0 4.02e-01 99.1% 84.2%
3688095 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.51 43.0 4.25e-01 94.6% 99.2%
3356728 1.1.7.55 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › DUF6469 0.50 42.0 4.23e-01 92.9% 93.9%
D4 high residues 468-596
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05947.18 best T6SS_TssF 94.5 9.00e-27 100.0% 20.4%
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hlbA00 3.30.70.2960 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.73 51.0 5.92e-01 87.6% 97.9%
1yj7D02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.73 45.0 5.34e-01 85.3% 90.8%
5o5jC01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.72 43.0 5.06e-01 81.4% 85.6%
6he0A01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.71 45.0 4.88e-01 82.9% 76.6%
6nqbC01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.69 42.0 4.86e-01 81.4% 84.6%
3ib5A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.69 49.0 3.56e-01 89.9% 27.8%
4bpeC01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.68 43.0 4.92e-01 80.6% 87.0%
3bypA00 3.30.70.1350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain 0.68 43.0 5.14e-01 81.4% 97.6%
3npdA00 3.30.300.250 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.68 48.0 5.11e-01 89.1% 82.3%
3n2qA02 3.30.300.190 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.68 47.0 4.98e-01 89.9% 79.3%
4r0mA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.65 42.0 4.50e-01 82.9% 75.9%
4ls9B02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.65 42.0 4.29e-01 73.6% 66.7%
4hn3A00 3.10.570.10 Alpha Beta › Roll › sex pheromone staph- cam373 precursor fold › sex pheromone staph- cam373 precursor domain 0.65 54.0 3.96e-01 88.4% 42.8%
3ajvC02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.65 36.0 4.14e-01 86.0% 74.7%
4oycB00 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.64 40.0 4.63e-01 79.8% 89.9%
4l4qA02 3.30.300.340 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › S-adenosylmethionine synthetase, N-terminal domain 0.63 48.0 4.85e-01 82.9% 80.3%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 39.0 4.26e-01 82.9% 76.5%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 38.0 4.24e-01 82.9% 77.2%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 38.0 4.12e-01 82.9% 72.9%
3kxwA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.60 49.0 5.06e-01 88.4% 91.1%
4l4qA03 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.60 46.0 4.73e-01 82.2% 88.8%
3devA02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.60 34.0 3.56e-01 82.2% 60.3%
3ngqA00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.60 49.0 3.65e-01 89.1% 49.6%
2dhmA01 3.30.300.90 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like 0.59 40.0 4.58e-01 84.5% 97.8%
2onfA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.59 43.0 4.29e-01 80.6% 73.1%
4mh4A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.59 41.0 4.62e-01 78.3% 97.9%
4ywzB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 31.0 3.02e-01 89.1% 43.2%
2bjoA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.58 41.0 4.56e-01 79.1% 98.9%
1gpmA03 3.30.300.10 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.58 43.0 4.64e-01 82.9% 93.5%
7r7eA01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.57 46.0 4.80e-01 87.6% 93.3%
1darA04 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.57 37.0 3.90e-01 80.6% 71.4%
4i43B04 3.90.1570.40 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › Pre-mRNA-processing-splicing factor 8 (Prp8), endonuclease domain 0.57 45.0 4.06e-01 86.8% 62.2%
2qb7B02 3.10.310.20 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain 0.57 38.0 3.71e-01 79.1% 61.4%
3ks7A02 2.60.120.230 Mainly Beta › Sandwich › Jelly Rolls › 0.55 30.0 2.74e-01 96.1% 37.4%
3n54B03 3.30.300.210 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Nutrient germinant receptor protein C, domain 3 0.54 43.0 4.20e-01 86.0% 99.3%
3m7vA02 3.30.70.1250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phosphopentomutase 0.54 44.0 4.60e-01 89.9% 98.3%
4gl6A02 3.10.310.80 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Domain of unknown function (DUF5037), C-terminal subdomain 0.53 42.0 3.96e-01 82.9% 87.0%
2d7vB00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.53 42.0 4.02e-01 83.7% 100.0%
2gw6A01 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.52 40.0 4.24e-01 94.6% 90.5%
2ql8A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.52 42.0 4.16e-01 88.4% 95.0%
3l0aA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.52 46.0 3.67e-01 99.2% 76.7%
2x7bA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.52 41.0 3.91e-01 86.8% 78.8%
2e8eA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.51 43.0 4.29e-01 89.9% 99.2%
3dnsA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 43.0 4.37e-01 93.8% 96.2%
1iicA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.50 44.0 3.55e-01 95.3% 60.1%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3974303 4081.1.1.16 beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › T6SS_TssF 0.91 84.0 8.59e-01 96.9% 100.0%
3981315 327.7.1.16 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › T6SS_TssF 0.90 86.0 7.96e-01 100.0% 84.5%
4112084 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.71 44.0 4.82e-01 81.4% 76.2%
4042773 327.11.1.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › KH_2 0.71 44.0 4.82e-01 81.4% 76.2%
4469157 327.13.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF 0.67 44.0 4.61e-01 82.2% 71.7%
1164102 3535.1.1.1 a+b two layers › Sex pheromone staph-cAM373 › Sex pheromone staph-cAM373 › Sex pheromone staph-cAM373 › CamS 0.67 47.0 4.81e-01 89.9% 74.2%
3712216 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.66 44.0 5.09e-01 85.3% 96.7%
4018954 327.10.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ribosome-binding factor A (RbfA)-related › Ribosome-binding factor A (RbfA)-related 0.66 46.0 4.87e-01 81.4% 80.9%
4223021 327.13.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF 0.65 45.0 4.64e-01 89.1% 72.8%
3262616 327.18.1.0 a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A 0.65 38.0 4.72e-01 82.9% 97.3%
5032710 327.5.1.3 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 0.65 40.0 4.48e-01 83.7% 79.0%
3605286 2008.2.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like 0.65 40.0 4.42e-01 86.0% 78.0%
4386717 327.13.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF 0.65 45.0 4.77e-01 86.8% 80.9%
4433981 327.11.1.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) 0.64 48.0 4.90e-01 82.2% 80.8%
4053920 327.13.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF 0.64 46.0 4.75e-01 87.6% 80.0%
4145589 327.13.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system 0.62 42.0 4.61e-01 81.4% 84.8%
3211449 327.3.1.1 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain › GMP_synt_C 0.62 52.0 4.06e-01 89.9% 92.4%
3716907 327.4.1.0 a+b two layers › Alpha-lytic protease prodomain-like › YhbC-like, N-terminal domain › YhbC-like, N-terminal domain 0.61 42.0 4.72e-01 77.5% 94.7%
4019554 213.1.1.0 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.60 43.0 4.09e-01 86.8% 61.3%
3595866 327.3.1.0 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain 0.60 50.0 4.14e-01 89.9% 90.9%
4405341 2003.1.5.53 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr 0.60 50.0 3.52e-01 91.5% 29.0%
4975902 327.3.1.0 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain 0.59 44.0 4.78e-01 82.9% 95.2%
4947403 327.3.1.1 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain › GMP_synt_C 0.59 48.0 4.46e-01 86.8% 91.2%
3507051 327.3.1.1 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain › GMP_synt_C 0.58 45.0 4.79e-01 82.2% 97.4%
3271300 213.1.1.27 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_7 0.58 45.0 4.09e-01 86.0% 61.1%
3248034 327.3.1.1 a+b two layers › Alpha-lytic protease prodomain-like › GMP synthetase C-terminal dimerisation domain › GMP synthetase C-terminal dimerisation domain › GMP_synt_C 0.58 43.0 3.66e-01 83.7% 46.9%
4884256 2008.1.1.216 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › U6-snRNA_bdg, PRP8_domainIV 0.57 45.0 3.73e-01 86.8% 47.6%
3932877 327.17.1.3 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_M 0.57 43.0 4.52e-01 86.0% 89.6%
4972740 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.57 38.0 4.05e-01 84.5% 78.9%
5005553 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.56 51.0 4.01e-01 100.0% 84.1%
1155793 5104.1.1.3 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 0.56 38.0 3.70e-01 82.2% 61.1%
5024508 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.56 49.0 4.64e-01 95.3% 94.8%
3912477 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.56 42.0 3.19e-01 79.1% 62.2%
4185835 327.13.1.1 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif I in type III secretion system › Ring-building motif I in type III secretion system › YscJ_FliF 0.56 45.0 4.63e-01 94.6% 89.6%
4263042 327.17.1.3 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_M 0.56 45.0 4.58e-01 87.6% 89.6%
3926289 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.55 47.0 3.04e-01 93.8% 91.1%
4101966 327.17.1.3 a+b two layers › Alpha-lytic protease prodomain-like › S-adenosylmethionine synthetase › S-adenosylmethionine synthetase › S-AdoMet_synt_M 0.55 44.0 4.30e-01 84.5% 77.9%
3457392 2008.1.1.97 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Exo5 0.55 50.0 3.84e-01 100.0% 82.4%
4034614 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.54 45.0 4.38e-01 88.4% 99.3%
3954749 304.51.1.2 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › RAMPs 0.54 42.0 3.66e-01 83.7% 93.7%
5071566 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.54 44.0 4.28e-01 86.0% 99.3%
4996818 316.1.1.0 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.54 40.0 3.98e-01 84.5% 74.1%
3693672 131.1.1.27 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › RTG2_C 0.53 45.0 3.73e-01 90.7% 96.4%
5882 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 44.0 4.28e-01 89.1% 85.4%
3691700 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 42.0 4.08e-01 86.0% 95.9%
5879 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 44.0 4.32e-01 89.1% 100.0%
2579238 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 42.0 3.97e-01 84.5% 87.7%
4026764 3105.1.1.4 a+b three layers › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › MOLO1 0.53 43.0 4.02e-01 89.1% 70.0%
5062833 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 41.0 4.07e-01 83.7% 94.3%
5061294 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.53 42.0 4.23e-01 86.0% 87.4%
326556 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.52 43.0 4.34e-01 89.9% 99.2%
324414 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.52 42.0 4.15e-01 89.1% 95.0%
3957089 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.52 25.0 3.37e-01 80.6% 87.1%
4944420 324.1.1.0 a+b two layers › OsmC-like › OsmC-like › OsmC-like 0.51 40.0 3.88e-01 83.7% 94.7%
4228205 324.1.1.1 a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC 0.51 42.0 4.17e-01 92.2% 98.6%
D5 medium residues 88-140_429-463
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05947.18 best T6SS_TssF 40.1 2.60e-10 94.3% 12.8%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ok5A02 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.58 42.0 3.21e-01 78.4% 53.9%
3c5xC00 2.60.260.50 Mainly Beta › Sandwich › HSP40/DNAj peptide-binding domain › Flavivirus polyprotein propeptide domain 0.57 29.0 3.05e-01 73.9% 50.6%
1ifrA00 2.60.40.1260 Mainly Beta › Sandwich › Immunoglobulin-like › Lamin Tail domain 0.56 44.0 4.08e-01 85.2% 82.3%
1w99A02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.51 44.0 3.55e-01 100.0% 52.9%
5bn3A03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.51 29.0 3.30e-01 90.9% 73.8%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3974697 1.16.1.4 beta barrels › cradle loop barrel › Baseplate wedge protein gp6 domain I › Baseplate wedge protein gp6 domain I › T6SS_TssF 0.85 68.0 7.37e-01 96.6% 98.7%
4312599 1.16.1.4 beta barrels › cradle loop barrel › Baseplate wedge protein gp6 domain I › Baseplate wedge protein gp6 domain I › T6SS_TssF 0.83 76.0 7.62e-01 100.0% 96.7%
5004552 1.16.1.0 beta barrels › cradle loop barrel › Baseplate wedge protein gp6 domain I › Baseplate wedge protein gp6 domain I 0.82 70.0 7.31e-01 94.3% 100.0%
5002737 1.16.1.0 beta barrels › cradle loop barrel › Baseplate wedge protein gp6 domain I › Baseplate wedge protein gp6 domain I 0.79 70.0 7.13e-01 100.0% 98.8%
5055242 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 40.0 4.22e-01 94.3% 72.5%
4542557 11.1.1.929 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF28202 0.54 43.0 3.82e-01 89.8% 97.0%