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CAKLQF020000001.1__CAH1070006.1__SAMEA5780031_00250__00243
Bact-VirCAKLQF020000001.1__CAH1070006.1__SAMEA5780031_00250__00243
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 483-536
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2zetC00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.82 | 56.0 | 3.99e-01 | 70.4% | 27.0% |
| 7yuiB01 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.70 | 47.0 | 4.04e-01 | 92.6% | 43.2% |
| 1rfhA01 | 3.30.60.20 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.70 | 49.0 | 5.37e-01 | 94.4% | 100.0% |
| 2xzm500 | 3.30.1740.20 | Alpha Beta › 2-Layer Sandwich › first zn-finger domain of poly(adp-ribose) polymerase-1 › Ribosomal protein S26 | 0.68 | 52.0 | 4.31e-01 | 83.3% | 74.5% |
| 3goxA02 | 3.30.60.130 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.61 | 47.0 | 4.75e-01 | 88.9% | 81.5% |
| 2co8A00 | 2.10.110.10 | Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein | 0.61 | 43.0 | 3.79e-01 | 87.0% | 50.0% |
| 2luyA01 | 3.30.60.210 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Stc1 domain | 0.60 | 45.0 | 4.43e-01 | 79.6% | 98.2% |
| 2xjyA01 | 2.10.110.10 | Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein | 0.60 | 43.0 | 4.17e-01 | 90.7% | 66.7% |
| 1e53A00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.59 | 43.0 | 4.23e-01 | 94.4% | 72.9% |
| 3vkgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.57 | 46.0 | 3.39e-01 | 94.4% | 57.5% |
| 4i0wB01 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.53 | 36.0 | 2.31e-01 | 74.1% | 29.7% |
| 3wknF00 | 6.20.50.120 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.51 | 33.0 | 3.47e-01 | 92.6% | 76.1% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3623406 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.77 | 51.0 | 4.16e-01 | 85.2% | 38.9% |
| 3342185 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.77 | 56.0 | 4.60e-01 | 92.6% | 44.2% |
| 3788517 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.76 | 50.0 | 3.72e-01 | 85.2% | 28.5% |
| 3498231 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.76 | 49.0 | 4.14e-01 | 81.5% | 42.4% |
| 3828987 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.75 | 54.0 | 4.40e-01 | 90.7% | 43.2% |
| 3599588 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.74 | 56.0 | 4.36e-01 | 98.1% | 39.1% |
| 3702126 | 376.1.1.27 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_5 | 0.74 | 48.0 | 4.09e-01 | 88.9% | 42.4% |
| 3269935 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.74 | 54.0 | 4.23e-01 | 77.8% | 40.9% |
| 3720327 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.74 | 56.0 | 4.44e-01 | 79.6% | 43.0% |
| 3367860 | 376.1.2.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain | 0.72 | 49.0 | 5.33e-01 | 94.4% | 86.7% |
| 3430371 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.72 | 51.0 | 4.23e-01 | 75.9% | 43.2% |
| 5024194 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.71 | 54.0 | 4.82e-01 | 81.5% | 86.7% |
| 3696220 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.71 | 52.0 | 4.01e-01 | 87.0% | 36.8% |
| 3255227 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.70 | 49.0 | 4.05e-01 | 74.1% | 43.2% |
| 3906952 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.70 | 50.0 | 4.01e-01 | 85.2% | 39.4% |
| 3592068 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.70 | 50.0 | 4.93e-01 | 75.9% | 89.7% |
| 4120496 | 377.1.1.8 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › Ribosomal_S26e | 0.69 | 53.0 | 4.78e-01 | 83.3% | 68.0% |
| 3230993 | 376.1.2.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_1 | 0.69 | 47.0 | 4.76e-01 | 94.4% | 70.9% |
| 3907480 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.69 | 49.0 | 4.14e-01 | 100.0% | 45.6% |
| 3914982 | 377.1.1.5 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › LIM | 0.68 | 49.0 | 4.81e-01 | 90.7% | 70.0% |
| 3771418 | 376.1.2.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_1 | 0.67 | 47.0 | 4.88e-01 | 94.4% | 80.0% |
| 3414632 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.67 | 56.0 | 4.67e-01 | 90.7% | 73.3% |
| 3259718 | 376.1.1.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 | 0.67 | 48.0 | 3.88e-01 | 75.9% | 41.0% |
| 3900352 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.67 | 47.0 | 3.92e-01 | 98.1% | 42.1% |
| 3066048 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.67 | 48.0 | 4.09e-01 | 98.1% | 46.2% |
| 3805057 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.67 | 47.0 | 5.08e-01 | 92.6% | 91.1% |
| 3700533 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 53.0 | 3.37e-01 | 100.0% | 17.4% |
| 3903590 | 376.1.2.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_1 | 0.66 | 48.0 | 4.96e-01 | 94.4% | 82.0% |
| 3927543 | 376.1.2.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain | 0.65 | 47.0 | 4.89e-01 | 94.4% | 86.0% |
| 3754819 | 376.1.2.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_1 | 0.64 | 46.0 | 5.06e-01 | 94.4% | 95.3% |
| 3726465 | 376.1.3.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD | 0.62 | 47.0 | 4.44e-01 | 79.6% | 67.7% |
| 3736484 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.61 | 48.0 | 3.98e-01 | 85.2% | 62.1% |
| 5061253 | 376.1.3.97 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › Prok-RING_2 | 0.60 | 50.0 | 4.34e-01 | 90.7% | 62.5% |
| 3655538 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.59 | 48.0 | 4.15e-01 | 100.0% | 57.6% |
| 4945028 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.59 | 50.0 | 4.52e-01 | 100.0% | 68.9% |
| 3938044 | 376.1.2.3 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_4 | 0.57 | 50.0 | 4.22e-01 | 100.0% | 71.0% |
| 3834189 | 376.1.2.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain | 0.56 | 49.0 | 3.71e-01 | 100.0% | 42.3% |
| 4967026 | 376.1.2.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain | 0.54 | 44.0 | 4.17e-01 | 92.6% | 87.7% |
D2
medium
residues 40-112
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sfxB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.57 | 43.0 | 3.92e-01 | 83.6% | 98.1% |
D3
medium
residues 405-482
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.68 | 43.0 | 4.37e-01 | 74.4% | 64.1% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.65 | 53.0 | 5.09e-01 | 94.9% | 75.8% |
| 2a2fX01 | 1.10.357.30 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain | 0.62 | 48.0 | 3.78e-01 | 84.6% | 61.7% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.60 | 44.0 | 3.44e-01 | 92.3% | 35.2% |
| 1f6fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 44.0 | 3.36e-01 | 78.2% | 97.8% |
| 2pusA04 | 6.10.140.300 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 36.0 | 3.26e-01 | 75.6% | 42.6% |
| 3w0lD02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.59 | 50.0 | 3.31e-01 | 94.9% | 92.7% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 39.0 | 3.72e-01 | 70.5% | 62.6% |
| 3iayA07 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.57 | 40.0 | 3.21e-01 | 73.1% | 65.8% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 36.0 | 3.48e-01 | 83.3% | 57.3% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.54 | 38.0 | 4.16e-01 | 75.6% | 100.0% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 35.0 | 3.62e-01 | 83.3% | 69.9% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 45.0 | 3.64e-01 | 94.9% | 99.3% |
| 3cymA03 | 1.10.150.80 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain | 0.52 | 36.0 | 3.51e-01 | 97.4% | 63.6% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.52 | 35.0 | 3.73e-01 | 79.5% | 80.6% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.52 | 44.0 | 3.79e-01 | 96.2% | 91.3% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.52 | 36.0 | 4.06e-01 | 92.3% | 96.7% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 4.06e-01 | 94.9% | 98.4% |
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.51 | 37.0 | 3.58e-01 | 79.5% | 100.0% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.51 | 36.0 | 4.08e-01 | 78.2% | 100.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3482882 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.77 | 54.0 | 6.16e-01 | 87.2% | 95.0% |
| 5058468 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.74 | 49.0 | 5.07e-01 | 73.1% | 72.0% |
| 3479725 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.71 | 52.0 | 3.65e-01 | 76.9% | 26.4% |
| 171404 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.68 | 43.0 | 4.37e-01 | 74.4% | 64.1% |
| 5019542 | 622.4.1.67 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 | 0.65 | 46.0 | 4.29e-01 | 74.4% | 62.6% |
| 3170882 | 603.1.1.210 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Tmemb_170 | 0.62 | 46.0 | 4.04e-01 | 79.5% | 85.0% |
| 4623058 | 5043.1.1.0 ↗ | extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like | 0.62 | 44.0 | 4.71e-01 | 74.4% | 93.8% |
| 3765815 | 515.1.1.1 ↗ | alpha arrays › Transcription factor STAT-4 N-domain › Transcription factor STAT-4 N-domain › Transcription factor STAT-4 N-domain › STAT_int | 0.58 | 41.0 | 3.57e-01 | 83.3% | 47.5% |
| 4986368 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.58 | 41.0 | 3.94e-01 | 74.4% | 77.5% |
| 4438700 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.57 | 42.0 | 4.14e-01 | 92.3% | 72.9% |
| 3598135 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.55 | 40.0 | 3.97e-01 | 100.0% | 71.8% |
| 3176029 | 192.13.1.0 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like | 0.55 | 34.0 | 3.37e-01 | 79.5% | 58.7% |
| 3977114 | 5069.1.1.2 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ni_hydr_CYTB | 0.54 | 39.0 | 2.94e-01 | 79.5% | 35.1% |
| 3451862 | 10.13.1.0 ↗ | beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A | 0.52 | 37.0 | 2.79e-01 | 75.6% | 32.4% |
| 3377936 | 3922.1.1.173 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493 | 0.50 | 37.0 | 3.69e-01 | 82.1% | 100.0% |