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CAKLQF020000002.1__CAH1073184.1__SAMEA5780031_00407__00044

Bact-Vir

CAKLQF020000002.1__CAH1073184.1__SAMEA5780031_00407__00044

Identity

Kingdom:
phage

Quality

94.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 10-50
PDB
Domain cluster: representative
D2 medium residues 54-223
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00115.26 best COX1 155.2 3.60e-45 97.7% 34.6%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6kobA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.98 94.0 6.11e-01 100.0% 27.8%
1m57A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.94 92.0 6.10e-01 100.0% 36.2%
7degA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.85 76.0 5.08e-01 100.0% 27.5%
3mk7A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.83 70.0 4.96e-01 99.4% 32.0%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.77 59.0 6.04e-01 93.5% 81.2%
3wfdB00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.75 69.0 4.89e-01 99.4% 36.1%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.71 53.0 5.54e-01 96.5% 84.5%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 60.0 5.80e-01 94.7% 79.9%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 38.0 3.47e-01 97.6% 40.9%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.70 47.0 4.84e-01 74.7% 71.2%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.69 43.0 4.57e-01 83.5% 69.6%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.68 41.0 4.38e-01 74.7% 68.5%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.67 41.0 4.35e-01 95.3% 68.5%
3gehA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.66 39.0 3.99e-01 71.2% 59.3%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 48.0 4.50e-01 77.1% 96.2%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 49.0 4.15e-01 78.8% 81.8%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 49.0 4.26e-01 78.2% 85.7%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 47.0 4.18e-01 76.5% 85.0%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 47.0 4.03e-01 78.2% 79.7%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 46.0 4.22e-01 75.3% 91.2%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 47.0 4.21e-01 78.2% 87.4%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.61 47.0 4.00e-01 78.2% 86.3%
3i9yA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 42.0 3.78e-01 70.0% 89.1%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.61 42.0 4.45e-01 79.4% 80.3%
3ezuA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 43.0 4.28e-01 95.3% 68.7%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.59 32.0 4.28e-01 71.2% 100.0%
6qumA04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.59 41.0 4.34e-01 94.1% 79.9%
7utzR02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.59 52.0 4.47e-01 98.2% 60.8%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 39.0 4.41e-01 98.2% 88.8%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 43.0 4.64e-01 95.9% 91.8%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 41.0 4.43e-01 96.5% 90.2%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 45.0 4.67e-01 91.8% 91.6%
7powA01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.55 38.0 3.63e-01 94.1% 59.6%
6me6B02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 47.0 4.07e-01 97.6% 57.1%
7dfeA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.54 28.0 3.23e-01 81.2% 64.6%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.54 40.0 3.77e-01 77.6% 90.6%
3ctwB00 1.10.8.930 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Protein of unknown function DUF1465 0.54 36.0 4.20e-01 93.5% 96.7%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 42.0 3.94e-01 96.5% 67.3%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 44.0 4.59e-01 95.3% 94.9%
2j1dG01 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.52 44.0 3.45e-01 91.2% 63.8%
3godB02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.52 40.0 3.76e-01 79.4% 82.2%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.52 43.0 4.39e-01 96.5% 90.1%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 43.0 4.30e-01 90.0% 92.0%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2715167 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.99 97.0 6.17e-01 100.0% 25.8%
4152186 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.97 94.0 6.27e-01 100.0% 31.1%
4929659 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.97 90.0 6.18e-01 100.0% 33.4%
5008926 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 90.0 5.55e-01 100.0% 21.0%
4564446 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.96 90.0 5.54e-01 100.0% 20.8%
4152426 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 93.0 6.25e-01 100.0% 32.9%
4210487 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.94 92.0 6.20e-01 100.0% 33.0%
60213 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.93 91.0 6.17e-01 100.0% 33.9%
4578843 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.93 91.0 6.00e-01 100.0% 31.4%
3102364 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.93 90.0 6.05e-01 100.0% 31.7%
5012069 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.89 85.0 5.85e-01 100.0% 35.0%
5002471 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.79 69.0 4.75e-01 96.5% 30.4%
3729799 632.22.1.5 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › Dynactin 0.75 54.0 4.75e-01 95.3% 52.1%
4992943 632.18.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.75 48.0 5.72e-01 74.1% 94.8%
4229022 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.73 67.0 4.66e-01 96.5% 32.9%
3277855 3562.1.1.3 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › DUF6328 0.71 46.0 4.98e-01 71.2% 76.6%
5038452 5069.1.1.6 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › COX15-CtaA 0.70 44.0 4.77e-01 85.3% 73.1%
4357434 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.68 55.0 5.22e-01 97.6% 72.0%
3483938 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.68 62.0 5.91e-01 98.2% 93.5%
3427456 611.2.1.2 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N 0.67 53.0 5.66e-01 97.6% 94.0%
3964729 5038.1.1.2 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › NnrS 0.67 62.0 4.66e-01 98.2% 50.9%
3167394 874.1.1.0 a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.67 35.0 3.03e-01 98.2% 32.7%
4013425 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.66 56.0 5.81e-01 100.0% 94.4%
4934787 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.66 54.0 5.07e-01 97.1% 70.5%
3534459 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.66 48.0 4.07e-01 74.1% 80.4%
4016645 5086.1.1.176 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF202 0.65 42.0 5.01e-01 76.5% 95.7%
3718391 109.3.1.89 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › CECR6_TMEM121 0.65 53.0 4.73e-01 85.9% 65.5%
5001019 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.65 47.0 4.73e-01 73.5% 91.8%
4931787 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.64 52.0 4.83e-01 100.0% 67.4%
3489372 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.63 47.0 4.25e-01 77.1% 82.6%
3740388 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.63 48.0 4.59e-01 78.2% 84.6%
3690717 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.63 46.0 4.65e-01 74.7% 75.3%
3836944 3615.1.1.54 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › DUF3611 0.62 39.0 4.26e-01 70.6% 75.7%
3522695 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.62 48.0 4.22e-01 81.2% 74.8%
3530722 4177.1.1.150 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF4745 0.61 43.0 4.76e-01 71.8% 96.3%
3608194 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.61 43.0 4.07e-01 72.9% 94.2%
3497934 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.61 46.0 4.04e-01 78.2% 80.4%
3680019 4177.1.1.11 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 0.60 44.0 3.88e-01 75.3% 86.6%
3990526 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.60 45.0 4.09e-01 78.2% 73.0%
4261817 5086.1.1.91 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 0.59 43.0 4.12e-01 74.1% 75.8%
3493924 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.59 43.0 3.70e-01 75.3% 84.4%
3783697 5001.1.1.57 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › DUF3112 0.59 52.0 4.04e-01 95.3% 53.4%
3784582 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.58 44.0 3.83e-01 77.6% 80.8%
3174776 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.57 40.0 3.66e-01 71.2% 91.6%
3620194 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 51.0 4.00e-01 98.8% 53.4%
3244146 5001.1.1.16 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt 0.57 50.0 4.23e-01 97.6% 57.9%
4664960 5073.1.3.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Potassium-transporting ATPase subunit KdpB transmembrane domain 0.56 45.0 3.78e-01 95.9% 49.1%
2507291 3620.1.1.1 alpha bundles › Factor H-binding protein BbCRASP-1 › Factor H-binding protein BbCRASP-1 › Factor H-binding protein BbCRASP-1 › PFam54_60 0.56 45.0 4.40e-01 85.3% 97.8%
3787233 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.55 50.0 4.13e-01 98.2% 72.3%
3709193 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.54 44.0 3.67e-01 84.1% 77.5%
5062612 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.53 38.0 3.73e-01 82.9% 68.3%
3230678 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.52 43.0 4.43e-01 98.2% 90.3%
3460174 192.29.1.104 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 0.52 47.0 4.41e-01 99.4% 96.3%
3894822 192.29.1.104 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 0.52 46.0 4.64e-01 98.2% 94.9%
3964081 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.50 39.0 4.18e-01 90.0% 92.6%
4033669 601.27.1.1 alpha bundles › Four-helical up-and-down bundle › MW0975(SA0943)-like › MW0975(SA0943)-like › YkyA 0.50 45.0 4.36e-01 98.2% 92.7%
D3 medium residues 224-414
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00115.26 best COX1 223.0 9.90e-66 100.0% 42.7%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1m57A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.99 97.0 6.61e-01 100.0% 34.9%
6kobA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.98 96.0 6.39e-01 100.0% 31.8%
1ehkA00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.89 86.0 5.92e-01 100.0% 36.9%
3mk7A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.85 79.0 5.76e-01 100.0% 39.7%
3wfdB00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.80 71.0 5.28e-01 100.0% 39.9%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.73 32.0 4.87e-01 80.1% 97.6%
1qkrB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 48.0 5.01e-01 94.2% 78.3%
4al0A00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.67 50.0 5.59e-01 81.7% 100.0%
2ptqA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.65 49.0 4.29e-01 77.0% 81.7%
5tj5E00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.64 45.0 5.18e-01 79.6% 97.8%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 49.0 4.76e-01 97.9% 72.4%
4gycA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 50.0 4.75e-01 96.9% 72.3%
7cj3A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 55.0 5.01e-01 96.9% 90.3%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 36.0 4.57e-01 79.1% 100.0%
6o7uc01 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.61 45.0 4.60e-01 75.4% 78.4%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 45.0 4.35e-01 74.3% 82.4%
2di3B02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.60 33.0 3.68e-01 85.3% 64.5%
7e4gA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 45.0 4.52e-01 96.9% 75.1%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.59 42.0 4.46e-01 72.3% 94.1%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 40.0 4.39e-01 70.7% 96.8%
4oo2A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 46.0 4.50e-01 85.3% 90.8%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 4.13e-01 81.2% 79.4%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.55 38.0 4.11e-01 73.3% 81.8%
6ko5A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 49.0 4.24e-01 97.9% 77.4%
6gpxB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 49.0 4.39e-01 97.9% 77.2%
3zevB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 49.0 4.18e-01 97.9% 75.3%
4alyB00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.52 39.0 3.95e-01 76.4% 100.0%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.51 33.0 3.99e-01 93.2% 96.2%
2g38B00 1.20.1260.20 Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily 0.50 39.0 4.07e-01 95.3% 87.9%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.50 33.0 3.96e-01 79.6% 96.2%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2715167 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 1.00 98.0 6.38e-01 100.0% 28.9%
4428270 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.99 98.0 6.62e-01 100.0% 36.2%
4646286 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.99 98.0 6.62e-01 100.0% 34.4%
4152426 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.99 98.0 6.76e-01 100.0% 37.6%
4929659 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.99 97.0 6.82e-01 100.0% 39.4%
60213 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.98 97.0 6.75e-01 100.0% 38.1%
4578843 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 97.0 6.55e-01 100.0% 34.1%
4152186 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 96.0 6.57e-01 100.0% 35.2%
4210487 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 97.0 6.68e-01 100.0% 37.1%
60209 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.98 96.0 6.60e-01 100.0% 35.6%
5008926 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 96.0 6.06e-01 100.0% 24.7%
4564446 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.98 96.0 6.05e-01 100.0% 24.5%
3102364 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 96.0 6.57e-01 100.0% 35.8%
4333395 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.97 95.0 6.71e-01 100.0% 40.0%
4631115 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.94 89.0 6.40e-01 100.0% 40.4%
5012069 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.93 89.0 6.25e-01 100.0% 37.2%
60212 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.89 86.0 5.92e-01 100.0% 36.9%
4229022 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.85 80.0 5.68e-01 100.0% 37.8%
3407685 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.72 46.0 5.37e-01 81.2% 89.6%
3276757 601.1.2.3 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C 0.67 55.0 5.91e-01 92.7% 100.0%
None 0.65 55.0 5.60e-01 98.4% 90.5%
3394093 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.65 50.0 5.41e-01 81.2% 95.0%
3940018 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.64 46.0 4.26e-01 73.8% 100.0%
3481369 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 55.0 5.01e-01 96.9% 69.2%
3208482 632.22.1.5 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › Dynactin 0.62 47.0 3.21e-01 79.6% 37.6%
3751245 633.23.1.8 alpha bundles › Bromodomain-like › Claudin › Claudin › DUF4534 0.61 42.0 4.71e-01 71.2% 89.3%
3786466 601.1.2.75 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.59 51.0 4.89e-01 97.9% 80.5%
5011553 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.59 46.0 4.75e-01 80.1% 96.7%
3726235 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.58 46.0 4.39e-01 83.2% 99.1%
3727292 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.57 43.0 4.63e-01 81.2% 90.6%
3262781 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 41.0 4.50e-01 75.4% 94.8%
3172149 5001.1.1.8 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII 0.55 47.0 4.34e-01 96.9% 71.4%
3280501 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.55 48.0 4.70e-01 100.0% 87.1%
5076444 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.55 47.0 4.61e-01 97.9% 85.7%
3416635 5054.1.1.61 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.55 48.0 4.52e-01 96.9% 77.0%
3923069 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 48.0 3.97e-01 99.0% 62.5%
3715565 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.54 47.0 4.56e-01 97.9% 84.1%
3743351 611.9.1.6 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Ran-binding 0.53 37.0 4.10e-01 72.3% 91.0%
3572867 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 47.0 3.80e-01 96.9% 74.7%
3711435 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.53 46.0 4.36e-01 97.4% 88.3%
3196950 611.7.1.12 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Goodbye 0.52 40.0 3.95e-01 80.1% 97.1%
3732232 109.3.1.293 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ran-binding 0.52 39.0 4.34e-01 81.7% 97.4%
D4 medium residues 415-527
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00115.26 best COX1 95.9 3.70e-27 81.4% 22.0%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1m57A00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.95 91.0 5.59e-01 100.0% 20.5%
6kobA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.95 88.0 5.31e-01 95.6% 18.0%
1ehkA00 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.88 82.0 5.09e-01 98.2% 21.7%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.73 59.0 5.19e-01 98.2% 58.9%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 47.0 4.22e-01 90.3% 48.1%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 49.0 3.92e-01 70.8% 37.1%
3terA00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 49.0 4.80e-01 70.8% 73.9%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.70 48.0 5.05e-01 70.8% 78.2%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.69 61.0 5.17e-01 99.1% 94.8%
2ap3A00 1.20.120.570 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like 0.68 62.0 5.21e-01 100.0% 65.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 55.0 5.47e-01 95.6% 83.1%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 60.0 4.58e-01 100.0% 79.7%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.67 51.0 5.22e-01 87.6% 83.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 49.0 5.01e-01 78.8% 94.6%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.65 57.0 4.92e-01 95.6% 95.4%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 58.0 4.49e-01 100.0% 85.3%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 58.0 4.45e-01 99.1% 72.7%
6gpxB00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.64 54.0 4.03e-01 98.2% 38.4%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.64 46.0 4.62e-01 85.0% 73.5%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.64 57.0 4.37e-01 100.0% 87.4%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.63 55.0 4.94e-01 100.0% 69.3%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.62 48.0 4.07e-01 82.3% 76.5%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 53.0 4.15e-01 98.2% 75.2%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.60 53.0 3.85e-01 99.1% 45.5%
1ux5A03 1.20.58.2220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Formin, FH2 domain 0.59 41.0 3.21e-01 70.8% 60.3%
5lweA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 48.0 3.64e-01 98.2% 36.7%
3wurA00 1.20.1420.60 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › 0.58 44.0 3.92e-01 97.3% 56.2%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 34.0 3.47e-01 83.2% 59.1%
3vkgB06 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.57 49.0 3.79e-01 93.8% 70.6%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.53 44.0 4.45e-01 93.8% 89.3%
5azsC01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.52 48.0 3.34e-01 100.0% 57.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 42.0 4.37e-01 99.1% 95.3%
2qnlA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 44.0 3.96e-01 98.2% 97.5%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2715167 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.98 96.0 5.67e-01 100.0% 17.1%
4152426 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.97 93.0 5.75e-01 100.0% 22.0%
60213 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.96 93.0 5.80e-01 100.0% 22.6%
4578843 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 93.0 5.67e-01 100.0% 20.9%
4152186 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 91.0 5.59e-01 100.0% 20.6%
3102364 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 92.0 5.63e-01 100.0% 20.9%
3202015 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.96 92.0 5.74e-01 100.0% 23.3%
4646286 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.95 92.0 5.59e-01 100.0% 20.2%
4929659 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.95 91.0 5.73e-01 100.0% 23.7%
60209 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.94 90.0 5.54e-01 100.0% 20.9%
5008926 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.94 90.0 5.22e-01 100.0% 14.4%
4564446 5038.1.1.0 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like 0.94 90.0 5.22e-01 100.0% 14.3%
4428270 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.94 90.0 5.51e-01 100.0% 21.3%
4210487 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.91 85.0 5.27e-01 97.3% 21.6%
2773737 3892.1.1.2 alpha bundles › Transhydrogeanse domain II › Transhydrogeanse domain II › Transhydrogeanse domain II › PNTB_4TM 0.77 47.0 3.90e-01 77.0% 36.5%
3181110 5086.1.1.110 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HisKA 0.75 52.0 5.68e-01 70.8% 89.5%
4234530 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.75 52.0 5.24e-01 71.7% 93.0%
3972622 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 49.0 5.24e-01 70.8% 95.0%
3472905 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.71 65.0 5.39e-01 100.0% 89.7%
3875862 192.7.1.83 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › KIF9 0.70 51.0 4.94e-01 75.2% 100.0%
3697275 192.29.1.104 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 0.70 63.0 5.36e-01 98.2% 78.8%
3479389 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 64.0 5.40e-01 100.0% 94.1%
4468389 5086.1.1.101 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.69 48.0 4.72e-01 70.8% 71.7%
3911413 148.1.3.13 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.69 51.0 3.66e-01 77.0% 48.4%
4988447 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.68 62.0 6.20e-01 99.1% 96.5%
3651298 5059.1.1.4 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Nuc_sug_transp 0.68 57.0 3.96e-01 90.3% 64.3%
4581983 5086.1.1.13 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB 0.68 55.0 5.09e-01 85.0% 93.6%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.68 55.0 5.29e-01 85.8% 100.0%
5018556 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.68 62.0 6.17e-01 100.0% 97.4%
4324117 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 46.0 3.25e-01 70.8% 94.0%
3287601 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.67 46.0 5.01e-01 70.8% 87.2%
4408647 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 51.0 5.29e-01 79.6% 96.2%
3424354 226.1.1.20 a+b two layers › POZ domain › POZ domain › POZ domain › PF30468, PF30469 0.66 46.0 3.81e-01 70.8% 48.4%
4423640 5059.1.1.5 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.66 59.0 4.20e-01 100.0% 56.1%
3892397 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.65 56.0 4.08e-01 92.0% 74.9%
4019924 601.39.1.5 alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 › DUF7784 0.65 59.0 4.86e-01 100.0% 55.1%
3704193 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.65 57.0 4.40e-01 95.6% 75.1%
3515022 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.64 47.0 3.93e-01 85.0% 47.2%
3908810 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.64 57.0 4.26e-01 100.0% 79.7%
3739377 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.64 57.0 4.23e-01 99.1% 83.1%
4876530 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 45.0 5.19e-01 82.3% 100.0%
3178900 192.2.1.30 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Uds1 0.63 49.0 4.47e-01 80.5% 92.4%
3463843 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.62 48.0 4.61e-01 97.3% 70.5%
3178891 632.25.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor N-terminal domain › GBS CAMP factor N-terminal domain › NACHT_N 0.62 52.0 4.13e-01 92.0% 69.4%
4884076 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.61 53.0 5.24e-01 100.0% 89.2%
4878961 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.60 51.0 5.28e-01 100.0% 97.2%
3176852 632.2.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains 0.60 54.0 5.22e-01 100.0% 100.0%
3746563 3755.3.1.123 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin 0.60 50.0 4.62e-01 92.9% 86.7%
3935633 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.60 49.0 4.23e-01 90.3% 60.0%
3216129 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.59 48.0 4.66e-01 92.9% 79.2%
3719227 109.4.1.623 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.58 40.0 2.72e-01 70.8% 25.6%
3685798 632.25.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › GBS CAMP factor N-terminal domain › GBS CAMP factor N-terminal domain 0.57 49.0 4.34e-01 96.5% 72.9%
3730963 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.57 52.0 3.41e-01 98.2% 78.9%
3348093 604.1.1.149 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › CASP_dom 0.53 47.0 4.79e-01 96.5% 100.0%
3636764 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 45.0 2.76e-01 94.7% 24.6%
D5 medium residues 541-661
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1iq0A03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.60 33.0 3.37e-01 73.6% 55.2%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 30.0 3.10e-01 76.0% 51.3%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 38.0 3.81e-01 71.1% 83.1%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2715167 5038.1.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › Cytochrome c oxidase subunit I-like › COX1 0.97 94.0 5.65e-01 100.0% 18.3%
3718513 109.4.1.195 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_11 0.79 35.0 2.59e-01 72.7% 18.2%
140767 632.8.1.3 alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › DUF6853 0.55 38.0 3.81e-01 71.1% 83.1%
3695977 3922.1.1.133 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PRM1 0.54 38.0 4.07e-01 76.0% 84.8%