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CAKLQF020000002.1__CAH1073714.1__SAMEA5780031_00636__00265
Bact-VirCAKLQF020000002.1__CAH1073714.1__SAMEA5780031_00636__00265
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 22-184
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03591.20 best | AzlC | 120.7 | 9.20e-35 | 84.0% | 100.0% |
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.63 | 45.0 | 4.40e-01 | 97.5% | 67.2% |
| 6pnjL00 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.58 | 39.0 | 4.05e-01 | 89.6% | 71.2% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 30.0 | 3.33e-01 | 85.3% | 60.3% |
| 7dwqL01 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.57 | 38.0 | 4.31e-01 | 87.7% | 87.2% |
| 4ecgA00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.56 | 39.0 | 2.98e-01 | 70.6% | 51.4% |
| 3p7nA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 22.0 | 3.31e-01 | 87.7% | 83.3% |
| 1jwnA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 32.0 | 3.41e-01 | 85.3% | 62.8% |
| 5f64A02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 22.0 | 3.17e-01 | 87.7% | 80.0% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 40.0 | 3.41e-01 | 77.9% | 88.9% |
| 2di3B02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 39.0 | 3.98e-01 | 90.8% | 78.7% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 40.0 | 3.62e-01 | 78.5% | 100.0% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 29.0 | 2.93e-01 | 86.5% | 48.0% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 28.0 | 3.51e-01 | 88.3% | 81.6% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 29.0 | 3.48e-01 | 90.8% | 80.4% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 32.0 | 3.57e-01 | 90.2% | 75.4% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.52 | 35.0 | 4.13e-01 | 82.8% | 99.1% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 44.0 | 3.97e-01 | 91.4% | 100.0% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 34.0 | 3.16e-01 | 100.0% | 50.9% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 43.0 | 3.77e-01 | 91.4% | 96.0% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 35.0 | 3.67e-01 | 90.8% | 78.5% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3165973 | 3538.1.1.10 ↗ | extended segments › MerF › MerF › MerF › AzlC | 0.85 | 81.0 | 7.87e-01 | 100.0% | 96.6% |
| 3636505 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.64 | 47.0 | 3.92e-01 | 100.0% | 45.1% |
| 3199349 | 1188.1.1.0 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter | 0.61 | 47.0 | 3.87e-01 | 100.0% | 46.4% |
| 3735237 | 601.19.1.18 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C | 0.55 | 34.0 | 3.59e-01 | 87.7% | 66.0% |
| 4023025 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.54 | 31.0 | 3.22e-01 | 85.3% | 60.0% |
| 5038416 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.52 | 43.0 | 4.24e-01 | 89.0% | 82.4% |
| 4939326 | 1079.1.1.19 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DUF2162 | 0.52 | 47.0 | 4.55e-01 | 98.2% | 98.4% |
| 4011226 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 48.0 | 4.46e-01 | 100.0% | 89.5% |
| 3953897 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 48.0 | 4.34e-01 | 100.0% | 88.4% |
| 3949320 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 48.0 | 4.47e-01 | 100.0% | 89.5% |
| 5058267 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.51 | 37.0 | 2.81e-01 | 73.6% | 44.6% |
| 4038359 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 43.0 | 3.48e-01 | 89.6% | 89.4% |
| 4989767 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.51 | 47.0 | 4.42e-01 | 100.0% | 95.9% |
D2
high
residues 188-237
Domain cluster:
representative
CATH (53)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ukfA00 | 3.90.70.20 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.80 | 63.0 | 4.19e-01 | 86.0% | 39.9% |
| 4ezcB00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.78 | 70.0 | 4.18e-01 | 100.0% | 30.3% |
| 7dfeA01 | 1.10.274.60 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain | 0.77 | 61.0 | 4.56e-01 | 90.0% | 34.6% |
| 1b8bA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.77 | 65.0 | 3.70e-01 | 98.0% | 9.0% |
| 1iuqA01 | 1.10.1200.50 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal | 0.76 | 65.0 | 5.74e-01 | 100.0% | 78.9% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.76 | 52.0 | 3.35e-01 | 72.0% | 18.2% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.75 | 57.0 | 5.26e-01 | 82.0% | 67.2% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.75 | 62.0 | 5.45e-01 | 94.0% | 81.3% |
| 1sg7A00 | 1.10.1740.70 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB | 0.75 | 66.0 | 5.78e-01 | 100.0% | 81.3% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 52.0 | 4.56e-01 | 76.0% | 52.1% |
| 2oo2A00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.74 | 54.0 | 4.61e-01 | 76.0% | 52.6% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.73 | 60.0 | 4.41e-01 | 90.0% | 78.9% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.73 | 52.0 | 4.71e-01 | 76.0% | 77.6% |
| 2qgsB01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.73 | 58.0 | 4.77e-01 | 86.0% | 58.0% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.72 | 62.0 | 4.97e-01 | 100.0% | 61.2% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.72 | 59.0 | 5.41e-01 | 94.0% | 91.2% |
| 6he1B01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.72 | 50.0 | 4.64e-01 | 76.0% | 57.8% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 57.0 | 5.59e-01 | 94.0% | 87.7% |
| 1a8rA01 | 1.10.286.10 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain | 0.71 | 60.0 | 5.07e-01 | 96.0% | 62.4% |
| 5b1aC01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 51.0 | 4.58e-01 | 76.0% | 76.5% |
| 3u9rB02 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.71 | 60.0 | 3.82e-01 | 100.0% | 74.5% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.70 | 52.0 | 4.58e-01 | 82.0% | 61.8% |
| 2xzmV01 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.69 | 50.0 | 4.69e-01 | 90.0% | 63.9% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.68 | 56.0 | 3.86e-01 | 92.0% | 31.8% |
| 2f93B00 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 55.0 | 5.49e-01 | 94.0% | 92.2% |
| 1v4gA01 | 6.10.140.800 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 47.0 | 4.33e-01 | 86.0% | 55.1% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 52.0 | 3.53e-01 | 84.0% | 58.2% |
| 2yxhA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.67 | 52.0 | 3.96e-01 | 84.0% | 38.1% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.67 | 52.0 | 3.85e-01 | 84.0% | 34.7% |
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 47.0 | 4.73e-01 | 78.0% | 73.1% |
| 1is8A01 | 1.10.286.10 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain | 0.66 | 53.0 | 5.12e-01 | 96.0% | 86.7% |
| 4uqfG01 | 1.10.286.10 | Mainly Alpha › Orthogonal Bundle › GTP Cyclohydrolase I; Chain A, domain 1 › GTP cyclohydrolase I, N-terminal domain | 0.66 | 53.0 | 5.31e-01 | 94.0% | 94.2% |
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.65 | 53.0 | 4.20e-01 | 100.0% | 98.3% |
| 1e3pA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.65 | 53.0 | 4.58e-01 | 94.0% | 63.9% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.64 | 51.0 | 4.17e-01 | 84.0% | 46.7% |
| 1o9gA02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 47.0 | 5.04e-01 | 80.0% | 97.7% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.64 | 48.0 | 3.57e-01 | 82.0% | 39.5% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 49.0 | 4.19e-01 | 92.0% | 50.6% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.62 | 53.0 | 3.95e-01 | 98.0% | 78.2% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.62 | 51.0 | 4.80e-01 | 92.0% | 73.8% |
| 1bbhA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.61 | 52.0 | 3.83e-01 | 94.0% | 42.0% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.61 | 50.0 | 3.70e-01 | 96.0% | 80.8% |
| 2wapA00 | 3.90.1300.10 | Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain | 0.61 | 52.0 | 3.00e-01 | 100.0% | 38.6% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.60 | 51.0 | 3.94e-01 | 98.0% | 45.5% |
| 1cgnA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.60 | 54.0 | 4.07e-01 | 100.0% | 90.3% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 51.0 | 4.42e-01 | 92.0% | 62.7% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 4.47e-01 | 90.0% | 84.1% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 3.84e-01 | 92.0% | 41.6% |
| 3nufB00 | 1.10.1790.10 | Mainly Alpha › Orthogonal Bundle › PTS-regulatory domain, PRD › PRD domain | 0.60 | 48.0 | 3.85e-01 | 94.0% | 45.5% |
| 2ffjA02 | 1.10.285.20 | Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 | 0.60 | 43.0 | 4.12e-01 | 84.0% | 63.1% |
| 6cgvM01 | 1.20.120.1500 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pre-hexon-linking protein IIIa | 0.60 | 47.0 | 3.62e-01 | 94.0% | 94.0% |
| 3iv7A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.59 | 53.0 | 3.52e-01 | 100.0% | 34.2% |
| 1zhcA00 | 6.10.280.50 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 49.0 | 4.37e-01 | 100.0% | 86.8% |
ECOD (52)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4221177 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.89 | 69.0 | 6.93e-01 | 82.0% | 90.0% |
| 5077996 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.89 | 82.0 | 4.92e-01 | 100.0% | 63.7% |
| 3416059 | 148.1.1.25 ↗ | alpha arrays › Histone-like › Histone-related › Histone › Tim17 | 0.87 | 73.0 | 5.10e-01 | 94.0% | 45.2% |
| 3741742 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.85 | 77.0 | 4.75e-01 | 100.0% | 40.0% |
| 3946553 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.85 | 73.0 | 4.17e-01 | 92.0% | 14.6% |
| 4241417 | 219.1.1.21 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C58 | 0.83 | 71.0 | 4.48e-01 | 94.0% | 36.6% |
| 4569740 | 3860.1.1.1 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › IQ | 0.83 | 72.0 | 5.51e-01 | 96.0% | 43.6% |
| 4196671 | 1075.5.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ | 0.80 | 72.0 | 4.66e-01 | 100.0% | 87.9% |
| 2905612 | 592.4.1.1 ↗ | alpha arrays › PWI domain-like › Repetitive domains of egg case silk protein TuSp1 › Repetitive domains of egg case silk protein TuSp1 › RP1-2 | 0.80 | 64.0 | 4.84e-01 | 90.0% | 37.6% |
| 4004120 | 1075.5.1.5 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 | 0.80 | 68.0 | 3.97e-01 | 96.0% | 12.1% |
| 7384 | 219.1.1.21 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C58 | 0.80 | 63.0 | 4.19e-01 | 86.0% | 39.9% |
| 3506517 | 7023.1.1.4 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › Tim17 | 0.79 | 65.0 | 4.84e-01 | 94.0% | 36.8% |
| 1120983 | 103.9.1.1 ↗ | alpha arrays › RuvA-C › RanGAP2 N-terminal domain › RanGAP2 N-terminal domain › WPP | 0.79 | 57.0 | 5.57e-01 | 80.0% | 69.6% |
| 3609311 | 7575.1.1.0 ↗ | a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like | 0.78 | 65.0 | 4.36e-01 | 92.0% | 45.4% |
| 4483958 | 6155.2.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › PnuC › PnuC › NMN_transporter | 0.78 | 66.0 | 4.23e-01 | 96.0% | 20.6% |
| 3970388 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.77 | 63.0 | 3.67e-01 | 92.0% | 14.0% |
| 3209229 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.76 | 63.0 | 4.00e-01 | 96.0% | 18.5% |
| 3518379 | 3502.1.1.1 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG | 0.75 | 53.0 | 5.20e-01 | 76.0% | 76.4% |
| 5013775 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.75 | 58.0 | 3.39e-01 | 88.0% | 13.9% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.73 | 53.0 | 3.96e-01 | 76.0% | 75.0% |
| 3906819 | 192.17.1.6 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › CC2D1A-B_DM14 | 0.73 | 52.0 | 3.68e-01 | 76.0% | 39.3% |
| 4999592 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.72 | 56.0 | 4.94e-01 | 86.0% | 81.3% |
| 4128045 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.72 | 62.0 | 5.07e-01 | 100.0% | 66.3% |
| 3415494 | 5029.1.1.0 ↗ | extended segments › Oligosaccharyltransferase subunit ost4p › Oligosaccharyltransferase subunit ost4p › Oligosaccharyltransferase subunit ost4p | 0.71 | 55.0 | 5.19e-01 | 84.0% | 85.0% |
| 5040031 | 632.22.1.199 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PLDc_N | 0.70 | 60.0 | 5.10e-01 | 100.0% | 84.7% |
| 3220837 | 397.7.1.0 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 | 0.69 | 47.0 | 4.99e-01 | 72.0% | 100.0% |
| 3706387 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.68 | 52.0 | 4.04e-01 | 82.0% | 39.0% |
| 3599328 | 616.1.1.6 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Mpo1-like | 0.68 | 59.0 | 4.89e-01 | 98.0% | 61.1% |
| 3067828 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.68 | 58.0 | 5.10e-01 | 100.0% | 79.5% |
| 3955928 | 7525.1.1.1 ↗ | a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_1 | 0.68 | 54.0 | 3.41e-01 | 92.0% | 16.5% |
| 3290838 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 58.0 | 4.53e-01 | 100.0% | 58.3% |
| 4642209 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.67 | 56.0 | 4.01e-01 | 94.0% | 32.0% |
| 5027220 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.67 | 55.0 | 5.22e-01 | 94.0% | 85.0% |
| 4953793 | 5076.2.1.3 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF4013 | 0.67 | 57.0 | 3.85e-01 | 98.0% | 48.8% |
| 4084096 | 316.1.1.60 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2, DUF294 | 0.67 | 55.0 | 3.99e-01 | 94.0% | 32.0% |
| 4021030 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 56.0 | 3.89e-01 | 96.0% | 27.6% |
| 3965150 | 316.1.1.43 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF294 | 0.67 | 55.0 | 3.97e-01 | 94.0% | 32.0% |
| 5023828 | 159.1.1.1 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG | 0.65 | 46.0 | 3.79e-01 | 74.0% | 43.2% |
| 3726873 | 601.1.2.108 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PigN | 0.65 | 55.0 | 3.84e-01 | 100.0% | 63.3% |
| 3631283 | 5069.1.1.82 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PigN | 0.65 | 56.0 | 3.81e-01 | 100.0% | 60.5% |
| 4927596 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 53.0 | 3.86e-01 | 90.0% | 55.4% |
| 5006188 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.63 | 52.0 | 4.95e-01 | 92.0% | 93.3% |
| 4100663 | 7575.1.1.11 ↗ | a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › PF31181 | 0.62 | 47.0 | 3.00e-01 | 94.0% | 14.5% |
| 3709588 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.62 | 55.0 | 4.68e-01 | 100.0% | 76.2% |
| 3961486 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.61 | 50.0 | 3.52e-01 | 96.0% | 33.1% |
| 4181278 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.60 | 52.0 | 4.54e-01 | 96.0% | 77.3% |
| 4927307 | 632.11.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DUF357 | 0.60 | 53.0 | 4.50e-01 | 100.0% | 83.5% |
| 3966756 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.60 | 48.0 | 2.85e-01 | 94.0% | 38.1% |
| 3611066 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.59 | 52.0 | 4.67e-01 | 100.0% | 87.1% |
| 3176029 | 192.13.1.0 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like | 0.59 | 41.0 | 3.51e-01 | 76.0% | 45.0% |
| 3282145 | 618.2.1.1 ↗ | a+b complex topology › DNA mimic protein DMP12-like › Immunity protein CdiI › Immunity protein CdiI › DUF6247 | 0.57 | 50.0 | 4.85e-01 | 100.0% | 100.0% |
| 1388524 | 243.17.1.1 ↗ | a+b two layers › Cystatin-like › C-terminal domain of PatG › C-terminal domain of PatG › PatG_C | 0.56 | 46.0 | 3.50e-01 | 98.0% | 50.8% |