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CAKLQF020000003.1__CAH1076123.1__SAMEA5780031_00677__00013
Bact-VirCAKLQF020000003.1__CAH1076123.1__SAMEA5780031_00677__00013
Identity
- Kingdom:
- phage
Quality
92.8
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 1-97
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04279.21 best | IspA | 59.1 | 9.30e-16 | 100.0% | 42.3% |
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.73 | 52.0 | 5.83e-01 | 95.9% | 94.7% |
| 2fu2A00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.73 | 43.0 | 4.69e-01 | 88.7% | 71.8% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 45.0 | 4.47e-01 | 100.0% | 63.0% |
| 8sorA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.66 | 48.0 | 3.28e-01 | 95.9% | 21.3% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.63 | 57.0 | 4.57e-01 | 100.0% | 61.8% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.63 | 57.0 | 4.53e-01 | 100.0% | 61.2% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 55.0 | 4.89e-01 | 95.9% | 94.2% |
| 1b3uA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.63 | 38.0 | 2.33e-01 | 92.8% | 9.9% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.62 | 49.0 | 4.84e-01 | 100.0% | 81.4% |
| 2wyhB04 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.62 | 43.0 | 4.33e-01 | 75.3% | 70.3% |
| 4oo2A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 44.0 | 3.48e-01 | 76.3% | 48.5% |
| 6t0bf00 | 1.25.40.40 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Cytochrome c oxidase, subunit Va/VI | 0.61 | 37.0 | 3.65e-01 | 93.8% | 55.9% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.61 | 48.0 | 4.49e-01 | 100.0% | 68.0% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 44.0 | 4.23e-01 | 96.9% | 66.4% |
| 3qc1A01 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.60 | 46.0 | 3.99e-01 | 94.8% | 53.0% |
| 2a2cA03 | 1.20.1440.340 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.60 | 48.0 | 4.26e-01 | 86.6% | 71.7% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.60 | 54.0 | 4.32e-01 | 100.0% | 75.0% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 53.0 | 4.15e-01 | 100.0% | 56.9% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.59 | 51.0 | 4.01e-01 | 93.8% | 89.7% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 51.0 | 4.57e-01 | 95.9% | 79.0% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.59 | 51.0 | 4.63e-01 | 97.9% | 72.9% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 48.0 | 3.68e-01 | 88.7% | 41.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 51.0 | 5.08e-01 | 95.9% | 91.3% |
| 2imsA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.58 | 44.0 | 3.68e-01 | 100.0% | 47.2% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 43.0 | 4.68e-01 | 76.3% | 96.2% |
| 6orcB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 34.0 | 3.09e-01 | 92.8% | 41.8% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.56 | 49.0 | 4.77e-01 | 97.9% | 89.9% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.56 | 49.0 | 4.71e-01 | 97.9% | 91.7% |
| 2n1rA00 | 1.10.150.90 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 | 0.55 | 38.0 | 3.47e-01 | 93.8% | 53.0% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.53 | 46.0 | 3.70e-01 | 95.9% | 55.4% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.53 | 32.0 | 3.52e-01 | 93.8% | 73.1% |
| 3u37A02 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.51 | 41.0 | 3.10e-01 | 88.7% | 75.4% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4102879 | 604.12.1.76 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › IspA | 0.94 | 73.0 | 8.04e-01 | 95.9% | 96.2% |
| 3341433 | 604.12.1.77 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PMEI | 0.72 | 56.0 | 5.74e-01 | 95.9% | 85.3% |
| 3737294 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.69 | 50.0 | 4.64e-01 | 95.9% | 60.8% |
| 4999868 | 604.1.1.264 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Oxidored_q2 | 0.66 | 52.0 | 5.34e-01 | 96.9% | 91.1% |
| 5032645 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.66 | 44.0 | 3.07e-01 | 71.1% | 23.6% |
| 3804328 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.65 | 56.0 | 4.34e-01 | 95.9% | 46.8% |
| 3492369 | 622.4.1.21 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Frag1 | 0.64 | 55.0 | 5.14e-01 | 92.8% | 98.3% |
| 3241365 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.63 | 45.0 | 3.74e-01 | 73.2% | 53.1% |
| 3226778 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.63 | 55.0 | 4.40e-01 | 95.9% | 85.3% |
| 3927442 | 601.1.1.95 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › F_actin_bind | 0.62 | 56.0 | 5.05e-01 | 100.0% | 82.2% |
| 3817246 | 192.29.1.27 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF1218 | 0.62 | 57.0 | 4.60e-01 | 100.0% | 78.9% |
| 5077923 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.62 | 55.0 | 4.49e-01 | 100.0% | 85.9% |
| 3392967 | 604.1.1.253 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TRAM_LAG1_CLN8 | 0.61 | 52.0 | 3.71e-01 | 93.8% | 35.5% |
| 3543076 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.60 | 53.0 | 4.17e-01 | 95.9% | 82.0% |
| 3457612 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.60 | 54.0 | 4.49e-01 | 100.0% | 79.4% |
| 3767618 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.60 | 52.0 | 4.77e-01 | 94.8% | 73.6% |
| 3561892 | 4106.1.1.0 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack | 0.60 | 52.0 | 4.55e-01 | 95.9% | 67.6% |
| 3214191 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 51.0 | 4.90e-01 | 95.9% | 90.4% |
| 4268045 | 5069.1.1.61 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF28674 | 0.59 | 53.0 | 4.72e-01 | 100.0% | 84.3% |
| 3606649 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 50.0 | 3.75e-01 | 94.8% | 60.4% |
| 4648744 | 4070.1.1.3 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › DUF3267 | 0.59 | 52.0 | 4.35e-01 | 97.9% | 68.5% |
| 3587850 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.59 | 53.0 | 4.68e-01 | 100.0% | 82.1% |
| 3647744 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.58 | 51.0 | 4.74e-01 | 100.0% | 96.8% |
| 4078998 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.58 | 47.0 | 4.65e-01 | 96.9% | 81.0% |
| 4499656 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.58 | 47.0 | 4.17e-01 | 97.9% | 61.4% |
| 4040950 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.57 | 45.0 | 4.34e-01 | 96.9% | 74.3% |
| 4390324 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.57 | 46.0 | 4.55e-01 | 95.9% | 79.8% |
| 3597047 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.57 | 49.0 | 3.60e-01 | 95.9% | 42.3% |
| 4959126 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.57 | 50.0 | 4.29e-01 | 100.0% | 77.5% |
| 4960309 | 5058.1.1.101 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › DUF1622 | 0.57 | 48.0 | 4.67e-01 | 95.9% | 85.5% |
| 5038204 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.56 | 48.0 | 3.46e-01 | 93.8% | 63.9% |
| 4014082 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.55 | 43.0 | 4.20e-01 | 93.8% | 75.5% |
| 4999825 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.55 | 42.0 | 4.22e-01 | 86.6% | 79.0% |
| 3995294 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.55 | 49.0 | 4.50e-01 | 97.9% | 76.0% |
| 3932719 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 42.0 | 3.26e-01 | 83.5% | 68.9% |
| 3971686 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.53 | 48.0 | 4.18e-01 | 97.9% | 94.3% |
| 3520392 | 109.4.1.1399 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tuberin, DUF3384 | 0.52 | 44.0 | 2.57e-01 | 95.9% | 10.2% |
| 3328315 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.51 | 47.0 | 3.96e-01 | 97.9% | 94.8% |
| 3291425 | 191.1.1.44 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_43 | 0.51 | 46.0 | 4.31e-01 | 99.0% | 100.0% |
| 5001551 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.51 | 45.0 | 3.77e-01 | 96.9% | 75.2% |
| 4620055 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.50 | 43.0 | 3.31e-01 | 97.9% | 62.5% |
D2
high
residues 98-195
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04279.21 best | IspA | 59.5 | 6.90e-16 | 100.0% | 53.1% |
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4od4A02 | 1.20.120.1780 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase | 0.72 | 50.0 | 4.72e-01 | 100.0% | 59.7% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.70 | 60.0 | 5.63e-01 | 100.0% | 76.0% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 48.0 | 4.07e-01 | 98.0% | 45.5% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.68 | 53.0 | 4.06e-01 | 81.6% | 71.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.67 | 35.0 | 3.70e-01 | 73.5% | 55.3% |
| 2yinA01 | 1.25.40.410 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DOCK DHR2 domain, lobe A | 0.65 | 34.0 | 3.09e-01 | 75.5% | 36.7% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 46.0 | 4.55e-01 | 74.5% | 70.6% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.64 | 52.0 | 4.55e-01 | 88.8% | 88.9% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.64 | 45.0 | 4.43e-01 | 72.4% | 100.0% |
| 1aluA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 46.0 | 3.89e-01 | 74.5% | 97.5% |
| 3vz3A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.63 | 57.0 | 4.11e-01 | 98.0% | 71.5% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.62 | 45.0 | 4.83e-01 | 74.5% | 90.2% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 41.0 | 3.55e-01 | 76.5% | 43.3% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 50.0 | 4.58e-01 | 92.9% | 65.4% |
| 1wu3I00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 43.0 | 3.64e-01 | 72.4% | 70.2% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.62 | 49.0 | 4.00e-01 | 100.0% | 46.2% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 42.0 | 3.54e-01 | 70.4% | 65.1% |
| 1hwyA03 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.60 | 53.0 | 3.85e-01 | 100.0% | 88.8% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.59 | 40.0 | 4.48e-01 | 70.4% | 100.0% |
| 4lqqB00 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.59 | 40.0 | 3.52e-01 | 91.8% | 46.6% |
| 7tzoA01 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.58 | 40.0 | 3.38e-01 | 96.9% | 40.2% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.58 | 41.0 | 3.48e-01 | 74.5% | 48.4% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.57 | 49.0 | 3.77e-01 | 93.9% | 78.8% |
| 6vddD01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.57 | 44.0 | 3.55e-01 | 81.6% | 84.6% |
| 3bg2A03 | 1.10.3410.10 | Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain | 0.57 | 45.0 | 4.62e-01 | 92.9% | 90.6% |
| 4kk2B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 48.0 | 3.32e-01 | 94.9% | 48.5% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.56 | 50.0 | 4.65e-01 | 100.0% | 89.6% |
| 1werA01 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.55 | 38.0 | 3.20e-01 | 71.4% | 57.4% |
| 1bm9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 38.0 | 3.59e-01 | 71.4% | 91.7% |
| 1otvA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.55 | 49.0 | 3.59e-01 | 96.9% | 55.5% |
| 1a22A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 44.0 | 3.54e-01 | 84.7% | 53.9% |
| 3p5pA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.54 | 48.0 | 3.44e-01 | 100.0% | 66.9% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.53 | 47.0 | 4.01e-01 | 99.0% | 88.8% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.53 | 36.0 | 3.81e-01 | 99.0% | 82.4% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.53 | 35.0 | 3.65e-01 | 88.8% | 74.2% |
| 3o7qA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 42.0 | 3.47e-01 | 100.0% | 46.9% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3971097 | 3562.1.1.8 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › IspA | 0.96 | 90.0 | 8.92e-01 | 100.0% | 94.0% |
| 4530585 | 5069.1.3.121 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › IspA | 0.90 | 83.0 | 8.04e-01 | 100.0% | 88.0% |
| 3685632 | 5073.1.2.12 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › PF30968 | 0.81 | 75.0 | 5.45e-01 | 100.0% | 54.8% |
| 3236866 | 1135.1.1.3 ↗ | a+b complex topology › Immune Mapped Protein 2 (IMP2) › Immune Mapped Protein 2 (IMP2) › Immune Mapped Protein 2 (IMP2) › CytochromB561_N | 0.74 | 52.0 | 5.29e-01 | 72.4% | 74.7% |
| 3285714 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.72 | 49.0 | 4.80e-01 | 74.5% | 64.8% |
| 3253767 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 51.0 | 4.36e-01 | 74.5% | 54.2% |
| 3956792 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.70 | 47.0 | 4.76e-01 | 74.5% | 69.4% |
| 3286816 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.69 | 51.0 | 4.69e-01 | 75.5% | 68.3% |
| 4988993 | 5086.1.1.231 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook | 0.69 | 50.0 | 4.22e-01 | 74.5% | 49.3% |
| 3729252 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 43.0 | 4.14e-01 | 74.5% | 57.4% |
| 3713451 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 54.0 | 4.87e-01 | 92.9% | 66.2% |
| 5039785 | 632.22.1.200 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 | 0.65 | 48.0 | 4.98e-01 | 88.8% | 80.9% |
| 3273941 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.65 | 59.0 | 4.44e-01 | 100.0% | 80.0% |
| 3517107 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.65 | 53.0 | 4.48e-01 | 100.0% | 54.1% |
| 3485310 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.63 | 53.0 | 4.70e-01 | 96.9% | 63.6% |
| 4329562 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.61 | 55.0 | 5.23e-01 | 100.0% | 92.2% |
| 5042044 | 4323.1.1.0 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C | 0.60 | 45.0 | 4.11e-01 | 78.6% | 79.2% |
| 3953329 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.60 | 52.0 | 4.11e-01 | 91.8% | 74.7% |
| 3247432 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.60 | 52.0 | 4.61e-01 | 96.9% | 66.2% |
| 3488158 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.59 | 46.0 | 4.31e-01 | 92.9% | 66.4% |
| 3499662 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 49.0 | 4.36e-01 | 96.9% | 65.2% |
| 3494901 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 49.0 | 4.32e-01 | 96.9% | 64.3% |
| 3793454 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.57 | 49.0 | 4.02e-01 | 100.0% | 52.0% |
| 4162650 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 44.0 | 3.63e-01 | 100.0% | 44.6% |
| 4951082 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 46.0 | 3.76e-01 | 99.0% | 47.9% |
| 5022752 | 7512.1.1.48 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › DUF3492 | 0.55 | 48.0 | 3.60e-01 | 98.0% | 43.1% |
| 3231048 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 47.0 | 4.15e-01 | 98.0% | 65.7% |
| 5011899 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.53 | 46.0 | 3.78e-01 | 100.0% | 83.2% |