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CAKLQF020000003.1__CAH1076231.1__SAMEA5780031_00714__00049

Bact-Vir

CAKLQF020000003.1__CAH1076231.1__SAMEA5780031_00714__00049

Identity

Kingdom:
phage

Quality

80.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-31_244-294
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.80 71.0 4.81e-01 97.3% 77.7%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 67.0 4.51e-01 90.7% 49.2%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.78 65.0 5.54e-01 90.7% 68.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 68.0 5.06e-01 100.0% 56.9%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 63.0 5.65e-01 90.7% 66.7%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.75 61.0 5.53e-01 85.3% 95.8%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.75 53.0 4.88e-01 86.7% 57.7%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 62.0 4.31e-01 92.0% 34.3%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.73 52.0 4.55e-01 74.7% 59.1%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.73 65.0 5.13e-01 98.7% 94.1%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 66.0 4.68e-01 100.0% 80.5%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 63.0 5.24e-01 100.0% 90.3%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.71 63.0 4.99e-01 97.3% 53.7%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 64.0 4.61e-01 100.0% 44.3%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.70 60.0 5.73e-01 92.0% 85.9%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.69 54.0 4.26e-01 82.7% 53.1%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 53.0 4.49e-01 82.7% 57.5%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.68 61.0 4.14e-01 100.0% 46.2%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 57.0 3.93e-01 92.0% 29.3%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 53.0 4.69e-01 92.0% 59.4%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 54.0 4.77e-01 88.0% 61.5%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.67 44.0 4.83e-01 98.7% 83.6%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 59.0 5.54e-01 97.3% 93.3%
4ackB00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.67 48.0 3.87e-01 89.3% 37.9%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.66 52.0 5.12e-01 85.3% 98.8%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 56.0 5.48e-01 92.0% 97.5%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.64 46.0 4.31e-01 74.7% 65.9%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 56.0 3.86e-01 100.0% 81.9%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 49.0 5.01e-01 85.3% 89.2%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.63 56.0 4.95e-01 97.3% 97.2%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.63 54.0 5.11e-01 98.7% 79.8%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.62 49.0 4.69e-01 82.7% 90.6%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 50.0 4.09e-01 90.7% 50.0%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 47.0 3.70e-01 80.0% 76.0%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.61 52.0 4.18e-01 100.0% 78.3%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.61 48.0 5.14e-01 84.0% 98.4%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 32.0 3.52e-01 70.7% 62.7%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 45.0 4.84e-01 80.0% 92.2%
2uuzB00 1.10.10.2020 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Host-nuclease inhibitor protein Gam 0.60 41.0 3.96e-01 70.7% 98.8%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.60 53.0 4.72e-01 97.3% 97.2%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.60 42.0 3.78e-01 74.7% 54.2%
4ysxC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.59 48.0 3.89e-01 90.7% 51.6%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.59 53.0 3.97e-01 98.7% 41.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.59 49.0 4.69e-01 93.3% 82.2%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.59 44.0 3.54e-01 84.0% 40.3%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.58 47.0 4.94e-01 86.7% 100.0%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.58 50.0 4.15e-01 93.3% 54.3%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 50.0 4.54e-01 98.7% 78.6%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.57 42.0 3.21e-01 78.7% 83.0%
2oyyA00 6.10.80.10 Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) 0.52 40.0 4.14e-01 84.0% 94.4%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3717860 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.84 75.0 7.01e-01 96.0% 88.9%
4937584 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.82 71.0 7.15e-01 90.7% 96.0%
3839085 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.82 60.0 5.39e-01 86.7% 57.0%
3940867 632.22.1.67 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › DUF842 0.79 62.0 5.70e-01 98.7% 66.3%
4989989 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.75 58.0 5.45e-01 81.3% 67.8%
3974187 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.74 57.0 5.37e-01 81.3% 67.8%
5023334 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.74 56.0 5.55e-01 81.3% 76.2%
4563317 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.73 56.0 5.56e-01 86.7% 76.2%
5043090 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.72 55.0 5.43e-01 81.3% 77.5%
3346986 3711.1.1.4 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 0.72 63.0 4.61e-01 98.7% 55.1%
3205388 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 62.0 4.28e-01 94.7% 65.5%
4928060 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.70 53.0 4.67e-01 84.0% 55.0%
3973899 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.70 59.0 4.77e-01 93.3% 96.6%
4984355 3843.1.1.1 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 0.70 60.0 5.54e-01 97.3% 73.7%
4115372 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 60.0 5.21e-01 93.3% 95.5%
4993050 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.68 61.0 4.43e-01 100.0% 83.3%
4174593 3922.1.1.248 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF25876 0.68 49.0 4.97e-01 76.0% 96.0%
329329 3814.1.1.1 alpha bundles › Uncharacterized protein GSU0061 › Uncharacterized protein GSU0061 › Uncharacterized protein GSU0061 › DUF3232 0.68 59.0 4.83e-01 94.7% 71.1%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 60.0 4.53e-01 100.0% 72.8%
3816176 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.67 59.0 5.28e-01 97.3% 71.4%
4026843 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.66 53.0 5.51e-01 86.7% 98.6%
5049284 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.66 58.0 5.01e-01 100.0% 89.2%
3602948 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.65 52.0 5.26e-01 86.7% 86.7%
5065235 101.1.2.738 alpha arrays › HTH › HTH › winged helix domain › Vir_act_alpha_C 0.64 57.0 4.22e-01 97.3% 41.6%
5081365 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.64 52.0 4.16e-01 90.7% 45.5%
3971056 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.63 46.0 3.92e-01 77.3% 84.2%
4270843 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 56.0 4.37e-01 100.0% 53.5%
3278037 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.61 47.0 3.47e-01 81.3% 31.8%
3729252 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 55.0 4.74e-01 100.0% 74.8%
3627873 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.60 49.0 4.94e-01 100.0% 89.3%
5083305 601.33.1.1 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.59 51.0 4.18e-01 97.3% 82.8%
3520309 198.1.1.1 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 0.53 40.0 4.00e-01 82.7% 81.3%
D2 high residues 311-395
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00512.32 best HisKA 51.2 1.40e-13 75.3% 98.5%
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.84 57.0 6.75e-01 72.9% 100.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 56.0 4.82e-01 75.3% 47.7%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 56.0 5.96e-01 78.8% 84.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.78 67.0 5.70e-01 96.5% 59.3%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 58.0 5.61e-01 78.8% 69.8%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 55.0 6.18e-01 74.1% 97.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.77 64.0 5.31e-01 92.9% 52.4%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.76 62.0 5.84e-01 88.2% 76.5%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 56.0 5.97e-01 83.5% 89.3%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.75 57.0 6.09e-01 80.0% 98.6%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.74 66.0 4.39e-01 100.0% 25.2%
3dmqA08 6.10.140.1500 Special › Helix non-globular › Helix Hairpins › 0.74 56.0 5.80e-01 87.1% 85.0%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 53.0 3.85e-01 74.1% 32.9%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.74 53.0 4.47e-01 82.4% 44.8%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 58.0 6.03e-01 84.7% 92.3%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 58.0 6.09e-01 90.6% 94.8%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 51.0 5.82e-01 72.9% 96.9%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.72 59.0 5.45e-01 87.1% 92.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 52.0 4.88e-01 80.0% 62.7%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 51.0 5.39e-01 100.0% 85.1%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 47.0 4.33e-01 70.6% 51.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.71 50.0 4.91e-01 72.9% 70.3%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 55.0 5.53e-01 83.5% 81.4%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 57.0 5.41e-01 91.8% 76.0%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.70 54.0 5.44e-01 83.5% 82.6%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.70 50.0 5.36e-01 78.8% 88.7%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 48.0 5.45e-01 76.5% 100.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 54.0 5.15e-01 83.5% 72.7%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.69 54.0 4.84e-01 84.7% 61.2%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 53.0 5.49e-01 83.5% 93.5%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 56.0 5.31e-01 90.6% 76.5%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.67 56.0 5.68e-01 94.1% 94.1%
1yf2A02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.67 58.0 5.48e-01 100.0% 86.0%
2ieqA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.67 52.0 5.22e-01 96.5% 81.8%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 56.0 5.29e-01 94.1% 78.6%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 51.0 5.23e-01 84.7% 88.0%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 49.0 5.26e-01 80.0% 100.0%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 57.0 4.05e-01 100.0% 34.2%
1kvkA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.65 42.0 3.51e-01 85.9% 37.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 46.0 4.38e-01 80.0% 63.4%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 48.0 4.93e-01 83.5% 86.4%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 44.0 4.74e-01 75.3% 91.5%
4biuE01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.61 52.0 5.04e-01 97.6% 86.7%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.60 44.0 4.83e-01 80.0% 100.0%
2lpeA01 6.10.140.1120 Special › Helix non-globular › Helix Hairpins › 0.59 42.0 4.41e-01 78.8% 83.3%
1yozA00 1.10.3200.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like 0.58 40.0 3.66e-01 74.1% 54.0%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4961508 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 69.0 7.28e-01 85.9% 97.3%
3929097 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.82 60.0 5.09e-01 75.3% 49.2%
3611632 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.82 67.0 6.37e-01 88.2% 78.0%
3296414 192.29.1.168 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF641 0.81 63.0 6.80e-01 87.1% 100.0%
5032752 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.80 55.0 5.57e-01 70.6% 71.8%
3947984 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 71.0 6.28e-01 100.0% 68.3%
3921192 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 67.0 6.02e-01 92.9% 67.0%
4809272 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.78 68.0 5.98e-01 100.0% 66.1%
5063748 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.78 54.0 5.25e-01 76.5% 64.9%
4363138 192.29.1.125 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cytochrom_C_asm 0.77 57.0 3.88e-01 76.5% 24.0%
5043412 1025.1.1.0 alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.77 60.0 5.39e-01 82.4% 63.5%
5028533 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 66.0 5.71e-01 98.8% 61.5%
3857880 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 65.0 5.38e-01 94.1% 53.8%
3974263 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.76 62.0 5.20e-01 87.1% 56.4%
3413114 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 48.0 5.45e-01 71.8% 84.6%
3744077 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.76 67.0 4.80e-01 100.0% 52.2%
3250231 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.76 69.0 5.06e-01 100.0% 43.3%
5042955 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.75 68.0 4.07e-01 100.0% 14.7%
3595103 3860.1.1.0 alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm 0.75 55.0 4.66e-01 83.5% 48.1%
3884746 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 63.0 5.39e-01 94.1% 57.8%
3596574 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.74 66.0 5.34e-01 100.0% 51.5%
3741801 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.74 64.0 5.64e-01 98.8% 64.8%
3802185 192.8.1.359 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF641 0.74 56.0 6.02e-01 87.1% 98.6%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 61.0 6.11e-01 90.6% 88.2%
5002671 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.73 66.0 5.36e-01 100.0% 86.9%
3628093 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.73 58.0 5.39e-01 83.5% 76.2%
4971990 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 66.0 5.07e-01 100.0% 45.7%
4177674 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.73 59.0 5.38e-01 85.9% 89.1%
3445025 174.1.1.2 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal 0.73 65.0 5.32e-01 98.8% 96.1%
3174178 632.22.1.153 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › AIP3 0.72 60.0 4.74e-01 92.9% 44.0%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.72 60.0 6.10e-01 90.6% 89.4%
3491418 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.72 56.0 5.94e-01 87.1% 94.7%
3487862 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.72 60.0 4.30e-01 96.5% 32.1%
3663959 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.71 63.0 5.46e-01 97.6% 66.2%
4967728 5058.1.1.100 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PsiE 0.71 63.0 5.28e-01 98.8% 64.8%
4010416 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.71 64.0 5.62e-01 100.0% 72.8%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.71 59.0 5.98e-01 91.8% 89.4%
3167298 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.71 63.0 5.91e-01 100.0% 81.9%
5050356 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.71 54.0 5.93e-01 80.0% 100.0%
4110261 3748.1.1.2 extended segments › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › 26S proteasome regulatory subunit RPN8/RPN11 C-terminal domain › CSN5_C 0.71 54.0 5.45e-01 83.5% 81.2%
2323907 212.1.1.24 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.71 60.0 4.36e-01 95.3% 34.4%
5064482 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 64.0 5.13e-01 100.0% 52.7%
3944006 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 64.0 5.58e-01 100.0% 71.2%
3350539 192.23.1.6 alpha bundles › Long alpha-hairpin › DUF683 › DUF683 › Med10 0.70 51.0 5.16e-01 80.0% 77.6%
3484742 3922.1.1.197 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp 0.70 54.0 5.48e-01 95.3% 83.5%
5044800 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.70 55.0 5.66e-01 100.0% 90.0%
4129922 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.69 54.0 5.13e-01 94.1% 72.0%
5057549 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.69 51.0 4.62e-01 89.4% 57.6%
3477418 4992.1.1.12 extended segments › RelB-like › RelB-like › RelB-like › LIN9_C 0.69 56.0 5.43e-01 88.2% 82.1%
3566029 3291.1.1.13 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Noelin-1 0.68 57.0 5.13e-01 95.3% 65.8%
3412574 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.68 59.0 5.21e-01 100.0% 68.5%
4984327 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.68 58.0 5.40e-01 94.1% 76.2%
4663913 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.68 54.0 4.36e-01 83.5% 52.3%
5062668 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.67 60.0 5.32e-01 100.0% 70.4%
3594486 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 59.0 5.27e-01 100.0% 69.2%
4474737 3711.1.1.44 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Med11 0.67 52.0 5.12e-01 84.7% 80.0%
3934599 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.67 49.0 4.66e-01 85.9% 64.8%
5040175 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.66 59.0 5.35e-01 100.0% 74.8%
3906810 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.65 57.0 4.90e-01 100.0% 67.9%
3849547 4992.1.1.25 extended segments › RelB-like › RelB-like › RelB-like › SHCBP_N 0.64 46.0 4.52e-01 87.1% 68.4%
4954894 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.64 50.0 4.43e-01 89.4% 56.2%
5049840 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.61 46.0 4.83e-01 84.7% 94.7%
D3 high residues 403-549
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02518.32 best HATPase_c 78.9 5.50e-22 74.8% 95.5%
D4 medium residues 44-113_132-150_188-243
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2mj6A00 3.30.450.250 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.67 39.0 4.88e-01 97.2% 93.3%
4jgpA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.57 36.0 4.42e-01 96.6% 100.0%
2mm0A00 2.10.70.110 Mainly Beta › Ribbon › Complement Module; domain 1 › 0.52 24.0 3.24e-01 89.7% 89.1%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2141651 913.1.1.5 few secondary structure elements › Hormone receptor domain (HRM, Pfam 02793) › Hormone receptor domain (HRM, Pfam 02793) › Hormone receptor domain (HRM, Pfam 02793) › PF29282 0.70 53.0 5.78e-01 100.0% 93.4%
1389170 223.1.1.38 a+b three layers › Profilin-like › sensor domains › sensor domains › DraK_HK_N 0.67 39.0 4.88e-01 97.2% 93.3%
5017303 223.8.1.0 a+b three layers › Profilin-like › LapD periplasmic domain › LapD periplasmic domain 0.62 39.0 4.70e-01 96.6% 98.9%
5002460 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.58 33.0 3.74e-01 93.8% 71.8%
3984458 223.1.1.110 a+b three layers › Profilin-like › sensor domains › sensor domains › PF30364 0.57 32.0 3.38e-01 93.8% 59.3%
3977347 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 32.0 2.95e-01 94.5% 42.1%
5045730 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.55 34.0 3.56e-01 95.9% 65.4%
3969103 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.55 31.0 3.48e-01 95.2% 70.8%
4078242 3008.1.1.0 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.54 31.0 3.64e-01 98.6% 80.0%
5045729 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.54 33.0 3.48e-01 95.9% 66.2%
5002347 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.52 32.0 3.42e-01 95.9% 68.8%
4950290 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.52 32.0 3.37e-01 95.9% 65.2%
3913337 11.1.1.97 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.50 23.0 2.68e-01 97.9% 55.2%