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CAKLQF020000003.1__CAH1076369.1__SAMEA5780031_00761__00095
Bact-VirCAKLQF020000003.1__CAH1076369.1__SAMEA5780031_00761__00095
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 389-446
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2aplA01 | 1.10.8.330 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.64 | 44.0 | 4.21e-01 | 93.1% | 61.8% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.62 | 48.0 | 4.44e-01 | 94.8% | 66.2% |
| 5svlA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.61 | 54.0 | 5.14e-01 | 100.0% | 94.1% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.61 | 44.0 | 4.72e-01 | 87.9% | 91.8% |
| 4kjmA02 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.59 | 38.0 | 3.92e-01 | 94.8% | 69.1% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.59 | 44.0 | 4.34e-01 | 93.1% | 75.4% |
| 6e1kA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 49.0 | 4.04e-01 | 96.6% | 72.3% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 44.0 | 4.04e-01 | 89.7% | 61.5% |
| 1uaaA02 | 1.10.10.160 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.58 | 39.0 | 3.58e-01 | 91.4% | 54.1% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.57 | 47.0 | 4.63e-01 | 93.1% | 90.5% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.57 | 49.0 | 3.89e-01 | 100.0% | 46.8% |
| 2jx4A01 | 6.10.140.460 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 35.0 | 3.79e-01 | 72.4% | 79.2% |
| 5tj5E00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.55 | 47.0 | 3.66e-01 | 100.0% | 57.2% |
| 1x0tA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.55 | 43.0 | 4.25e-01 | 86.2% | 83.6% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.55 | 41.0 | 4.04e-01 | 93.1% | 75.0% |
| 4n06A02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.54 | 46.0 | 3.07e-01 | 100.0% | 27.7% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.54 | 44.0 | 4.29e-01 | 93.1% | 90.6% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.53 | 43.0 | 2.65e-01 | 93.1% | 70.5% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.53 | 44.0 | 4.12e-01 | 93.1% | 75.3% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.53 | 40.0 | 3.87e-01 | 86.2% | 75.7% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.53 | 45.0 | 3.91e-01 | 96.6% | 62.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3978674 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.99 | 95.0 | 5.45e-01 | 100.0% | 13.1% |
| 5063936 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.98 | 93.0 | 5.37e-01 | 100.0% | 13.9% |
| 3586863 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.95 | 89.0 | 5.13e-01 | 100.0% | 13.6% |
| 3970388 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.94 | 85.0 | 4.94e-01 | 96.6% | 13.6% |
| 3606827 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.64 | 48.0 | 5.12e-01 | 89.7% | 96.0% |
| 3427989 | 1008.1.1.0 ↗ | alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain | 0.63 | 54.0 | 5.09e-01 | 96.6% | 81.4% |
| 3513342 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 50.0 | 3.46e-01 | 89.7% | 80.5% |
| 4014071 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 51.0 | 3.49e-01 | 94.8% | 77.0% |
| 1684842 | 1007.1.1.1 ↗ | alpha arrays › SopD C-terminal domain › SopD C-terminal domain › SopD C-terminal domain › SopD | 0.61 | 49.0 | 3.48e-01 | 100.0% | 28.8% |
| 4420136 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.58 | 43.0 | 4.13e-01 | 93.1% | 67.1% |
| 3503635 | 605.1.1.133 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › OST3_OST6 | 0.58 | 47.0 | 3.81e-01 | 91.4% | 75.8% |
| 2055366 | 622.1.1.2 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA | 0.58 | 46.0 | 4.19e-01 | 93.1% | 63.4% |
| 4937556 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.57 | 44.0 | 4.45e-01 | 94.8% | 85.0% |
| 3785108 | 4126.1.1.1 ↗ | a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › Pro_CA | 0.56 | 44.0 | 2.97e-01 | 86.2% | 30.0% |
| 3494616 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.56 | 45.0 | 4.00e-01 | 89.7% | 63.5% |
| 4944472 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.55 | 47.0 | 2.99e-01 | 98.3% | 60.4% |
| 3988228 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.55 | 46.0 | 2.95e-01 | 94.8% | 57.3% |
| 4987417 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.53 | 41.0 | 3.82e-01 | 86.2% | 65.3% |
| 4990614 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.53 | 46.0 | 3.00e-01 | 100.0% | 42.9% |
D2
medium
residues 12-111_319-366
Domain cluster:
rep: CAKLQF020000006.1__CAH1079699.1__SAMEA5780031_01362__00005__D16-102_309-349
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00860.27 best | Xan_ur_permease | 54.1 | 1.50e-14 | 60.1% | 20.3% |
| PF00860.27 | Xan_ur_permease | 48.1 | 9.90e-13 | 38.5% | 14.4% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.67 | 36.0 | 3.83e-01 | 89.2% | 58.6% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.61 | 48.0 | 3.33e-01 | 82.4% | 85.2% |
| 3feyA02 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 31.0 | 2.88e-01 | 92.6% | 35.9% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 43.0 | 3.79e-01 | 80.4% | 92.3% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.56 | 32.0 | 3.67e-01 | 93.2% | 75.0% |
| 3l6aA01 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 29.0 | 2.71e-01 | 97.3% | 38.4% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 42.0 | 3.54e-01 | 80.4% | 82.3% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.54 | 38.0 | 4.08e-01 | 70.9% | 100.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.52 | 27.0 | 3.54e-01 | 87.2% | 91.1% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.52 | 34.0 | 3.59e-01 | 85.1% | 74.0% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.51 | 33.0 | 3.98e-01 | 73.0% | 97.0% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.51 | 36.0 | 3.61e-01 | 72.3% | 76.0% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 40.0 | 3.67e-01 | 81.1% | 94.7% |
| 7fciA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.51 | 42.0 | 3.39e-01 | 89.2% | 77.2% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3978674 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.98 | 96.0 | 6.47e-01 | 100.0% | 80.5% |
| 3743827 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.98 | 95.0 | 6.24e-01 | 99.3% | 79.4% |
| 4020074 | 3226.1.1.0 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA | 0.97 | 92.0 | 6.09e-01 | 97.3% | 79.2% |
| 4964219 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.96 | 93.0 | 6.34e-01 | 99.3% | 78.8% |
| 3970388 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.95 | 92.0 | 6.30e-01 | 98.6% | 81.0% |
| 3978101 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.94 | 91.0 | 6.17e-01 | 98.6% | 77.9% |
| 5063936 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.94 | 91.0 | 6.25e-01 | 99.3% | 78.9% |
| 3282065 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.93 | 90.0 | 6.16e-01 | 98.6% | 81.0% |
| 3373143 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.93 | 91.0 | 5.97e-01 | 100.0% | 76.6% |
| 3586863 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.93 | 86.0 | 5.88e-01 | 95.3% | 76.8% |
| 4964714 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.93 | 88.0 | 5.89e-01 | 98.0% | 78.5% |
| 3804796 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.92 | 83.0 | 5.58e-01 | 92.6% | 74.6% |
| 3883105 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.92 | 89.0 | 5.86e-01 | 99.3% | 79.0% |
| 3215753 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.92 | 88.0 | 5.79e-01 | 98.6% | 76.4% |
| 5013775 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.91 | 87.0 | 5.95e-01 | 97.3% | 80.1% |
| 3293842 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.89 | 85.0 | 5.60e-01 | 99.3% | 72.7% |
| 3326296 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.88 | 82.0 | 5.50e-01 | 96.6% | 72.9% |
| 3816799 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.87 | 81.0 | 5.92e-01 | 97.3% | 84.3% |
| 4949782 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.85 | 82.0 | 5.65e-01 | 100.0% | 78.4% |
| 3976985 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.85 | 76.0 | 5.30e-01 | 93.9% | 81.7% |
| 3733301 | 3226.1.1.2 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Sulfate_transp | 0.69 | 63.0 | 4.44e-01 | 97.3% | 82.3% |
| 3174884 | 3226.1.1.2 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Sulfate_transp | 0.67 | 60.0 | 4.20e-01 | 97.3% | 81.7% |
| 4169514 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.60 | 50.0 | 4.64e-01 | 89.2% | 85.4% |
| 3942018 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 39.0 | 3.44e-01 | 94.6% | 45.0% |
| 4522145 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.59 | 51.0 | 4.79e-01 | 93.2% | 85.6% |
| 5065286 | 129.1.1.0 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.59 | 43.0 | 4.82e-01 | 87.8% | 97.4% |
| 5035390 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.58 | 43.0 | 4.19e-01 | 91.9% | 70.0% |
| 4975885 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.58 | 44.0 | 2.79e-01 | 79.1% | 70.4% |
| 5034312 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.57 | 42.0 | 4.77e-01 | 95.3% | 99.1% |
| 3694901 | 3921.1.1.3 ↗ | alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › GDT1 | 0.55 | 48.0 | 4.54e-01 | 94.6% | 83.9% |
| 4051719 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 29.0 | 2.99e-01 | 84.5% | 50.3% |
| 3440427 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 38.0 | 3.32e-01 | 73.6% | 89.3% |
| 3395533 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 41.0 | 3.66e-01 | 83.1% | 78.1% |
| 3949330 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 38.0 | 3.42e-01 | 80.4% | 85.9% |
| 3932315 | 601.3.1.17 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › TMEM120A-B | 0.50 | 36.0 | 3.14e-01 | 73.6% | 63.5% |
D3
medium
residues 112-154_284-318
Domain cluster:
representative
CATH (79)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.78 | 55.0 | 4.95e-01 | 96.2% | 53.8% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.75 | 57.0 | 5.68e-01 | 97.4% | 77.5% |
| 4mtxD00 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.74 | 53.0 | 4.92e-01 | 96.2% | 61.1% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.73 | 50.0 | 4.90e-01 | 94.9% | 64.4% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.73 | 56.0 | 5.10e-01 | 98.7% | 62.1% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 53.0 | 5.54e-01 | 94.9% | 84.5% |
| 2gl2B00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 50.0 | 4.44e-01 | 94.9% | 51.4% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 55.0 | 5.83e-01 | 96.2% | 95.6% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.70 | 44.0 | 4.28e-01 | 98.7% | 57.6% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.69 | 44.0 | 3.84e-01 | 100.0% | 43.6% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 47.0 | 4.85e-01 | 94.9% | 75.7% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.67 | 59.0 | 4.43e-01 | 96.2% | 77.1% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.67 | 46.0 | 4.50e-01 | 91.0% | 64.4% |
| 3crmA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.66 | 39.0 | 3.80e-01 | 73.1% | 54.8% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 61.0 | 4.07e-01 | 100.0% | 74.9% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.66 | 57.0 | 4.73e-01 | 96.2% | 94.2% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.65 | 46.0 | 5.11e-01 | 94.9% | 93.5% |
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 51.0 | 4.52e-01 | 91.0% | 59.5% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 53.0 | 5.37e-01 | 98.7% | 90.9% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.64 | 56.0 | 5.51e-01 | 93.6% | 90.2% |
| 3zbhA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 55.0 | 5.23e-01 | 96.2% | 80.0% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.64 | 56.0 | 5.40e-01 | 97.4% | 85.1% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.64 | 54.0 | 4.94e-01 | 96.2% | 72.0% |
| 3qavA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 47.0 | 3.89e-01 | 96.2% | 44.3% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.63 | 58.0 | 5.57e-01 | 98.7% | 88.6% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 56.0 | 3.90e-01 | 98.7% | 31.6% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.63 | 55.0 | 5.28e-01 | 98.7% | 83.3% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.63 | 46.0 | 4.23e-01 | 98.7% | 58.8% |
| 3ipiA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 53.0 | 3.64e-01 | 92.3% | 26.9% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 53.0 | 5.29e-01 | 96.2% | 87.8% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 58.0 | 4.66e-01 | 100.0% | 74.6% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 45.0 | 3.75e-01 | 92.3% | 43.2% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 47.0 | 4.85e-01 | 97.4% | 90.3% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.61 | 54.0 | 5.03e-01 | 97.4% | 88.7% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.61 | 53.0 | 4.59e-01 | 94.9% | 62.2% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.61 | 48.0 | 5.09e-01 | 88.5% | 97.1% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 54.0 | 3.86e-01 | 98.7% | 43.2% |
| 8b6jF01 | 1.10.287.20 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain | 0.61 | 38.0 | 4.05e-01 | 80.8% | 73.1% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 54.0 | 4.74e-01 | 97.4% | 75.0% |
| 4modA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.61 | 53.0 | 5.39e-01 | 98.7% | 97.4% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.60 | 53.0 | 3.47e-01 | 98.7% | 23.2% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.60 | 48.0 | 3.74e-01 | 98.7% | 38.8% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.60 | 53.0 | 5.16e-01 | 98.7% | 95.3% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 50.0 | 4.67e-01 | 92.3% | 90.6% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 52.0 | 4.82e-01 | 96.2% | 78.6% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 49.0 | 4.47e-01 | 97.4% | 68.9% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 51.0 | 4.70e-01 | 96.2% | 73.5% |
| 4xvxA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 52.0 | 4.25e-01 | 98.7% | 57.8% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.59 | 48.0 | 4.96e-01 | 96.2% | 95.9% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.59 | 52.0 | 4.09e-01 | 98.7% | 50.9% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.59 | 48.0 | 4.23e-01 | 91.0% | 60.3% |
| 3h1nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.59 | 45.0 | 3.94e-01 | 97.4% | 54.2% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.58 | 43.0 | 4.01e-01 | 96.2% | 61.6% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.58 | 48.0 | 4.93e-01 | 97.4% | 97.3% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 46.0 | 4.24e-01 | 94.9% | 66.3% |
| 1cqxA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 49.0 | 4.01e-01 | 96.2% | 83.3% |
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.57 | 44.0 | 3.66e-01 | 88.5% | 47.4% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.57 | 50.0 | 3.29e-01 | 96.2% | 23.6% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 34.0 | 3.32e-01 | 78.2% | 54.1% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.56 | 46.0 | 4.69e-01 | 96.2% | 95.9% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.56 | 50.0 | 4.94e-01 | 98.7% | 100.0% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 47.0 | 4.00e-01 | 97.4% | 54.8% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.56 | 35.0 | 3.42e-01 | 83.3% | 56.8% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.56 | 49.0 | 3.69e-01 | 98.7% | 53.3% |
| 2xq9A02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.56 | 43.0 | 3.68e-01 | 82.1% | 55.4% |
| 1kf6C00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.55 | 44.0 | 3.72e-01 | 94.9% | 51.5% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.55 | 48.0 | 4.47e-01 | 98.7% | 79.8% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 41.0 | 4.09e-01 | 78.2% | 80.0% |
| 4n21E00 | 1.10.287.210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 49.0 | 4.21e-01 | 98.7% | 62.8% |
| 1e1dA02 | 1.20.1270.20 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 39.0 | 3.88e-01 | 98.7% | 72.6% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.54 | 43.0 | 4.40e-01 | 93.6% | 90.8% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.54 | 45.0 | 4.67e-01 | 94.9% | 100.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.54 | 39.0 | 3.83e-01 | 91.0% | 71.8% |
| 6jpaE00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.53 | 46.0 | 3.63e-01 | 97.4% | 85.8% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.65e-01 | 89.7% | 53.1% |
| 3tbiB02 | 6.10.140.1670 | Special › Helix non-globular › Helix Hairpins › | 0.53 | 45.0 | 4.22e-01 | 96.2% | 79.0% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 45.0 | 3.94e-01 | 97.4% | 63.6% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.52 | 43.0 | 3.84e-01 | 89.7% | 62.7% |
| 3nb0B03 | 6.10.260.10 | Special › Helix non-globular › F1FO ATP Synthase › | 0.50 | 42.0 | 4.12e-01 | 97.4% | 85.7% |
ECOD (65)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3447097 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.71 | 56.0 | 5.00e-01 | 97.4% | 60.0% |
| 5055566 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.70 | 54.0 | 4.71e-01 | 98.7% | 55.7% |
| 3923555 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 48.0 | 4.08e-01 | 96.2% | 44.6% |
| 2749857 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.68 | 59.0 | 3.86e-01 | 97.4% | 24.7% |
| 3200160 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.67 | 55.0 | 4.90e-01 | 97.4% | 62.7% |
| 5018636 | 605.1.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_2 | 0.67 | 56.0 | 5.87e-01 | 94.9% | 100.0% |
| 3346014 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.66 | 55.0 | 3.71e-01 | 97.4% | 24.5% |
| 3961296 | 150.5.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 | 0.66 | 58.0 | 5.41e-01 | 98.7% | 78.7% |
| 3962167 | 3718.1.1.0 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT | 0.65 | 33.0 | 3.45e-01 | 98.7% | 50.0% |
| 3477269 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.65 | 59.0 | 4.62e-01 | 98.7% | 54.8% |
| 3212520 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.65 | 60.0 | 4.75e-01 | 100.0% | 84.0% |
| 3685299 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 56.0 | 4.84e-01 | 100.0% | 61.7% |
| 3616483 | 3755.3.1.280 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Spindly | 0.64 | 56.0 | 3.69e-01 | 97.4% | 24.7% |
| 3564399 | 3755.3.1.282 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 | 0.64 | 58.0 | 5.08e-01 | 98.7% | 70.4% |
| 3441963 | 605.1.1.222 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF4220 | 0.64 | 57.0 | 4.93e-01 | 96.2% | 67.8% |
| 3519972 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.64 | 57.0 | 5.43e-01 | 96.2% | 83.3% |
| 5050578 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.63 | 58.0 | 5.78e-01 | 98.7% | 97.5% |
| 3479808 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 53.0 | 4.21e-01 | 89.7% | 85.9% |
| 3626769 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.63 | 56.0 | 5.37e-01 | 96.2% | 83.3% |
| 3857357 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.63 | 57.0 | 5.07e-01 | 98.7% | 72.7% |
| 5014330 | 148.1.3.402 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Rad50_zn_hook | 0.63 | 56.0 | 5.01e-01 | 98.7% | 70.9% |
| 3960437 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 53.0 | 4.07e-01 | 96.2% | 41.8% |
| 4230460 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.63 | 56.0 | 3.21e-01 | 97.4% | 37.1% |
| 3944006 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.63 | 57.0 | 4.81e-01 | 98.7% | 63.2% |
| 3993457 | 601.1.2.90 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Not3 | 0.63 | 57.0 | 4.67e-01 | 100.0% | 72.9% |
| 3229078 | 150.5.1.124 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › Claudin_3 | 0.63 | 53.0 | 4.94e-01 | 96.2% | 74.7% |
| 3961947 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.63 | 57.0 | 4.47e-01 | 98.7% | 50.3% |
| 3553833 | 5086.1.1.102 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PTHB1_hp | 0.63 | 57.0 | 4.20e-01 | 98.7% | 41.1% |
| 4974229 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.63 | 57.0 | 4.29e-01 | 98.7% | 45.1% |
| 3640760 | 3291.1.1.17 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF202 | 0.63 | 57.0 | 5.07e-01 | 100.0% | 89.1% |
| 4010416 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.62 | 56.0 | 4.77e-01 | 98.7% | 62.4% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.62 | 56.0 | 4.38e-01 | 98.7% | 51.2% |
| 3717072 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.62 | 56.0 | 4.51e-01 | 98.7% | 54.5% |
| 3396860 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.62 | 55.0 | 4.51e-01 | 97.4% | 88.6% |
| 3541873 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.62 | 56.0 | 4.55e-01 | 98.7% | 65.7% |
| 3541698 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.62 | 56.0 | 4.54e-01 | 100.0% | 91.0% |
| 3876590 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.62 | 47.0 | 4.66e-01 | 97.4% | 77.6% |
| 3755586 | 3291.1.1.118 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF9 | 0.62 | 56.0 | 4.54e-01 | 98.7% | 55.7% |
| 3448091 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 54.0 | 4.70e-01 | 96.2% | 64.9% |
| 3945620 | 5086.1.1.85 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA | 0.61 | 54.0 | 5.19e-01 | 98.7% | 84.4% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 54.0 | 4.21e-01 | 97.4% | 47.3% |
| 3516641 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 55.0 | 4.32e-01 | 98.7% | 48.8% |
| 3478220 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.61 | 53.0 | 4.86e-01 | 96.2% | 86.0% |
| 3988260 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.60 | 54.0 | 3.53e-01 | 98.7% | 42.5% |
| 3635376 | 3755.3.1.298 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING | 0.60 | 54.0 | 4.45e-01 | 98.7% | 60.7% |
| 3574255 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.60 | 53.0 | 4.42e-01 | 97.4% | 56.3% |
| 3642338 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.60 | 50.0 | 5.13e-01 | 97.4% | 97.3% |
| 4027771 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.60 | 52.0 | 3.80e-01 | 96.2% | 36.2% |
| 3781350 | 5041.1.1.20 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › PF26669 | 0.60 | 53.0 | 4.60e-01 | 98.7% | 70.8% |
| 4417765 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 53.0 | 4.45e-01 | 98.7% | 64.6% |
| 4946656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 51.0 | 4.40e-01 | 98.7% | 61.7% |
| 3745853 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.59 | 51.0 | 3.89e-01 | 96.2% | 56.2% |
| 2674763 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.59 | 48.0 | 4.95e-01 | 97.4% | 96.0% |
| 4476621 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.58 | 52.0 | 4.92e-01 | 100.0% | 87.4% |
| 3913300 | 3755.3.1.303 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A_4th | 0.58 | 50.0 | 4.07e-01 | 96.2% | 96.0% |
| 3995294 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.58 | 50.0 | 4.34e-01 | 97.4% | 61.6% |
| 3489794 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.58 | 50.0 | 4.02e-01 | 96.2% | 80.7% |
| 3801787 | 604.5.1.39 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF26581 | 0.58 | 50.0 | 4.18e-01 | 97.4% | 57.8% |
| 4027404 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.57 | 49.0 | 4.62e-01 | 97.4% | 97.9% |
| 4950969 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.56 | 50.0 | 3.07e-01 | 98.7% | 28.1% |
| 5069235 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 48.0 | 3.70e-01 | 97.4% | 43.3% |
| 3794016 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.55 | 47.0 | 3.32e-01 | 96.2% | 31.0% |
| 3344715 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 47.0 | 3.37e-01 | 97.4% | 34.3% |
| 4589685 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.52 | 39.0 | 3.70e-01 | 100.0% | 66.3% |
| 3719486 | 2006.1.1.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.52 | 46.0 | 3.21e-01 | 98.7% | 66.7% |
D4
medium
residues 155-232_254-283_367-380
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00860.27 best | Xan_ur_permease | 49.4 | 4.10e-13 | 66.4% | 20.8% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 37.0 | 4.48e-01 | 89.3% | 89.9% |
| 1l3pA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.62 | 36.0 | 3.94e-01 | 88.5% | 67.6% |
| 1e3pA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.60 | 35.0 | 4.06e-01 | 84.4% | 81.9% |
| 4aidA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.59 | 34.0 | 3.99e-01 | 86.1% | 84.1% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.58 | 37.0 | 4.44e-01 | 82.8% | 100.0% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.56 | 38.0 | 4.23e-01 | 79.5% | 88.7% |
| 1xvpB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.53 | 37.0 | 3.02e-01 | 98.4% | 36.6% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.52 | 37.0 | 3.87e-01 | 85.2% | 80.7% |
| 1yowA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.52 | 37.0 | 3.03e-01 | 100.0% | 39.6% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 29.0 | 3.16e-01 | 85.2% | 65.3% |
| 4n1yB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 37.0 | 3.07e-01 | 100.0% | 41.0% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 28.0 | 3.51e-01 | 75.4% | 89.3% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3978674 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.99 | 97.0 | 6.26e-01 | 100.0% | 51.4% |
| 3970388 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.94 | 92.0 | 6.00e-01 | 100.0% | 52.4% |
| 4964219 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.94 | 91.0 | 5.92e-01 | 100.0% | 50.9% |
| 3282065 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.92 | 89.0 | 5.84e-01 | 100.0% | 52.6% |
| 5013775 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.91 | 87.0 | 5.74e-01 | 100.0% | 52.9% |
| 3586863 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.90 | 86.0 | 5.67e-01 | 100.0% | 50.8% |
| 4280813 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.89 | 85.0 | 5.62e-01 | 100.0% | 53.7% |
| 3978101 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.88 | 84.0 | 5.54e-01 | 100.0% | 50.8% |
| 3255293 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.84 | 81.0 | 5.27e-01 | 100.0% | 48.6% |
| 3976985 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.84 | 79.0 | 5.29e-01 | 100.0% | 52.9% |
| 4680947 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.64 | 39.0 | 4.34e-01 | 84.4% | 76.8% |
| 2766590 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 38.0 | 4.13e-01 | 83.6% | 72.4% |
| 4436943 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 37.0 | 4.42e-01 | 82.8% | 88.7% |
| 4498171 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.63 | 37.0 | 4.57e-01 | 83.6% | 96.0% |
| 4226337 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.62 | 37.0 | 4.37e-01 | 83.6% | 88.7% |
| 4433075 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.62 | 38.0 | 4.28e-01 | 84.4% | 81.1% |
| 4143595 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.61 | 36.0 | 4.06e-01 | 84.4% | 75.8% |
| 4595954 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.60 | 37.0 | 4.24e-01 | 82.8% | 85.9% |
| 4105842 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.60 | 36.0 | 4.12e-01 | 84.4% | 80.0% |
| 4988623 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.60 | 28.0 | 2.19e-01 | 100.0% | 20.0% |
| 4429233 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.59 | 35.0 | 4.04e-01 | 90.2% | 82.4% |
| 4588041 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.59 | 37.0 | 4.23e-01 | 88.5% | 85.6% |
| 4550256 | 604.12.1.76 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › IspA | 0.58 | 31.0 | 3.82e-01 | 74.6% | 82.7% |
| 5009131 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 28.0 | 2.52e-01 | 72.1% | 33.3% |
| 5047072 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 28.0 | 2.56e-01 | 100.0% | 35.0% |
| 4116078 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 35.0 | 4.26e-01 | 79.5% | 97.3% |
| 3499344 | 3914.1.1.2 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer | 0.58 | 44.0 | 2.62e-01 | 78.7% | 39.1% |
| 4120292 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 35.0 | 4.17e-01 | 82.0% | 92.5% |
| 4197877 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.57 | 35.0 | 3.83e-01 | 90.2% | 74.0% |
| 4594465 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.57 | 36.0 | 4.00e-01 | 87.7% | 82.1% |
| 4617287 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.56 | 34.0 | 3.87e-01 | 84.4% | 81.1% |
| 3667663 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.56 | 43.0 | 4.00e-01 | 100.0% | 63.9% |
| 3771070 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.55 | 43.0 | 4.05e-01 | 100.0% | 66.5% |
| 4027154 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.55 | 37.0 | 4.08e-01 | 78.7% | 84.0% |
| 3572533 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 40.0 | 3.15e-01 | 78.7% | 71.3% |
| 4611743 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.54 | 36.0 | 4.05e-01 | 83.6% | 92.2% |
| 3563871 | 603.1.1.121 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821 | 0.53 | 44.0 | 4.51e-01 | 88.5% | 98.3% |
| 4932749 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 37.0 | 3.16e-01 | 72.1% | 64.3% |
| 5065057 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 29.0 | 2.65e-01 | 100.0% | 43.2% |
| 3974204 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.50 | 31.0 | 3.14e-01 | 85.2% | 60.0% |
| 3972478 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.50 | 33.0 | 3.35e-01 | 78.7% | 66.4% |