Back to structures

CAKLQF020000003.1__CAH1076441.1__SAMEA5780031_00785__00119

Bact-Vir

CAKLQF020000003.1__CAH1076441.1__SAMEA5780031_00785__00119

Identity

Kingdom:
phage

Quality

85.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 39-151_303-347
PDB
Domain cluster: representative
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.86 62.0 6.59e-01 74.7% 100.0%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 45.0 5.01e-01 95.6% 68.3%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.81 46.0 4.49e-01 99.4% 52.4%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.80 44.0 5.36e-01 95.6% 82.5%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.79 73.0 6.95e-01 98.7% 96.2%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.79 46.0 4.55e-01 100.0% 55.5%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.78 53.0 4.93e-01 100.0% 55.9%
5mawD00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.77 70.0 5.84e-01 96.2% 82.7%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 50.0 4.31e-01 100.0% 43.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 53.0 5.02e-01 100.0% 61.2%
2iakA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 52.0 4.90e-01 71.5% 59.9%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 53.0 4.82e-01 100.0% 59.5%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.72 59.0 6.04e-01 88.0% 100.0%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.71 50.0 5.57e-01 71.5% 92.0%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 44.0 3.63e-01 100.0% 36.3%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.71 51.0 5.44e-01 74.1% 99.3%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 45.0 3.77e-01 85.4% 39.5%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.70 51.0 4.78e-01 74.7% 74.9%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.70 47.0 4.24e-01 99.4% 50.7%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.69 57.0 4.75e-01 85.4% 59.6%
4ecgA00 1.20.1420.20 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif 0.69 56.0 4.18e-01 84.2% 51.9%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 39.0 4.56e-01 92.4% 79.4%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 4.65e-01 98.1% 64.2%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 54.0 5.80e-01 100.0% 93.5%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.67 49.0 5.09e-01 100.0% 80.1%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.67 50.0 4.73e-01 76.6% 76.6%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 45.0 3.83e-01 100.0% 42.2%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 35.0 4.66e-01 91.1% 96.3%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.27e-01 70.3% 80.7%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.65 50.0 5.05e-01 100.0% 78.3%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 51.0 4.46e-01 100.0% 56.3%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 31.0 3.73e-01 88.0% 66.1%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 50.0 4.97e-01 100.0% 79.5%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.62 44.0 4.95e-01 72.2% 100.0%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 49.0 4.13e-01 100.0% 49.2%
4gc0A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 43.0 3.83e-01 70.9% 61.1%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 42.0 3.62e-01 89.9% 45.6%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.61 49.0 3.83e-01 85.4% 87.9%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.61 51.0 4.36e-01 99.4% 56.4%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 52.0 5.24e-01 100.0% 89.9%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.60 30.0 4.17e-01 82.3% 100.0%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 53.0 4.75e-01 100.0% 69.3%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 34.0 3.83e-01 72.2% 71.1%
1yc9A01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.59 54.0 4.24e-01 100.0% 48.0%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.59 53.0 4.10e-01 100.0% 46.5%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 45.0 4.04e-01 100.0% 58.9%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 55.0 4.49e-01 100.0% 69.3%
6o0aA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 27.0 2.78e-01 95.6% 44.3%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 50.0 4.33e-01 100.0% 61.8%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.57 54.0 4.59e-01 100.0% 66.9%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.55 51.0 4.05e-01 99.4% 100.0%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 51.0 4.57e-01 100.0% 79.4%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 46.0 4.20e-01 100.0% 68.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 49.0 4.28e-01 100.0% 66.1%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.54 38.0 4.11e-01 71.5% 89.5%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 44.0 3.80e-01 100.0% 61.4%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4505320 601.4.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH 0.83 72.0 6.88e-01 91.1% 93.3%
3289173 601.1.1.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CHASE3 0.82 65.0 6.53e-01 82.9% 100.0%
5005480 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 46.0 4.51e-01 100.0% 52.0%
3949246 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.79 63.0 6.23e-01 82.3% 100.0%
4959549 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.79 73.0 6.89e-01 96.8% 98.9%
3975942 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.79 59.0 6.49e-01 76.6% 100.0%
3168460 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.78 53.0 3.31e-01 100.0% 14.2%
3695585 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 52.0 4.67e-01 100.0% 51.7%
3970019 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.77 56.0 4.84e-01 100.0% 50.4%
4526671 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.76 48.0 4.05e-01 96.8% 40.0%
3318681 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 54.0 4.30e-01 100.0% 40.7%
4939828 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.73 53.0 4.05e-01 100.0% 34.9%
3482286 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 56.0 5.17e-01 100.0% 63.0%
3744077 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.73 45.0 3.78e-01 82.9% 38.0%
3933045 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 42.0 3.94e-01 99.4% 47.6%
3738472 4177.1.1.9 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom 0.72 45.0 3.92e-01 100.0% 42.1%
3831567 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 51.0 4.97e-01 100.0% 67.6%
5079565 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 56.0 5.44e-01 100.0% 74.3%
3477269 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.70 55.0 5.57e-01 100.0% 81.9%
4974450 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.70 51.0 4.98e-01 100.0% 68.0%
3793986 604.7.1.7 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Mitofilin 0.70 45.0 4.87e-01 96.8% 76.3%
3923558 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 55.0 5.20e-01 100.0% 70.3%
3915989 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.69 50.0 3.10e-01 100.0% 14.5%
3239816 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.68 52.0 4.80e-01 100.0% 62.5%
4276314 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 52.0 4.64e-01 100.0% 56.8%
3207548 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 52.0 5.55e-01 100.0% 88.6%
3698277 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 47.0 4.68e-01 100.0% 68.8%
4396660 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 52.0 4.59e-01 100.0% 55.2%
3239971 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 53.0 4.58e-01 100.0% 55.2%
3165834 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.67 64.0 5.29e-01 100.0% 70.4%
4516566 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 50.0 4.71e-01 98.1% 64.2%
4345467 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.67 51.0 3.54e-01 100.0% 26.7%
3182496 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.67 51.0 3.78e-01 100.0% 33.3%
3238457 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.67 47.0 4.16e-01 71.5% 61.2%
3781506 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.66 54.0 5.51e-01 100.0% 86.5%
5056871 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.66 55.0 4.28e-01 100.0% 43.9%
3692808 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.66 46.0 4.07e-01 71.5% 67.4%
3187178 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.66 53.0 4.96e-01 100.0% 68.7%
3779488 3755.4.1.69 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF28341 0.65 51.0 4.72e-01 100.0% 65.5%
3628737 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 48.0 4.20e-01 100.0% 51.9%
4982498 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 56.0 3.71e-01 100.0% 24.1%
3239667 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.64 60.0 3.82e-01 100.0% 55.3%
3988263 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 47.0 4.52e-01 98.1% 67.4%
3919840 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.64 52.0 4.62e-01 100.0% 61.4%
2081472 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.64 56.0 5.44e-01 100.0% 85.3%
4211798 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.63 55.0 5.30e-01 100.0% 82.8%
4674585 5039.1.1.1 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 0.62 47.0 4.38e-01 79.1% 68.5%
3760483 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 47.0 4.44e-01 78.5% 100.0%
4966374 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 51.0 4.96e-01 100.0% 78.3%
4029164 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.62 50.0 4.30e-01 100.0% 54.4%
4001186 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 55.0 5.12e-01 100.0% 77.4%
3726691 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.61 46.0 4.01e-01 77.2% 67.2%
4676629 3755.3.1.290 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PPI_helical 0.61 50.0 4.33e-01 100.0% 58.3%
4018104 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 54.0 4.31e-01 100.0% 50.2%
3598025 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.61 46.0 4.48e-01 97.5% 71.8%
4230460 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.61 54.0 3.41e-01 100.0% 20.6%
4028552 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 55.0 4.66e-01 100.0% 61.6%
5082486 3834.1.1.0 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.60 57.0 3.87e-01 100.0% 33.5%
4943562 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.60 54.0 4.92e-01 100.0% 73.7%
4471073 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.59 55.0 4.03e-01 100.0% 41.1%
4030374 2004.1.1.36 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynamin_N 0.59 50.0 3.59e-01 96.2% 32.0%
3880326 4177.2.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.59 49.0 3.97e-01 100.0% 47.2%
5079778 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 53.0 3.72e-01 100.0% 32.7%
5014331 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.59 55.0 3.47e-01 100.0% 21.1%
3385272 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.59 54.0 3.33e-01 100.0% 63.7%
3368865 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 54.0 5.17e-01 99.4% 100.0%
5024408 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.59 56.0 5.27e-01 100.0% 95.1%
3599499 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 48.0 4.96e-01 100.0% 90.7%
3599997 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 54.0 3.35e-01 100.0% 51.7%
3965792 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.58 55.0 4.47e-01 100.0% 100.0%
5002671 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.58 55.0 5.52e-01 100.0% 98.8%
4428524 2004.1.1.567 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 0.58 54.0 3.39e-01 100.0% 28.2%
3727274 3758.1.1.69 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › PF30554 0.58 51.0 4.44e-01 100.0% 63.0%
3346133 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 51.0 4.58e-01 100.0% 68.8%
3832457 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.57 51.0 4.40e-01 100.0% 63.0%
3894262 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.57 48.0 3.82e-01 100.0% 45.6%
5002102 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 54.0 5.29e-01 100.0% 98.8%
3883526 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.57 46.0 3.67e-01 100.0% 44.1%
3889547 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 53.0 4.94e-01 98.7% 93.2%
3410024 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 53.0 4.37e-01 100.0% 70.9%
3908132 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 52.0 4.40e-01 99.4% 63.8%
4001188 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 53.0 3.75e-01 100.0% 68.3%
5009131 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 51.0 5.08e-01 98.7% 98.8%
4998236 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.55 49.0 3.49e-01 100.0% 33.2%
3746558 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 43.0 3.91e-01 100.0% 61.9%
4082395 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 51.0 4.87e-01 100.0% 99.4%
4139499 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.54 51.0 3.41e-01 100.0% 31.0%
4963648 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.54 50.0 3.48e-01 100.0% 36.9%
4259085 3755.4.1.66 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal 0.52 48.0 3.90e-01 100.0% 92.4%
3516576 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 42.0 3.79e-01 85.4% 96.2%
4980165 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 48.0 3.45e-01 100.0% 40.5%
3170937 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.50 44.0 3.62e-01 98.7% 53.5%
4960856 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 39.0 3.70e-01 82.3% 68.9%
D2 medium residues 152-189_282-302
PDB
Domain cluster: representative
D3 medium residues 190-281
PDB
Domain cluster: representative
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.83 71.0 6.40e-01 98.9% 68.9%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.83 59.0 6.07e-01 95.7% 77.9%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 61.0 6.67e-01 94.6% 97.3%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 62.0 6.73e-01 98.9% 98.7%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.81 50.0 5.85e-01 70.7% 87.9%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 50.0 6.02e-01 72.8% 96.8%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.78 65.0 6.04e-01 98.9% 72.6%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.77 64.0 6.06e-01 100.0% 74.5%
1zzpA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.76 58.0 5.49e-01 97.8% 67.9%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.76 58.0 4.80e-01 100.0% 46.0%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.76 64.0 5.39e-01 100.0% 56.5%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.75 62.0 5.53e-01 95.7% 64.0%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.75 56.0 5.04e-01 100.0% 57.0%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 66.0 6.01e-01 100.0% 73.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.74 56.0 5.64e-01 89.1% 80.2%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 68.0 5.25e-01 100.0% 51.3%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 52.0 4.41e-01 72.8% 63.3%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 52.0 5.13e-01 73.9% 72.4%
1kqfC00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.73 54.0 3.99e-01 77.2% 34.7%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.73 51.0 4.30e-01 72.8% 91.1%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 51.0 3.67e-01 72.8% 33.1%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.72 66.0 5.06e-01 100.0% 51.0%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.71 64.0 5.35e-01 98.9% 64.5%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.71 64.0 5.25e-01 98.9% 60.2%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 61.0 4.77e-01 100.0% 45.1%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 49.0 4.02e-01 71.7% 70.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 57.0 5.74e-01 100.0% 91.4%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.68 53.0 4.40e-01 100.0% 47.3%
3lomA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.68 55.0 3.89e-01 97.8% 28.5%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 60.0 5.48e-01 100.0% 82.8%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.66 60.0 5.30e-01 100.0% 74.8%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 60.0 5.44e-01 100.0% 86.0%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 51.0 5.14e-01 97.8% 85.7%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 58.0 5.11e-01 100.0% 69.4%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.64 57.0 4.74e-01 100.0% 92.7%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 57.0 5.14e-01 100.0% 80.2%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 47.0 4.37e-01 98.9% 61.5%
3h1nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 53.0 4.90e-01 97.8% 82.5%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 51.0 5.16e-01 94.6% 95.7%
1jvmB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 42.0 4.12e-01 71.7% 90.0%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.59 52.0 4.66e-01 100.0% 90.2%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.59 52.0 4.22e-01 98.9% 89.4%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.59 52.0 4.28e-01 98.9% 62.7%
2pvqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 47.0 4.54e-01 97.8% 78.3%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 50.0 4.64e-01 98.9% 93.2%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 52.0 3.71e-01 100.0% 36.7%
4mo7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 49.0 4.32e-01 100.0% 96.5%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 49.0 4.59e-01 100.0% 80.4%
3fhnA04 1.20.58.670 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D 0.54 45.0 4.10e-01 95.7% 75.6%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.53 45.0 4.56e-01 92.4% 100.0%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.53 43.0 4.43e-01 88.0% 98.8%
5gmkZ01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 43.0 3.26e-01 91.3% 81.0%
5domA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.51 35.0 3.62e-01 92.4% 73.3%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 43.0 3.61e-01 100.0% 94.2%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2875501 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.92 88.0 7.59e-01 100.0% 69.2%
3966166 601.4.1.4 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PilJ 0.87 79.0 6.94e-01 100.0% 68.5%
3962012 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 70.0 6.99e-01 100.0% 88.4%
3725161 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.79 66.0 6.11e-01 100.0% 71.3%
4020563 601.16.1.3 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C 0.76 62.0 5.48e-01 100.0% 61.5%
54287 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.75 65.0 5.99e-01 100.0% 73.9%
4118417 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.75 69.0 6.10e-01 98.9% 72.3%
3968997 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 48.0 4.23e-01 71.7% 45.4%
4387552 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.75 64.0 6.61e-01 96.7% 98.8%
3976632 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.74 53.0 4.36e-01 72.8% 74.0%
3832341 601.1.2.3 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › GCIP_C 0.74 59.0 4.62e-01 100.0% 40.5%
3462043 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 62.0 6.28e-01 100.0% 92.2%
4133341 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.74 68.0 6.17e-01 100.0% 77.5%
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 68.0 6.40e-01 100.0% 86.4%
4038749 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 66.0 6.14e-01 97.8% 80.0%
4948609 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.73 62.0 6.34e-01 100.0% 94.4%
3653783 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 60.0 5.07e-01 100.0% 53.5%
4286256 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 51.0 4.52e-01 72.8% 78.5%
3610860 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 66.0 5.71e-01 100.0% 65.7%
3920125 3755.3.1.450 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Uso1_p115_C 0.72 51.0 3.89e-01 72.8% 86.2%
5051764 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.72 66.0 5.49e-01 100.0% 91.6%
3727421 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 66.0 5.39e-01 98.9% 62.5%
4932148 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.72 51.0 4.53e-01 72.8% 69.6%
3221955 601.25.1.0 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain 0.72 62.0 5.21e-01 98.9% 56.5%
4999868 604.1.1.264 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Oxidored_q2 0.72 60.0 6.08e-01 100.0% 93.3%
3706526 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 50.0 4.19e-01 72.8% 54.0%
3491815 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.71 62.0 6.25e-01 100.0% 94.7%
3565045 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 61.0 5.14e-01 93.5% 62.0%
2877634 601.2.1.6 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_B562 0.71 58.0 5.30e-01 100.0% 67.5%
3494149 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.70 64.0 5.23e-01 100.0% 59.4%
3787128 109.4.1.654 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFB6 0.70 59.0 4.38e-01 100.0% 36.5%
3732719 601.1.1.25 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.70 63.0 5.57e-01 100.0% 68.1%
3948872 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 48.0 4.22e-01 70.7% 50.0%
3192001 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.69 61.0 5.39e-01 100.0% 68.6%
3670976 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.69 62.0 5.33e-01 100.0% 73.1%
3418792 3755.3.1.400 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A_C 0.69 62.0 5.16e-01 100.0% 87.5%
54407 601.2.1.0 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.69 56.0 5.32e-01 97.8% 74.5%
5076088 5039.1.1.0 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.69 64.0 5.56e-01 100.0% 71.1%
4200809 603.1.1.9 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › COG2p_C 0.69 60.0 5.00e-01 100.0% 55.6%
4937575 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 60.0 6.13e-01 96.7% 96.7%
2323994 604.37.1.0 alpha bundles › Spectrin repeat-like › Legionella effector Lem22 › Legionella effector Lem22 0.69 58.0 5.86e-01 100.0% 93.3%
3323342 604.12.1.100 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › FKS1_dom1 0.69 54.0 3.69e-01 100.0% 23.6%
3267624 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.68 61.0 5.39e-01 100.0% 71.9%
3171851 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.68 61.0 5.06e-01 100.0% 61.3%
3898384 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 57.0 5.10e-01 100.0% 65.4%
3481122 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 60.0 5.88e-01 100.0% 99.0%
3478117 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.67 59.0 4.73e-01 100.0% 52.1%
3377360 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 60.0 5.45e-01 97.8% 100.0%
4996069 604.10.1.0 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.67 56.0 5.71e-01 100.0% 94.4%
3964486 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 46.0 3.74e-01 70.7% 40.6%
3560229 3291.1.1.230 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › TBCA_PH 0.66 56.0 4.85e-01 92.4% 100.0%
4446434 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 45.0 3.88e-01 70.7% 46.4%
3507250 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 57.0 5.55e-01 100.0% 86.7%
3313934 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.65 60.0 6.00e-01 100.0% 96.8%
3884762 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 57.0 4.79e-01 100.0% 61.3%
3311689 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.64 58.0 5.06e-01 100.0% 70.0%
3715891 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 44.0 3.58e-01 70.7% 43.0%
4058767 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.63 55.0 4.81e-01 100.0% 63.6%
3221921 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.62 44.0 4.28e-01 72.8% 73.0%
3654589 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.62 53.0 5.41e-01 97.8% 97.8%
3801875 604.1.1.135 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF155 0.62 54.0 4.00e-01 100.0% 95.7%
3358939 604.3.1.11 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 0.62 54.0 3.98e-01 100.0% 94.2%
3505438 604.1.1.67 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_5 0.62 54.0 5.29e-01 98.9% 91.0%
3232529 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.61 55.0 4.57e-01 100.0% 68.1%
3292830 109.52.1.1 alpha superhelices › Repetitive alpha hairpins › FRIGIDA flowering-time regulator › FRIGIDA flowering-time regulator › Frigida 0.61 54.0 3.92e-01 100.0% 38.9%
3996074 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 49.0 3.58e-01 93.5% 31.5%
3547013 621.1.1.8 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GVIN1 0.57 47.0 4.39e-01 91.3% 79.1%
3941216 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.56 49.0 4.56e-01 96.7% 83.5%
D4 medium residues 363-453
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.91 58.0 4.29e-01 72.5% 29.5%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 58.0 4.38e-01 98.9% 34.8%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 58.0 4.38e-01 83.5% 56.5%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 52.0 4.04e-01 93.4% 100.0%
2r40D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.56 40.0 2.93e-01 73.6% 94.4%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5083949 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.91 63.0 5.42e-01 98.9% 49.2%
3170491 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.85 65.0 4.77e-01 80.2% 40.0%
3965698 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.81 66.0 3.88e-01 84.6% 18.1%
3785883 4177.1.1.97 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147 0.79 59.0 4.56e-01 98.9% 38.4%
3207024 4177.1.1.9 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Snx8_BAR_dom 0.78 62.0 4.41e-01 83.5% 32.9%
4022048 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 51.0 4.03e-01 70.3% 34.9%
3755586 3291.1.1.118 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF9 0.75 66.0 5.52e-01 98.9% 59.3%
3607135 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 55.0 4.77e-01 76.9% 57.8%
3757451 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.73 62.0 5.00e-01 100.0% 50.6%
3608116 5086.1.1.177 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 0.72 61.0 5.12e-01 95.6% 55.9%
3220993 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.72 54.0 4.63e-01 79.1% 70.1%
3259629 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 54.0 5.23e-01 78.0% 100.0%
3599499 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 56.0 4.73e-01 98.9% 51.3%
3233827 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.68 48.0 4.35e-01 72.5% 79.2%
D5 medium residues 454-635
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00015.27 best MCPsignal 136.5 1.20e-39 89.6% 86.1%
D6 medium residues 636-686
PDB
Domain cluster: representative