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CAKLQF020000003.1__CAH1076444.1__SAMEA5780031_00786__00120
Bact-VirCAKLQF020000003.1__CAH1076444.1__SAMEA5780031_00786__00120
Identity
- Kingdom:
- phage
Quality
75.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-161
Domain cluster:
rep: CAKLQF020000003.1__CAH1076444.1__SAMEA5780031_00786__00120__D499-641
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01627.29 best | Hpt | 49.3 | 6.80e-13 | 63.5% | 84.5% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.91 | 69.0 | 7.82e-01 | 79.2% | 99.2% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.89 | 68.0 | 7.58e-01 | 78.6% | 99.2% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.73 | 55.0 | 5.25e-01 | 76.1% | 93.8% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.73 | 51.0 | 4.01e-01 | 71.7% | 93.6% |
| 3iqtA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.72 | 51.0 | 5.88e-01 | 75.5% | 100.0% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.72 | 54.0 | 5.13e-01 | 77.4% | 90.2% |
| 1c02A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.71 | 52.0 | 5.11e-01 | 74.8% | 97.6% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.70 | 50.0 | 5.43e-01 | 73.0% | 90.1% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.68 | 50.0 | 4.72e-01 | 75.5% | 91.1% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.67 | 47.0 | 4.77e-01 | 71.7% | 85.4% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.66 | 53.0 | 5.56e-01 | 88.1% | 92.5% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 38.0 | 3.89e-01 | 76.7% | 69.0% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 40.0 | 3.78e-01 | 85.5% | 62.9% |
| 2w53B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 36.0 | 3.58e-01 | 83.0% | 62.4% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.53 | 31.0 | 3.58e-01 | 74.2% | 78.6% |
| 3cskA02 | 3.30.540.30 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › | 0.52 | 42.0 | 4.20e-01 | 83.6% | 90.7% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.52 | 30.0 | 3.72e-01 | 76.7% | 89.2% |
| 6fdpA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 36.0 | 4.07e-01 | 84.3% | 93.3% |
| 3o60A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 32.0 | 3.11e-01 | 92.5% | 52.2% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.51 | 34.0 | 3.98e-01 | 86.8% | 97.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.51 | 37.0 | 3.38e-01 | 74.8% | 82.2% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 39.0 | 3.69e-01 | 82.4% | 66.1% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.50 | 33.0 | 3.74e-01 | 75.5% | 88.9% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3974600 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.93 | 72.0 | 8.05e-01 | 81.1% | 97.7% |
| 5007109 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 69.0 | 7.70e-01 | 78.0% | 93.8% |
| 4964703 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 69.0 | 7.60e-01 | 76.1% | 93.1% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.92 | 77.0 | 8.24e-01 | 86.2% | 100.0% |
| 3971675 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.91 | 71.0 | 7.92e-01 | 80.5% | 97.7% |
| 3386367 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.91 | 73.0 | 7.93e-01 | 81.8% | 98.5% |
| 54463 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.91 | 69.0 | 7.82e-01 | 79.2% | 99.2% |
| 5013248 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.91 | 66.0 | 7.44e-01 | 74.2% | 100.0% |
| 4464661 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 69.0 | 7.51e-01 | 78.6% | 91.9% |
| 184809 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 70.0 | 7.31e-01 | 79.2% | 87.6% |
| 4988730 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 66.0 | 7.51e-01 | 77.4% | 96.0% |
| 4927006 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 64.0 | 7.49e-01 | 74.8% | 100.0% |
| 4446522 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 69.0 | 7.35e-01 | 78.6% | 89.3% |
| 5041481 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.89 | 69.0 | 7.67e-01 | 79.2% | 97.7% |
| 138117 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.89 | 68.0 | 7.58e-01 | 78.6% | 99.2% |
| 5020418 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 67.0 | 7.19e-01 | 78.0% | 99.3% |
| 4949044 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 62.0 | 7.32e-01 | 74.2% | 100.0% |
| 4995268 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 66.0 | 7.32e-01 | 78.0% | 93.8% |
| 3974194 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.88 | 67.0 | 7.30e-01 | 78.6% | 93.3% |
| 3969575 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 67.0 | 7.31e-01 | 79.2% | 97.0% |
| 5051636 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 67.0 | 7.32e-01 | 79.2% | 97.8% |
| 4469856 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 65.0 | 7.33e-01 | 76.7% | 98.4% |
| 4502437 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 63.0 | 7.20e-01 | 76.7% | 100.0% |
| 3967074 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.85 | 62.0 | 7.17e-01 | 75.5% | 100.0% |
| 3971690 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.83 | 60.0 | 6.79e-01 | 77.4% | 94.4% |
| 3967073 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.79 | 58.0 | 6.61e-01 | 86.2% | 100.0% |
| 3970726 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.78 | 66.0 | 7.07e-01 | 87.4% | 100.0% |
| 3387197 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.78 | 61.0 | 6.66e-01 | 79.9% | 99.2% |
| 4340169 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.74 | 50.0 | 5.69e-01 | 70.4% | 89.4% |
| 3895523 | 601.1.2.75 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA | 0.73 | 54.0 | 4.90e-01 | 77.4% | 71.6% |
| 4567439 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.71 | 50.0 | 4.94e-01 | 72.3% | 95.3% |
| 3782324 | 5054.1.1.61 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO | 0.65 | 52.0 | 4.53e-01 | 83.6% | 83.7% |
| 3792275 | 5054.1.1.61 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO | 0.64 | 54.0 | 4.49e-01 | 89.3% | 75.2% |
| 4025954 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.59 | 43.0 | 3.74e-01 | 75.5% | 97.2% |
| 4948915 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 46.0 | 4.24e-01 | 84.9% | 89.5% |
| 5050796 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 32.0 | 3.98e-01 | 76.1% | 88.0% |
| 5039283 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 40.0 | 4.20e-01 | 84.3% | 80.0% |
| 4025201 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.56 | 30.0 | 3.52e-01 | 71.1% | 73.6% |
| 3411261 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 39.0 | 3.82e-01 | 86.2% | 67.2% |
| 3166299 | 109.4.1.520 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HemY_N | 0.51 | 38.0 | 3.28e-01 | 84.9% | 49.8% |
D2
high
residues 197-321
Domain cluster:
rep: CAKLQF020000003.1__CAH1076444.1__SAMEA5780031_00786__00120__D499-641
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01627.29 best | Hpt | 42.5 | 8.70e-11 | 92.0% | 85.7% |
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.90 | 70.0 | 7.67e-01 | 80.0% | 98.1% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.86 | 79.0 | 8.02e-01 | 100.0% | 98.4% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.86 | 81.0 | 8.06e-01 | 100.0% | 99.2% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.82 | 64.0 | 5.59e-01 | 81.6% | 72.8% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.81 | 58.0 | 5.77e-01 | 81.6% | 71.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.80 | 62.0 | 6.53e-01 | 80.8% | 96.5% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.79 | 58.0 | 6.45e-01 | 81.6% | 95.0% |
| 3pf0A00 | 1.20.1420.20 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif | 0.78 | 62.0 | 4.49e-01 | 82.4% | 46.5% |
| 2j9wB00 | 1.20.120.1130 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain | 0.78 | 59.0 | 6.54e-01 | 79.2% | 99.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.78 | 60.0 | 6.03e-01 | 81.6% | 96.9% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.77 | 60.0 | 5.34e-01 | 82.4% | 80.1% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.75 | 58.0 | 5.95e-01 | 80.8% | 97.5% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.75 | 57.0 | 5.39e-01 | 80.8% | 83.4% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.74 | 60.0 | 5.44e-01 | 85.6% | 80.1% |
| 3fajA00 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.74 | 55.0 | 6.02e-01 | 76.8% | 99.0% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.71 | 60.0 | 5.77e-01 | 89.6% | 94.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 54.0 | 5.30e-01 | 81.6% | 83.5% |
| 5tpmB00 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.69 | 60.0 | 5.81e-01 | 100.0% | 83.0% |
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.69 | 54.0 | 4.71e-01 | 83.2% | 99.5% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.68 | 53.0 | 4.60e-01 | 81.6% | 88.2% |
| 7akwA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 49.0 | 3.97e-01 | 99.2% | 41.9% |
| 2di3B02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.67 | 58.0 | 5.42e-01 | 100.0% | 75.5% |
| 6g94A00 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.67 | 52.0 | 4.65e-01 | 81.6% | 94.8% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.66 | 51.0 | 5.02e-01 | 80.8% | 91.7% |
| 4al0A00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.64 | 48.0 | 4.60e-01 | 79.2% | 91.8% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 33.0 | 3.51e-01 | 81.6% | 57.7% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 47.0 | 4.66e-01 | 78.4% | 100.0% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 40.0 | 3.96e-01 | 100.0% | 62.1% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 45.0 | 4.17e-01 | 78.4% | 67.7% |
| 1vljA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.57 | 43.0 | 3.62e-01 | 78.4% | 76.8% |
| 4k7cA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.57 | 45.0 | 3.08e-01 | 97.6% | 25.9% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 52.0 | 3.94e-01 | 100.0% | 84.0% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 39.0 | 3.46e-01 | 96.8% | 47.9% |
| 3ezuA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 42.0 | 3.76e-01 | 80.0% | 97.8% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 41.0 | 3.88e-01 | 80.0% | 94.1% |
| 2fonA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 40.0 | 3.95e-01 | 97.6% | 73.6% |
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 43.0 | 3.66e-01 | 100.0% | 51.2% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.53 | 45.0 | 4.17e-01 | 92.0% | 92.9% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.53 | 47.0 | 3.99e-01 | 96.8% | 64.5% |
| 2jbrA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 44.0 | 3.91e-01 | 100.0% | 62.7% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 39.0 | 3.24e-01 | 80.0% | 74.6% |
| 2np9A01 | 1.20.58.1300 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 40.0 | 3.90e-01 | 97.6% | 75.4% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.50 | 47.0 | 4.06e-01 | 100.0% | 84.4% |
ECOD (69)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4995268 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 84.0 | 8.33e-01 | 98.4% | 92.3% |
| 3971690 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 71.0 | 7.18e-01 | 81.6% | 84.0% |
| 3967556 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 64.0 | 7.18e-01 | 74.4% | 92.0% |
| 3974194 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.88 | 85.0 | 8.23e-01 | 100.0% | 92.6% |
| 3974600 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.87 | 82.0 | 8.13e-01 | 100.0% | 94.6% |
| 4988730 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 80.0 | 8.06e-01 | 98.4% | 96.0% |
| 3969575 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 83.0 | 8.07e-01 | 100.0% | 94.8% |
| 2392079 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.87 | 70.0 | 5.28e-01 | 82.4% | 40.3% |
| 5007109 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 80.0 | 7.94e-01 | 99.2% | 93.1% |
| 4446522 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 82.0 | 7.81e-01 | 100.0% | 87.9% |
| 4927006 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 76.0 | 7.92e-01 | 97.6% | 99.1% |
| 3971675 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.87 | 81.0 | 8.05e-01 | 100.0% | 94.6% |
| 4464661 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 81.0 | 7.91e-01 | 100.0% | 91.1% |
| 3386367 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 82.0 | 8.01e-01 | 100.0% | 94.8% |
| 184809 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 82.0 | 7.75e-01 | 100.0% | 86.9% |
| 54463 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.86 | 79.0 | 8.02e-01 | 100.0% | 98.4% |
| 4964703 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.86 | 79.0 | 7.82e-01 | 98.4% | 93.1% |
| 138117 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.86 | 81.0 | 8.06e-01 | 100.0% | 99.2% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.85 | 81.0 | 7.78e-01 | 100.0% | 91.4% |
| 5013248 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 81.0 | 8.15e-01 | 99.2% | 100.0% |
| 5020418 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 81.0 | 7.75e-01 | 100.0% | 99.3% |
| 4949044 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 74.0 | 7.78e-01 | 96.8% | 100.0% |
| 4469856 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 79.0 | 7.94e-01 | 100.0% | 98.4% |
| 3967074 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.85 | 77.0 | 7.93e-01 | 96.0% | 100.0% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.84 | 65.0 | 6.18e-01 | 80.8% | 90.3% |
| 3974601 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.84 | 66.0 | 7.02e-01 | 81.6% | 97.3% |
| 3823532 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.84 | 65.0 | 6.16e-01 | 80.8% | 90.3% |
| 3537779 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.83 | 65.0 | 5.93e-01 | 81.6% | 96.9% |
| 3970726 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.82 | 77.0 | 7.41e-01 | 100.0% | 90.0% |
| 143387 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.82 | 68.0 | 7.11e-01 | 86.4% | 96.5% |
| 4956385 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.81 | 63.0 | 5.61e-01 | 81.6% | 99.4% |
| 3387197 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.80 | 75.0 | 7.47e-01 | 100.0% | 96.2% |
| 3967073 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.80 | 71.0 | 7.29e-01 | 94.4% | 100.0% |
| 3631429 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 62.0 | 5.70e-01 | 81.6% | 85.6% |
| 4565794 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 62.0 | 6.00e-01 | 81.6% | 99.3% |
| 3239921 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.78 | 62.0 | 5.58e-01 | 82.4% | 81.2% |
| 3391109 | 3684.1.1.21 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 | 0.75 | 58.0 | 5.64e-01 | 81.6% | 99.3% |
| 3340986 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.75 | 58.0 | 4.96e-01 | 82.4% | 79.5% |
| 3430175 | 601.4.1.68 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Rx_N | 0.74 | 57.0 | 5.50e-01 | 81.6% | 93.0% |
| 3369650 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.74 | 58.0 | 5.41e-01 | 81.6% | 71.3% |
| 3587850 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.73 | 55.0 | 5.33e-01 | 78.4% | 100.0% |
| 3752923 | 601.4.1.42 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMEM138 | 0.73 | 57.0 | 5.27e-01 | 81.6% | 87.7% |
| 4954587 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.72 | 65.0 | 5.92e-01 | 98.4% | 84.2% |
| 3694451 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.70 | 51.0 | 4.03e-01 | 76.8% | 54.6% |
| 3444036 | 601.1.1.91 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1218 | 0.69 | 53.0 | 5.31e-01 | 80.0% | 100.0% |
| 4473547 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.69 | 55.0 | 4.96e-01 | 85.6% | 84.0% |
| 3594516 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 52.0 | 4.63e-01 | 84.8% | 96.2% |
| 3228799 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.61 | 47.0 | 4.11e-01 | 82.4% | 82.1% |
| 3675413 | 174.1.1.63 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PGG | 0.58 | 44.0 | 4.16e-01 | 95.2% | 66.9% |
| 5083762 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.58 | 46.0 | 3.65e-01 | 85.6% | 82.6% |
| 3438770 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.58 | 43.0 | 3.96e-01 | 78.4% | 80.6% |
| 4027540 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.56 | 43.0 | 3.98e-01 | 80.8% | 78.1% |
| 3653693 | 109.4.1.1375 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_SYVN1_N | 0.56 | 50.0 | 4.13e-01 | 100.0% | 72.2% |
| 4958350 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.55 | 42.0 | 3.59e-01 | 80.0% | 91.7% |
| 3761039 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.55 | 44.0 | 3.50e-01 | 84.8% | 77.1% |
| 3641904 | 109.4.1.1185 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BTB-POZ_ANK-like | 0.54 | 50.0 | 3.84e-01 | 100.0% | 71.1% |
| 3243709 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.53 | 42.0 | 3.45e-01 | 83.2% | 83.6% |
| 5041952 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 42.0 | 4.12e-01 | 84.0% | 96.3% |
| 3616727 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.53 | 43.0 | 3.55e-01 | 84.8% | 83.3% |
| 3616967 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.53 | 42.0 | 3.32e-01 | 84.8% | 73.3% |
| 3896580 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.53 | 42.0 | 3.45e-01 | 84.0% | 81.8% |
| 3561592 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.52 | 48.0 | 3.62e-01 | 100.0% | 65.2% |
| 4561477 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.52 | 47.0 | 3.60e-01 | 100.0% | 63.4% |
| 3232473 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.52 | 42.0 | 3.38e-01 | 84.8% | 77.9% |
| 3473984 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.52 | 42.0 | 3.34e-01 | 87.2% | 82.4% |
| 5051714 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.50 | 47.0 | 4.04e-01 | 100.0% | 97.9% |
| 3520822 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.50 | 46.0 | 3.80e-01 | 100.0% | 78.6% |
| 3927056 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.50 | 39.0 | 3.32e-01 | 83.2% | 85.2% |
| 3228858 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.50 | 41.0 | 3.48e-01 | 86.4% | 89.5% |
D3
high
residues 499-641
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01627.29 best | Hpt | 57.9 | 1.30e-15 | 71.3% | 91.7% |
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.94 | 67.0 | 7.91e-01 | 72.7% | 99.0% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.90 | 73.0 | 7.88e-01 | 85.3% | 96.8% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.88 | 72.0 | 7.57e-01 | 84.6% | 96.9% |
| 1sr2A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.85 | 56.0 | 6.25e-01 | 76.9% | 82.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.84 | 58.0 | 6.55e-01 | 70.6% | 100.0% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.82 | 59.0 | 5.34e-01 | 73.4% | 66.3% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.80 | 56.0 | 6.13e-01 | 72.0% | 97.5% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.78 | 52.0 | 6.14e-01 | 74.1% | 97.0% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 56.0 | 5.78e-01 | 74.8% | 91.8% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.76 | 55.0 | 4.98e-01 | 74.1% | 77.5% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.75 | 55.0 | 6.04e-01 | 76.2% | 98.3% |
| 1io1A01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.75 | 55.0 | 5.15e-01 | 74.8% | 76.3% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.74 | 54.0 | 5.04e-01 | 74.8% | 76.7% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.73 | 51.0 | 5.87e-01 | 71.3% | 100.0% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 51.0 | 5.57e-01 | 72.7% | 99.1% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.72 | 50.0 | 5.75e-01 | 72.0% | 100.0% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.72 | 56.0 | 5.83e-01 | 81.1% | 92.4% |
| 1c02A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.71 | 59.0 | 5.60e-01 | 86.7% | 95.8% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.71 | 55.0 | 5.81e-01 | 80.4% | 96.0% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 53.0 | 4.60e-01 | 77.6% | 57.9% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 37.0 | 4.61e-01 | 79.0% | 82.4% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 49.0 | 3.82e-01 | 75.5% | 81.9% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.67 | 48.0 | 5.19e-01 | 73.4% | 89.2% |
| 1nlxA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.65 | 44.0 | 5.03e-01 | 70.6% | 95.2% |
| 8h8jC01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.63 | 46.0 | 3.71e-01 | 74.8% | 82.7% |
| 3fp3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 36.0 | 3.74e-01 | 85.3% | 59.3% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.62 | 33.0 | 4.10e-01 | 73.4% | 82.2% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 53.0 | 4.25e-01 | 92.3% | 84.5% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.60 | 49.0 | 4.56e-01 | 85.3% | 94.8% |
| 3cskA02 | 3.30.540.30 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › | 0.59 | 45.0 | 4.33e-01 | 78.3% | 85.2% |
| 3kezA01 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 45.0 | 3.79e-01 | 80.4% | 79.6% |
| 4n1yB00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.57 | 42.0 | 3.59e-01 | 75.5% | 81.5% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 40.0 | 3.92e-01 | 81.1% | 65.2% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.56 | 37.0 | 3.98e-01 | 94.4% | 78.5% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.55 | 31.0 | 3.43e-01 | 86.0% | 68.2% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.55 | 35.0 | 4.10e-01 | 89.5% | 90.2% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.54 | 38.0 | 4.03e-01 | 84.6% | 79.1% |
| 2nwbA02 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 44.0 | 3.69e-01 | 85.3% | 94.9% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 44.0 | 3.39e-01 | 85.3% | 84.7% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 40.0 | 3.39e-01 | 76.2% | 83.8% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 44.0 | 3.59e-01 | 90.9% | 93.9% |
| 3rzeA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 45.0 | 3.64e-01 | 90.9% | 94.8% |
| 3tm8B00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.52 | 40.0 | 3.11e-01 | 79.0% | 72.0% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 38.0 | 3.46e-01 | 74.8% | 77.9% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 34.0 | 3.48e-01 | 74.8% | 67.6% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.51 | 39.0 | 4.04e-01 | 79.0% | 95.5% |
| 4ackB00 | 1.25.40.590 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU | 0.51 | 38.0 | 3.77e-01 | 78.3% | 85.6% |
ECOD (70)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3971675 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.96 | 80.0 | 8.42e-01 | 85.3% | 93.8% |
| 4964703 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.95 | 76.0 | 7.99e-01 | 81.8% | 90.8% |
| 3974600 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.95 | 79.0 | 8.35e-01 | 86.0% | 94.6% |
| 3386367 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.94 | 78.0 | 8.02e-01 | 84.6% | 92.6% |
| 5007109 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.93 | 76.0 | 8.00e-01 | 83.9% | 91.5% |
| 2392079 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.93 | 68.0 | 5.35e-01 | 74.8% | 41.1% |
| 4927006 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.93 | 72.0 | 8.06e-01 | 81.8% | 99.1% |
| 5051636 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.93 | 74.0 | 7.69e-01 | 82.5% | 91.9% |
| 4464661 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 77.0 | 7.94e-01 | 85.3% | 91.1% |
| 5013248 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 75.0 | 8.00e-01 | 83.2% | 99.2% |
| 5020418 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 76.0 | 7.68e-01 | 84.6% | 97.9% |
| 4446522 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 75.0 | 7.66e-01 | 84.6% | 87.1% |
| 4949044 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 70.0 | 7.89e-01 | 81.1% | 100.0% |
| 54463 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 73.0 | 7.88e-01 | 85.3% | 96.8% |
| 2833103 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 63.0 | 7.42e-01 | 72.0% | 99.0% |
| 4988730 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 71.0 | 7.67e-01 | 82.5% | 93.6% |
| 3970726 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 74.0 | 7.53e-01 | 85.3% | 87.9% |
| 3971690 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 72.0 | 7.70e-01 | 86.0% | 94.4% |
| 184809 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 74.0 | 7.40e-01 | 85.3% | 85.5% |
| 5041481 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.89 | 74.0 | 7.77e-01 | 85.3% | 95.4% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.89 | 79.0 | 8.06e-01 | 92.3% | 95.7% |
| 4469856 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 73.0 | 7.77e-01 | 84.6% | 98.4% |
| 3967074 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.88 | 71.0 | 7.79e-01 | 83.2% | 100.0% |
| 3969575 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 74.0 | 7.62e-01 | 86.7% | 96.3% |
| 3974601 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.88 | 64.0 | 7.30e-01 | 74.8% | 98.2% |
| 138117 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.88 | 72.0 | 7.57e-01 | 84.6% | 96.9% |
| 3974599 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.87 | 71.0 | 7.26e-01 | 84.6% | 89.3% |
| 4995268 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 69.0 | 7.25e-01 | 82.5% | 90.0% |
| 4502437 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.87 | 70.0 | 7.68e-01 | 84.6% | 100.0% |
| 143387 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.86 | 64.0 | 7.16e-01 | 76.2% | 95.6% |
| 3974194 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.86 | 70.0 | 7.23e-01 | 84.6% | 91.1% |
| 3967071 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.85 | 69.0 | 6.77e-01 | 83.9% | 82.0% |
| 4037098 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.85 | 61.0 | 6.98e-01 | 76.9% | 96.4% |
| 4947816 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.82 | 56.0 | 6.73e-01 | 72.7% | 100.0% |
| 3387197 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.81 | 69.0 | 7.20e-01 | 88.1% | 99.2% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 59.0 | 6.11e-01 | 75.5% | 87.4% |
| 3967073 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.79 | 62.0 | 6.78e-01 | 81.8% | 98.3% |
| 3220981 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.77 | 54.0 | 6.02e-01 | 71.3% | 99.1% |
| 3544880 | 601.39.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 › Serine_rich | 0.76 | 56.0 | 5.31e-01 | 75.5% | 94.5% |
| 4441047 | 601.4.1.50 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DUF6376 | 0.76 | 53.0 | 5.67e-01 | 72.0% | 97.6% |
| 3385577 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.75 | 53.0 | 5.52e-01 | 71.3% | 91.5% |
| 3382881 | 601.4.1.41 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Chloroplast_duf | 0.75 | 54.0 | 4.41e-01 | 74.8% | 78.8% |
| 3706847 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.74 | 55.0 | 4.42e-01 | 76.9% | 57.0% |
| 3967072 | 601.3.1.26 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF26379 | 0.74 | 67.0 | 6.28e-01 | 100.0% | 80.0% |
| 3354384 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.73 | 57.0 | 5.94e-01 | 81.1% | 88.1% |
| 4356766 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.69 | 50.0 | 4.68e-01 | 74.1% | 76.6% |
| 3248447 | 5054.1.1.9 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PKD_channel | 0.69 | 52.0 | 3.91e-01 | 77.6% | 51.0% |
| 3586819 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.69 | 49.0 | 4.60e-01 | 72.0% | 65.9% |
| 4588340 | 6155.2.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › PnuC › PnuC › LAB_N | 0.68 | 49.0 | 4.31e-01 | 74.8% | 88.8% |
| 3600745 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.68 | 55.0 | 3.43e-01 | 86.0% | 62.2% |
| 3933688 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.68 | 48.0 | 3.65e-01 | 73.4% | 81.4% |
| 3939708 | 601.24.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0.67 | 47.0 | 5.32e-01 | 72.0% | 98.2% |
| 3233741 | 5001.1.1.69 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd | 0.67 | 47.0 | 3.67e-01 | 72.0% | 82.2% |
| 3444721 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.66 | 37.0 | 3.28e-01 | 76.9% | 40.5% |
| 3559003 | 192.2.1.1 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 | 0.64 | 32.0 | 3.80e-01 | 74.1% | 68.0% |
| 3302202 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.63 | 54.0 | 4.12e-01 | 93.0% | 70.0% |
| 5018766 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 47.0 | 3.77e-01 | 82.5% | 43.6% |
| 4501248 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 43.0 | 4.06e-01 | 74.1% | 95.9% |
| 5063459 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.58 | 43.0 | 4.04e-01 | 78.3% | 71.1% |
| 4576287 | 3755.3.1.471 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin | 0.57 | 33.0 | 3.24e-01 | 74.1% | 52.9% |
| 3782809 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.55 | 41.0 | 3.77e-01 | 76.9% | 87.2% |
| 3263853 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 41.0 | 3.64e-01 | 76.9% | 88.7% |
| 4309655 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 43.0 | 3.66e-01 | 84.6% | 87.8% |
| 3187296 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 40.0 | 3.45e-01 | 76.2% | 84.7% |
| 3616727 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 40.0 | 3.49e-01 | 76.9% | 81.9% |
| 4034479 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.53 | 44.0 | 3.94e-01 | 87.4% | 68.5% |
| 5013396 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.53 | 46.0 | 4.10e-01 | 95.1% | 90.0% |
| 4424383 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.52 | 34.0 | 3.20e-01 | 74.1% | 54.9% |
| 3909416 | 5001.1.1.11 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_4 | 0.52 | 44.0 | 3.52e-01 | 95.1% | 85.2% |
| 3601214 | 5048.1.1.0 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like | 0.51 | 41.0 | 3.49e-01 | 84.6% | 91.5% |
D4
high
residues 727-840
Domain cluster:
rep: CAKLQF020000003.1__CAH1076444.1__SAMEA5780031_00786__00120__D499-641
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01627.29 best | Hpt | 51.6 | 1.30e-13 | 82.5% | 67.9% |
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.93 | 79.0 | 8.27e-01 | 87.7% | 96.2% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.91 | 87.0 | 8.45e-01 | 100.0% | 94.4% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.90 | 65.0 | 6.95e-01 | 88.6% | 84.0% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.90 | 85.0 | 8.15e-01 | 100.0% | 95.3% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.89 | 73.0 | 7.43e-01 | 86.0% | 100.0% |
| 1sr2A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.86 | 63.0 | 6.31e-01 | 88.6% | 74.1% |
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.84 | 70.0 | 5.00e-01 | 86.8% | 48.3% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.83 | 69.0 | 5.78e-01 | 87.7% | 64.1% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 57.0 | 5.09e-01 | 71.1% | 96.1% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.81 | 66.0 | 6.53e-01 | 86.0% | 94.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.81 | 68.0 | 6.39e-01 | 88.6% | 97.0% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.80 | 64.0 | 5.57e-01 | 84.2% | 81.3% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.79 | 66.0 | 6.24e-01 | 88.6% | 82.7% |
| 1c02A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.79 | 67.0 | 5.77e-01 | 88.6% | 77.7% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.78 | 65.0 | 6.32e-01 | 87.7% | 88.8% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.77 | 64.0 | 5.37e-01 | 87.7% | 74.9% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.77 | 60.0 | 5.67e-01 | 81.6% | 83.5% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.76 | 58.0 | 5.55e-01 | 79.8% | 100.0% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.75 | 58.0 | 5.82e-01 | 82.5% | 83.9% |
| 5x56B00 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.75 | 60.0 | 6.25e-01 | 86.0% | 100.0% |
| 1s3qG00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 55.0 | 4.86e-01 | 77.2% | 96.3% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.74 | 60.0 | 5.75e-01 | 86.0% | 82.4% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 60.0 | 4.94e-01 | 88.6% | 64.6% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.73 | 59.0 | 6.21e-01 | 86.0% | 100.0% |
| 2cdqA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.72 | 52.0 | 5.55e-01 | 74.6% | 94.8% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.70 | 59.0 | 5.16e-01 | 90.4% | 97.0% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.69 | 50.0 | 4.07e-01 | 75.4% | 91.6% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 56.0 | 4.11e-01 | 88.6% | 79.6% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 52.0 | 5.11e-01 | 94.7% | 75.6% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.67 | 45.0 | 4.69e-01 | 70.2% | 74.5% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.66 | 51.0 | 4.60e-01 | 80.7% | 77.1% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.64 | 56.0 | 5.09e-01 | 100.0% | 70.9% |
| 3bhqA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.64 | 45.0 | 3.71e-01 | 71.9% | 74.8% |
| 3rmgA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.62 | 51.0 | 3.78e-01 | 88.6% | 41.8% |
| 2hs5A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.62 | 54.0 | 5.09e-01 | 100.0% | 77.9% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 53.0 | 4.43e-01 | 92.1% | 55.3% |
| 1ciyA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.61 | 56.0 | 4.45e-01 | 100.0% | 73.3% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.60 | 54.0 | 4.71e-01 | 100.0% | 94.2% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 49.0 | 4.17e-01 | 95.6% | 90.6% |
| 2nwbA02 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 53.0 | 4.08e-01 | 100.0% | 94.9% |
| 7qx4A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.57 | 51.0 | 4.05e-01 | 100.0% | 65.8% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 40.0 | 3.84e-01 | 71.9% | 97.7% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 3.78e-01 | 89.5% | 83.3% |
| 6gpxB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 50.0 | 3.84e-01 | 100.0% | 68.8% |
| 4im7A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.54 | 43.0 | 3.58e-01 | 86.0% | 98.1% |
| 4hkaA01 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 49.0 | 3.61e-01 | 100.0% | 84.4% |
| 3tp3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 40.0 | 3.75e-01 | 84.2% | 81.8% |
| 1euhA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.51 | 44.0 | 3.46e-01 | 99.1% | 94.5% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 45.0 | 3.76e-01 | 100.0% | 58.1% |
| 2wapA00 | 3.90.1300.10 | Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain | 0.50 | 44.0 | 2.90e-01 | 100.0% | 46.2% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3971675 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.95 | 92.0 | 8.73e-01 | 100.0% | 91.5% |
| 3386367 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.95 | 92.0 | 8.56e-01 | 100.0% | 91.1% |
| 5041481 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.95 | 92.0 | 8.69e-01 | 100.0% | 93.1% |
| 4464661 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.95 | 91.0 | 8.52e-01 | 100.0% | 88.9% |
| 4988730 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.94 | 89.0 | 8.57e-01 | 97.4% | 92.0% |
| 4927006 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.94 | 90.0 | 8.97e-01 | 98.2% | 99.1% |
| 3974600 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.94 | 91.0 | 8.63e-01 | 100.0% | 91.5% |
| 4964703 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.94 | 87.0 | 8.29e-01 | 96.5% | 89.2% |
| 5020418 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.94 | 90.0 | 8.28e-01 | 100.0% | 96.4% |
| 4446522 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.93 | 90.0 | 8.23e-01 | 100.0% | 85.7% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.93 | 89.0 | 8.21e-01 | 100.0% | 86.4% |
| 4949044 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.93 | 88.0 | 8.91e-01 | 98.2% | 100.0% |
| 3969575 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 88.0 | 8.24e-01 | 100.0% | 93.3% |
| 184809 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 88.0 | 7.97e-01 | 100.0% | 83.4% |
| 5051636 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.92 | 86.0 | 7.99e-01 | 97.4% | 90.4% |
| 2392079 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.92 | 79.0 | 5.76e-01 | 88.6% | 38.8% |
| 3971690 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.91 | 78.0 | 7.54e-01 | 88.6% | 81.6% |
| 4469856 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.91 | 87.0 | 8.38e-01 | 100.0% | 96.8% |
| 4037098 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.91 | 74.0 | 7.61e-01 | 87.7% | 88.2% |
| 3974599 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 85.0 | 7.87e-01 | 100.0% | 90.7% |
| 2833103 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.90 | 76.0 | 8.01e-01 | 88.6% | 97.1% |
| 138117 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.90 | 85.0 | 8.15e-01 | 100.0% | 95.3% |
| 4502437 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.89 | 85.0 | 8.36e-01 | 100.0% | 98.3% |
| 3974601 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.89 | 75.0 | 7.68e-01 | 87.7% | 93.6% |
| 3970726 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.89 | 85.0 | 7.81e-01 | 100.0% | 86.4% |
| 4995268 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.89 | 83.0 | 7.90e-01 | 98.2% | 90.0% |
| 3967074 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.89 | 84.0 | 8.26e-01 | 99.1% | 99.2% |
| 3967071 | 601.3.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27543 | 0.88 | 83.0 | 7.46e-01 | 100.0% | 82.0% |
| 143387 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.86 | 76.0 | 7.73e-01 | 92.1% | 94.7% |
| 3790952 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.85 | 71.0 | 6.50e-01 | 88.6% | 92.4% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.84 | 70.0 | 6.36e-01 | 86.8% | 87.6% |
| 3236489 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.84 | 70.0 | 6.57e-01 | 87.7% | 81.5% |
| 3967556 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.83 | 64.0 | 6.85e-01 | 83.3% | 92.0% |
| 3740639 | 601.3.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt | 0.83 | 68.0 | 6.16e-01 | 88.6% | 66.9% |
| 3382881 | 601.4.1.41 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Chloroplast_duf | 0.81 | 68.0 | 5.11e-01 | 88.6% | 74.2% |
| 3967073 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.81 | 75.0 | 7.35e-01 | 98.2% | 99.2% |
| 3586819 | 601.11.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain | 0.79 | 61.0 | 5.32e-01 | 81.6% | 65.3% |
| 5079776 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.78 | 63.0 | 5.20e-01 | 84.2% | 65.8% |
| 4441047 | 601.4.1.50 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DUF6376 | 0.78 | 64.0 | 6.24e-01 | 87.7% | 96.0% |
| 3217635 | 3684.1.1.30 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 | 0.78 | 64.0 | 5.60e-01 | 88.6% | 79.4% |
| 3241745 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.77 | 64.0 | 5.73e-01 | 88.6% | 78.7% |
| 3466116 | 192.29.1.25 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like | 0.77 | 62.0 | 6.15e-01 | 86.0% | 96.7% |
| 4928415 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.75 | 52.0 | 3.96e-01 | 71.9% | 50.6% |
| 4588340 | 6155.2.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › PnuC › PnuC › LAB_N | 0.73 | 60.0 | 4.82e-01 | 86.8% | 89.8% |
| 5063260 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.73 | 60.0 | 6.18e-01 | 87.7% | 95.5% |
| 3603137 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 59.0 | 5.09e-01 | 100.0% | 60.0% |
| 3575213 | 109.4.1.649 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4807 | 0.70 | 61.0 | 5.63e-01 | 100.0% | 74.3% |
| 5013396 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.70 | 56.0 | 4.62e-01 | 85.1% | 83.0% |
| 4963550 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.68 | 57.0 | 4.74e-01 | 91.2% | 95.5% |
| 3899017 | 3543.1.1.0 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel | 0.66 | 59.0 | 4.97e-01 | 98.2% | 74.7% |
| 4956963 | 180.1.1.0 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase | 0.66 | 58.0 | 5.02e-01 | 96.5% | 84.6% |
| 3816396 | 3543.1.1.4 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF716 | 0.65 | 58.0 | 4.56e-01 | 96.5% | 73.2% |
| 4984604 | 180.1.1.0 ↗ | alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase | 0.64 | 58.0 | 4.87e-01 | 99.1% | 78.9% |
| 3257393 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 59.0 | 4.89e-01 | 100.0% | 71.1% |
| 3701155 | 109.4.1.235 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 | 0.62 | 57.0 | 4.51e-01 | 100.0% | 86.2% |
| 3901045 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 53.0 | 4.78e-01 | 89.5% | 73.1% |
| 4008904 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.60 | 37.0 | 2.63e-01 | 88.6% | 21.9% |
| 3468690 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 4.69e-01 | 95.6% | 77.6% |
| 3756948 | 601.19.1.17 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Niban2 | 0.59 | 48.0 | 4.24e-01 | 89.5% | 79.4% |
| 3263853 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.56 | 48.0 | 3.93e-01 | 88.6% | 87.7% |
| 3616727 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.54 | 48.0 | 3.96e-01 | 98.2% | 93.8% |
| 3892831 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 47.0 | 3.83e-01 | 96.5% | 61.4% |
| 4998236 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.53 | 43.0 | 2.88e-01 | 86.8% | 61.5% |
| 4988301 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.52 | 44.0 | 3.93e-01 | 86.8% | 83.3% |
| 4177363 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 43.0 | 3.96e-01 | 87.7% | 77.2% |
| 3472795 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 43.0 | 4.10e-01 | 89.5% | 87.7% |
D5
high
residues 1218-1371
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01584.25 best | CheW | 82.1 | 4.30e-23 | 90.3% | 97.8% |
CATH (2)
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5016330 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.94 | 35.0 | 6.08e-01 | 88.3% | 96.7% |
| 3970756 | 2.10.1.0 ↗ | beta barrels › OB-fold › CheW › CheW | 0.90 | 83.0 | 8.10e-01 | 94.8% | 91.5% |
| 5020421 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.90 | 73.0 | 8.00e-01 | 88.3% | 99.2% |
| 4385582 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.90 | 76.0 | 8.12e-01 | 92.9% | 99.3% |
| 3838306 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.90 | 78.0 | 8.09e-01 | 95.5% | 95.9% |
| 1178512 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.89 | 73.0 | 7.89e-01 | 90.3% | 98.5% |
| 4377808 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.89 | 72.0 | 7.79e-01 | 88.3% | 97.0% |
| 4302514 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.89 | 72.0 | 7.87e-01 | 88.3% | 99.2% |
| 5007113 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.89 | 72.0 | 7.81e-01 | 89.6% | 98.5% |
| 5041484 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.89 | 75.0 | 8.06e-01 | 90.3% | 100.0% |
| 4949046 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.88 | 77.0 | 8.09e-01 | 92.2% | 99.3% |
| 4949981 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.88 | 69.0 | 7.70e-01 | 89.0% | 100.0% |
| 3969587 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.87 | 78.0 | 8.02e-01 | 95.5% | 97.9% |
| 4482101 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.87 | 74.0 | 7.91e-01 | 92.2% | 100.0% |
| 4988734 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.87 | 65.0 | 7.42e-01 | 87.7% | 100.0% |
| 4930200 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.87 | 71.0 | 7.69e-01 | 92.9% | 99.2% |
| 5051640 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.86 | 75.0 | 7.79e-01 | 93.5% | 95.9% |
| 4479028 | 2.10.1.0 ↗ | beta barrels › OB-fold › CheW › CheW | 0.86 | 60.0 | 7.09e-01 | 91.6% | 100.0% |
| 4964707 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.85 | 70.0 | 7.47e-01 | 94.2% | 96.3% |
| 3968991 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.84 | 74.0 | 7.69e-01 | 96.1% | 97.2% |
| 4927009 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.83 | 70.0 | 7.34e-01 | 87.0% | 99.3% |
| 5038808 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.81 | 69.0 | 7.34e-01 | 92.9% | 100.0% |
| 3387448 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.81 | 70.0 | 7.22e-01 | 89.6% | 98.6% |
| 4995271 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.80 | 56.0 | 6.59e-01 | 79.9% | 100.0% |
| 4950861 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.80 | 71.0 | 7.13e-01 | 92.9% | 98.1% |
| 4662872 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.80 | 68.0 | 7.22e-01 | 90.3% | 100.0% |
| 4661427 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.80 | 70.0 | 7.29e-01 | 92.2% | 97.9% |
| 4931741 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.79 | 70.0 | 7.14e-01 | 92.2% | 99.3% |
| 4964711 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.79 | 66.0 | 7.06e-01 | 88.3% | 98.5% |
| 4994835 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.79 | 66.0 | 7.11e-01 | 90.9% | 100.0% |
| 5050253 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.79 | 71.0 | 7.20e-01 | 93.5% | 98.0% |
| 4145388 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.79 | 68.0 | 7.19e-01 | 92.2% | 99.3% |
| 3839271 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.78 | 69.0 | 6.98e-01 | 92.9% | 98.1% |
| 5016331 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 67.0 | 7.08e-01 | 90.9% | 100.0% |
| 3967460 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 69.0 | 7.08e-01 | 94.2% | 98.7% |
| 4319178 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 67.0 | 7.01e-01 | 92.9% | 100.0% |
| 4988726 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 67.0 | 6.86e-01 | 93.5% | 94.0% |
| 3971152 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 68.0 | 7.05e-01 | 92.9% | 98.6% |
| 3967325 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.77 | 70.0 | 7.11e-01 | 97.4% | 98.0% |
| 4949051 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.76 | 63.0 | 6.82e-01 | 89.0% | 100.0% |
| 4204475 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.76 | 67.0 | 6.85e-01 | 92.9% | 96.7% |
| 4240075 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.75 | 65.0 | 6.77e-01 | 90.3% | 99.3% |
| 4681343 | 2.10.1.0 ↗ | beta barrels › OB-fold › CheW › CheW | 0.75 | 46.0 | 5.73e-01 | 90.9% | 98.9% |
| 3967712 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.73 | 64.0 | 6.62e-01 | 90.9% | 100.0% |
| 164917 | 2.10.1.1 ↗ | beta barrels › OB-fold › CheW › CheW › CheW | 0.72 | 64.0 | 6.28e-01 | 94.2% | 88.0% |
| 3616998 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.51 | 29.0 | 3.46e-01 | 72.1% | 86.3% |
D6
high
residues 1372-1505
Domain cluster:
rep: DGJ7_scaffold_2_2069_prodigal-single.1__X__X__00303__D2-112
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00072.31 best | Response_reg | 107.1 | 8.00e-31 | 84.3% | 99.1% |
D7
medium
residues 911-957_995-1032
Domain cluster:
representative
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5ha6B00 | 1.10.287.210 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.90 | 69.0 | 7.13e-01 | 80.0% | 100.0% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.88 | 73.0 | 6.75e-01 | 87.1% | 100.0% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.86 | 78.0 | 7.75e-01 | 96.5% | 93.2% |
| 1yf2A02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.81 | 60.0 | 5.52e-01 | 77.6% | 98.1% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.79 | 72.0 | 6.08e-01 | 100.0% | 83.5% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.76 | 70.0 | 4.46e-01 | 100.0% | 25.6% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 70.0 | 6.41e-01 | 100.0% | 89.0% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 55.0 | 5.72e-01 | 91.8% | 84.4% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.73 | 63.0 | 6.40e-01 | 92.9% | 98.8% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 52.0 | 5.35e-01 | 74.1% | 81.5% |
| 4i0xG00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 55.0 | 6.06e-01 | 82.4% | 100.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 56.0 | 6.09e-01 | 89.4% | 100.0% |
| 1fxkC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 63.0 | 5.42e-01 | 100.0% | 91.0% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 52.0 | 5.26e-01 | 88.2% | 80.2% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.68 | 49.0 | 5.49e-01 | 83.5% | 100.0% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.68 | 58.0 | 5.74e-01 | 95.3% | 88.8% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.66 | 59.0 | 4.03e-01 | 100.0% | 99.0% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 49.0 | 5.21e-01 | 87.1% | 98.6% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 41.0 | 4.15e-01 | 75.3% | 66.3% |
| 4jioA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.62 | 55.0 | 4.61e-01 | 97.6% | 66.4% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.59 | 47.0 | 4.91e-01 | 88.2% | 96.2% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 46.0 | 4.00e-01 | 87.1% | 69.2% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4937739 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 72.0 | 6.09e-01 | 95.3% | 80.0% |
| 3678035 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.79 | 61.0 | 6.73e-01 | 80.0% | 97.1% |
| 5041482 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.79 | 70.0 | 6.71e-01 | 94.1% | 87.4% |
| 4304756 | 605.2.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N | 0.77 | 67.0 | 6.04e-01 | 91.8% | 70.9% |
| 4349607 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.76 | 63.0 | 5.72e-01 | 88.2% | 73.6% |
| 4429833 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.74 | 63.0 | 5.78e-01 | 91.8% | 70.9% |
| 4057547 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.73 | 63.0 | 5.73e-01 | 91.8% | 70.9% |
| 3229095 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.73 | 62.0 | 5.89e-01 | 92.9% | 96.0% |
| 4497098 | 3291.1.1.195 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › H-kinase_dim | 0.73 | 62.0 | 5.55e-01 | 94.1% | 93.3% |
| 4033238 | 101.1.2.804 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF27113 | 0.72 | 60.0 | 4.66e-01 | 88.2% | 56.0% |
| 3999727 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.71 | 63.0 | 4.07e-01 | 100.0% | 87.0% |
| 3729994 | 3755.3.1.284 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Utp11 | 0.71 | 55.0 | 4.77e-01 | 83.5% | 56.9% |
| 3415405 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.70 | 62.0 | 3.92e-01 | 98.8% | 82.0% |
| 3740547 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.70 | 62.0 | 5.64e-01 | 96.5% | 73.6% |
| 3592587 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.70 | 62.0 | 5.49e-01 | 100.0% | 74.4% |
| 3496957 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.69 | 62.0 | 3.73e-01 | 100.0% | 45.9% |
| 3941960 | 5086.1.1.86 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG | 0.67 | 56.0 | 4.93e-01 | 97.6% | 62.4% |
D8
medium
residues 1033-1166_1180-1198
Domain cluster:
rep: Ig7659_scaffold_8_prodigal-single.1__X__X__00240__D301-446
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02518.32 best | HATPase_c | 33.4 | 7.70e-08 | 73.9% | 80.2% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1b3qB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.96 | 94.0 | 8.65e-01 | 100.0% | 90.8% |
| 4gt8A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.86 | 60.0 | 6.46e-01 | 100.0% | 82.0% |
| 4r3aA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.86 | 65.0 | 6.77e-01 | 100.0% | 83.8% |
| 6lgqC01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.85 | 62.0 | 6.74e-01 | 100.0% | 87.8% |
| 1gkxA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.83 | 68.0 | 6.84e-01 | 100.0% | 85.4% |
| 3ehgA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.83 | 58.0 | 6.39e-01 | 99.3% | 87.2% |
| 4q20A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.82 | 65.0 | 6.65e-01 | 100.0% | 84.6% |
| 1id0A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.81 | 64.0 | 6.57e-01 | 100.0% | 85.6% |
| 4pl9A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.80 | 62.0 | 6.31e-01 | 100.0% | 81.3% |
| 3zxoA00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.80 | 55.0 | 6.03e-01 | 100.0% | 84.8% |
| 4bixB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.80 | 62.0 | 6.30e-01 | 100.0% | 82.4% |
| 3d36B01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.79 | 63.0 | 6.21e-01 | 100.0% | 78.1% |
| 7zp0A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.79 | 65.0 | 6.70e-01 | 100.0% | 89.0% |
| 7n0eB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.79 | 54.0 | 6.00e-01 | 100.0% | 86.9% |
| 6rh8A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.79 | 67.0 | 6.68e-01 | 100.0% | 86.1% |
| 1y8oA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.78 | 69.0 | 6.62e-01 | 100.0% | 82.4% |
| 4gczB03 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.78 | 63.0 | 6.24e-01 | 100.0% | 80.1% |
| 4kp4A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.76 | 59.0 | 6.05e-01 | 100.0% | 83.8% |
| 4fppA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.75 | 57.0 | 5.98e-01 | 100.0% | 86.9% |
| 4qpkB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.72 | 54.0 | 5.79e-01 | 100.0% | 88.8% |
| 1y4uB01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.67 | 41.0 | 3.82e-01 | 75.2% | 47.4% |
| 4hlbA00 | 3.30.70.2960 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 28.0 | 3.36e-01 | 97.4% | 77.9% |
| 1httA01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.51 | 38.0 | 3.17e-01 | 76.5% | 95.1% |
ECOD (65)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3970750 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.99 | 97.0 | 8.95e-01 | 100.0% | 89.7% |
| 4221328 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.98 | 96.0 | 8.52e-01 | 100.0% | 84.0% |
| 4949045 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.97 | 74.0 | 7.81e-01 | 100.0% | 85.0% |
| 4995270 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.97 | 95.0 | 8.73e-01 | 100.0% | 90.8% |
| 3969589 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.96 | 93.0 | 8.58e-01 | 100.0% | 90.8% |
| 5051639 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.94 | 91.0 | 8.17e-01 | 100.0% | 84.0% |
| 2756400 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.88 | 64.0 | 6.86e-01 | 100.0% | 83.8% |
| 4010324 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.85 | 60.0 | 6.26e-01 | 100.0% | 77.6% |
| 3965082 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.84 | 61.0 | 6.62e-01 | 100.0% | 86.9% |
| 3968308 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.84 | 60.0 | 6.39e-01 | 100.0% | 83.0% |
| 5045473 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.83 | 63.0 | 6.43e-01 | 100.0% | 79.3% |
| 4545540 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.83 | 59.0 | 5.15e-01 | 100.0% | 51.2% |
| 4968257 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.83 | 67.0 | 6.97e-01 | 100.0% | 90.7% |
| 3978888 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.83 | 65.0 | 6.47e-01 | 100.0% | 78.5% |
| 5046356 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.83 | 63.0 | 6.32e-01 | 100.0% | 77.4% |
| 4376160 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.82 | 65.0 | 6.34e-01 | 100.0% | 75.8% |
| 5044552 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.82 | 62.0 | 6.31e-01 | 100.0% | 79.3% |
| 3987968 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.82 | 55.0 | 6.01e-01 | 97.4% | 80.8% |
| 4987529 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.82 | 65.0 | 6.57e-01 | 100.0% | 81.8% |
| 4065430 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 65.0 | 6.55e-01 | 100.0% | 82.4% |
| 4984596 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 66.0 | 6.54e-01 | 100.0% | 80.6% |
| 5040731 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 65.0 | 6.61e-01 | 100.0% | 84.7% |
| 6565 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 57.0 | 6.39e-01 | 88.9% | 90.9% |
| 4944569 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.81 | 64.0 | 6.49e-01 | 100.0% | 83.3% |
| 3967309 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 64.0 | 6.53e-01 | 100.0% | 83.3% |
| 5040662 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 64.0 | 6.46e-01 | 100.0% | 81.3% |
| 4965150 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.81 | 63.0 | 6.35e-01 | 100.0% | 80.0% |
| 5035201 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 66.0 | 6.63e-01 | 100.0% | 83.9% |
| 3978906 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 65.0 | 5.80e-01 | 100.0% | 62.4% |
| 3971474 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 57.0 | 6.00e-01 | 98.0% | 80.0% |
| 3289537 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 57.0 | 6.05e-01 | 100.0% | 83.5% |
| 4125095 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 63.0 | 6.35e-01 | 100.0% | 81.3% |
| 5018915 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 68.0 | 6.70e-01 | 100.0% | 84.4% |
| 3283806 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.79 | 57.0 | 5.94e-01 | 100.0% | 80.0% |
| 4629118 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 55.0 | 5.84e-01 | 98.0% | 80.0% |
| 4184227 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 64.0 | 6.38e-01 | 100.0% | 81.6% |
| 4543685 | 225.1.1.17 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c+His_kinase | 0.79 | 64.0 | 5.75e-01 | 100.0% | 63.5% |
| 4980671 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.79 | 61.0 | 6.78e-01 | 96.7% | 98.4% |
| 4939265 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 63.0 | 6.63e-01 | 100.0% | 90.7% |
| 4355768 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 66.0 | 6.60e-01 | 100.0% | 85.8% |
| 5061317 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.79 | 65.0 | 6.93e-01 | 100.0% | 97.0% |
| 3943157 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.78 | 65.0 | 6.48e-01 | 100.0% | 84.5% |
| 3974814 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.78 | 55.0 | 5.81e-01 | 98.0% | 80.7% |
| 3969529 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.77 | 60.0 | 6.14e-01 | 100.0% | 82.7% |
| 3973209 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.77 | 69.0 | 6.56e-01 | 100.0% | 81.7% |
| 3281361 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.77 | 56.0 | 5.87e-01 | 100.0% | 81.4% |
| 3943630 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.77 | 63.0 | 6.22e-01 | 100.0% | 81.2% |
| 5001955 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.77 | 64.0 | 6.37e-01 | 100.0% | 85.2% |
| 3588295 | 225.1.1.17 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c+His_kinase | 0.76 | 63.0 | 5.58e-01 | 100.0% | 62.3% |
| 3288053 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.76 | 56.0 | 5.75e-01 | 100.0% | 80.0% |
| 3282900 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.75 | 61.0 | 6.15e-01 | 100.0% | 83.9% |
| 3291208 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.74 | 60.0 | 5.92e-01 | 100.0% | 80.0% |
| 4962399 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.73 | 63.0 | 6.03e-01 | 100.0% | 80.0% |
| 5056109 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.73 | 69.0 | 6.47e-01 | 100.0% | 84.4% |
| 4420511 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.73 | 53.0 | 5.88e-01 | 86.9% | 94.2% |
| 3974252 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.73 | 62.0 | 6.03e-01 | 100.0% | 82.4% |
| 3988297 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.72 | 62.0 | 6.17e-01 | 100.0% | 86.9% |
| 3688529 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.71 | 67.0 | 6.34e-01 | 100.0% | 87.2% |
| 3280200 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.69 | 58.0 | 5.79e-01 | 100.0% | 85.6% |
| 3659117 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.66 | 35.0 | 3.39e-01 | 70.6% | 44.6% |
| 3820422 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.63 | 57.0 | 5.49e-01 | 100.0% | 85.9% |
| 3365830 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.60 | 55.0 | 5.18e-01 | 100.0% | 81.1% |
| 3671286 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.58 | 53.0 | 5.04e-01 | 100.0% | 83.3% |
| 5050683 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.56 | 32.0 | 3.51e-01 | 96.7% | 67.2% |
| 3038102 | 1.1.3.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › AbrB | 0.51 | 17.0 | 2.62e-01 | 74.5% | 71.4% |