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CAKLQF020000003.1__CAH1076474.1__SAMEA5780031_00802__00130
Bact-VirCAKLQF020000003.1__CAH1076474.1__SAMEA5780031_00802__00130
Identity
- Kingdom:
- phage
Quality
85.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 134-328
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12805.14 best | FUSC-like | 167.5 | 4.80e-49 | 94.4% | 65.5% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3kmiA00 | 1.20.120.940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain | 0.85 | 72.0 | 7.65e-01 | 97.4% | 98.8% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.80 | 75.0 | 7.38e-01 | 99.5% | 99.5% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.79 | 73.0 | 7.30e-01 | 98.5% | 99.0% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 45.0 | 4.55e-01 | 85.1% | 63.7% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.71 | 41.0 | 5.35e-01 | 90.3% | 100.0% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.68 | 40.0 | 4.98e-01 | 94.9% | 94.0% |
| 8ipqB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.63 | 44.0 | 3.81e-01 | 70.3% | 75.5% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 34.0 | 4.44e-01 | 100.0% | 92.0% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 51.0 | 5.17e-01 | 83.6% | 96.4% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 53.0 | 5.06e-01 | 99.0% | 83.4% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 45.0 | 4.33e-01 | 84.6% | 72.3% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 38.0 | 4.41e-01 | 88.2% | 94.9% |
| 2pybA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 39.0 | 4.34e-01 | 86.2% | 91.4% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 44.0 | 4.26e-01 | 85.1% | 74.0% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 36.0 | 4.19e-01 | 87.2% | 92.6% |
| 3ce2A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.54 | 38.0 | 4.21e-01 | 89.2% | 88.3% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 36.0 | 4.24e-01 | 72.8% | 100.0% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 37.0 | 4.18e-01 | 87.2% | 95.1% |
| 5d91A02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.52 | 40.0 | 4.06e-01 | 85.1% | 78.8% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 38.0 | 4.18e-01 | 88.2% | 93.6% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 39.0 | 4.24e-01 | 79.5% | 94.9% |
| 7sgrA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 37.0 | 3.10e-01 | 74.4% | 45.8% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 44.0 | 3.66e-01 | 90.8% | 92.1% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 41.0 | 4.39e-01 | 86.2% | 95.9% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.51 | 38.0 | 3.71e-01 | 85.6% | 68.8% |
| 3ddeB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.51 | 38.0 | 3.65e-01 | 85.6% | 64.5% |
| 7zo9A01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 48.0 | 4.02e-01 | 100.0% | 89.5% |
| 4q4hA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 47.0 | 3.97e-01 | 100.0% | 89.0% |
| 1rtwB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 36.0 | 3.58e-01 | 85.1% | 67.3% |
ECOD (61)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3943464 | 604.5.1.6 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC-like | 0.99 | 94.0 | 9.53e-01 | 96.9% | 98.4% |
| 3963738 | 604.5.1.6 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC-like | 0.97 | 91.0 | 9.30e-01 | 97.4% | 98.4% |
| 3969523 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.96 | 93.0 | 9.37e-01 | 100.0% | 99.5% |
| 3948604 | 604.5.1.6 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC-like | 0.93 | 81.0 | 8.27e-01 | 98.5% | 92.1% |
| 4681797 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.86 | 80.0 | 7.98e-01 | 99.0% | 94.0% |
| 3704239 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.85 | 79.0 | 7.48e-01 | 97.4% | 90.2% |
| 3275250 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.85 | 80.0 | 7.59e-01 | 99.0% | 93.8% |
| 4946592 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 80.0 | 7.77e-01 | 99.0% | 96.2% |
| 5051920 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.73e-01 | 99.5% | 96.7% |
| 4993201 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.56e-01 | 99.0% | 92.7% |
| 3266293 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.83 | 79.0 | 7.25e-01 | 99.0% | 96.2% |
| 3711434 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.83 | 77.0 | 7.29e-01 | 97.4% | 94.2% |
| 4996913 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.70e-01 | 99.0% | 97.1% |
| 4927274 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.60e-01 | 99.0% | 95.7% |
| 3273799 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.82 | 77.0 | 7.04e-01 | 99.0% | 96.8% |
| 3962663 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.82 | 75.0 | 7.44e-01 | 99.0% | 93.5% |
| 4947845 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.82 | 77.0 | 7.34e-01 | 99.0% | 90.9% |
| 4990428 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.81 | 76.0 | 7.32e-01 | 99.5% | 92.7% |
| 5047777 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.81 | 76.0 | 7.56e-01 | 99.0% | 98.5% |
| 3276293 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 75.0 | 7.07e-01 | 99.0% | 92.6% |
| 3715484 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 75.0 | 7.19e-01 | 99.0% | 97.3% |
| 4952953 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.80 | 76.0 | 7.18e-01 | 100.0% | 92.4% |
| 3966581 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.80 | 75.0 | 7.11e-01 | 99.0% | 92.0% |
| 4979857 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.80 | 74.0 | 7.12e-01 | 99.0% | 92.7% |
| 5078457 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.79 | 74.0 | 7.34e-01 | 99.0% | 97.6% |
| 4930881 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.79 | 75.0 | 7.35e-01 | 99.0% | 97.6% |
| 3959931 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.79 | 69.0 | 7.13e-01 | 96.4% | 96.8% |
| 3296552 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.78 | 72.0 | 7.29e-01 | 100.0% | 98.9% |
| 4933975 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.78 | 72.0 | 7.27e-01 | 97.4% | 98.5% |
| 3990051 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.78 | 73.0 | 7.20e-01 | 99.5% | 97.1% |
| 4974443 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.78 | 73.0 | 7.27e-01 | 99.0% | 97.0% |
| 3811048 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.78 | 69.0 | 7.13e-01 | 95.4% | 98.9% |
| 3970616 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.77 | 47.0 | 5.39e-01 | 96.4% | 80.7% |
| 4979497 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.77 | 71.0 | 7.14e-01 | 97.4% | 97.4% |
| 4993153 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.77 | 72.0 | 7.10e-01 | 99.0% | 95.1% |
| 4997151 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.77 | 72.0 | 7.07e-01 | 99.0% | 94.6% |
| 4959725 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.77 | 71.0 | 7.09e-01 | 99.0% | 97.5% |
| 4942906 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.76 | 70.0 | 7.08e-01 | 97.4% | 98.5% |
| 5040281 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.76 | 71.0 | 6.98e-01 | 99.0% | 95.1% |
| 5012985 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.76 | 68.0 | 6.89e-01 | 97.9% | 95.4% |
| 4981135 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.76 | 71.0 | 6.99e-01 | 99.5% | 95.6% |
| 4964547 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.75 | 68.0 | 6.91e-01 | 99.5% | 99.5% |
| 4974436 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.75 | 67.0 | 6.85e-01 | 99.0% | 97.9% |
| 4267497 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.74 | 69.0 | 6.74e-01 | 99.0% | 95.2% |
| 4227779 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.74 | 68.0 | 6.76e-01 | 99.0% | 96.6% |
| 3791 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.72 | 45.0 | 4.55e-01 | 85.1% | 63.7% |
| 5022893 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.67 | 46.0 | 4.64e-01 | 70.3% | 71.0% |
| 3348584 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.62 | 48.0 | 3.84e-01 | 79.5% | 90.8% |
| 3716333 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.59 | 43.0 | 4.22e-01 | 86.7% | 68.8% |
| 3789973 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.58 | 33.0 | 3.97e-01 | 90.8% | 81.5% |
| 4003072 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.57 | 40.0 | 4.51e-01 | 99.0% | 92.7% |
| 4503302 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.54 | 48.0 | 4.12e-01 | 96.9% | 96.8% |
| 3629399 | 1075.4.1.2 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane_2 | 0.53 | 47.0 | 3.88e-01 | 94.4% | 89.4% |
| 3280587 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.53 | 49.0 | 4.07e-01 | 100.0% | 88.5% |
| 3989319 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.53 | 50.0 | 4.17e-01 | 100.0% | 89.1% |
| 3588162 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.52 | 46.0 | 3.90e-01 | 94.4% | 93.1% |
| 3587916 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.52 | 49.0 | 4.11e-01 | 100.0% | 90.8% |
| 4467110 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.52 | 48.0 | 4.03e-01 | 100.0% | 89.1% |
| 3587375 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.52 | 48.0 | 4.09e-01 | 100.0% | 92.6% |
| 5063261 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.51 | 48.0 | 4.02e-01 | 100.0% | 88.9% |
| 4606660 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.51 | 47.0 | 3.99e-01 | 100.0% | 93.9% |
D2
high
residues 508-680
Domain cluster:
representative
CATH (54)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.81 | 76.0 | 7.18e-01 | 99.4% | 99.5% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.80 | 75.0 | 7.00e-01 | 100.0% | 95.3% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.80 | 75.0 | 7.01e-01 | 100.0% | 98.1% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.77 | 54.0 | 5.41e-01 | 100.0% | 70.7% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.76 | 46.0 | 5.80e-01 | 95.4% | 100.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.75 | 46.0 | 5.57e-01 | 99.4% | 93.8% |
| 1st6A01 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.74 | 51.0 | 4.47e-01 | 100.0% | 47.5% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.74 | 52.0 | 5.67e-01 | 100.0% | 86.0% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.72 | 48.0 | 5.68e-01 | 98.3% | 98.3% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.71 | 48.0 | 5.68e-01 | 97.7% | 100.0% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.71 | 49.0 | 5.16e-01 | 100.0% | 77.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 50.0 | 5.62e-01 | 100.0% | 96.9% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.70 | 41.0 | 4.85e-01 | 87.3% | 83.2% |
| 7yu4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 43.0 | 3.77e-01 | 86.1% | 41.6% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.68 | 52.0 | 5.20e-01 | 100.0% | 78.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 47.0 | 5.21e-01 | 100.0% | 92.5% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 48.0 | 4.77e-01 | 98.8% | 71.1% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.66 | 41.0 | 4.79e-01 | 98.3% | 88.9% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.64 | 50.0 | 4.78e-01 | 100.0% | 70.9% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 47.0 | 5.23e-01 | 98.8% | 99.2% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.64 | 43.0 | 4.95e-01 | 99.4% | 95.1% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.62 | 44.0 | 4.40e-01 | 99.4% | 69.2% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.61 | 47.0 | 4.95e-01 | 100.0% | 89.2% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 53.0 | 5.09e-01 | 100.0% | 81.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 42.0 | 4.87e-01 | 98.8% | 100.0% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 57.0 | 4.83e-01 | 100.0% | 94.8% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 45.0 | 4.17e-01 | 77.5% | 83.3% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.59 | 45.0 | 4.70e-01 | 100.0% | 85.8% |
| 3pjaJ01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.59 | 38.0 | 4.32e-01 | 94.8% | 85.5% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.59 | 40.0 | 4.50e-01 | 100.0% | 90.9% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.58 | 34.0 | 3.78e-01 | 85.0% | 69.7% |
| 3m0fB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 37.0 | 4.32e-01 | 96.0% | 90.2% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 40.0 | 4.21e-01 | 97.1% | 80.1% |
| 4fz4A00 | 1.20.140.130 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.56 | 39.0 | 4.14e-01 | 71.1% | 81.2% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 36.0 | 3.88e-01 | 100.0% | 76.6% |
| 5j1gA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 49.0 | 4.47e-01 | 96.0% | 78.1% |
| 3buxB01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.54 | 38.0 | 4.39e-01 | 97.7% | 96.1% |
| 4btfA01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.54 | 32.0 | 4.04e-01 | 78.6% | 100.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 44.0 | 3.95e-01 | 86.1% | 87.4% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 49.0 | 4.06e-01 | 100.0% | 81.6% |
| 3ay5A02 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.53 | 43.0 | 4.39e-01 | 85.5% | 97.0% |
| 1hw1A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 34.0 | 3.67e-01 | 79.2% | 74.2% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 43.0 | 3.95e-01 | 86.1% | 88.1% |
| 5tj5E00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 35.0 | 3.93e-01 | 91.3% | 85.5% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 42.0 | 3.56e-01 | 85.5% | 81.5% |
| 3no6A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.51 | 44.0 | 4.00e-01 | 92.5% | 71.9% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 36.0 | 3.78e-01 | 91.3% | 79.4% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.51 | 47.0 | 4.70e-01 | 100.0% | 99.4% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 47.0 | 3.91e-01 | 98.8% | 75.7% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.69e-01 | 85.5% | 76.9% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.66e-01 | 85.5% | 81.5% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.53e-01 | 85.5% | 78.2% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.50 | 43.0 | 4.01e-01 | 92.5% | 77.1% |
| 2chnB03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.50 | 43.0 | 4.32e-01 | 92.5% | 97.8% |
ECOD (85)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3985523 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.94 | 92.0 | 9.06e-01 | 100.0% | 96.7% |
| 3165047 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.92 | 87.0 | 8.44e-01 | 98.3% | 96.8% |
| 4569731 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.89 | 85.0 | 7.92e-01 | 100.0% | 95.2% |
| 3969522 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.89 | 86.0 | 8.32e-01 | 100.0% | 94.7% |
| 3272683 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.89 | 85.0 | 7.35e-01 | 100.0% | 97.6% |
| 3275250 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.89 | 85.0 | 7.64e-01 | 100.0% | 96.0% |
| 3273799 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.88 | 85.0 | 7.31e-01 | 100.0% | 98.4% |
| 3965437 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.88 | 84.0 | 8.24e-01 | 100.0% | 97.3% |
| 4970819 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.86 | 82.0 | 7.33e-01 | 100.0% | 93.4% |
| 3266289 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.86 | 81.0 | 7.52e-01 | 99.4% | 99.5% |
| 4157336 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.86 | 77.0 | 7.55e-01 | 94.2% | 93.0% |
| 4990428 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.85 | 81.0 | 7.40e-01 | 100.0% | 95.0% |
| 5011234 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.85 | 80.0 | 7.46e-01 | 100.0% | 98.1% |
| 4941651 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.51e-01 | 98.8% | 97.0% |
| 4993201 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 80.0 | 7.29e-01 | 100.0% | 94.5% |
| 4681797 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.84 | 79.0 | 7.50e-01 | 99.4% | 96.0% |
| 4944266 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.23e-01 | 100.0% | 92.7% |
| 4976786 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.35e-01 | 100.0% | 99.0% |
| 5076645 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.13e-01 | 100.0% | 93.8% |
| 4356484 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.84 | 79.0 | 7.36e-01 | 100.0% | 97.1% |
| 3736207 | 604.5.1.16 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2_N | 0.83 | 79.0 | 6.83e-01 | 100.0% | 100.0% |
| 4947845 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.18e-01 | 100.0% | 92.3% |
| 3982841 | 604.5.1.33 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC | 0.83 | 73.0 | 7.65e-01 | 98.8% | 100.0% |
| 5073872 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.20e-01 | 100.0% | 94.4% |
| 4984051 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.21e-01 | 100.0% | 94.9% |
| 5057088 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.83 | 78.0 | 7.27e-01 | 100.0% | 97.6% |
| 3280501 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.82 | 77.0 | 7.20e-01 | 100.0% | 96.2% |
| 3967618 | 604.5.1.33 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC | 0.82 | 78.0 | 7.52e-01 | 100.0% | 98.9% |
| 5082391 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.82 | 76.0 | 7.20e-01 | 98.3% | 99.5% |
| 3959931 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.82 | 77.0 | 7.49e-01 | 98.3% | 96.8% |
| 5044678 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.82 | 77.0 | 7.41e-01 | 100.0% | 100.0% |
| 3734591 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.82 | 77.0 | 6.48e-01 | 100.0% | 99.3% |
| 3689978 | 604.5.1.16 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_2_N | 0.82 | 77.0 | 6.75e-01 | 100.0% | 90.2% |
| 3979458 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.82 | 77.0 | 7.67e-01 | 100.0% | 96.6% |
| 3967683 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.81 | 55.0 | 5.94e-01 | 100.0% | 79.3% |
| 3979467 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.81 | 76.0 | 6.86e-01 | 100.0% | 87.8% |
| 137835 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.81 | 76.0 | 7.11e-01 | 100.0% | 97.1% |
| 5053276 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.81 | 76.0 | 6.95e-01 | 100.0% | 95.0% |
| 3966859 | 604.5.1.33 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC | 0.81 | 76.0 | 7.21e-01 | 100.0% | 96.0% |
| 5031339 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.81 | 75.0 | 7.04e-01 | 100.0% | 97.1% |
| 4941959 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.81 | 75.0 | 7.03e-01 | 100.0% | 95.7% |
| 3579460 | 601.1.3.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › TLN1-like_RS | 0.80 | 54.0 | 5.58e-01 | 100.0% | 72.1% |
| 5082831 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.80 | 74.0 | 7.00e-01 | 100.0% | 98.5% |
| 4033880 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.79 | 74.0 | 7.04e-01 | 99.4% | 99.5% |
| 3964451 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.79 | 75.0 | 7.11e-01 | 100.0% | 89.5% |
| 4032906 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.79 | 62.0 | 6.83e-01 | 93.1% | 100.0% |
| 5065831 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.79 | 74.0 | 6.99e-01 | 100.0% | 98.0% |
| 3761465 | 601.1.1.104 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › 4HB_KIF14 | 0.78 | 55.0 | 5.81e-01 | 100.0% | 80.0% |
| 3253936 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.78 | 52.0 | 5.86e-01 | 100.0% | 86.7% |
| 4479929 | 601.1.1.89 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › FUSC | 0.78 | 73.0 | 7.00e-01 | 100.0% | 94.9% |
| 3774605 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.78 | 52.0 | 5.21e-01 | 100.0% | 65.6% |
| 5012984 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.78 | 72.0 | 7.03e-01 | 100.0% | 97.9% |
| 4949599 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.77 | 56.0 | 6.16e-01 | 100.0% | 89.0% |
| 5026318 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.77 | 72.0 | 7.05e-01 | 100.0% | 99.5% |
| 4009779 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.77 | 53.0 | 5.91e-01 | 100.0% | 89.6% |
| 3562194 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 51.0 | 5.38e-01 | 100.0% | 74.7% |
| 4393627 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.76 | 68.0 | 6.94e-01 | 98.8% | 97.1% |
| 5063573 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.76 | 71.0 | 6.98e-01 | 100.0% | 100.0% |
| 3975942 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.76 | 49.0 | 5.63e-01 | 100.0% | 86.9% |
| 4987042 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.76 | 54.0 | 5.98e-01 | 100.0% | 92.6% |
| 4009847 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 68.0 | 6.91e-01 | 98.8% | 97.1% |
| 4001486 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.76 | 53.0 | 5.43e-01 | 100.0% | 74.5% |
| 4360597 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.74 | 68.0 | 6.90e-01 | 98.8% | 99.4% |
| 3966166 | 601.4.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PilJ | 0.74 | 51.0 | 5.80e-01 | 100.0% | 93.1% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.71 | 51.0 | 5.60e-01 | 100.0% | 91.4% |
| 3953242 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.69 | 42.0 | 4.10e-01 | 90.8% | 55.7% |
| 3889629 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.68 | 48.0 | 4.62e-01 | 100.0% | 63.6% |
| 4026297 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.68 | 46.0 | 5.11e-01 | 100.0% | 87.4% |
| 3692058 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 51.0 | 5.44e-01 | 100.0% | 91.3% |
| 3727421 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 48.0 | 4.99e-01 | 99.4% | 81.2% |
| 3563976 | 601.4.1.79 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_KIF14 | 0.63 | 55.0 | 5.71e-01 | 100.0% | 98.8% |
| 3236795 | 601.16.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT | 0.62 | 43.0 | 4.71e-01 | 100.0% | 87.9% |
| 4154423 | 192.29.1.104 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 | 0.58 | 52.0 | 5.15e-01 | 100.0% | 93.3% |
| 4956385 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 51.0 | 5.10e-01 | 100.0% | 94.9% |
| 3713307 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 45.0 | 4.82e-01 | 96.5% | 97.4% |
| 4481861 | 150.8.1.5 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › EspA_EspE | 0.54 | 43.0 | 4.11e-01 | 85.0% | 79.0% |
| 4012137 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.53 | 38.0 | 4.28e-01 | 100.0% | 94.1% |
| 5017125 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.53 | 38.0 | 3.62e-01 | 93.6% | 62.5% |
| 3925122 | 4177.1.1.4 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD | 0.53 | 43.0 | 3.99e-01 | 85.5% | 76.4% |
| 5065873 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 37.0 | 3.54e-01 | 94.2% | 61.0% |
| 3502594 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.51 | 46.0 | 4.24e-01 | 94.2% | 84.5% |
| 3539434 | 633.21.1.40 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › AGMP_C | 0.51 | 38.0 | 3.88e-01 | 92.5% | 80.0% |
| 3396625 | 4177.1.1.12 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 | 0.51 | 41.0 | 3.75e-01 | 85.5% | 80.0% |
| 4997380 | 3543.1.1.0 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel | 0.51 | 47.0 | 4.64e-01 | 99.4% | 98.3% |
| 3268765 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.50 | 41.0 | 3.66e-01 | 86.1% | 78.3% |
D3
medium
residues 1-133
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12805.14 best | FUSC-like | 101.0 | 9.40e-29 | 73.7% | 34.2% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5zzjA02 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.67 | 50.0 | 3.84e-01 | 78.2% | 89.8% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.66 | 32.0 | 3.46e-01 | 100.0% | 53.6% |
| 4gbjC02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.64 | 38.0 | 3.87e-01 | 72.9% | 58.5% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.64 | 38.0 | 4.72e-01 | 97.0% | 100.0% |
| 1vpdA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.64 | 38.0 | 3.90e-01 | 73.7% | 60.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 33.0 | 3.69e-01 | 79.7% | 61.7% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.61 | 30.0 | 4.12e-01 | 78.2% | 95.3% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.61 | 47.0 | 4.63e-01 | 79.7% | 98.6% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.60 | 52.0 | 4.77e-01 | 93.2% | 89.1% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.60 | 45.0 | 4.03e-01 | 78.9% | 74.3% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.56 | 43.0 | 3.66e-01 | 79.7% | 82.9% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 34.0 | 3.94e-01 | 89.5% | 83.5% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.56 | 40.0 | 3.46e-01 | 72.9% | 90.0% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 42.0 | 3.20e-01 | 79.7% | 100.0% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 44.0 | 4.48e-01 | 84.2% | 90.8% |
| 3zgzA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.55 | 38.0 | 3.48e-01 | 70.7% | 61.0% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 34.0 | 3.85e-01 | 78.2% | 83.8% |
| 3zojA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.54 | 39.0 | 3.15e-01 | 74.4% | 58.2% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.54 | 40.0 | 3.00e-01 | 75.9% | 84.6% |
| 4pypA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 45.0 | 3.13e-01 | 91.0% | 73.6% |
| 4iu9A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.54 | 46.0 | 3.28e-01 | 93.2% | 74.2% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.53 | 39.0 | 3.92e-01 | 77.4% | 99.3% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.53 | 37.0 | 3.57e-01 | 89.5% | 62.9% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 47.0 | 3.58e-01 | 100.0% | 40.9% |
| 2qgsB01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.52 | 30.0 | 3.59e-01 | 79.7% | 85.2% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.52 | 36.0 | 3.65e-01 | 97.0% | 70.6% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 35.0 | 3.75e-01 | 88.0% | 79.5% |
| 6bfnB02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.52 | 41.0 | 3.58e-01 | 84.2% | 77.2% |
| 2i2oA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 37.0 | 3.18e-01 | 74.4% | 70.1% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 45.0 | 3.96e-01 | 94.0% | 79.9% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 39.0 | 4.08e-01 | 79.7% | 96.7% |
| 1or4B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 35.0 | 3.38e-01 | 71.4% | 58.2% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 45.0 | 3.65e-01 | 95.5% | 75.5% |
| 7d5qA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.51 | 44.0 | 4.02e-01 | 95.5% | 84.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 31.0 | 3.50e-01 | 78.9% | 78.4% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3967350 | 593.1.1.2 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › FUSC_2 | 0.84 | 74.0 | 5.64e-01 | 96.2% | 43.5% |
| 3175660 | 5067.1.1.14 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › FUSC_2 | 0.76 | 70.0 | 5.14e-01 | 99.2% | 41.2% |
| 3264196 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.75 | 70.0 | 6.46e-01 | 100.0% | 86.1% |
| 3337402 | 5067.1.1.14 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › FUSC_2 | 0.75 | 67.0 | 4.96e-01 | 98.5% | 38.5% |
| 3297362 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.74 | 68.0 | 6.31e-01 | 99.2% | 87.3% |
| 4238557 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.72 | 62.0 | 5.58e-01 | 93.2% | 85.6% |
| 4071531 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.72 | 64.0 | 5.68e-01 | 96.2% | 84.9% |
| 3600444 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.69 | 62.0 | 6.04e-01 | 97.7% | 89.7% |
| 4590703 | 5050.1.1.54 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Mntp | 0.68 | 61.0 | 5.32e-01 | 95.5% | 87.7% |
| 5003109 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.68 | 58.0 | 4.92e-01 | 94.7% | 84.9% |
| 4676221 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.67 | 60.0 | 5.31e-01 | 96.2% | 83.5% |
| 3978910 | 5050.1.1.53 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC | 0.66 | 59.0 | 5.15e-01 | 97.0% | 83.5% |
| 3614444 | 593.1.1.0 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like | 0.65 | 56.0 | 4.54e-01 | 94.0% | 77.2% |
| 3624122 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 46.0 | 4.16e-01 | 74.4% | 55.0% |
| 3242658 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 49.0 | 3.43e-01 | 89.5% | 59.3% |
| 3670870 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.59 | 41.0 | 3.83e-01 | 71.4% | 74.1% |
| 4997271 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.59 | 44.0 | 3.59e-01 | 77.4% | 78.4% |
| 3189063 | 3542.1.1.3 ↗ | alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B | 0.58 | 44.0 | 3.59e-01 | 79.7% | 88.5% |
| 3596978 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.58 | 43.0 | 3.67e-01 | 78.2% | 73.8% |
| 3964811 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.58 | 47.0 | 4.11e-01 | 86.5% | 93.5% |
| 3530101 | 601.19.1.17 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Niban2 | 0.58 | 46.0 | 3.77e-01 | 86.5% | 98.9% |
| 3779599 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.58 | 40.0 | 2.81e-01 | 71.4% | 48.5% |
| 3271841 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.58 | 51.0 | 3.74e-01 | 99.2% | 90.6% |
| 4991155 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.58 | 47.0 | 4.16e-01 | 90.2% | 68.3% |
| 4173524 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.57 | 39.0 | 3.36e-01 | 70.7% | 87.3% |
| 5028782 | 5073.1.2.0 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain | 0.57 | 44.0 | 3.81e-01 | 82.0% | 59.5% |
| 3980685 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.56 | 42.0 | 3.66e-01 | 79.7% | 52.6% |
| 4043079 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.53 | 40.0 | 3.54e-01 | 79.7% | 70.0% |
| 3248267 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 39.0 | 3.79e-01 | 75.2% | 100.0% |
| 3668007 | 601.51.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-helical domain in phase 1 flagellin › alpha-helical domain in phase 1 flagellin | 0.53 | 43.0 | 3.54e-01 | 88.7% | 90.8% |
| 4982330 | 3355.1.1.41 ↗ | alpha complex topology › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › dicarboxylate/sodium symporter › DUF401 | 0.53 | 45.0 | 3.32e-01 | 96.2% | 91.1% |
| 3319315 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 41.0 | 3.37e-01 | 85.7% | 90.9% |
| 3952630 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.53 | 33.0 | 3.25e-01 | 79.7% | 58.6% |
| 3634278 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 44.0 | 3.67e-01 | 91.7% | 81.1% |
| 3790837 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 36.0 | 3.59e-01 | 88.7% | 69.6% |
| 3280873 | 5050.1.1.60 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 | 0.52 | 46.0 | 3.98e-01 | 99.2% | 81.0% |
| 3394243 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 41.0 | 3.50e-01 | 85.0% | 58.6% |
| 4941191 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 35.0 | 3.88e-01 | 88.7% | 85.5% |
| 3727666 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 45.0 | 3.69e-01 | 97.0% | 66.0% |
| 5069594 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 40.0 | 3.47e-01 | 85.0% | 95.8% |
| 4544919 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.51 | 38.0 | 3.28e-01 | 79.7% | 71.7% |
| 4994917 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.50 | 33.0 | 2.72e-01 | 78.2% | 36.3% |
| 3586751 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.50 | 32.0 | 2.95e-01 | 78.9% | 47.8% |
D4
medium
residues 387-502
Domain cluster:
rep: CAKLQF020000005.1__CAH1078001.1__SAMEA5780031_01189__00037__D15-170
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13515.13 best | FUSC_2 | 91.9 | 4.90e-26 | 97.4% | 89.7% |
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 40.0 | 4.14e-01 | 87.9% | 52.3% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 39.0 | 3.04e-01 | 87.1% | 24.1% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.78 | 56.0 | 4.47e-01 | 75.0% | 50.9% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 46.0 | 4.57e-01 | 94.0% | 59.5% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.74 | 46.0 | 4.17e-01 | 94.0% | 47.4% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.68 | 44.0 | 4.47e-01 | 100.0% | 66.1% |
| 4oh3A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.67 | 60.0 | 3.91e-01 | 99.1% | 85.4% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.66 | 35.0 | 4.53e-01 | 86.2% | 93.8% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.64 | 38.0 | 3.44e-01 | 96.6% | 43.6% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.64 | 47.0 | 4.86e-01 | 97.4% | 82.2% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.64 | 37.0 | 3.92e-01 | 94.8% | 62.3% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 40.0 | 3.13e-01 | 87.9% | 29.7% |
| 2oebA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.62 | 55.0 | 5.07e-01 | 98.3% | 96.7% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 42.0 | 4.45e-01 | 96.6% | 82.2% |
| 3ulkA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.60 | 44.0 | 3.37e-01 | 77.6% | 74.7% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 36.0 | 4.11e-01 | 92.2% | 81.2% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.59 | 35.0 | 3.53e-01 | 74.1% | 56.9% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.59 | 50.0 | 4.14e-01 | 90.5% | 73.8% |
| 3bniB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 42.0 | 3.72e-01 | 74.1% | 56.7% |
| 2v6eA02 | 1.20.1440.270 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 49.0 | 4.73e-01 | 98.3% | 81.4% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.58 | 47.0 | 5.09e-01 | 87.9% | 100.0% |
| 2v0pA00 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.58 | 40.0 | 3.31e-01 | 71.6% | 92.7% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.57 | 45.0 | 3.75e-01 | 84.5% | 96.2% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.57 | 32.0 | 3.99e-01 | 86.2% | 98.4% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.57 | 41.0 | 3.57e-01 | 75.0% | 80.9% |
| 5ziyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.57 | 45.0 | 3.82e-01 | 85.3% | 80.9% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.56 | 46.0 | 3.80e-01 | 86.2% | 62.5% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.56 | 34.0 | 3.99e-01 | 87.9% | 88.3% |
| 2xzeB00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 45.0 | 4.23e-01 | 83.6% | 81.9% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 46.0 | 4.52e-01 | 86.2% | 100.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.56 | 45.0 | 4.61e-01 | 86.2% | 94.7% |
| 2di3B02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.55 | 43.0 | 3.96e-01 | 83.6% | 92.3% |
| 1tqgA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 43.0 | 4.51e-01 | 83.6% | 99.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 37.0 | 3.94e-01 | 97.4% | 81.4% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 44.0 | 3.96e-01 | 86.2% | 79.1% |
| 2qw6D00 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.54 | 33.0 | 3.81e-01 | 77.6% | 83.7% |
| 3kyiA00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.53 | 44.0 | 4.27e-01 | 87.1% | 79.7% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.53 | 47.0 | 4.02e-01 | 99.1% | 91.1% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.52 | 42.0 | 4.07e-01 | 86.2% | 87.0% |
| 3o7pA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 46.0 | 3.81e-01 | 100.0% | 66.1% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.52 | 37.0 | 3.18e-01 | 87.1% | 45.1% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.51 | 36.0 | 3.22e-01 | 72.4% | 73.8% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.51 | 42.0 | 4.00e-01 | 86.2% | 98.5% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 37.0 | 3.47e-01 | 75.0% | 76.9% |
| 6tqpA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 38.0 | 3.63e-01 | 79.3% | 69.1% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.51 | 36.0 | 4.06e-01 | 87.9% | 97.7% |
ECOD (72)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3696827 | 604.5.1.27 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › FUSC_2 | 0.87 | 83.0 | 4.85e-01 | 100.0% | 17.3% |
| 3967350 | 593.1.1.2 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › FUSC_2 | 0.86 | 81.0 | 5.87e-01 | 100.0% | 40.4% |
| 3834034 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.86 | 81.0 | 7.08e-01 | 100.0% | 78.2% |
| 3805429 | 3562.1.1.33 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › ALMT | 0.86 | 81.0 | 7.14e-01 | 100.0% | 80.6% |
| 3663646 | 7064.1.1.5 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT | 0.85 | 77.0 | 7.55e-01 | 96.6% | 100.0% |
| 3367916 | 5067.1.1.13 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT | 0.85 | 77.0 | 6.88e-01 | 96.6% | 80.0% |
| 4995144 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.79 | 57.0 | 4.82e-01 | 74.1% | 52.5% |
| 3488340 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.76 | 48.0 | 4.91e-01 | 93.1% | 65.2% |
| 3696174 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 53.0 | 5.01e-01 | 75.0% | 69.3% |
| 3239453 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.73 | 47.0 | 4.46e-01 | 93.1% | 55.6% |
| 3720301 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 51.0 | 4.21e-01 | 71.6% | 49.7% |
| 3947999 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 55.0 | 4.45e-01 | 77.6% | 48.1% |
| 4011226 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.73 | 53.0 | 4.40e-01 | 75.0% | 48.5% |
| 3968770 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 55.0 | 4.44e-01 | 77.6% | 47.1% |
| 3600444 | 7064.1.1.0 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 | 0.73 | 64.0 | 5.96e-01 | 95.7% | 79.3% |
| 3599164 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 50.0 | 4.03e-01 | 71.6% | 46.2% |
| 4521983 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 54.0 | 4.27e-01 | 77.6% | 43.5% |
| 3209464 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 51.0 | 4.24e-01 | 72.4% | 55.4% |
| 4149653 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 50.0 | 4.50e-01 | 71.6% | 60.4% |
| 4032838 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.71 | 51.0 | 4.41e-01 | 75.0% | 50.0% |
| 3386417 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.71 | 54.0 | 4.42e-01 | 80.2% | 58.1% |
| 3170919 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.71 | 53.0 | 4.34e-01 | 77.6% | 49.8% |
| 3732054 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 49.0 | 4.18e-01 | 72.4% | 52.6% |
| 3189912 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 51.0 | 4.16e-01 | 75.0% | 50.5% |
| 3608820 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 50.0 | 4.09e-01 | 75.0% | 48.4% |
| 3886185 | 5050.1.1.10 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 | 0.69 | 51.0 | 4.01e-01 | 77.6% | 40.8% |
| 4977940 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 48.0 | 4.02e-01 | 71.6% | 46.5% |
| 3948660 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 52.0 | 4.33e-01 | 78.4% | 62.6% |
| 5038416 | 604.39.1.12 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › VTT_dom | 0.69 | 51.0 | 4.50e-01 | 77.6% | 91.8% |
| 5042408 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.69 | 36.0 | 3.78e-01 | 87.1% | 53.6% |
| 3785394 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.69 | 55.0 | 4.13e-01 | 84.5% | 49.5% |
| 3388186 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 51.0 | 4.24e-01 | 78.4% | 59.8% |
| 3986576 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 51.0 | 3.87e-01 | 77.6% | 67.0% |
| 3785076 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.68 | 60.0 | 3.94e-01 | 96.6% | 78.4% |
| 4446033 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 55.0 | 4.68e-01 | 87.1% | 66.3% |
| 3692484 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.68 | 48.0 | 3.99e-01 | 74.1% | 47.6% |
| 4937680 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 50.0 | 4.29e-01 | 77.6% | 53.5% |
| 3849657 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.67 | 53.0 | 5.68e-01 | 100.0% | 97.0% |
| 4955945 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.67 | 52.0 | 4.55e-01 | 81.0% | 62.9% |
| 3971899 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.66 | 51.0 | 4.24e-01 | 81.0% | 59.1% |
| 4382712 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 49.0 | 4.07e-01 | 77.6% | 56.7% |
| 4017945 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 47.0 | 3.93e-01 | 75.0% | 51.2% |
| 5024587 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.65 | 49.0 | 4.26e-01 | 79.3% | 56.1% |
| 3733862 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.63 | 53.0 | 4.18e-01 | 88.8% | 54.8% |
| 3192700 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 54.0 | 4.04e-01 | 92.2% | 48.9% |
| 3638377 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 51.0 | 4.06e-01 | 90.5% | 56.2% |
| 4963714 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 50.0 | 4.12e-01 | 87.1% | 92.5% |
| 3735606 | 5050.1.1.12 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TRI12 | 0.61 | 52.0 | 4.09e-01 | 92.2% | 54.2% |
| 3490044 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.61 | 45.0 | 4.33e-01 | 96.6% | 68.5% |
| 5001317 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.60 | 42.0 | 3.46e-01 | 71.6% | 40.0% |
| 3237028 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 49.0 | 4.06e-01 | 87.9% | 90.2% |
| 3714315 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 40.0 | 4.15e-01 | 96.6% | 75.2% |
| 3973571 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.59 | 53.0 | 5.35e-01 | 98.3% | 99.1% |
| 5066104 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.59 | 35.0 | 2.31e-01 | 86.2% | 12.6% |
| 5054547 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.58 | 38.0 | 3.70e-01 | 70.7% | 60.0% |
| 4554168 | 1079.1.1.13 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Mntp | 0.58 | 52.0 | 4.55e-01 | 100.0% | 81.7% |
| 3686864 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 50.0 | 3.82e-01 | 95.7% | 63.7% |
| 4954845 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 38.0 | 4.14e-01 | 94.8% | 80.0% |
| 3829773 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.56 | 50.0 | 4.03e-01 | 99.1% | 89.3% |
| None | — | 0.56 | 39.0 | 3.21e-01 | 71.6% | 40.5% | |
| 4024003 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 44.0 | 4.13e-01 | 86.2% | 92.4% |
| 4992414 | 140.1.1.14 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e | 0.55 | 40.0 | 3.64e-01 | 85.3% | 56.8% |
| 3218650 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 39.0 | 4.15e-01 | 96.6% | 83.8% |
| 3899959 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 41.0 | 4.30e-01 | 96.6% | 88.6% |
| 3378097 | 604.1.1.110 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › WIT1_2_N | 0.54 | 42.0 | 4.24e-01 | 94.8% | 80.8% |
| 3939816 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.53 | 41.0 | 4.05e-01 | 94.0% | 78.3% |
| 3412171 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.53 | 39.0 | 2.55e-01 | 76.7% | 83.3% |
| 5070669 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 47.0 | 3.88e-01 | 100.0% | 68.8% |
| 3194462 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 45.0 | 3.76e-01 | 97.4% | 89.0% |
| 4302177 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.52 | 39.0 | 3.74e-01 | 84.5% | 65.7% |
| 4992667 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.51 | 41.0 | 3.15e-01 | 87.9% | 90.9% |
| 4062922 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.51 | 35.0 | 3.36e-01 | 70.7% | 60.7% |