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CAKLQF020000003.1__CAH1076593.1__SAMEA5780031_00858__00185
Bact-VirCAKLQF020000003.1__CAH1076593.1__SAMEA5780031_00858__00185
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-124
Domain cluster:
rep: CAKLQF020000002.1__CAH1073693.1__SAMEA5780031_00629__00258__D1-117
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.74 | 51.0 | 5.63e-01 | 80.6% | 86.3% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 42.0 | 4.86e-01 | 75.8% | 85.1% |
| 4tkrA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.65 | 51.0 | 4.49e-01 | 83.9% | 69.4% |
| 5tpmB00 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.63 | 52.0 | 5.02e-01 | 97.6% | 77.3% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 45.0 | 4.73e-01 | 73.4% | 90.2% |
| 3mk7A00 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.62 | 51.0 | 3.45e-01 | 88.7% | 79.2% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.62 | 48.0 | 4.04e-01 | 84.7% | 71.7% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 44.0 | 4.65e-01 | 74.2% | 91.6% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 40.0 | 3.76e-01 | 74.2% | 88.0% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 39.0 | 3.64e-01 | 70.2% | 61.7% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.56 | 37.0 | 3.50e-01 | 90.3% | 53.5% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.55 | 46.0 | 4.57e-01 | 97.6% | 85.7% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.54 | 42.0 | 4.55e-01 | 89.5% | 98.1% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.54 | 40.0 | 4.39e-01 | 77.4% | 94.1% |
| 2iu5B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 41.0 | 3.70e-01 | 91.1% | 58.2% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.53 | 30.0 | 3.26e-01 | 73.4% | 66.0% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 30.0 | 3.82e-01 | 75.0% | 97.3% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.52 | 40.0 | 4.36e-01 | 90.3% | 99.0% |
| 6nplA01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.52 | 44.0 | 3.00e-01 | 92.7% | 98.5% |
| 3o10C00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 45.0 | 4.43e-01 | 95.2% | 96.3% |
| 4akgA16 | 1.10.8.720 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Region D6 of dynein motor | 0.52 | 45.0 | 4.14e-01 | 96.8% | 94.5% |
| 4c3eM00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.52 | 40.0 | 3.77e-01 | 88.7% | 66.5% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.51 | 36.0 | 4.01e-01 | 80.6% | 93.8% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 44.0 | 3.87e-01 | 93.5% | 72.2% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.50 | 44.0 | 4.33e-01 | 94.4% | 89.3% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.50 | 42.0 | 4.20e-01 | 93.5% | 87.7% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3390957 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.73 | 51.0 | 5.40e-01 | 79.0% | 80.0% |
| 4032540 | 5069.1.3.10 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I | 0.73 | 48.0 | 5.14e-01 | 73.4% | 76.4% |
| 3985992 | 5069.1.3.10 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I | 0.72 | 49.0 | 5.62e-01 | 71.0% | 94.4% |
| 3671591 | 5058.1.1.38 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MSL2_3 | 0.72 | 48.0 | 5.21e-01 | 71.8% | 81.0% |
| 4027655 | 5069.1.3.23 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DAD | 0.71 | 45.0 | 5.01e-01 | 71.0% | 80.0% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.70 | 52.0 | 5.53e-01 | 79.0% | 87.2% |
| 4024245 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.69 | 35.0 | 3.45e-01 | 71.0% | 45.4% |
| 4982132 | 5069.1.3.135 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF5985 | 0.69 | 43.0 | 4.89e-01 | 71.8% | 83.0% |
| 3266856 | 5001.1.1.31 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM | 0.67 | 60.0 | 4.59e-01 | 96.0% | 78.8% |
| 4947364 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.66 | 44.0 | 4.92e-01 | 77.4% | 87.4% |
| 3220791 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.64 | 54.0 | 4.68e-01 | 91.1% | 86.3% |
| 4999330 | 604.12.1.135 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Oxidored_q2 | 0.61 | 40.0 | 4.43e-01 | 76.6% | 83.0% |
| 3445635 | 3718.1.1.23 ↗ | alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › ALMT | 0.60 | 39.0 | 4.05e-01 | 73.4% | 70.4% |
| 4015782 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 41.0 | 3.54e-01 | 70.2% | 64.3% |
| 3440522 | 5069.1.3.12 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF6490 | 0.59 | 40.0 | 4.48e-01 | 70.2% | 95.8% |
| 3621071 | 3755.4.1.31 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Fry_C | 0.58 | 48.0 | 4.18e-01 | 91.9% | 81.0% |
| 4409034 | 3843.1.1.1 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 | 0.58 | 42.0 | 4.48e-01 | 76.6% | 90.9% |
| 3802336 | 3711.1.1.4 ↗ | alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › DOG1 | 0.56 | 46.0 | 3.94e-01 | 92.7% | 96.3% |
| 4024734 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.55 | 42.0 | 3.83e-01 | 93.5% | 60.6% |
| 5008061 | 1075.1.1.67 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 | 0.54 | 39.0 | 3.41e-01 | 79.0% | 47.7% |
| 3837728 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.54 | 45.0 | 4.39e-01 | 91.1% | 91.1% |
| 5074225 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.54 | 36.0 | 4.13e-01 | 72.6% | 93.3% |
| 3673192 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 46.0 | 4.13e-01 | 92.7% | 70.0% |
| 3821523 | 5069.1.3.122 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › PLAC8 | 0.53 | 39.0 | 4.07e-01 | 96.8% | 82.6% |
| 4028568 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.53 | 46.0 | 4.26e-01 | 94.4% | 82.6% |
| 5071763 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.53 | 46.0 | 4.28e-01 | 95.2% | 87.6% |
| 3849157 | 192.29.1.11 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA | 0.52 | 45.0 | 4.50e-01 | 93.5% | 91.2% |
| 3456226 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 45.0 | 3.56e-01 | 96.0% | 46.9% |
| 3627220 | 1075.5.1.5 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Rft-1 | 0.51 | 41.0 | 3.56e-01 | 85.5% | 85.3% |
| 4589611 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.51 | 40.0 | 3.52e-01 | 86.3% | 90.3% |
| 3388850 | 109.4.1.228 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C | 0.51 | 36.0 | 2.60e-01 | 73.4% | 44.2% |
| 5057381 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.50 | 33.0 | 3.90e-01 | 74.2% | 97.6% |
D2
medium
residues 125-225
Domain cluster:
representative
CATH (45)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.75 | 52.0 | 4.11e-01 | 81.2% | 35.6% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.75 | 56.0 | 4.18e-01 | 78.2% | 79.3% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.75 | 58.0 | 5.86e-01 | 91.1% | 82.4% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.70 | 53.0 | 4.73e-01 | 99.0% | 57.4% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 48.0 | 4.07e-01 | 71.3% | 78.5% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.68 | 48.0 | 4.05e-01 | 73.3% | 70.2% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.67 | 50.0 | 5.46e-01 | 99.0% | 95.2% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.67 | 51.0 | 3.86e-01 | 82.2% | 74.3% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.64 | 49.0 | 4.97e-01 | 100.0% | 82.0% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.62 | 43.0 | 4.26e-01 | 72.3% | 76.4% |
| 2o7gA00 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.62 | 43.0 | 4.59e-01 | 96.0% | 84.1% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.62 | 43.0 | 3.76e-01 | 89.1% | 47.1% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.62 | 46.0 | 4.21e-01 | 78.2% | 87.8% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 39.0 | 3.20e-01 | 73.3% | 34.6% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.60 | 54.0 | 4.46e-01 | 100.0% | 64.7% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.60 | 53.0 | 4.89e-01 | 99.0% | 75.6% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.60 | 44.0 | 4.11e-01 | 91.1% | 62.1% |
| 2i0mA02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 41.0 | 4.13e-01 | 70.3% | 72.3% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.59 | 36.0 | 3.80e-01 | 70.3% | 67.4% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.59 | 52.0 | 4.81e-01 | 99.0% | 77.4% |
| 1ldjA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.59 | 43.0 | 4.04e-01 | 76.2% | 73.6% |
| 3on2A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 41.0 | 3.34e-01 | 71.3% | 50.0% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.58 | 33.0 | 3.65e-01 | 79.2% | 67.9% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.58 | 52.0 | 4.24e-01 | 100.0% | 61.3% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 44.0 | 3.74e-01 | 80.2% | 65.5% |
| 2xzeB00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 42.0 | 3.78e-01 | 75.2% | 84.8% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.57 | 48.0 | 4.63e-01 | 100.0% | 79.0% |
| 2oezA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.57 | 53.0 | 4.45e-01 | 100.0% | 89.6% |
| 2nwbA02 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 40.0 | 3.10e-01 | 74.3% | 48.1% |
| 1gcvB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 42.0 | 3.83e-01 | 78.2% | 77.2% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 41.0 | 3.61e-01 | 87.1% | 51.6% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.55 | 48.0 | 4.60e-01 | 99.0% | 84.2% |
| 4h7nA01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.55 | 44.0 | 3.22e-01 | 87.1% | 53.8% |
| 6wk3A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 42.0 | 3.73e-01 | 83.2% | 75.2% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.54 | 46.0 | 4.45e-01 | 95.0% | 81.2% |
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 46.0 | 4.50e-01 | 100.0% | 88.4% |
| 3hj1A01 | 1.10.1410.10 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › | 0.53 | 45.0 | 3.42e-01 | 95.0% | 53.4% |
| 3eupB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 39.0 | 3.15e-01 | 78.2% | 58.0% |
| 2dg7A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 37.0 | 3.10e-01 | 73.3% | 83.9% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.52 | 36.0 | 3.21e-01 | 72.3% | 89.7% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.52 | 46.0 | 4.43e-01 | 100.0% | 83.8% |
| 4o6mA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.51 | 42.0 | 3.44e-01 | 91.1% | 65.6% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 40.0 | 3.10e-01 | 87.1% | 80.4% |
| 3rfyA02 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.51 | 46.0 | 4.52e-01 | 100.0% | 95.3% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 38.0 | 3.42e-01 | 81.2% | 92.5% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4579424 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.76 | 57.0 | 4.24e-01 | 78.2% | 37.5% |
| 5019542 | 622.4.1.67 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 | 0.75 | 55.0 | 5.62e-01 | 76.2% | 79.8% |
| 4009028 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.75 | 58.0 | 5.52e-01 | 83.2% | 80.8% |
| 3913850 | 601.19.1.5 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PBC (DEPRECATED) | 0.74 | 56.0 | 5.17e-01 | 78.2% | 74.4% |
| 3985992 | 5069.1.3.10 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › ATP-synt_I | 0.74 | 56.0 | 5.95e-01 | 80.2% | 90.0% |
| 3170937 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.74 | 57.0 | 4.15e-01 | 82.2% | 80.4% |
| 3725261 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.73 | 57.0 | 4.01e-01 | 82.2% | 74.6% |
| 3390957 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.73 | 58.0 | 5.68e-01 | 91.1% | 79.1% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.72 | 58.0 | 5.73e-01 | 94.1% | 80.7% |
| 3220791 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.71 | 65.0 | 5.26e-01 | 100.0% | 85.8% |
| 4983374 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.71 | 53.0 | 4.86e-01 | 78.2% | 86.9% |
| 3191997 | 5041.1.1.15 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Tmemb_170 | 0.71 | 56.0 | 5.48e-01 | 84.2% | 90.9% |
| 3270091 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.71 | 51.0 | 4.08e-01 | 76.2% | 82.9% |
| 4639947 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.70 | 51.0 | 4.03e-01 | 76.2% | 68.1% |
| 3605313 | 4010.1.1.2 ↗ | a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 | 0.70 | 48.0 | 3.10e-01 | 71.3% | 17.0% |
| 3475800 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.70 | 57.0 | 5.55e-01 | 94.1% | 80.9% |
| 3494796 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 53.0 | 3.91e-01 | 82.2% | 74.8% |
| 3973819 | 191.1.1.21 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_18 | 0.67 | 47.0 | 4.11e-01 | 76.2% | 50.3% |
| 4608312 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.66 | 48.0 | 3.63e-01 | 76.2% | 32.4% |
| 3252760 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.65 | 45.0 | 4.37e-01 | 71.3% | 69.3% |
| 5030487 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.65 | 49.0 | 3.94e-01 | 82.2% | 47.6% |
| 4983511 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.64 | 53.0 | 4.71e-01 | 92.1% | 84.7% |
| 5065578 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.63 | 44.0 | 3.48e-01 | 71.3% | 70.0% |
| 4997694 | 3877.1.2.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › DUF106 › EMC3_TMCO1 | 0.63 | 44.0 | 3.69e-01 | 71.3% | 66.3% |
| 5083305 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.60 | 43.0 | 3.86e-01 | 75.2% | 83.4% |
| 4321934 | 101.1.2.311 ↗ | alpha arrays › HTH › HTH › winged helix domain › RNA12 | 0.60 | 45.0 | 3.88e-01 | 79.2% | 93.1% |
| 1549356 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.60 | 53.0 | 4.89e-01 | 99.0% | 75.6% |
| 1503807 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 54.0 | 5.21e-01 | 100.0% | 90.4% |
| 3579241 | 192.29.1.50 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PTPLA | 0.60 | 53.0 | 5.15e-01 | 100.0% | 91.3% |
| 3257705 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.59 | 44.0 | 4.53e-01 | 88.1% | 83.2% |
| 4467738 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.59 | 39.0 | 4.12e-01 | 91.1% | 75.6% |
| 3395695 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.59 | 51.0 | 3.58e-01 | 96.0% | 84.0% |
| 3335074 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 47.0 | 4.29e-01 | 86.1% | 67.7% |
| 3235128 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.57 | 48.0 | 4.55e-01 | 95.0% | 76.8% |
| 4021337 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.55 | 42.0 | 3.10e-01 | 79.2% | 78.8% |
| 5055769 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 41.0 | 4.53e-01 | 82.2% | 98.8% |
| 4600613 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 48.0 | 4.47e-01 | 100.0% | 89.2% |
| 4972405 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.55 | 46.0 | 3.28e-01 | 92.1% | 31.3% |
| 3799233 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.54 | 42.0 | 3.73e-01 | 83.2% | 95.2% |
| 5024703 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.54 | 43.0 | 3.48e-01 | 84.2% | 76.8% |
| 3391724 | 109.1.1.7 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_3 | 0.54 | 39.0 | 3.35e-01 | 75.2% | 72.1% |
| 3934749 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.53 | 43.0 | 3.97e-01 | 89.1% | 71.1% |
| 3934572 | 109.1.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 | 0.53 | 38.0 | 3.24e-01 | 75.2% | 68.2% |
| 5039485 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.52 | 40.0 | 3.28e-01 | 84.2% | 77.0% |
| 4949471 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.51 | 39.0 | 3.32e-01 | 82.2% | 82.9% |
| 3730903 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.51 | 45.0 | 3.97e-01 | 100.0% | 74.0% |