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CAKLQF020000003.1__CAH1076611.1__SAMEA5780031_00867__00194

Bact-Vir

CAKLQF020000003.1__CAH1076611.1__SAMEA5780031_00867__00194

Identity

Kingdom:
phage

Quality

87.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-181
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10136.15 best SpecificRecomb 104.9 5.20e-30 87.8% 24.6%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3dadA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.62 41.0 3.38e-01 93.4% 36.7%
6hftA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 33.0 3.90e-01 93.4% 74.8%
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 36.0 3.94e-01 93.4% 72.4%
4wz9A04 1.25.50.20 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › 0.58 36.0 2.98e-01 93.9% 33.1%
4jykA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 34.0 3.81e-01 73.5% 76.9%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 35.0 3.87e-01 75.7% 77.2%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 36.0 3.98e-01 90.6% 83.6%
2e2eA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 32.0 3.46e-01 97.2% 68.2%
4a64C03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.52 30.0 3.80e-01 84.5% 99.0%
2np3A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 34.0 3.73e-01 78.5% 81.7%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 33.0 3.48e-01 91.7% 70.3%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 38.0 3.91e-01 79.0% 79.2%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3303956 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 35.0 3.91e-01 97.8% 67.6%
3468690 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 36.0 3.81e-01 97.8% 67.9%
4479462 109.4.1.179 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1 0.55 37.0 3.63e-01 96.1% 60.5%
3600392 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 38.0 3.35e-01 97.2% 49.1%
4017850 109.4.1.909 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DOP1_C 0.53 43.0 3.99e-01 97.8% 67.8%
3786019 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 32.0 3.32e-01 93.4% 61.8%
3257990 109.4.1.401 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NRDE-2 0.51 43.0 4.27e-01 89.0% 97.4%
3520646 109.4.1.30 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FAT 0.51 41.0 3.80e-01 98.9% 67.6%
3960828 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 29.0 3.12e-01 94.5% 63.2%
D2 medium residues 182-322
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10136.15 best SpecificRecomb 84.9 6.00e-24 100.0% 21.0%
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.74 44.0 4.61e-01 73.0% 65.1%
5j1gA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 51.0 4.35e-01 76.6% 83.8%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.69 49.0 4.72e-01 73.0% 76.7%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 46.0 5.29e-01 70.2% 99.0%
1tjcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 36.0 4.31e-01 80.9% 80.0%
7smtA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.65 41.0 3.86e-01 71.6% 51.1%
1cgnA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.63 43.0 4.57e-01 73.8% 78.2%
2fefA01 1.20.1440.70 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like 0.62 46.0 4.87e-01 76.6% 88.8%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 44.0 4.79e-01 73.0% 95.5%
7qx4A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.62 54.0 4.55e-01 95.0% 77.4%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.61 45.0 4.72e-01 76.6% 85.9%
4y6cA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 40.0 3.47e-01 84.4% 42.9%
1foeA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.61 46.0 4.11e-01 79.4% 79.5%
5u56A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 45.0 5.02e-01 86.5% 100.0%
2c2lA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 36.0 3.78e-01 74.5% 66.2%
4nx9A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.57 41.0 3.96e-01 73.0% 66.5%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.57 51.0 4.58e-01 97.2% 92.8%
5mlc900 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.56 39.0 4.37e-01 73.8% 94.4%
4ackB00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.55 41.0 4.08e-01 95.7% 73.9%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.54 38.0 3.19e-01 70.2% 88.0%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 38.0 3.74e-01 72.3% 86.8%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 40.0 4.22e-01 93.6% 93.5%
4wr4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 37.0 4.14e-01 95.7% 100.0%
3gw4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 40.0 3.63e-01 95.0% 59.9%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4975983 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.78 56.0 5.62e-01 74.5% 89.7%
3406588 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.75 53.0 4.81e-01 72.3% 72.3%
3393338 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.74 51.0 5.02e-01 75.2% 65.4%
5080053 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.72 46.0 4.77e-01 75.2% 67.4%
3743538 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.71 45.0 5.46e-01 73.8% 97.8%
5068463 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.70 51.0 4.69e-01 75.2% 93.0%
3517330 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.69 51.0 4.42e-01 75.9% 99.5%
3193298 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.69 49.0 3.38e-01 73.0% 31.9%
4946897 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 47.0 4.48e-01 72.3% 90.6%
4927629 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.67 49.0 5.25e-01 85.8% 88.3%
4016984 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.66 47.0 3.28e-01 72.3% 33.9%
3253313 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.65 54.0 4.71e-01 95.0% 59.0%
2884853 5000.4.1.1 alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N 0.63 54.0 4.57e-01 92.2% 77.0%
5082279 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 42.0 4.53e-01 80.1% 78.3%
3289782 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.60 40.0 2.54e-01 71.6% 14.3%
4942632 3352.1.1.1 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3 0.59 50.0 3.44e-01 97.2% 25.3%
3810336 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.57 47.0 4.87e-01 95.0% 93.3%
3809163 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 43.0 3.67e-01 92.9% 49.3%
3520288 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.56 40.0 3.39e-01 71.6% 86.1%
5003254 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 36.0 3.56e-01 79.4% 61.4%
3688613 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.55 50.0 4.49e-01 100.0% 89.7%
3551506 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.54 38.0 3.00e-01 70.9% 83.3%
3408953 109.4.1.403 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1 0.54 46.0 4.64e-01 97.9% 90.0%
3184462 1065.1.1.1 alpha bundles › SPX domain › SPX domain › SPX domain › SPX 0.52 47.0 4.27e-01 100.0% 88.7%
3515566 109.4.1.403 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1 0.51 47.0 3.43e-01 96.5% 66.6%
3540624 109.4.1.403 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1 0.51 46.0 4.18e-01 96.5% 80.0%
3421182 109.4.1.603 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAF1_subA 0.50 42.0 4.18e-01 90.8% 86.7%
D3 medium residues 323-479
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10136.15 best SpecificRecomb 205.9 1.50e-60 100.0% 24.2%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tdoA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.73 68.0 5.68e-01 99.4% 85.2%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.72 37.0 3.82e-01 72.0% 53.1%
3q5dA02 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.69 34.0 4.27e-01 75.8% 76.3%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.69 30.0 3.65e-01 86.6% 60.6%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 35.0 3.95e-01 74.5% 62.8%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 32.0 4.25e-01 73.9% 80.5%
6vqqA01 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.66 60.0 5.00e-01 100.0% 84.4%
1yq1A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 35.0 4.06e-01 72.0% 72.3%
3zojA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.64 57.0 4.74e-01 94.3% 80.2%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.63 34.0 4.18e-01 84.1% 81.4%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 41.0 4.80e-01 79.6% 94.5%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.61 41.0 4.77e-01 83.4% 95.5%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 36.0 3.95e-01 86.6% 71.8%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.60 35.0 3.86e-01 82.2% 69.5%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 33.0 3.92e-01 74.5% 77.6%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 34.0 3.87e-01 84.1% 72.3%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.59 31.0 4.06e-01 83.4% 92.9%
2rd3D00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.58 35.0 3.18e-01 82.8% 41.7%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.58 32.0 3.70e-01 82.2% 73.5%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.57 35.0 3.40e-01 82.8% 52.3%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 4.35e-01 91.1% 84.6%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 36.0 3.92e-01 88.5% 74.6%
2ra1A01 1.20.58.790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 34.0 4.22e-01 78.3% 94.9%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 29.0 3.21e-01 77.7% 60.2%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 41.0 4.51e-01 94.3% 91.5%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.56 39.0 4.39e-01 85.4% 94.1%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 41.0 3.39e-01 76.4% 75.3%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 31.0 3.29e-01 82.2% 59.0%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.54 45.0 3.86e-01 87.3% 86.4%
3pwxA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.53 37.0 3.52e-01 70.1% 78.8%
7xpzA01 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.53 44.0 3.33e-01 89.8% 77.7%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.53 34.0 3.87e-01 82.2% 82.4%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 35.0 3.42e-01 88.5% 60.5%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.53 35.0 3.56e-01 80.9% 66.7%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 35.0 4.05e-01 84.7% 94.6%
7wivA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 3.64e-01 93.0% 87.6%
1n81A00 1.10.3030.10 Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 0.52 32.0 3.02e-01 89.2% 48.9%
2b2hA00 1.10.3430.10 Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains 0.52 42.0 3.16e-01 84.7% 61.4%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 44.0 4.26e-01 89.8% 80.9%
6p6jB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.51 42.0 3.40e-01 88.5% 87.3%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 40.0 3.48e-01 82.8% 71.9%
6o7uc01 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.51 36.0 3.40e-01 83.4% 58.4%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 27.0 3.09e-01 89.8% 67.8%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 41.0 3.71e-01 94.3% 61.7%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964046 5048.1.1.12 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › SpecificRecomb 0.94 90.0 7.09e-01 100.0% 53.8%
3769667 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 34.0 4.12e-01 79.0% 64.8%
3748413 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.71 35.0 4.00e-01 71.3% 61.7%
3248680 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 37.0 4.33e-01 84.1% 73.6%
4008609 1203.1.2.7 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR 0.66 43.0 4.55e-01 82.8% 72.9%
5028679 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.66 38.0 4.64e-01 84.1% 86.4%
3974017 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.64 53.0 5.00e-01 88.5% 75.3%
4024597 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.63 42.0 4.31e-01 93.6% 69.3%
5058642 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.63 52.0 5.04e-01 89.2% 77.7%
3658236 604.12.1.69 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › SRP68 0.63 37.0 4.10e-01 93.6% 72.0%
4564044 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.61 33.0 2.77e-01 73.2% 32.7%
4972007 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.60 38.0 4.04e-01 91.7% 70.0%
5060833 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.60 45.0 3.35e-01 76.4% 79.0%
4608200 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 37.0 4.09e-01 75.2% 76.8%
3966605 601.4.1.84 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › KinB_sensor 0.59 31.0 3.47e-01 78.3% 62.5%
3277476 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 37.0 3.86e-01 89.2% 66.7%
3608835 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 36.0 3.89e-01 77.7% 71.9%
4444459 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.58 33.0 2.72e-01 75.2% 33.1%
3932773 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.58 38.0 3.49e-01 91.1% 50.7%
5077137 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.57 41.0 4.29e-01 83.4% 80.0%
3722421 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.56 42.0 4.44e-01 79.0% 86.4%
3957018 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 43.0 3.79e-01 80.9% 78.4%
4995445 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 43.0 4.02e-01 80.3% 80.5%
3567180 4177.1.1.61 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PLC-beta_C 0.56 43.0 3.69e-01 78.3% 89.2%
4155408 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.56 31.0 2.73e-01 72.6% 37.3%
4092719 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 43.0 3.84e-01 80.3% 76.4%
2462955 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.56 46.0 3.71e-01 89.8% 86.0%
3442617 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 35.0 3.42e-01 89.2% 56.5%
3712596 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.56 51.0 4.70e-01 99.4% 82.0%
3623247 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 43.0 3.84e-01 80.9% 58.6%
3999727 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.55 46.0 3.44e-01 89.2% 94.0%
3941250 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 37.0 4.38e-01 86.6% 98.2%
3197870 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 41.0 4.37e-01 88.5% 91.1%
5037027 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.54 36.0 3.71e-01 80.9% 69.3%
4460746 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.54 41.0 3.97e-01 80.3% 96.7%
4026281 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.53 45.0 4.22e-01 89.2% 75.3%
4112673 310.2.1.1 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF 0.53 42.0 4.03e-01 82.2% 97.8%
3939383 603.1.1.19 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-18_N 0.53 46.0 4.15e-01 92.4% 76.7%
3870558 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 36.0 4.00e-01 82.2% 90.0%
3505434 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 36.0 4.02e-01 84.1% 88.0%
3698437 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 42.0 3.56e-01 84.7% 72.7%
3240462 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.52 36.0 4.15e-01 86.6% 96.5%
3514683 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 35.0 4.00e-01 84.1% 95.5%
3491110 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 35.0 4.09e-01 86.0% 96.4%
3288953 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.52 44.0 3.59e-01 94.9% 84.8%
3289599 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.52 36.0 3.79e-01 70.7% 95.0%
4001786 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.51 37.0 3.40e-01 74.5% 94.3%
3898382 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.51 37.0 4.00e-01 89.2% 90.0%
3665034 2004.1.1.118 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1 0.51 42.0 3.38e-01 87.3% 61.6%
3301462 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.51 36.0 3.67e-01 72.0% 94.3%
3716333 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.51 43.0 3.85e-01 89.2% 71.2%
5020701 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.51 37.0 3.21e-01 74.5% 88.1%
3892495 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.51 34.0 3.87e-01 82.2% 90.0%
4994749 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.51 29.0 3.45e-01 81.5% 80.9%
4994917 3834.1.1.25 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.50 37.0 3.14e-01 74.5% 89.4%
D4 medium residues 480-508_570-639
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF10136.15 best SpecificRecomb 70.5 1.40e-19 70.7% 10.8%
PF10136.15 SpecificRecomb 31.9 6.50e-08 34.3% 5.3%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.68 34.0 3.84e-01 71.7% 61.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.68 42.0 4.72e-01 78.8% 80.5%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 40.0 4.70e-01 72.7% 88.2%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.65 44.0 4.74e-01 78.8% 82.9%
2r9iA00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.65 45.0 5.23e-01 81.8% 100.0%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 47.0 5.23e-01 96.0% 97.4%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 38.0 4.36e-01 73.7% 80.6%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.64 37.0 3.88e-01 75.8% 61.5%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.64 45.0 4.75e-01 92.9% 83.0%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.63 45.0 4.84e-01 90.9% 88.2%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 45.0 3.27e-01 82.8% 27.3%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.62 43.0 3.77e-01 86.9% 47.1%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.62 55.0 4.30e-01 99.0% 46.9%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.61 33.0 4.10e-01 71.7% 89.7%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.61 51.0 4.42e-01 97.0% 59.6%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 54.0 5.39e-01 99.0% 100.0%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 44.0 3.22e-01 76.8% 76.7%
1xo0A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.60 40.0 3.88e-01 90.9% 60.4%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 54.0 4.34e-01 100.0% 69.6%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.60 54.0 5.06e-01 100.0% 96.6%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.60 53.0 5.04e-01 99.0% 91.4%
3rpmA02 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.59 35.0 3.72e-01 74.7% 65.9%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.59 45.0 4.07e-01 79.8% 91.7%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 52.0 4.90e-01 100.0% 93.4%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 44.0 4.51e-01 98.0% 86.0%
2prrA02 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.58 47.0 4.30e-01 86.9% 89.0%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 39.0 3.78e-01 94.9% 62.2%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.57 42.0 4.22e-01 77.8% 78.6%
2lpeA01 6.10.140.1120 Special › Helix non-globular › Helix Hairpins › 0.57 36.0 3.97e-01 81.8% 80.8%
2ozbB01 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 47.0 4.27e-01 88.9% 82.4%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 47.0 4.59e-01 97.0% 82.7%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.56 40.0 3.77e-01 80.8% 60.0%
8cdaB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 43.0 3.72e-01 82.8% 69.8%
3c2gB01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 44.0 2.75e-01 87.9% 15.2%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.56 49.0 4.77e-01 100.0% 89.9%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 49.0 4.79e-01 99.0% 91.7%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 40.0 3.97e-01 80.8% 72.8%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 47.0 4.72e-01 93.9% 93.1%
2vm6A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 41.0 3.65e-01 90.9% 54.2%
2n1rA00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.55 36.0 3.27e-01 81.8% 49.3%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 43.0 4.46e-01 82.8% 93.4%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 44.0 3.83e-01 86.9% 69.3%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.54 46.0 4.03e-01 96.0% 66.0%
2vk9A04 1.10.274.80 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › 0.54 32.0 3.24e-01 76.8% 55.8%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.53 42.0 3.68e-01 85.9% 70.1%
2m4eA00 1.20.120.1930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF16691 family 0.53 26.0 2.86e-01 90.9% 55.8%
1k3kA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.52 38.0 3.40e-01 89.9% 52.7%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 35.0 3.60e-01 81.8% 71.9%
2qksA01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 39.0 3.82e-01 91.9% 73.6%
3d2eA06 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.52 35.0 3.43e-01 80.8% 61.9%
3a06B03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.51 36.0 3.79e-01 85.9% 81.8%
1dxrL02 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.51 39.0 3.84e-01 81.8% 74.1%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.51 43.0 3.99e-01 99.0% 73.1%
3vw4A01 1.10.340.50 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › 0.51 36.0 3.73e-01 85.9% 79.3%
4iv6B01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.50 37.0 3.54e-01 81.8% 65.5%
3rcyB01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.50 39.0 3.46e-01 82.8% 75.9%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3589614 601.1.2.99 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DAGK_prokar 0.76 46.0 4.27e-01 76.8% 48.8%
4013842 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 58.0 4.66e-01 100.0% 45.8%
5051767 4995.1.1.1 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.71 49.0 5.49e-01 83.8% 93.3%
3971109 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.70 45.0 5.06e-01 79.8% 85.3%
4565834 106.1.1.11 alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.70 64.0 5.48e-01 99.0% 99.3%
3235302 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 46.0 3.38e-01 87.9% 26.3%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.69 46.0 4.63e-01 79.8% 67.0%
4948961 164.1.1.1 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 0.69 49.0 5.29e-01 83.8% 87.1%
3714252 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 57.0 4.13e-01 92.9% 46.0%
3506685 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.66 43.0 4.80e-01 90.9% 88.0%
3394519 109.4.1.557 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TTC7_N 0.66 48.0 3.83e-01 77.8% 89.8%
3401991 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.66 45.0 4.42e-01 76.8% 64.5%
4481405 604.39.1.30 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › SpoIIE_N 0.65 52.0 4.74e-01 86.9% 91.9%
5040210 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.65 38.0 3.93e-01 70.7% 60.0%
4038171 4044.1.1.1 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane 0.65 40.0 4.20e-01 75.8% 67.8%
3936678 164.1.1.0 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II 0.64 46.0 5.05e-01 81.8% 92.5%
3687916 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.63 55.0 4.84e-01 100.0% 65.5%
3627448 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.63 45.0 4.42e-01 82.8% 67.3%
3947894 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.63 44.0 4.83e-01 88.9% 90.0%
4344623 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.62 53.0 4.11e-01 91.9% 86.7%
3990526 4177.1.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › IMD 0.62 46.0 3.45e-01 76.8% 64.8%
3338006 109.7.1.0 alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.62 43.0 4.02e-01 92.9% 58.3%
3914708 109.4.1.25 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DIL 0.61 55.0 3.66e-01 99.0% 31.4%
3737926 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.61 54.0 4.47e-01 98.0% 62.8%
3821321 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 45.0 3.91e-01 76.8% 50.7%
4890998 148.1.3.28 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_11 0.61 39.0 2.79e-01 78.8% 21.5%
3605105 1189.1.1.3 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP 0.61 55.0 4.31e-01 100.0% 89.0%
3707590 5079.1.1.4 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › TM_HPP 0.61 50.0 4.21e-01 88.9% 80.6%
3586382 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.61 38.0 3.85e-01 76.8% 62.0%
3710592 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.60 45.0 4.67e-01 88.9% 83.2%
3995294 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.60 53.0 4.95e-01 99.0% 77.6%
3615723 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.60 55.0 4.55e-01 100.0% 94.7%
4569675 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.60 51.0 5.04e-01 92.9% 97.1%
3453526 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.60 42.0 3.92e-01 87.9% 57.6%
3590073 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.60 42.0 4.53e-01 86.9% 85.9%
3408266 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.60 54.0 4.71e-01 100.0% 73.3%
3801933 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.60 42.0 3.92e-01 82.8% 58.4%
3497136 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.59 42.0 3.87e-01 86.9% 56.2%
4160719 6102.1.1.1 alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA 0.59 48.0 4.04e-01 85.9% 65.6%
3647188 3930.1.1.0 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.58 43.0 4.00e-01 84.8% 62.5%
3640060 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.58 52.0 3.83e-01 100.0% 63.2%
3800823 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 50.0 4.99e-01 97.0% 90.5%
3272490 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 42.0 3.83e-01 75.8% 75.4%
3792010 604.1.1.105 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1_2 0.58 50.0 4.93e-01 97.0% 90.5%
3923182 174.1.1.43 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 0.57 51.0 4.50e-01 100.0% 71.3%
1868087 622.1.1.2 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA 0.57 46.0 4.86e-01 93.9% 100.0%
4111537 633.23.1.32 alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.57 51.0 4.35e-01 99.0% 69.4%
3203936 109.4.1.31 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MA3 0.57 46.0 3.36e-01 88.9% 36.7%
3740645 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.56 44.0 4.62e-01 89.9% 93.3%
3973441 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.56 41.0 4.36e-01 84.8% 84.4%
4015041 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.56 50.0 4.13e-01 100.0% 93.9%
3221759 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.56 50.0 4.04e-01 100.0% 84.7%
3585209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 48.0 4.42e-01 99.0% 74.8%
3520105 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.55 49.0 4.24e-01 99.0% 65.2%
3684359 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.55 49.0 4.32e-01 98.0% 71.0%
3662240 601.1.1.70 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › ROH1-like 0.55 42.0 3.87e-01 80.8% 90.8%
4654652 633.21.1.23 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 0.55 47.0 4.27e-01 97.0% 79.3%
3837882 150.1.1.196 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF27018 0.55 44.0 3.92e-01 87.9% 83.4%
3670742 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.54 39.0 3.74e-01 75.8% 97.5%
3845930 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.54 45.0 4.06e-01 91.9% 85.0%
3655088 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.54 49.0 3.33e-01 100.0% 71.0%
3243410 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.53 48.0 4.08e-01 99.0% 78.8%
3711833 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 44.0 3.74e-01 91.9% 67.3%
5036274 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.52 37.0 4.01e-01 83.8% 92.5%
4874207 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.51 39.0 4.07e-01 90.9% 86.8%
3903076 632.11.1.9 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › PIG-S 0.51 40.0 3.57e-01 81.8% 60.0%
3651408 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.51 41.0 3.33e-01 93.9% 44.7%
4978581 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.51 34.0 3.45e-01 89.9% 69.0%
D5 medium residues 509-569
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10136.15 best SpecificRecomb 81.2 8.20e-23 100.0% 9.6%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1uxtA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.67 58.0 3.83e-01 100.0% 74.7%
4i9oA00 1.10.246.20 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Coactivator CBP, KIX domain 0.62 42.0 3.91e-01 70.5% 76.9%
1iv8A04 1.10.10.470 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Maltooligosyl trehalose synthase; domain 4 0.59 44.0 3.87e-01 83.6% 62.9%
1n69B00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.59 46.0 4.29e-01 90.2% 68.8%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 40.0 3.83e-01 73.8% 60.8%
1pduA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.57 44.0 3.06e-01 86.9% 38.7%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 44.0 3.85e-01 86.9% 56.7%
6b8hO01 1.10.520.20 Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase 0.55 37.0 3.29e-01 73.8% 44.4%
1wmwB00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.54 46.0 2.98e-01 100.0% 31.3%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 39.0 3.13e-01 77.0% 39.0%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 38.0 3.81e-01 77.0% 85.7%
1xfxA01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.53 41.0 2.90e-01 90.2% 39.0%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 37.0 3.54e-01 75.4% 87.3%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 42.0 3.47e-01 96.7% 54.8%
1gaxA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.50 40.0 2.87e-01 96.7% 58.1%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3503444 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.53 36.0 3.30e-01 75.4% 50.0%
3802185 192.8.1.359 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF641 0.53 39.0 3.78e-01 80.3% 82.9%
3441655 3567.1.1.88 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PGG 0.52 40.0 2.98e-01 88.5% 86.5%
4181677 192.29.1.272 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Val_tRNA-synt_C 0.52 36.0 3.54e-01 75.4% 92.9%
4376762 140.1.1.5 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.52 38.0 2.71e-01 93.4% 24.5%